Basic Information

Insect: Anopheles coluzzii
Gene Symbol: -
Assembly: GCA_016097175.1
Location: CM027930.1:32752452-32755517[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.6 82 3.6 1.6 2 23 216 238 216 238 0.94

2 17 0.0015 0.078 13.2 0.1 2 20 248 266 247 268 0.94

3 17 0.082 4.3 7.7 0.8 1 20 275 294 275 296 0.95

4 17 0.8 42 4.6 2.2 2 23 421 443 420 443 0.92

5 17 0.85 44 4.5 1.7 1 21 455 475 455 476 0.94

6 17 0.011 0.57 10.4 1.6 1 21 483 503 483 508 0.92

7 17 0.0021 0.11 12.7 1.2 3 23 586 607 585 607 0.90

8 17 1.5 80 3.7 0.1 1 20 620 639 620 641 0.87

9 17 0.019 1 9.6 2.8 1 21 650 670 650 675 0.92

10 17 0.029 1.5 9.1 0.7 2 23 741 765 740 765 0.84

11 17 2.8 1.5e+02 2.8 0.6 2 20 782 800 782 802 0.92

12 17 0.0014 0.074 13.2 0.3 1 23 809 832 809 832 0.94

13 17 2.4e-05 0.0013 18.8 0.1 1 23 839 861 839 861 0.98

14 17 2e-05 0.001 19.1 2.4 1 23 867 890 867 890 0.96

15 17 0.00011 0.006 16.7 0.6 1 23 896 918 896 918 0.98

16 17 0.008 0.42 10.9 2.5 1 23 924 947 924 947 0.93

17 17 2.2e-05 0.0011 18.9 0.6 1 23 953 975 953 975 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.6	82	3.6	1.6	2	23	216	238	216	238	0.94
2	17	0.0015	0.078	13.2	0.1	2	20	248	266	247	268	0.94
3	17	0.082	4.3	7.7	0.8	1	20	275	294	275	296	0.95
4	17	0.8	42	4.6	2.2	2	23	421	443	420	443	0.92
5	17	0.85	44	4.5	1.7	1	21	455	475	455	476	0.94
6	17	0.011	0.57	10.4	1.6	1	21	483	503	483	508	0.92
7	17	0.0021	0.11	12.7	1.2	3	23	586	607	585	607	0.90
8	17	1.5	80	3.7	0.1	1	20	620	639	620	641	0.87
9	17	0.019	1	9.6	2.8	1	21	650	670	650	675	0.92
10	17	0.029	1.5	9.1	0.7	2	23	741	765	740	765	0.84
11	17	2.8	1.5e+02	2.8	0.6	2	20	782	800	782	802	0.92
12	17	0.0014	0.074	13.2	0.3	1	23	809	832	809	832	0.94
13	17	2.4e-05	0.0013	18.8	0.1	1	23	839	861	839	861	0.98
14	17	2e-05	0.001	19.1	2.4	1	23	867	890	867	890	0.96
15	17	0.00011	0.006	16.7	0.6	1	23	896	918	896	918	0.98
16	17	0.008	0.42	10.9	2.5	1	23	924	947	924	947	0.93
17	17	2.2e-05	0.0011	18.9	0.6	1	23	953	975	953	975	0.99

