Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: AXCO02002901.1:3489-7550[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.024 1.3 9.4 0.3 2 23 256 277 255 277 0.96

2 17 0.00011 0.0062 16.8 3.9 1 23 308 331 308 331 0.97

3 17 0.038 2 8.8 0.4 3 23 338 358 336 358 0.94

4 17 7e-05 0.0038 17.4 2.2 1 23 362 384 362 384 0.97

5 17 0.016 0.88 10.0 0.1 2 23 395 417 394 417 0.95

6 17 0.0026 0.14 12.5 1.7 2 20 424 442 423 444 0.94

7 17 1.4e-07 7.4e-06 25.9 1.3 1 23 453 475 453 475 0.98

8 17 0.0052 0.28 11.5 5.1 1 23 481 504 481 504 0.96

9 17 5.9 3.2e+02 1.9 0.4 9 23 717 732 699 732 0.76

10 17 0.0014 0.075 13.3 0.1 2 23 740 761 739 761 0.97

11 17 0.035 1.9 8.9 0.7 1 23 767 787 767 787 0.89

12 17 0.0018 0.097 13.0 1.4 1 23 792 815 792 815 0.97

13 17 0.00078 0.042 14.1 0.5 2 23 821 842 820 842 0.96

14 17 0.0011 0.061 13.6 5.4 1 23 846 868 846 868 0.97

15 17 0.44 24 5.5 0.2 2 23 879 901 878 901 0.94

16 17 6.1e-05 0.0033 17.6 1.3 3 20 909 926 908 928 0.94

17 17 4.9e-05 0.0026 17.9 1.0 1 21 937 957 937 958 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.024	1.3	9.4	0.3	2	23	256	277	255	277	0.96
2	17	0.00011	0.0062	16.8	3.9	1	23	308	331	308	331	0.97
3	17	0.038	2	8.8	0.4	3	23	338	358	336	358	0.94
4	17	7e-05	0.0038	17.4	2.2	1	23	362	384	362	384	0.97
5	17	0.016	0.88	10.0	0.1	2	23	395	417	394	417	0.95
6	17	0.0026	0.14	12.5	1.7	2	20	424	442	423	444	0.94
7	17	1.4e-07	7.4e-06	25.9	1.3	1	23	453	475	453	475	0.98
8	17	0.0052	0.28	11.5	5.1	1	23	481	504	481	504	0.96
9	17	5.9	3.2e+02	1.9	0.4	9	23	717	732	699	732	0.76
10	17	0.0014	0.075	13.3	0.1	2	23	740	761	739	761	0.97
11	17	0.035	1.9	8.9	0.7	1	23	767	787	767	787	0.89
12	17	0.0018	0.097	13.0	1.4	1	23	792	815	792	815	0.97
13	17	0.00078	0.042	14.1	0.5	2	23	821	842	820	842	0.96
14	17	0.0011	0.061	13.6	5.4	1	23	846	868	846	868	0.97
15	17	0.44	24	5.5	0.2	2	23	879	901	878	901	0.94
16	17	6.1e-05	0.0033	17.6	1.3	3	20	909	926	908	928	0.94
17	17	4.9e-05	0.0026	17.9	1.0	1	21	937	957	937	958	0.94

