Basic Information

Insect: Anopheles quadriannulatus
Gene Symbol: -
Assembly: GCA_000349065.1
Location: KB665954.1:1123223-1127275[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.021 1 9.4 0.3 2 23 254 275 253 275 0.96

2 17 9.8e-05 0.0048 16.8 4.0 1 23 306 329 306 329 0.97

3 17 0.032 1.6 8.8 0.4 3 23 336 356 334 356 0.94

4 17 6e-05 0.0029 17.4 2.2 1 23 360 382 360 382 0.97

5 17 0.014 0.7 9.9 0.1 2 23 393 415 392 415 0.95

6 17 0.0022 0.11 12.5 1.7 2 20 422 440 421 442 0.94

7 17 1.2e-07 5.7e-06 25.9 1.3 1 23 451 473 451 473 0.98

8 17 0.0044 0.22 11.5 5.1 1 23 479 502 479 502 0.96

9 17 5 2.5e+02 1.9 0.4 9 23 717 732 699 732 0.76

10 17 0.0012 0.058 13.3 0.1 2 23 740 761 739 761 0.97

11 17 0.03 1.5 8.9 0.7 1 23 767 787 767 787 0.89

12 17 0.0015 0.075 13.0 1.4 1 23 792 815 792 815 0.97

13 17 0.00067 0.033 14.1 0.5 2 23 821 842 820 842 0.96

14 17 0.00097 0.047 13.6 5.4 1 23 846 868 846 868 0.97

15 17 0.38 18 5.5 0.2 2 23 879 901 878 901 0.94

16 17 5.2e-05 0.0025 17.6 1.3 3 20 909 926 908 928 0.94

17 17 4.1e-05 0.002 17.9 1.0 1 21 937 957 937 958 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.021	1	9.4	0.3	2	23	254	275	253	275	0.96
2	17	9.8e-05	0.0048	16.8	4.0	1	23	306	329	306	329	0.97
3	17	0.032	1.6	8.8	0.4	3	23	336	356	334	356	0.94
4	17	6e-05	0.0029	17.4	2.2	1	23	360	382	360	382	0.97
5	17	0.014	0.7	9.9	0.1	2	23	393	415	392	415	0.95
6	17	0.0022	0.11	12.5	1.7	2	20	422	440	421	442	0.94
7	17	1.2e-07	5.7e-06	25.9	1.3	1	23	451	473	451	473	0.98
8	17	0.0044	0.22	11.5	5.1	1	23	479	502	479	502	0.96
9	17	5	2.5e+02	1.9	0.4	9	23	717	732	699	732	0.76
10	17	0.0012	0.058	13.3	0.1	2	23	740	761	739	761	0.97
11	17	0.03	1.5	8.9	0.7	1	23	767	787	767	787	0.89
12	17	0.0015	0.075	13.0	1.4	1	23	792	815	792	815	0.97
13	17	0.00067	0.033	14.1	0.5	2	23	821	842	820	842	0.96
14	17	0.00097	0.047	13.6	5.4	1	23	846	868	846	868	0.97
15	17	0.38	18	5.5	0.2	2	23	879	901	878	901	0.94
16	17	5.2e-05	0.0025	17.6	1.3	3	20	909	926	908	928	0.94
17	17	4.1e-05	0.002	17.9	1.0	1	21	937	957	937	958	0.94