Sequence Information

Coding Sequence: ATGCTGCGAAGACCGTCGAAGCGACGAAAAGTGTCCAACGTGGAGGAAGAAGAAACGGAATTCACGCCAGCGTCTGTTGAGCAGAAATGCTGCATCTGCTCCAAACATCCGAAGGGCGATTTGCTTGAACTTTCCACGGTTGTAGAATCGGGCAGCTCCCTCACCATTGCCACCGTTGTCGAACAGGTGGCCTCCATCAAGGTAAACAATGTCCAGAAGAGCATTTGCGGTGGTTGTTGGACCAAAATTCAGGCGGCCTACTCGATACAGAAGGAAATCCGCGGATCAGAATGTATGGCACAGCAGGATGTCGAGTGCTACAGCGAGACTGAGGAAGAGGAAGAGAACGCGGAAAATGCCAACCGTCCCGAAAAGGACGATCCGGACCCGCTCGTCGTAGATGGCATTGACGAGAGCGAATATTGCATCGAATATCTGGAGGAACAGGAGGAAGAGCAGCAACCACCAGCAAAGGAAGAAGCCGCAGACATTGAGATTGAAGCATGCTGCTCCGACGAGGAAGAGCACGAAGAGCTCCGAGCGGACGGTGGTAAGGTGACGCGTCAGTTCCAAATGCCAAATGAGGCCACGATTGTGGCCGACGTGCTGCACGAGCAGTATCGGATGGTGGAGGTCACCGGGGAACGGTGCTGCGGGTGCAGCTTTGTCGCACGATCACGCAAAGAGCTGCTGCAACACTCGGAAACGGTCCACTCGGTAGAGATGACCGACCACGGCGACTACTGTCCGATTTGTTTCTACAAATTCTCCACCGATCAGCAGCTCGAGCGCCACATCGATGAGTTTAAGCTGAACAAGATGTACGTGTGTTTGCGCTGCAATCGGTTCTACAACGTGAAGCGGAAGCTGTTTAACCACCTGCTCGAATGTGGTGGCATGGTTGAGGAGGTGGAAGTGCAGGCAAGCGGAACGAACAATGATGATGCACTTACGATCGAAGCCCTGAAAGAGGAGGACGGGGACGAGGAGGAAGGGCTGGAGGAAGATAGTCAGTATGAGGAGTGTTATCTGCAGGAAGGCACAGACACGGACGAACAGCAAGAGCTGCACGCAGAGGACCGCCTACAGAACGCAACCGATCCACGTGTGATGCATCGCTACAAAGCGCTGTTCGAAGAGGTGCTGTCGAACGAAGAGCTTTACTGCCAGCTGAGCGAGAAGGAACTGAACGTGCAGGATGTGCAGATCGCGGAGCAGCACGTGTTCGAAACGTTCAAGTACATTCGGTTGCGGGGATTGCGCTGTTGCGGGTGCTCCTACACCTGCATGTCCAAGGCGCTGCTGATTGAGCACAGCAATCTGGCTCATCCGCCCGAAAATCCGCCGGAGCACGTTGATGAGCATTCGTGCGAGCTATGCCGGGCGGAGTTTCAAAACACGCTGAATCTCGTGAAGCATATCTGCTTCTTCACCACCCGGCAGCTGTTCCTGTGCACGGTGTGTGACGTATCGTTTCTGAACAAGGAAAGCTTGCGGAACCACCAGCGCCACAACGAACGGCACCGCGAGCTGGAGAACTACAAGTTTGAGCAGGCCGGCATCGAGCTCGACACAGCGGAAGGGTTCGTCGAACTCGACCAGCCGGCCGTGGCCGACGAGCTGCGGAAGCTGGTGGTGGAAAAGATTAGCTACCGGCCGAAAGCGGTCACCTGCATTCCCATGCCGGACGAACGGTTCATCCGGCGGAGGAAGGAGTACAACAACTACAGCGTCCTGGTCGTGGCTGGCGAGTATTGCTGCGGGTGTGGCAGGTTCTTCGATACGACTTCCGAGCTGCAGCAGCACGCCGAGCAGGAGCACTATTTGCCGCTCAACTTTTGTGCCCGCACGTACGGCCACCAGTGCGAGATCTGTTACGCCGTGTTTGAGCTCGAGCGAGGCTTCGCGGTGCACCGGTCGATGAGTCGCTCCAAGCAAAAGACGCTATACCTCTGCAAACTCTGTGGGCTGCTGTTTTCGAAGAAGTTCTGCCTAGCGCGGCACATGCATTCTGCCCCGAACCACCTGTCGCGGCTGATCGTTGATGCAGCGGCTAATGCAGACCGCACAGGGGAGGAGCACGATGCGCCGGAGGAAGCAGACGCGGAACCGGGTCCACCCGAGGCAGCCGTATCGGATCCACGCGTGAAGGAAGCGCTACAGTTGCACCGGTCGGTGGAAGCGAAAGGGCTGCGAAAGGTCGGCCATCTCGTCTGGTACCACTGCTGCTTTCCCAAGTGTCCGGAGACGTTCACGAGCGAAGCGGCCCTGCTGGAGCACGCCCAGGCCGAGCACTACGGGCAGCGGCGGGAAAACCAAAACGAGCGCCAGCAGGACACGAACGTGTGTCCCACCTGCTGCAAACCATTCCAAACGCTGGCGAAACTGTACTGGCATCGGGTGAAACGGTTCGTGCCGCGCGAGTATAAGTGCAAGCAGTGCGCCAGCACCTTCGACCGGTGGGTGCAGCTGAAGATTCACGTGGAGCAGGAGCACAGCGCCACGCCGCCCAGCTTCGAGTGTGCCGAGTGCGGCAAATCGTTCGTGCTGCGGGCGAGACTGGTCGCCCACCAGAAGACGCACACCGACCGGAAGGACCACAAGTGCGACGTGTGCGGGTGTGCGTTCGTCAGCAAGGGGCTGCTGAAGCGGCACCGGCGAGCGCTCCACGCCACCGAGCTGCTGTTTGAGTGTAAGCTGTGCTCGAAAAAGTTTGCCGTGGTGGAAAAGCTGAAAATTCACCAGCGCGTCCACACGGGCGAACGCCCCTACGAGTGTACGTTCTGCTCGCGCACCTTCATACACTTCTCCGACCGGAAGCGGCACGAGATGGCAGCGCACACGATGGAACGCCCGTACAAGTGCACGCTCTGCCCGGCATCGTACATTCGCAACCGCGAGCTGAATCTGCACATGCAAAAGCACCAGTCGGATGGAAAGGGAAAAACCTCGTTAAAAGTAGGGGGGAAACTTGAACTGAGCATGGCGAAGGAAATCATTTGA
Protein Sequence: MLRRPSKRRKVSNVEEEETEFTPASVEQKCCICSKHPKGDLLELSTVVESGSSLTIATVVEQVASIKVNNVQKSICGGCWTKIQAAYSIQKEIRGSECMAQQDVECYSETEEEEENAENANRPEKDDPDPLVVDGIDESEYCIEYLEEQEEEQQPPAKEEAADIEIEACCSDEEEHEELRADGGKVTRQFQMPNEATIVADVLHEQYRMVEVTGERCCGCSFVARSRKELLQHSETVHSVEMTDHGDYCPICFYKFSTDQQLERHIDEFKLNKMYVCLRCNRFYNVKRKLFNHLLECGGMVEEVEVQASGTNNDDALTIEALKEEDGDEEEGLEEDSQYEECYLQEGTDTDEQQELHAEDRLQNATDPRVMHRYKALFEEVLSNEELYCQLSEKELNVQDVQIAEQHVFETFKYIRLRGLRCCGCSYTCMSKALLIEHSNLAHPPENPPEHVDEHSCELCRAEFQNTLNLVKHICFFTTRQLFLCTVCDVSFLNKESLRNHQRHNERHRELENYKFEQAGIELDTAEGFVELDQPAVADELRKLVVEKISYRPKAVTCIPMPDERFIRRRKEYNNYSVLVVAGEYCCGCGRFFDTTSELQQHAEQEHYLPLNFCARTYGHQCEICYAVFELERGFAVHRSMSRSKQKTLYLCKLCGLLFSKKFCLARHMHSAPNHLSRLIVDAAANADRTGEEHDAPEEADAEPGPPEAAVSDPRVKEALQLHRSVEAKGLRKVGHLVWYHCCFPKCPETFTSEAALLEHAQAEHYGQRRENQNERQQDTNVCPTCCKPFQTLAKLYWHRVKRFVPREYKCKQCASTFDRWVQLKIHVEQEHSATPPSFECAECGKSFVLRARLVAHQKTHTDRKDHKCDVCGCAFVSKGLLKRHRRALHATELLFECKLCSKKFAVVEKLKIHQRVHTGERPYECTFCSRTFIHFSDRKRHEMAAHTMERPYKCTLCPASYIRNRELNLHMQKHQSDGKGKTSLKVGGKLELSMAKEII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00101169;
90% Identity: iTF_00107190;
80% Identity: -