Basic Information

Insect: Anopheles sinensis
Gene Symbol: -
Assembly: GCA_000441895.2
Location: KE525315.1:1071078-1073420[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 5.2e-06 0.00037 20.6 2.3 1 23 99 121 99 121 0.98

2 15 0.00056 0.04 14.2 4.0 1 23 129 151 129 151 0.96

3 15 7e-06 0.0005 20.2 0.2 1 23 160 182 160 182 0.98

4 15 1.3e-06 8.9e-05 22.5 5.2 1 23 188 210 188 210 0.98

5 15 0.0035 0.25 11.7 0.2 2 23 218 239 217 239 0.97

6 15 0.0002 0.014 15.6 3.3 1 23 245 268 245 268 0.94

7 15 0.0019 0.13 12.5 6.2 1 21 274 294 274 295 0.94

8 15 0.022 1.6 9.2 3.3 3 23 303 324 301 324 0.94

9 15 6.5e-06 0.00046 20.3 0.7 1 23 359 381 359 381 0.97

10 15 0.0014 0.097 13.0 0.1 1 23 392 414 392 414 0.93

11 15 1.9e-06 0.00014 21.9 2.9 1 23 444 466 444 466 0.99

12 15 0.13 9.5 6.7 4.2 2 23 501 522 500 522 0.94

13 15 0.12 8.2 6.9 7.2 1 23 528 550 528 550 0.98

14 15 1.5e-07 1.1e-05 25.4 1.5 1 23 558 580 558 580 0.99

15 15 0.00047 0.033 14.4 0.8 1 23 586 609 586 609 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	5.2e-06	0.00037	20.6	2.3	1	23	99	121	99	121	0.98
2	15	0.00056	0.04	14.2	4.0	1	23	129	151	129	151	0.96
3	15	7e-06	0.0005	20.2	0.2	1	23	160	182	160	182	0.98
4	15	1.3e-06	8.9e-05	22.5	5.2	1	23	188	210	188	210	0.98
5	15	0.0035	0.25	11.7	0.2	2	23	218	239	217	239	0.97
6	15	0.0002	0.014	15.6	3.3	1	23	245	268	245	268	0.94
7	15	0.0019	0.13	12.5	6.2	1	21	274	294	274	295	0.94
8	15	0.022	1.6	9.2	3.3	3	23	303	324	301	324	0.94
9	15	6.5e-06	0.00046	20.3	0.7	1	23	359	381	359	381	0.97
10	15	0.0014	0.097	13.0	0.1	1	23	392	414	392	414	0.93
11	15	1.9e-06	0.00014	21.9	2.9	1	23	444	466	444	466	0.99
12	15	0.13	9.5	6.7	4.2	2	23	501	522	500	522	0.94
13	15	0.12	8.2	6.9	7.2	1	23	528	550	528	550	0.98
14	15	1.5e-07	1.1e-05	25.4	1.5	1	23	558	580	558	580	0.99
15	15	0.00047	0.033	14.4	0.8	1	23	586	609	586	609	0.96