Sequence Information

Coding Sequence: ATGGCCTCGGTCACAAGATGCGAAGTTTGCTTCTCCACAGCGGACAGCGATCGGAAGGCAATTTTCGCAGAGGAAAATAGGCATATTGTTGGGATCGTAGCGAAACATTTGGGGTTTGAGATTACACCGACAGTGGAAGATGCCTCGATTTGCAGCAAATGCTGGAGTGCGTTGTATGAGTTTCACAAATATTACTGTGAAATAGAGGCAGCCAGGCAGCAGCATGAGCATGAGCTACTGGCAATTGGCGACAAACAGCAGGAAGAGGTCACTGTCGATTGCGACAGCTTAGAGCCGAGCTATAGGACTGAATTTTTCGAGGTGAAGGTAGAACCATTCGAACAGACGGACGTGTTTGAGCAGGAAAATTCCAACTGTTCCGACGAGAAGCCGCTGCACTGTGCGTTCGTAAAATGTGAAGAACCACCGATCGATCTCGATCCAACCGCCCCGTCCTCGGATGAGGACTCTGCAGTGCCGCAGGGCAGCAGGTCAGACTCGTCCTCGCCGGATAGGAGGAAGCCGAAGCGGGAGAGGAACCCGAAACGGCCTCCAACGAGCGACACTGAGACGAAGCAAAGTAAAGCGACCGCCCAGAAGGAGGAGGATGAAAGTTTGCACAACTTCTACAAACGGATCGTGTGCGAGGTGTGCGACATTCAGCGCATGCTGGTGGGTGAACCGCAGATCGACTTCGGCACCTGGCGAGCGCTGCTGCGCCACACGAAGGAGGTGCACAAGCACGACAAGGTGTACGTAAAGTGTCCGGTGTGCGAGATGAAGATGCGCACGAAGCAAACGCTGCTGCAGCACATGGATTGGCACGAAAATCCAGAAAAGTATCGGTGCGAACTGTGCGGCGAGAAGCACCAGAACATGAAGGAACACATCCAGAACAAGCACCAGGAGCGGCAGTTTTGTTGTGACGTTTGTGGGAAAAAGTTCCCGTTCAAGAAGAGACTTACAGTGCATATGAAAAAGATGCACGTGGAGAAGGACATCATTTGTGACCAGTGTCAGAAGCCCTTCACAAAGTACACGATAGAAGATCACAAACGGTCCGTCCATTCGGCGCGGTTTGTCTGTGAACACTGTCCGAAAACGTTCAACAGTCGCTTCCGGTTGCTGCAGCACATGGAGGAGCACGATGAAAGCTTGCGCAACTCCACCTCCGTACCGTGCACGATCTGCGGTCAGGTGATGCGCGACAAGTATATCCTTACCCGACACATCAAGCTGATGCACACGGTCCAGCCGGCGGTCAGCTGCGAAACGTGTGGGAAAACGTTCAAATGCAAGCGCAACCTGTCGGTGCACATGACGAACGTGTGCATGGAACCGACCCGCCTCTACCCGTGCACCATCTGTGGGAAGGAGTTTCGGCGCAAGAACAAGCTGAAGGAGCACATGTCGACGCACACGGGCAAACCGTTGTACATGTGCTCCTTCTGTCCGGAAACATTCCGCCAGGATACGCATCTGTATCATCATCGGAAGAATGCGCACTACGAGCGATGGTTGGAGATGCAGCAGCAGCGCAAGGAGGGTGTCACTCCCACGGACGAATGCCAATGGATCTGCCGGACCTGTTGGACAAGCTTGGACTCGTTCCACAGCTTCTACGTCAGCATTGAGCAGCGGCACGAACGGCACACGGACAAGCTGCGTGTGGACATTATCGTCGACAGTGAGCAAGCAGCGAGCCCGTCCCCTGCCAGTCCGACGTACAATACGGAGTTTCTGGAGATAAAGGGCGAACCGCTGGACGGCGACGACGAGCTGGAGGACATGGACGACGAGGAGGAGGAGGAGGAGGAGTTCGATCTAACGGAAGATGGCGATGGCAGTTGCGGAGGAAGTGACAAAATGCTACCGAACGAGGAGATCAAGAGCGAAAGTGATTCGGATAGAGAAGGAGGAAGCGTATCGTCCCGTGCGGATGAGGGCAGGAAAAGGCAACGACCGTCCCGATCCCGCAATGCATCCCGCGCTCCCAAGCGCGATGCCGAAGAGCAGCTGGCGAAACGGAAGGCCGGCGGTCGGTTTCCTGCCGATCCGGAGGAGGACAAGAACATCCTGCAGTTCTACAAGCGCATCGTGTGCGAGGTGTGCGACAACAAGCGGATGATGGTGGGCGAGCCGCTGATAGAGTACGCGACGTGGGGTGAGCTGTTGCGGCACACGAAGGAACTGCACGGCCATTACAAAATCTTCGTCCAGTGTCCGGTGTGCGAGATGAAGCTGCGCACGAAGGTAACGCTGGTGCAGCACATGGACATGCACCAGAACCCGGACAAATATCGGTGCGAGGTGTGCGGCGAGGTGTTCCAGAACATGAAGGAGCACATGCAGAACAAGCACGAGGAGCGACAGTTTAGCTGCGATCAGTGCGGCAGCAAGTTCCCGTTCAAGAAGCGGCTCGTGGTGCACATGAAGAAAATGCACGGCGAAAAGGATGTCACGTGCGAGCAGTGCGGAAAATCCTTCACAAAGTACACGATCGAGGATCATCGGCGTTCGGTGCACATGGACCGGTTCGTGTGTGAGCATTGTCCGAAAACGTTCAAAATTCGGTTCCGCCTGCACAAGCACATGCAGGAGCACGACAAAAGCCTGCGCATCTCGACCTCCGTTCCGTGTCCGACCTGCGGGCAGGTGATGGGCGACAAGTACATCCTCCGCCAGCACATCAAGCATATGCACGTCGAGCAGCAGGCGGTGGATTGTGAGACGTGCGGGAAAACGTTTAAGAACCATCGCAACCTCAAGATACACCTCACGAACGTGTGCATGAAGCCGGTGCAGCTGCATCCGTGCGCAATCTGTGGCAAGCAGTTTCGGCACAAGAACAAGCTGAAGGACCATATGGCGTCCTGCACGCCGAATTGA
Protein Sequence: MASVTRCEVCFSTADSDRKAIFAEENRHIVGIVAKHLGFEITPTVEDASICSKCWSALYEFHKYYCEIEAARQQHEHELLAIGDKQQEEVTVDCDSLEPSYRTEFFEVKVEPFEQTDVFEQENSNCSDEKPLHCAFVKCEEPPIDLDPTAPSSDEDSAVPQGSRSDSSSPDRRKPKRERNPKRPPTSDTETKQSKATAQKEEDESLHNFYKRIVCEVCDIQRMLVGEPQIDFGTWRALLRHTKEVHKHDKVYVKCPVCEMKMRTKQTLLQHMDWHENPEKYRCELCGEKHQNMKEHIQNKHQERQFCCDVCGKKFPFKKRLTVHMKKMHVEKDIICDQCQKPFTKYTIEDHKRSVHSARFVCEHCPKTFNSRFRLLQHMEEHDESLRNSTSVPCTICGQVMRDKYILTRHIKLMHTVQPAVSCETCGKTFKCKRNLSVHMTNVCMEPTRLYPCTICGKEFRRKNKLKEHMSTHTGKPLYMCSFCPETFRQDTHLYHHRKNAHYERWLEMQQQRKEGVTPTDECQWICRTCWTSLDSFHSFYVSIEQRHERHTDKLRVDIIVDSEQAASPSPASPTYNTEFLEIKGEPLDGDDELEDMDDEEEEEEEFDLTEDGDGSCGGSDKMLPNEEIKSESDSDREGGSVSSRADEGRKRQRPSRSRNASRAPKRDAEEQLAKRKAGGRFPADPEEDKNILQFYKRIVCEVCDNKRMMVGEPLIEYATWGELLRHTKELHGHYKIFVQCPVCEMKLRTKVTLVQHMDMHQNPDKYRCEVCGEVFQNMKEHMQNKHEERQFSCDQCGSKFPFKKRLVVHMKKMHGEKDVTCEQCGKSFTKYTIEDHRRSVHMDRFVCEHCPKTFKIRFRLHKHMQEHDKSLRISTSVPCPTCGQVMGDKYILRQHIKHMHVEQQAVDCETCGKTFKNHRNLKIHLTNVCMKPVQLHPCAICGKQFRHKNKLKDHMASCTPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104554; iTF_00101133;
90% Identity: iTF_00104554;
80% Identity: -