Basic Information

Insect: Anopheles quadriannulatus
Gene Symbol: -
Assembly: GCA_000349065.1
Location: KB667533.1:233194-236226[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.4 69 3.7 1.6 2 23 214 236 214 236 0.94

2 17 0.0013 0.066 13.2 0.1 2 20 246 264 245 266 0.94

3 17 0.069 3.4 7.8 0.5 1 20 273 292 273 294 0.95

4 17 0.72 35 4.6 2.2 2 23 419 441 418 441 0.92

5 17 0.98 48 4.2 1.1 1 21 453 473 453 474 0.93

6 17 0.0099 0.48 10.4 1.6 1 21 481 501 481 506 0.92

7 17 0.00083 0.04 13.8 1.3 3 23 584 605 583 605 0.90

8 17 1.4 67 3.7 0.1 1 20 618 637 618 639 0.87

9 17 0.018 0.86 9.7 2.8 1 21 648 668 648 673 0.92

10 17 0.026 1.3 9.1 0.7 2 23 739 763 738 763 0.84

11 17 2.6 1.3e+02 2.8 0.6 2 20 780 798 780 800 0.92

12 17 0.0013 0.063 13.2 0.3 1 23 807 830 807 830 0.94

13 17 2.2e-05 0.0011 18.8 0.1 1 23 837 859 837 859 0.98

14 17 1.8e-05 0.00087 19.1 2.4 1 23 865 888 865 888 0.96

15 17 0.0001 0.005 16.7 0.6 1 23 894 916 894 916 0.98

16 17 0.0072 0.35 10.9 2.5 1 23 922 945 922 945 0.93

17 17 1.6e-05 0.00079 19.2 0.7 1 23 951 973 951 973 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.4	69	3.7	1.6	2	23	214	236	214	236	0.94
2	17	0.0013	0.066	13.2	0.1	2	20	246	264	245	266	0.94
3	17	0.069	3.4	7.8	0.5	1	20	273	292	273	294	0.95
4	17	0.72	35	4.6	2.2	2	23	419	441	418	441	0.92
5	17	0.98	48	4.2	1.1	1	21	453	473	453	474	0.93
6	17	0.0099	0.48	10.4	1.6	1	21	481	501	481	506	0.92
7	17	0.00083	0.04	13.8	1.3	3	23	584	605	583	605	0.90
8	17	1.4	67	3.7	0.1	1	20	618	637	618	639	0.87
9	17	0.018	0.86	9.7	2.8	1	21	648	668	648	673	0.92
10	17	0.026	1.3	9.1	0.7	2	23	739	763	738	763	0.84
11	17	2.6	1.3e+02	2.8	0.6	2	20	780	798	780	800	0.92
12	17	0.0013	0.063	13.2	0.3	1	23	807	830	807	830	0.94
13	17	2.2e-05	0.0011	18.8	0.1	1	23	837	859	837	859	0.98
14	17	1.8e-05	0.00087	19.1	2.4	1	23	865	888	865	888	0.96
15	17	0.0001	0.005	16.7	0.6	1	23	894	916	894	916	0.98
16	17	0.0072	0.35	10.9	2.5	1	23	922	945	922	945	0.93
17	17	1.6e-05	0.00079	19.2	0.7	1	23	951	973	951	973	0.99