Sequence Information

Coding Sequence: ATGGACTACAATGCATACAACAACAAGCTGTATGCCGGGGTGTCACAGCCCATTCCCGGGAGCTCCGGGTTCTTTCAGCCAAGTGCCGCAACACCGACGTTTCTTAAGGTCCCCAATCCCGCGCTGATCAAGCAAGAGTCTGCGGCGTACATAGTACATCGGCAACCGGTGGTTCCGGTGCAAATGATGAAGGAAGAAACATTTTCTCCCGCAGTTCCCGTAGCTGCCAGTTACACTCCAACGACCGTGGAAACCCCACCGGCACCGGTTCCAGTCGTTTCGCAAGTAACGCGTTTTAGCTGCGATTCCTGCCCGAAGACGTTTGACACGAAATCGAAGCTAGAGAAACACAGCAAGACGCACCTGGCGTACGAGGAGCAGGTCTTCAAGTGTCGCATGTGTGATAAGATCTTTCGCACCAAGAGCACCCTTATCTGCCACGAGAAGGTACACGGCGAGAACGGGGTGGACAATAGCTTTTCGTGCGTGGAGTGTGGAAAGGTGTTCGCTTCGGACGATAAATTGCAGGTCCACCGGAGGTTGCACACTGGGGAAAAGCCGTACCAGTGTAAGGTGTGCCAAAAGTGCTTTAATCATCAGTCGAACCTGATCGTGCACTCGCGGATTCACGAAAAGGTAAAGAAAGCACTGAAGTGCGATCGGTGCAGCAAGGTGCTGGACAATGAGGAGCGCCTGGCCATTCACATGCGGTTGCATACGGGCGAAAAGCCATACAAGTGTTCGTACTGCGAGAAGCGCTTCAATCACAAGAGCACGGTAAGCACGCACGAAAAGGCGGCCCATATCGCGGCCAACTCGTTCAAGTGCGACCGGTGTCACAAAACGTTCAATCAAAAGTGCCAGCTGCAGTATCACGAGAAACTGCAGGAAGAGCACACGATCGCGTGCACCCTCTGCGATAAGGTGTTCTGCTACAAGGCAAGCCACAAGGAGCACATGTTTAAGGTGCATCTACCGCGGCCGAAGAAGGAACCGAAAAAGGAACCGTCGGGCTCGGGGACCGAAGGTCCCGGTGCGGCATCCGGTGGGACCGGTTCCCAGGGTCGCAACAAATTCAAATGTACCGTTTGCGATCGCCGGTTTTACTACAAGCGAGCGCTCGAAGTGCACATGGGCGTGCACGATGCGTCGTTGGATGTGAACGTGCTGCACTTCTCGTGCAACTACTGCCCAGAGACGTTCACCGAGGAAGAACCGTTGGAGCAGCACGAGGCCGAGCACGTGGCACGCGGAACGACGGACTTTCTCGTGAACATGAAAGCCCTCGAGCAGTCGGAAAATCCCGCCAACGGTCAGGTGGACGGAGGGTTCCGGTGTCCACTGTGCTTCAAACGGTTCGACGATCAGTCGGCACTACGCGAGCACCACCGGACGCATCTCTGTACGCGCACCGATTGCACCAAGTGCGAACGGGCCCGCGGGGACGAGTTCGATATCAACATCAGCACGTACGAGCCGGAAGAGGATGGGCGCGAAACGGTGTGCAACATTTGCCACCGGACGCTGCCCTCGTTCGAGCAGTTCCAGAACCACTTCCACTACCATACGTCCCGGGTGCCGTTCTACTGTTTTCACTGTCGGGTGGAGTTTCACGACAAGCGCGAACTGTACACGCACTCCCGCACACACTCGCCGCGCGAATTGGAGTCGTACACGTGCGAGATCTGTGCGAAGGTGTTCTCGACGAAGGGCAACTTTAAGCGCCACCTGAAATCTCACGAAACGGTCCGGGCGTTCGCGTGCGACCGATGCTTCAAGCAGTACGACTATAAGAGCGCCCTCGAGGCACACTTGAAGCGATCCCACGGTATCGAGTTGTAG
Protein Sequence: MDYNAYNNKLYAGVSQPIPGSSGFFQPSAATPTFLKVPNPALIKQESAAYIVHRQPVVPVQMMKEETFSPAVPVAASYTPTTVETPPAPVPVVSQVTRFSCDSCPKTFDTKSKLEKHSKTHLAYEEQVFKCRMCDKIFRTKSTLICHEKVHGENGVDNSFSCVECGKVFASDDKLQVHRRLHTGEKPYQCKVCQKCFNHQSNLIVHSRIHEKVKKALKCDRCSKVLDNEERLAIHMRLHTGEKPYKCSYCEKRFNHKSTVSTHEKAAHIAANSFKCDRCHKTFNQKCQLQYHEKLQEEHTIACTLCDKVFCYKASHKEHMFKVHLPRPKKEPKKEPSGSGTEGPGAASGGTGSQGRNKFKCTVCDRRFYYKRALEVHMGVHDASLDVNVLHFSCNYCPETFTEEEPLEQHEAEHVARGTTDFLVNMKALEQSENPANGQVDGGFRCPLCFKRFDDQSALREHHRTHLCTRTDCTKCERARGDEFDINISTYEPEEDGRETVCNICHRTLPSFEQFQNHFHYHTSRVPFYCFHCRVEFHDKRELYTHSRTHSPRELESYTCEICAKVFSTKGNFKRHLKSHETVRAFACDRCFKQYDYKSALEAHLKRSHGIEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00094080;
90% Identity: -
80% Identity: -