Aplu004483.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles plumbeus
Gene Symbol
egg
Assembly
GCA_034621735.1
Location
JAOEFI010000004.1:3062243-3065965[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.8 5.7e+03 -2.9 0.0 14 69 215 268 213 271 0.62
2 2 6.4e-15 2e-11 43.4 0.0 9 71 600 657 594 662 0.92

Sequence Information

Coding Sequence
ATGGACAAAGAATGCCAAAATGAGGAACAAGACGATGATCTAACGGAGAACAATGCTGATGCCAAATGTATTAATCCAGATTGTTGTAAAACCTCGAAGGAATTGTTCCTGGCTCCCTTGTTTACAGTGCATTTCTATGCTAttccaaagaagaaaaatgcgcTATACATCTgccaaaaatgtttccaagCTGCTATTGAACAGTATGAGaaATTGGGAGGTATGTTGGTTAATCATCAGCCATTATACTCAGTCGATGTCCCACGAGTAAGCGAGCTAGTAGAGATTTCAGACAGCAGtgacgaagaagatgaaacatCGATCGAAATTGACgAAACACCGCTACCGCCGGAAATCATTTCTCTGGTTGCAACAGAATTGACGGAGACGTTGGAGATGGCATTTAAAAGATATGATATTGGTGAACAAGTTGCAGGCTCCACCTCGATCATAGAAAAGCAACTTAGTCGTATGGAAGTGGAATGCAACGACGTTAACAAGAAAGTGAAGACACTGCGTACCGACCTCGACGAGATACAATATAACCTGTACGATAGTGTGAAGTATACCGTGAAAGAGCTGGCGCCGGTGATTGTTCCAGACGATGAACCCTTACCACTACCATTCTTCGAACGTGAAAACGGTTTCATTCGAACCTCTGCAATCCGGCAGAGACCACCAGTGCAAGTAAATGAAGTGTACTTCGGCATCAAGGGCCAATCGCTGCTCGGGAGCTGGAACGAATGCAGGGTCATCGAGAAATTCTCACAGATGAAATCGCCATCCATGTACAACGTGCAATTTCTGCAGGGCGATGGTCCCGGTTTACTGCTCCCAGGAAAACGTCTCGCCTATAGCACTCCACCGAACGTCAGATTACTCCAGGGTACCCGGGTCATTGCCAAAATTGAGATCATGGAATCCCCTGTAACCGGAGAACCTCAAACTGGAGATTCCTTTTACGCAGGAATCATTGCGGAACCGCTCATCCCATACAATAACCATCGGTATCTGATTATTTTCGACAATGGATACACACTGTACGCTCAGCCTTGGAACGTCCGGGTTGTTTGCGAGCAATCACTGTTCGTTTGGGAAGATGTAGACACTCACTCGAAAGAGTTCGTATTGGACTACTTGAATAATTACAAAACCGTGCGGCCGATGGTGCAGGTGAAGGAAGGCCAGCGGGTGCTGACGGAAAAGAATGCAAAGTGGTACCACGCTATCGTGATGGGAATCGACAGCAGCTTGATGCTGCTACAATTCCCAGAATTGAAgcaaatggaatggatttttcGCGGTTCAAAGCGACTCGCTCCGCTGTACTACGTCCGGAAGCATAAACGGCAGCAAATTTCCAAGTTTCAAAAACGTAACGTTCCTTCTATTGAGTACATTActatcgacgacgacgacgacgacgaccacgacaaCAATGCCCCTGTTGATCATAAGTCGAGCGATGCACAAGCGGATTCTGCCGCTAATGTAGACTATGAGACGGCATCAACCAGCGGAATTGATACGCCACCAGAAGAAAAGGCTTCCGTGTACCTGCAGTCCCGTTTCACGGCCAAAAAGAGCACCGCCGGGCGAGCAAAGGCTCCTGCCCAGACACGGCAGATAGTCATGAACAATAACATCATCTATTGCGACAACGATCGTCCGCAGGGAGTCACGCACATGTACACGACTAAAAATTTTCGCGGTCCCGCTAAATATACTCCCCATGAATGCAGTCCTAACTGTCTTTTCGACATAACATTCGACTTAAAAACGTACAATCTTCTCGCGAGACCGCTGATCTGCGGCTGGGAGCGGCATATTTGCAAATCGCGTGGCAAAAAAGCCGGTGTGGTCGTGTACCGGGCGCCGTGTGGCCGAAGGTTACGTTTCATGTACGAGCTGCATCGCTACTTACGGATCACAAAGGCCTCGCTaaacgtggaaaactttgactTCGACTACGAAATACGGGCTGTGGCGCAATTTAAGCCCGAGAGTTTGATCTTCGAGACGGCCGACCTTTCTCTTGGGAAAGAGTTGATGGCGGTTTCGTGTGTGAACTACTACGACGACACGCAGCCGCCGCCCTGCGAGTATTCCACCGTGCGCATTCCCACTGAGGGGGTCAACTTGAACTTAGACGACAATTTTCTGTGCGGATGCGATTGCGAGGACGACTGTTTCGACAAGAGCAAGTGCCAGTGTTGGCAGCTTACGATCCAGGGTGCACTGCGCAGTAGGCCGAACACGCCTATCGTCAACATCGGGTATGTGTACAAGCGTCTGGACGAGCTGGTGCTGAGTGGCATCTACGAGTGCAACTCGCGCTGCAAATGCAAGGTCAATGAGTGTCTCAATCGCGTCGTGCAGCACCCGTTGCTGACCAAACTACAAGTGTTCAAAACGAGCAACCGGGGTTGGGGCATTCGCTGCTTGAACGACGTCCCAAAGGGGAGCTTCATTTGCATCTACACGGGCCACTTGCTCACGGAGGAAGCGAGCAACTTGATCTGCGCGCAGAACGAGGACAAGACGGGCGACGAATACTTTGCCGATCTCGACTTCATCGAAACGGCCCAGGACCTCAAGGAAGGATACGAGAGTGACGCGATCGAACCGCCGTGGAACCCGTACGACGAATCAAGCGACGAAGAATCGGACAATGAACAGGGCATCGAGACGCAAAATTGTACGCAAGACTCGGACGACGATTTTACTTCTACAAGCAAGCCTTCTGGAAGTATCGTTAAAACACGGGCACAGCTGAAGCAGAGCAAATCGAAGAGTAAATCGTCGCGGCAGAGCACTAAGTCAGGGGAAGAACGTGAGCGAGTTAATCTGATACCAAACTCTCTAATGGGCAAGGCGGATAAGCCTGGGGCAACTAGAAGGCATCTCTCAGTTCGTGAGCTTTTTGGTGAAAACGAGCAAGCGTACGTGATGGACGCGAAGAAATCGGGAAATCTGGGTCGTTACTTTAACCACTCCTGTGTGCCGAACCTGTTCGTCCAGAACGTATTCGTCGATACGCATGACCTGCGCTTCCCTTGGGTGGCTTTCTTCGCTCAACGCAACATCCGGGCTGGTTCGGAGCTAACGTGGAACTACAACTACGACGTCGGATCCGTGCCAGGAAAGGTTCTTTACTGCAATTGCGGAGAGGCAGAGTGCCGAAAACGGTTGCTCTAA
Protein Sequence
MDKECQNEEQDDDLTENNADAKCINPDCCKTSKELFLAPLFTVHFYAIPKKKNALYICQKCFQAAIEQYEKLGGMLVNHQPLYSVDVPRVSELVEISDSSDEEDETSIEIDETPLPPEIISLVATELTETLEMAFKRYDIGEQVAGSTSIIEKQLSRMEVECNDVNKKVKTLRTDLDEIQYNLYDSVKYTVKELAPVIVPDDEPLPLPFFERENGFIRTSAIRQRPPVQVNEVYFGIKGQSLLGSWNECRVIEKFSQMKSPSMYNVQFLQGDGPGLLLPGKRLAYSTPPNVRLLQGTRVIAKIEIMESPVTGEPQTGDSFYAGIIAEPLIPYNNHRYLIIFDNGYTLYAQPWNVRVVCEQSLFVWEDVDTHSKEFVLDYLNNYKTVRPMVQVKEGQRVLTEKNAKWYHAIVMGIDSSLMLLQFPELKQMEWIFRGSKRLAPLYYVRKHKRQQISKFQKRNVPSIEYITIDDDDDDDHDNNAPVDHKSSDAQADSAANVDYETASTSGIDTPPEEKASVYLQSRFTAKKSTAGRAKAPAQTRQIVMNNNIIYCDNDRPQGVTHMYTTKNFRGPAKYTPHECSPNCLFDITFDLKTYNLLARPLICGWERHICKSRGKKAGVVVYRAPCGRRLRFMYELHRYLRITKASLNVENFDFDYEIRAVAQFKPESLIFETADLSLGKELMAVSCVNYYDDTQPPPCEYSTVRIPTEGVNLNLDDNFLCGCDCEDDCFDKSKCQCWQLTIQGALRSRPNTPIVNIGYVYKRLDELVLSGIYECNSRCKCKVNECLNRVVQHPLLTKLQVFKTSNRGWGIRCLNDVPKGSFICIYTGHLLTEEASNLICAQNEDKTGDEYFADLDFIETAQDLKEGYESDAIEPPWNPYDESSDEESDNEQGIETQNCTQDSDDDFTSTSKPSGSIVKTRAQLKQSKSKSKSSRQSTKSGEERERVNLIPNSLMGKADKPGATRRHLSVRELFGENEQAYVMDAKKSGNLGRYFNHSCVPNLFVQNVFVDTHDLRFPWVAFFAQRNIRAGSELTWNYNYDVGSVPGKVLYCNCGEAECRKRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-