Sequence Information

Coding Sequence: ATGGCCTCGGTCACAAGATGCGAAGTTTGCTTCTCCACAGCGGACAGCGATCGAAAGGCAATTTTCGCAGAGGAAAACAGCCATATTGTTGGGATCGTAGCGAAACATTTGGGGTTTGAGATTACGCCGGCAGTGGAAGATGCCTCGATGTGCAGCAAATGCTGGAGTGCGTTGCAAGAATTTCACAAGTATTACTGTGAAATAGAGGCAGCCAGGCAACAGCATGAGCATGAGCATGAGCTACTGGCAATTGGCGACAAACAGCAGGAAGAGGTCACTGTCGTTTGCGACAGCTTAGAGCCGAGCTATAGGACGGAATTTTTCGAGGTGAAAGTAGAACCATTCGAACAGACAGACGTGTTTGAGCTGGAAAATTCCAACGGTTCCGATGAGAAGCCGCTGCACTGTGCGTTCGTAAAATGTGAAGAACCGCCGATCGATCTTGATCCGACCGCCCCGTCCTCAGATGAGGACTCTGCAGTGCCGCAGGGCAGCAGGTCAGACTCGTCCTCACCGGATAGGAGGAAGCCGAAGCGGAAGAGGAACCCGAAACGGTCACAAACGAGCGACACCGAGACGAAGCAAAGTAAAGCGACCGCCCAGAAGGAGGAGGATGAAAGTTTGCACAACTTCTACAAACGGATCGTGTGCGAGGTGTGTGACATTCAGCGCATGCTGGTGGGTGAACCGCAGATCGACTTCGGCACCTGGCGAGCGCTGCTGCGCCACACGAAGGAGGTACACAACCACGACAAGGTGTACGTAAAGTGTCCGGTGTGCGAGATGAAGATGCGCACGAAGCAAACGCTGCTGCAGCACATGGATTGGCACGAAAATCCGGAAAAGTATCGGTGCGAACTGTGCGGCGAGAAGCACCAGAACATGAAGGAGCACATCCAGAACAAGCACCAGGAGCGGCAGTTTTGTTGTGACGTTTGTGGGAAAAAGTTCCCGTTCAAGAAGAGACTTAACGTGCATATGAAAAAGATGCACGTGGAAAAAGACATCATTTGTGATCAGTGTCAGAAGCCCTTCACAAAGTACACGATAGAAGATCACAAGCGGTCCGTCCATTCGGCGCGGTTTGTCTGTGAACACTGTCCGAAAACGTTCAACAGTCGCTTCCGGTTGCTGCAGCACATGGAGGAGCACGATGAAAGCTTGCGCAACTCCACCTCCGTACCGTGCACGATCTGCGGTCAGGTGATGCGCGACAAGTACATCCTGACCAGACACATCAAGCAGATGCACACGGTCCAGCCGGCGGTCAGCTGCGAAACGTGTGGGAAAACGTTCAAATGCAAGCGCAACCTGTCGGTGCACATGACGAACGTGTGCATGGAACCGACCCGCCTCTACCCGTGCACCATCTGTGGGAAGGAGTTTCGGCGCAAGAACAAGCTGAAGGAGCACATGTCGACGCACACGGGTAAACCGTTGTACATGTGCTCCTTCTGTCCGGAAACATTCCGCCAGGATACGCATCTGTACCACCATCGGAAGAATGCACACTACGAGCGATGGTTGGAGATGCAGCAGCAGCGCAAGGAGGGTGTCACTCCCACGGACGAATGCCAATGGATCTGCCGGAGCTGTTGGACAAGCTTGGACTCGTTTCACAGCTTCTACGTCAGCATTGAGCAGCGGCACGAACGGCACACGGACAAGCTGCGTGTGGACAGTATCGTCGACAGTGAGCAAGCGGCGAGCCCGTCCCCTGCCAGTCCGACGTACAATACGGAGTTTCTGGAGATAAAGGGCGAACCGCTGGACGGCGACGACGAGCTGGAGGACCTAGAGGACGAGGAGGAGGAGGAGTTCGATCTAACGGAAGATGGCGATGGCAGTTGCGGTGGAAGTGAGAAAATGCTACCGAGCGAGGAGATCAAGAGCGAAAGTGATTCGGATGGAGAAGGAGGAAGCGTATCGTCCCGTGCGGATGAGGGCAGGAAAATGCAACGACCGTCCCGATCCCGCAATACGTCCCGTGCTCCCAAACGCGATGCCGAAGAGCAGCTGGCGAAACGGAAGGCCGGCGGTCGGTTTCCTGCCGATCCGGAGGAGGACAAGAACATCCTGCAGTTCTACAAGCGCATCGTGTGCGAGGTGTGCGACAACAAGCGGATGATGGTGGGCGAACCGCTGATAGAGTACGCGACGTGGGGTGAGCTGCTGCGGCACACGAAGGAACTGCACGGCCATTACAAAATCTTCGTCCAGTGTCCGGTGTGCGAGATGAAGCTGCGCACGAAGGTGACGCTGGTGCAGCACATGGACATGCACCAGAACCCGGACAAGTATCGGTGCGAGGTGTGCGGCGAGGTGTTCCAGAACATGAAGGAGCACATGCAGAACAAGCACGAGGAGCGACAGTTTAGCTGCGATCAGTGCGGCAGCAAGTTCCCGTTCAAGAAGCGGCTCGTGGTGCACATGAAGAAAATGCACGGCGAAAAGGATGTCACGTGCGAGCAGTGCGGAAAATCCTTCACAAAGTACACGATCGAGGATCATCGGCGTTCGGTGCACATGGACCGGTTTGTGTGTGAGCATTGCCCGAAAACGTTCAAAATTCGGTTCCGCCTGCACAAGCACATGCAGGAGCACGACAAAAGCCTGCGCATCTCGACCTCCGTGCCGTGTCCGACCTGTGGGCAGGTGATGGGCGACAAGTACATCCTCCGCCAGCACATCAAGCATATGCACGTCGAGCAGCAGGCGGTGGATTGTGAGACGTGCGGGAAAACGTTTAAAAACCATCGCAACCTCAAGATACACCTCACGAACGTGTGCATGAAGCCGGTGCAGCTGCATCCATGCGCAATCTGTGGCAAGCAGTTTCGGCACAAGAACAAGCTGAAGGACCATATGGCGTCCTGCACGCCGAATTGA
Protein Sequence: MASVTRCEVCFSTADSDRKAIFAEENSHIVGIVAKHLGFEITPAVEDASMCSKCWSALQEFHKYYCEIEAARQQHEHEHELLAIGDKQQEEVTVVCDSLEPSYRTEFFEVKVEPFEQTDVFELENSNGSDEKPLHCAFVKCEEPPIDLDPTAPSSDEDSAVPQGSRSDSSSPDRRKPKRKRNPKRSQTSDTETKQSKATAQKEEDESLHNFYKRIVCEVCDIQRMLVGEPQIDFGTWRALLRHTKEVHNHDKVYVKCPVCEMKMRTKQTLLQHMDWHENPEKYRCELCGEKHQNMKEHIQNKHQERQFCCDVCGKKFPFKKRLNVHMKKMHVEKDIICDQCQKPFTKYTIEDHKRSVHSARFVCEHCPKTFNSRFRLLQHMEEHDESLRNSTSVPCTICGQVMRDKYILTRHIKQMHTVQPAVSCETCGKTFKCKRNLSVHMTNVCMEPTRLYPCTICGKEFRRKNKLKEHMSTHTGKPLYMCSFCPETFRQDTHLYHHRKNAHYERWLEMQQQRKEGVTPTDECQWICRSCWTSLDSFHSFYVSIEQRHERHTDKLRVDSIVDSEQAASPSPASPTYNTEFLEIKGEPLDGDDELEDLEDEEEEEFDLTEDGDGSCGGSEKMLPSEEIKSESDSDGEGGSVSSRADEGRKMQRPSRSRNTSRAPKRDAEEQLAKRKAGGRFPADPEEDKNILQFYKRIVCEVCDNKRMMVGEPLIEYATWGELLRHTKELHGHYKIFVQCPVCEMKLRTKVTLVQHMDMHQNPDKYRCEVCGEVFQNMKEHMQNKHEERQFSCDQCGSKFPFKKRLVVHMKKMHGEKDVTCEQCGKSFTKYTIEDHRRSVHMDRFVCEHCPKTFKIRFRLHKHMQEHDKSLRISTSVPCPTCGQVMGDKYILRQHIKHMHVEQQAVDCETCGKTFKNHRNLKIHLTNVCMKPVQLHPCAICGKQFRHKNKLKDHMASCTPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107143;
90% Identity: iTF_00107143; iTF_00101133;
80% Identity: -