Sequence Information

Coding Sequence: ATGCTGCGAAGACCGTCGAAGCGAAGAAAAGTGTCCAACGTGAATGAAGAAGAAACGGAATTCACGCCAGCGTCTGTTGAGCAGAAATGCTGCATCTGCTCCAAACATCCAAAGGGCGATTTGCTTGAACTTTCCACTGTTGTAGAATCGGGCAGCTCCCTCACCATTGCCACCGTCGTCGAGCAGGTGGCCTCCATCAAGGTAAACAATGTCCAGAAGAGCATTTGCGGTGGTTGTTGGACCAAAATTCAGGCGGCCTACTCGATACAGAAGGAAATCCGCGGATCAGAATGTATGGCACAGCAGGATGTCGAGTGCTACAGCGAGACTGAGGAAGAGAACGCGGAAAATGCCAACTGTACCGAGCAGGACGATCCGGACCCGCTCGTCGTAGATGGCATCGACGAGAGTGAATATTGCATCGAATATCTGGAGGAACAGGAGGAAGAGCAGCAACCACCTGCAAAGGAAGAAGCCGCAGACATTGAGATTGAAGCATGCTGCTCCGACGAGGAAGAGCACGAAGAGCTCCGAGCGGACGGTGGTAAGGTGACGCGTCAGTTCCAAATGCCAAATGAGGCCACGATCGTGGCCGACGTACTGCACGAGCAGTATCGGATGGTGGAGGTAACCGGGGAACGGTGCTGCGGGTGCAGCTTTGTCGCACGTTCACGCAAAGAGCTGCTGCAACACTCGGAAACGGTCCACTCGGTCGAGATGACCGACCACGGCGACTACTGTCCGATTTGTTTCTACAAATTCTCCACCGATCAGCAGCTCGAGCGCCACATCGATGAGTTTAAGCTGAACAAGATGTACGTGTGTTTGCGCTGCAATCGGTTCTACAACGTGAAGCGGAAGCTGTTTAACCACCTGATCGGATGTGGTGGCATGGTTGAGGAGGTGGATGTGCAGGCAAGCGGAACGAACAATGATGATGCACTTACGATCGAAGCCCTGAAAGAGGAGGACGGGGAAGAGGCGGAAGGGCTGGAGGAAGATAGTCAGTATGAGGAGTGTTACCTGCAGGAAGGCACGGACACGGACGAACAGCAAGAGCTGCACCCGGAGGACCGCCTACAGAACGCAACCGATCCACGTGTGATGCATCGCTACAAAGCACTGTTCGAAGAGGTGCTGTCGAACGAAGAGCTTTACTGCCAGCTGAGCGAGAAGGAACTGAACGTGCAGGATGTGCAGATCGCGGAGCAGCACGTGTTCGAAACGTTCAAGTACATTCGGTTGCGGGGATTGCGCTGTTGCGGGTGCTCCTACACCTGCATGTCCAAGGCGCTGCTGATTGAGCACAGCAATCTGGCCCATCCGCCCGAAGATCCGTCGCAGCACGTTGATGAGCATGCGTGCGAGCTATGCCGGGCGGAGTTTCAAAACACGCTGAATCTCGTGAAGCACATCTGCTTCTTCACCACCCGGCAGCTGTTCCTGTGCACGGTGTGTGACGTTTCGTTTCTGAACAAGGAAAGCTTGCGGAACCACCAGCGCCACAACGAACGGCACCGCGAGCTGGAGAACTACAAGTTTGAGCAGGCCGGCATCGAGCTCGACACAGCGGAAGGGTTTGTCGAGCTCGACCAGCCGGCTGTGGCCGACGAGCTGCGCAAGCTGGTGGTGGAAAAAAATAGCTACCGGCCGAAAGCGGTCACCTGCATTCCCATGCCGGACGAACGGTTCATCCGGCGGAGGAAGGAGTACAACAACTACAGCGTCCTGGTCGTGGCTGGCGAGTATTGCTGCGGGTGTGGCAAGTTCTTCGATACGACTTCCGAGCTGCAGCAGCACGCCGAGCAGGAGCACTACTTGCCGCTCAATTATTGTGCCCGCACGTACGGCCACCAGTGCGAGATCTGTTACGCTGTGTTTGAGCTGGAGCGGGGCTTCGCGGTGCACCGGTCGATGAGTCGCTCCAAGCCAAAGACGCTGTACCTCTGCAAACTCTGTGGGCTGCTGTTTTCGAAGAAGTTCTGCCTAGCGCGGCACATGCATTCGGCCCCGAACCATCTGTCGCGGCTGATCGTTGATGCAGCGGCTAATGCAGACCGCACAGGGGAGGAGCACGATGCGCCGGAAGAAGCAGCGGCGGAATCGGGTCCACCCGAGGCAGCCGTATCGGATCCACGCGTGAAGGAAGCGCTACAGTTGCACCGGTCGGTGGAAGCGAAAGGGCTGCGAAAGGTCGGCCATCTCGTCTGGTACCACTGCTGCTTTCCCAAGTGTCCGGAGACGTTCACGAGCGAAGCGGCCCTGCTGGAGCACGCCCAGGCCGAGCACTACGGGCAGCGGCGGGAAAACCAAAACGAGCGCCAGCAGGACACGAACGTGTGTCCCACCTGCTGCAAACCGTTCCAAACGCTGGCGAAACTGTACTGGCATCGGGTGAAACGGTTCGTGCCGCGCGAGTATAAGTGCAAACAGTGCGCCAGCACCTTCGACCGGTGGGTGCAGCTGAAGATCCACGTGGAGCAGGAGCACAGCGCCACGCCGCCCAGCTTCGAGTGTGCCGAGTGCGGCAAATCGTTCGTGCTCCGGGCGAGACTGGTCGCCCACCAGAAGACGCACACCGACCGGAAGGACCACAAGTGCGACGTGTGCGGGTGTGCGTTCGTCAGCAAGGGGCTGCTGAAGCGGCACCGGCGTGCGCTCCACGCCGCCGAGCTGCTGTTTGAGTGTAAGCTGTGCTCGAAAAAATTTGCCGTGGTGGAGAAGCTGAAAATTCACCAGCGCGTCCACACGGGCGAACGCCCTTACGAGTGTACGTTCTGCTCGCGCACCTTCATACACTTTTCCGACCGGAAGCGGCACGAGATGGCAGCGCACACGATGGAACGCCCGTACAAGTGCAAGCTCTGCCCGGCGTCGTACATTCGCAACCGCGAGCTGAATCTGCACATGCAAAAGCACCAGTCGGATGGAAAGGGGAAAACCCTCGTTAAAAGTAGGGGGGAAACTTGA
Protein Sequence: MLRRPSKRRKVSNVNEEETEFTPASVEQKCCICSKHPKGDLLELSTVVESGSSLTIATVVEQVASIKVNNVQKSICGGCWTKIQAAYSIQKEIRGSECMAQQDVECYSETEEENAENANCTEQDDPDPLVVDGIDESEYCIEYLEEQEEEQQPPAKEEAADIEIEACCSDEEEHEELRADGGKVTRQFQMPNEATIVADVLHEQYRMVEVTGERCCGCSFVARSRKELLQHSETVHSVEMTDHGDYCPICFYKFSTDQQLERHIDEFKLNKMYVCLRCNRFYNVKRKLFNHLIGCGGMVEEVDVQASGTNNDDALTIEALKEEDGEEAEGLEEDSQYEECYLQEGTDTDEQQELHPEDRLQNATDPRVMHRYKALFEEVLSNEELYCQLSEKELNVQDVQIAEQHVFETFKYIRLRGLRCCGCSYTCMSKALLIEHSNLAHPPEDPSQHVDEHACELCRAEFQNTLNLVKHICFFTTRQLFLCTVCDVSFLNKESLRNHQRHNERHRELENYKFEQAGIELDTAEGFVELDQPAVADELRKLVVEKNSYRPKAVTCIPMPDERFIRRRKEYNNYSVLVVAGEYCCGCGKFFDTTSELQQHAEQEHYLPLNYCARTYGHQCEICYAVFELERGFAVHRSMSRSKPKTLYLCKLCGLLFSKKFCLARHMHSAPNHLSRLIVDAAANADRTGEEHDAPEEAAAESGPPEAAVSDPRVKEALQLHRSVEAKGLRKVGHLVWYHCCFPKCPETFTSEAALLEHAQAEHYGQRRENQNERQQDTNVCPTCCKPFQTLAKLYWHRVKRFVPREYKCKQCASTFDRWVQLKIHVEQEHSATPPSFECAECGKSFVLRARLVAHQKTHTDRKDHKCDVCGCAFVSKGLLKRHRRALHAAELLFECKLCSKKFAVVEKLKIHQRVHTGERPYECTFCSRTFIHFSDRKRHEMAAHTMERPYKCKLCPASYIRNRELNLHMQKHQSDGKGKTLVKSRGET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101169;
90% Identity: iTF_00102565; iTF_00095846; iTF_00101169;
80% Identity: -