Basic Information

Insect: Anopheles melas
Gene Symbol: ZFY
Assembly: GCA_000473525.2
Location: AXCO02002227.1:12845-15616[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 3.2 1.7e+02 2.7 2.0 1 15 48 62 48 65 0.83

2 13 9.8e-05 0.0053 17.0 1.1 2 23 297 318 296 318 0.97

3 13 1.1e-05 0.0006 19.9 0.6 2 23 325 346 324 346 0.97

4 13 0.095 5.1 7.6 0.7 1 23 356 378 356 378 0.94

5 13 2 1.1e+02 3.4 0.1 3 23 403 430 401 430 0.78

6 13 9.5 5.1e+02 1.3 1.1 2 20 437 455 436 458 0.64

7 13 5.3e-07 2.9e-05 24.1 2.7 1 23 496 519 496 519 0.96

8 13 0.0027 0.14 12.5 1.1 2 23 525 546 524 546 0.95

9 13 2.2e-05 0.0012 19.0 2.2 1 23 551 573 551 573 0.94

10 13 0.0059 0.32 11.4 0.1 2 23 582 604 581 604 0.97

11 13 0.00033 0.018 15.3 0.5 2 20 611 629 610 631 0.93

12 13 4.9e-05 0.0026 17.9 0.4 1 23 642 664 642 664 0.99

13 13 0.00052 0.028 14.7 2.6 1 23 670 693 670 693 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	3.2	1.7e+02	2.7	2.0	1	15	48	62	48	65	0.83
2	13	9.8e-05	0.0053	17.0	1.1	2	23	297	318	296	318	0.97
3	13	1.1e-05	0.0006	19.9	0.6	2	23	325	346	324	346	0.97
4	13	0.095	5.1	7.6	0.7	1	23	356	378	356	378	0.94
5	13	2	1.1e+02	3.4	0.1	3	23	403	430	401	430	0.78
6	13	9.5	5.1e+02	1.3	1.1	2	20	437	455	436	458	0.64
7	13	5.3e-07	2.9e-05	24.1	2.7	1	23	496	519	496	519	0.96
8	13	0.0027	0.14	12.5	1.1	2	23	525	546	524	546	0.95
9	13	2.2e-05	0.0012	19.0	2.2	1	23	551	573	551	573	0.94
10	13	0.0059	0.32	11.4	0.1	2	23	582	604	581	604	0.97
11	13	0.00033	0.018	15.3	0.5	2	20	611	629	610	631	0.93
12	13	4.9e-05	0.0026	17.9	0.4	1	23	642	664	642	664	0.99
13	13	0.00052	0.028	14.7	2.6	1	23	670	693	670	693	0.98

