Aqua009556.1
Basic Information
- Insect
- Anopheles quadriannulatus
- Gene Symbol
- -
- Assembly
- GCA_000349065.1
- Location
- KB667444.1:4116932-4122009[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.24 12 6.1 0.1 2 23 195 217 194 217 0.91 2 9 0.094 4.6 7.4 2.6 1 21 990 1012 990 1014 0.93 3 9 0.44 22 5.3 0.9 2 20 1025 1044 1024 1048 0.92 4 9 2.2e-07 1.1e-05 25.1 1.4 1 23 1084 1106 1084 1106 0.98 5 9 0.001 0.051 13.5 0.6 2 23 1169 1191 1168 1191 0.92 6 9 0.00021 0.01 15.7 1.3 1 23 1208 1230 1208 1230 0.96 7 9 0.037 1.8 8.6 6.8 1 23 1236 1258 1236 1258 0.98 8 9 0.00081 0.039 13.9 2.4 1 23 1266 1289 1266 1289 0.97 9 9 0.22 11 6.2 0.7 1 23 1298 1320 1298 1320 0.98
Sequence Information
- Coding Sequence
- ATGGATATATTTCAAAACCAATGCAGCGAGAGCTTAGGCTTCGATTCGATGCTTTCGTCGAACCATCTACACTCACCGCTGCACGATTCGCCCTGCTCGCCGACGAACCCGTACGCACCATCGTCGCCCTACTTTTCCTCCATCTCGCAGCAGCCGACTGGCCACACCAGCGGACCGAACGATGTCATCCTGCCGAGCATTTTCGTCAAAATTCCGACCCAAATCAACCAGCAGTACCAGCAGCAGGAAAGCCGGCTGCTCCGGTCCACCCATCATAGTACCGCGAGCGAAATCAAGTGCGAGGAACGGTCGGACTCGATCAAAAGCGAGATAGCCGATACGCGGGTACGGCTAGCGGGGAATGGTCTTGCCAGCGTCGATCACCGGCTGCCGGACGTGATCGATAACTATCTAAACGATACGGACCGGGTGGAGCCGGCGGAGGTGGAGCCGAACGTGCGCACGTGTGACCGTTGCCCTTTTGCCACCCTTTCGGAGGTGCGGCTGAGCGAGCATCGACGCGAAAGGCATCCGGGGGGTGGTGTTGGTGTAGGGCCACAAGAGTCGCAGGCGGAAAAGCTAAGCTGTCCGGTATGCGAGAACAAATTCTACAAAAAAGCCGTACTGGAGCTGCATCTTACCGAGGACCATGAAATGTTGGCCAGCGAGGTCGCAGCATTGGGCCACAGTACCGTCACAACCCTCCAGTCGGAAAGGGGTACTGCACCGGAAGTTAGAATCGAACCGGCTATTCAGCAGAACTGTACCGAGATTCCGCCGGGACCCCCGGCTGCTACCCCTACGGCAACGTCGACGGCGACACACAGCAAAAGCCGGATCTACATAAAGGACGTACAGTTGCTGAAAAAGCCGGACGTGATTGCGCAGGAAAGCCATGACGCGCAGGGCCAGCAGCTGCTGTCGACGGAGCAGGAACCGTCCGCGATAGCGCACGGTACGCTACAGGACAGCCATCAGCTGTCGCTCGGCGAGGACATGTTGCCATCGCTCGATCAGTCGCTGGAGCTACCACCGCAGCAGCAACCATGCGCCGTCAGCGGGAACAAAATCTTCATCCGCAACGTGTCGCTGCTGCAGAATGTGAATTTCGTCGCCTCGGCGGAAAACATGCTCACGAATGGGAACGGGAATCGGTACGGTACGGCACCACCACCATCACCACAACCACCGCCGCCGTCCTCCTACCTGAGCATGGACTGTGCGAACGATGGTTCCGGGGCGCTGCTGGACACGATCAACGGTGGGTATGGTGGAACGATTGCAGCACAACCTGCTCCATCCGCAGTAGCACAATCATCCCGGGGTAGTCGTATCTACATTAAAAACGTTGATATACTACGGAACCACCCGCTCATAGCGCTCGATGACCCCGGGGTGACGTGCACGAATTCGCTCTCCACGACGACGTTCAGCGAATCGATCACGACGAGTAGGGCGAGTAGCTGCGAGAGTATCATCTGCACGTCCACACCACCGGCCACGGCGACGGAACAACAGCAACCACCGACCGTGCCCGTACCATCGTCCATGACGAACAACTCCTTAGGAGCAGTGTCACAAGCGAACGATCAACCGCTTTTGCATGGCACCGAAATTAGCTATGCCACCGTTGGAGGGGACGCGATGGGAAACCCGGCCCGGCCATTGCCACTAGCCGTGGATCAAGGTTCGCAGAACTTGCTGATGCTGTTTTCCACCTCGTTGGACGGTACCCCGGGCGGTGGATCGGTTGGTGAGCCTAACGTTTCCTACCTGACCGCAAGCACCAACATGACCGTGCAGCAGGGTGGCGAGTACGGTACGCTTCCACAACCACCACCACCACCACCACCGGCACAGTGCGATGTTCAGCAGCAAACCACCGGCGACGTACCGCAGCAACAGCCAAGGAAGAGCAAAATATTCATCAAAAACATCAGCGTGCTCAAGCAACCGACCATTCATCTGAAATCAGTCGACGAGGTGAATCTGATGACGTACGACGAGCTGCAGAACATACTGCCTCCCGTCGGCGGGATGTCCTCCCAGGTGGGGATGGACTGTGGAGGAGACACCATTGGTGGACCATTGGAGCAGCACGAAGCACACGAACAGCACACGCTGGACGGGGCGAACCGGTTGGACAAACCGTTCGGTGGGATGATTGAAATGAACGCGCACCATTCGCCCGAGCTGGTCGAGCACGGTAATGTCGAACAGCACGGCGATGGCGACGACGATGACGTTATGGATGGGTACCACGAGTCGGATCTCGGCTACGGTGAACTGAGCGATGTGTGCGACTTTACCGAAGGTTTCAACGATCGAGACGATCCCGGCGGAGGAGGAGCAGGAGGAGCAGCAGGAGCCGGTGGTATCGATATGACGGCGTGCACAGCCAATGATGACACGAACCGTAACGGTCACTTGGTGGCGGAATCGACCCACTGTGAGCCAACGCTTCCGCCCGGGTCCGGTTTTACGGGCGACATTATACTGCTGCAGGAAGAATCGGATGCAAGCGAGAAGATCACGCCGAACCACGAATGGTCCGCGATCGTCGAGCCGGCGAATGGCGGTGGGCCACCGTTGGGGCAGGACATTTTGCAGCAACCGATGGAAATGTCTGACGGCAACGAAGCTAATCCGTTGCGTCGAGAGGAAGATCAGCTGCTTGGCAACTCTCACCCACATGTGATCAATCTCGATCCTCCCAATGAGTATCACCCACCGGTTGGCGATAGTGACGCGATCGTACTGGCCGCTGCTGTGAATCCATCGATCGGGGAGACCCAACAACCGGTGGATGCATTAACACCATCCCAAGAAGAGGCGAATGTGTCGGGCGTCACCGCACTTGCTGAACCAGATCGTCCCCGTACCCGTGGACGGCCAAAGGGGGCGAAACAGACCGGCATCACCAAGCTGAAGAAGCTCTACACCAACCTAACGGTCGAGGAGGAAGGCTACAAGTGTGACCTGAAGGACTGTGGCGTGCGGTTTCGCCAGCCAGATCGGCTCGACTACCACCGCAAGTGTCACGTGGTGGCGCCCGACAGCCCCAATCCCATCCACTGTCCGGAGTGTGGTTCGCTCGAGTTCCGCAACTGGAACACGCTGCACACCCATCTGTGGCGGGAGCACGCGATCGACATGGAGCTGTACGCGTGCCATCTGTGCAGCTTCAAGACGCCCGTCCTGTGCCGGCTGAACAACACGCACATGAAGATCCACTCCGAGGAGCGCAACTTCAAGTGTGCCATCTGTGGGAAAGCGTTCAAGAACAACAAGCAGCTCCGCAATCACCGCCGGTGGCATCGGGAACCACAGCAGCAGCAGCAGCAACCGCAACACCAAGAAGCACCCGTGTTGGAGGAGTCACAGCCGGTCAGTCAACCACCACCGGTGGAAGAACCTCCCGCGATCGGCCCAACCCAATCGAGCGATGCGTCCCAGGGCGACAAACCGAAAGCAAAACCCACCTCCATCCAGCAATCCACGATGAAGTGCGTCAAGTGTGGGCTGCGGTTCGCGGGCAAACGCCAGCTAAGGACGCACATGGACGCAAAGCATCCCACCGAGGCGGGCGAGCCGGGGTCGACGGAGGTGAGTGCCGCTAAGCATCGCTGCCTACTGTGCGGTATGGTGTTCCGGACGCGCTACCTGCTCCAGTCACACGCGGCCAAGCACTCGGACGAGAAGCGGTTCAAGTGCGAGCATTGCGAGTACACCACCAACGACCACAACGCGTTCCGGCGGCACAAGATGCGCCACAGCACCAAGGGTGGCCATATGTACAAGTGCAGCTACTGCGATTACAGCAGCATCCAGAGCACGACCTACCGGAAGCACCTGGAGCGGATGCATGCGGAGGTCGCCTCGGCCCTGCTGTACAAGTGTGCCAAGTGTCCGTTCGTGTCGATCAGCGAGGCCAAGTATCAGCTGCATCGAACGAAACACCAGGAGGAGGGAGGGGAAGCGCGAGAGAGACCGGCGGCACTGGGGGTGGAACCGGTGCAGGAGAACGACCTTGAGCAGCAGCAGCGACAGTGCGAAAGCGTTAACTCGGACGTGGTGATTGTGGAGCAGCAGCAGCAGCTTGATGCCGTGGCGAACGGGTTAAGTACGTCACCGATGGATGTGGAGCTGCTGGGCGGGGATGCAGCTGGCGGGGGTCTACAAATCATTCAGCATCCCATCATCCGGCCGGCAATGTTTGCGAACAATTTCTCCAAGGTGGACAACTTCTACGGCTATCAACCGGCCCAGCAGCATGGTCAGCCCTTCGCGCCTTCGCCACGTGGTATGTGCCCCTCTCCGCAAGTGTCTTGCGCGGTCGGTTTGATGCCTACGCCAACCACTCCCATTCCGGTGCCAGTGTCCGGCCAGCTAGTAACCGAGCAGCACGAGTACGTGCATCTAGCTAACGCAGTAACCGGCGATGTCCTAATGAGGGAGCTTAATTAG
- Protein Sequence
- MDIFQNQCSESLGFDSMLSSNHLHSPLHDSPCSPTNPYAPSSPYFSSISQQPTGHTSGPNDVILPSIFVKIPTQINQQYQQQESRLLRSTHHSTASEIKCEERSDSIKSEIADTRVRLAGNGLASVDHRLPDVIDNYLNDTDRVEPAEVEPNVRTCDRCPFATLSEVRLSEHRRERHPGGGVGVGPQESQAEKLSCPVCENKFYKKAVLELHLTEDHEMLASEVAALGHSTVTTLQSERGTAPEVRIEPAIQQNCTEIPPGPPAATPTATSTATHSKSRIYIKDVQLLKKPDVIAQESHDAQGQQLLSTEQEPSAIAHGTLQDSHQLSLGEDMLPSLDQSLELPPQQQPCAVSGNKIFIRNVSLLQNVNFVASAENMLTNGNGNRYGTAPPPSPQPPPPSSYLSMDCANDGSGALLDTINGGYGGTIAAQPAPSAVAQSSRGSRIYIKNVDILRNHPLIALDDPGVTCTNSLSTTTFSESITTSRASSCESIICTSTPPATATEQQQPPTVPVPSSMTNNSLGAVSQANDQPLLHGTEISYATVGGDAMGNPARPLPLAVDQGSQNLLMLFSTSLDGTPGGGSVGEPNVSYLTASTNMTVQQGGEYGTLPQPPPPPPPAQCDVQQQTTGDVPQQQPRKSKIFIKNISVLKQPTIHLKSVDEVNLMTYDELQNILPPVGGMSSQVGMDCGGDTIGGPLEQHEAHEQHTLDGANRLDKPFGGMIEMNAHHSPELVEHGNVEQHGDGDDDDVMDGYHESDLGYGELSDVCDFTEGFNDRDDPGGGGAGGAAGAGGIDMTACTANDDTNRNGHLVAESTHCEPTLPPGSGFTGDIILLQEESDASEKITPNHEWSAIVEPANGGGPPLGQDILQQPMEMSDGNEANPLRREEDQLLGNSHPHVINLDPPNEYHPPVGDSDAIVLAAAVNPSIGETQQPVDALTPSQEEANVSGVTALAEPDRPRTRGRPKGAKQTGITKLKKLYTNLTVEEEGYKCDLKDCGVRFRQPDRLDYHRKCHVVAPDSPNPIHCPECGSLEFRNWNTLHTHLWREHAIDMELYACHLCSFKTPVLCRLNNTHMKIHSEERNFKCAICGKAFKNNKQLRNHRRWHREPQQQQQQPQHQEAPVLEESQPVSQPPPVEEPPAIGPTQSSDASQGDKPKAKPTSIQQSTMKCVKCGLRFAGKRQLRTHMDAKHPTEAGEPGSTEVSAAKHRCLLCGMVFRTRYLLQSHAAKHSDEKRFKCEHCEYTTNDHNAFRRHKMRHSTKGGHMYKCSYCDYSSIQSTTYRKHLERMHAEVASALLYKCAKCPFVSISEAKYQLHRTKHQEEGGEARERPAALGVEPVQENDLEQQQRQCESVNSDVVIVEQQQQLDAVANGLSTSPMDVELLGGDAAGGGLQIIQHPIIRPAMFANNFSKVDNFYGYQPAQQHGQPFAPSPRGMCPSPQVSCAVGLMPTPTTPIPVPVSGQLVTEQHEYVHLANAVTGDVLMRELN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00102583;
- 90% Identity
- iTF_00101288;
- 80% Identity
- -