Sequence Information

Coding Sequence: ATGGAACAGTTTGTAAATTGCGTACTGTGCTTGACTACCGAGCCGCAAAGCTTTCTCAAGGTGTACAATGAAGAGAAACAGGATACAGACATCGCGTCCGTAATAACAAAACATCTTTGGGTGAAACCGGCCAAGGATTCGTACGTATGTGATGAGTGCTGGAAATGTTTGAACGATTTCCACGAGTTCTACACCAAGCTCGAGAACATACACTATCCGCCCGATCCGGAGGATGCGTCATGCAATGCCAAAGACATCCGACAGTACCTTTTCGAATTTCATCCCGTGGAAGACGTGAAGATCGAGGAATTGTCTCAGAATGCGGAGGACATGGAAGAAATAGAGTACGAGTATTTGGAAGCATGCAACGAAGAAACCATAGACAATGAGAACGCCGAACGTTCTAGCGGTCGTCCGAAACGGGCCAGTGCCGCACAGGCTAACTATAAAATTGAAGCGGCCGAATCGGATCCCTCGAAGGCAAAGCAAGAGCCGGGCACCAAAAAGGAGCCAGCCAGCGAACCGACGTCACCACCGAAAAGGGGTAGAGGTAGGCCTCCGAAGGCAAAAGCCGAGGTCGAAATCAAACCCGAACCGAAATCCAAGCTGCGCCGTCGGGGTCGTAAAAGAAAGGTTTCGGTTAGCAGCAGCGACTCGGAGCTGGAATCCGACTTTGACGATTTTATTGACGGCGAAGACTGGAAGAAGTATCGCAACACGTCGAAGGATAAGGGGAGAAGATCGCTCGGTTTTCGGCAGCTGCAGGAAAAGATATTTTCGTACGTGGATGAATTTATCTGCTACTACTGTCCGGAAAAAATCGTCTTCGAACGGTTTCACCATGCGAATTTGCATTACAAGAAGGTACACAATGAGCCAGCCTTTCTGCGGTGTCCAAAGTGTGGCAAAAAGTGCTTCACACCGGGCGGATTTGTGAGCCACATGGAAACGCACGAAGATCCGGAGCGGAACAAGTGTAAAATCTGCGGCAAGGTTACGGATCAGGAAATCACGCTCAAGAAGCACATGCGAGCGCACCAGGAGAACCTGGAGAAGGACTTTCCGTACCCGTGCAGCCTGTGCAATCGGCGGTTCGAGGAGGAGGAGAAGCGCGATAAACACGAACGGCTGCACGGACGGAAAGTGATCATCAAGAAGGAGAAGGGTCGCGATCTGGAGCTGCTTGAGTTCTACAAACGCATCTACTGTGAAGTGTGTGAAGAGAAAAAGCCCGAATCAACCTCGTTCGATAACTTCTGGGATCTGAAAGTGCACATGGGTAATGAGCACAACAAAACGCCATTCCTAAAGTGCCCAATCTGCTTCAAGAAGAATGTGTGCCGCCAGCAGCTAATGGTGCACGTGGATGTACATAGTAATCCAGAAAACTATCGCTGTGAGGTGTGTAAGGAAATCCATCAGAATCTTGAAAAGCACATGATAAAAGCACACACCCCGGAAACGTCGTTACCGGACGAGAAAAATTACAGCTGCGAACATTGCGGAAAGATGTTCAAATATCAAACGAATCTTAAAAGTCATATCGATCGTGTGCACGGTGTAAAGGATGTATCCTGTGACATCTGCCACAAATATTTCAATAGCAAAGCATTGAGCGCTCACAAACGTTCAGCCCACACGGACGAGATGTTTATGTGCGAACATTGTCCGAAGATGTTCAAAACGCGCAGCGGTCTCGAATCCCACAAGAGTGACCACGACGAAACGTTGCGCAAATCTGTGCAGTGTCTCATCTGTGGCAAGGAGATGCGCCGCGGTGCCAGCATGGCGAAGCACATGAAAACGATCCACTCGCAGGAGGATCCGGTCAGCTGTGATCTATGCGGCAAGGTGTTCCGCACCACGTTCCATATGATGCGGCACCGCGCCAACACGTGCTCGGCCACGATCGACTCACGGCCGTACAAGTGCGAAGTGTGCGGCAAAGGCTTTGCCATGAAGCTCACGATGACCGAGCATATGACAACGCACACGCGCACCAGCCTGTATCAGTGCGCGTTCTGCTTCAAGACCTTCGGGTACATTTCGAATCTGTACAAACACCGGAAGAAGGCTCATCCGCTCGAATGGCAGGAGGTGCAGGCACGGCCTGAACAGGGAATCGCCACCGTAATCGAAATACGCAATTAA
Protein Sequence: MEQFVNCVLCLTTEPQSFLKVYNEEKQDTDIASVITKHLWVKPAKDSYVCDECWKCLNDFHEFYTKLENIHYPPDPEDASCNAKDIRQYLFEFHPVEDVKIEELSQNAEDMEEIEYEYLEACNEETIDNENAERSSGRPKRASAAQANYKIEAAESDPSKAKQEPGTKKEPASEPTSPPKRGRGRPPKAKAEVEIKPEPKSKLRRRGRKRKVSVSSSDSELESDFDDFIDGEDWKKYRNTSKDKGRRSLGFRQLQEKIFSYVDEFICYYCPEKIVFERFHHANLHYKKVHNEPAFLRCPKCGKKCFTPGGFVSHMETHEDPERNKCKICGKVTDQEITLKKHMRAHQENLEKDFPYPCSLCNRRFEEEEKRDKHERLHGRKVIIKKEKGRDLELLEFYKRIYCEVCEEKKPESTSFDNFWDLKVHMGNEHNKTPFLKCPICFKKNVCRQQLMVHVDVHSNPENYRCEVCKEIHQNLEKHMIKAHTPETSLPDEKNYSCEHCGKMFKYQTNLKSHIDRVHGVKDVSCDICHKYFNSKALSAHKRSAHTDEMFMCEHCPKMFKTRSGLESHKSDHDETLRKSVQCLICGKEMRRGASMAKHMKTIHSQEDPVSCDLCGKVFRTTFHMMRHRANTCSATIDSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQEVQARPEQGIATVIEIRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00093670;
90% Identity: iTF_00093670;
80% Identity: -