Basic Information

Insect: Anopheles melas
Gene Symbol: -
Assembly: GCA_000473525.2
Location: KI919937.1:2208-4416[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.8 2.6e+02 2.2 0.1 2 23 262 284 261 284 0.93

2 13 0.24 13 6.3 1.6 1 23 290 312 290 312 0.97

3 13 0.016 0.89 10.0 0.4 1 19 316 334 316 337 0.93

4 13 0.00045 0.024 14.9 1.6 1 23 341 363 341 363 0.98

5 13 3.1e-06 0.00017 21.7 2.1 2 22 372 392 371 392 0.96

6 13 7.1e-05 0.0038 17.4 0.6 2 23 436 458 435 458 0.93

7 13 0.08 4.3 7.8 2.0 1 23 466 488 466 488 0.91

8 13 0.00021 0.011 15.9 0.8 2 23 506 528 505 528 0.92

9 13 0.00088 0.047 14.0 5.1 1 23 535 558 535 558 0.93

10 13 0.0013 0.071 13.4 3.2 1 23 565 587 565 587 0.97

11 13 2.7e-05 0.0014 18.7 2.5 1 23 593 615 593 615 0.97

12 13 4.2e-05 0.0023 18.1 1.0 1 23 621 643 621 643 0.97

13 13 5.5e-05 0.003 17.8 0.3 1 23 649 672 649 672 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.8	2.6e+02	2.2	0.1	2	23	262	284	261	284	0.93
2	13	0.24	13	6.3	1.6	1	23	290	312	290	312	0.97
3	13	0.016	0.89	10.0	0.4	1	19	316	334	316	337	0.93
4	13	0.00045	0.024	14.9	1.6	1	23	341	363	341	363	0.98
5	13	3.1e-06	0.00017	21.7	2.1	2	22	372	392	371	392	0.96
6	13	7.1e-05	0.0038	17.4	0.6	2	23	436	458	435	458	0.93
7	13	0.08	4.3	7.8	2.0	1	23	466	488	466	488	0.91
8	13	0.00021	0.011	15.9	0.8	2	23	506	528	505	528	0.92
9	13	0.00088	0.047	14.0	5.1	1	23	535	558	535	558	0.93
10	13	0.0013	0.071	13.4	3.2	1	23	565	587	565	587	0.97
11	13	2.7e-05	0.0014	18.7	2.5	1	23	593	615	593	615	0.97
12	13	4.2e-05	0.0023	18.1	1.0	1	23	621	643	621	643	0.97
13	13	5.5e-05	0.003	17.8	0.3	1	23	649	672	649	672	0.97

Sequence Information

Coding Sequence: ATGCCACCGGAAACTGGACCAACGTACGAGCTATCGAACGGCACTTGCCGTTTGTGTTTAGAGCACAAGGAAGAACTGATCCCTCTCGAATGCGCTCTGTCGGAAACGGAGCTTATCAACGTCATCGATTGCTTCCTCAAGATAGACATCACCGACAATTGGCCGTTCCAGAACGTATGTGATGATTGTGTCATGCAGGTTCGGTTGATTGAAAAATTACGCGCCCATTTCGATGAAAGAAACCGTATTTTCGATGTGCTGTGGACGCAATACAAGCGAATACACATGCAAGCCGATGGGGCGGGTGGTAGTAGTAAAAAGAAATTGTCCAAAACAGAGGAGAGCAACGTCAACTCTGGCTACGTCATCGAGGGAATGGTGATAGAGAAAACGGAAGTGGAGATACTGCCACCGGACATGTTGCTGAAGGCAGAGGCTGAAACTGAACAGTGTGGCGCCGTCATCAAACAGGAAGAGAACGAAGAAGAGGACCATCTGGTGGAGGAACTGGTGTACGAGGAGCTAACGCTAGACGAAACGGAACTCGACGAGGGTGAGATCATAGAAGAGGACAAGGATACGCTGGAGGGTGAACATGATGGCGAAATGGTAGAGGAACACATTATGGAACATGAGGAAGACGAGATTGCGGCAATTGACGACGAATCGGACGACCAAATTGAGCACCAGCTGTACGAGATTGAAGACAATGAGGACAGTGGGGAGCAAAAACAGCAGCAGGAGCAGCAGCAGGATGACTGTTATTACGACGAAACGGTCAGCCGATGCTACATCTGCATGGAAACGCTGGAATCGGAGAGCGTGCTGCAAGAGCACCTGGGGACGGTGCATCTTAAATTGCTCCCATTTCACTGCGACAAATGTTTGCAGTACTATCGCACAATCGACGAGGTAAATCAGCACCTGATCTCGCACGAGTATCCGTTCGTTTGCATGTACTGCCCGCGCAAGTACAGCTCCGAGCAGCAGCTGGATAACCACAACAAAGACTGCAACACCTACCGGTGCCTGTACTGCCCGGCGGAGTTCGAAGTTCTCTCCCATCTCACACAACACAAGCGACAACATGCGGCCCAGCTGCGGGGCAAGCTGAAGTGCAAGGCTTGCGGCCGTCAGTTCTCCCAGTCGTCCCATCTGAAGCGCCATCTACGGACGGGGAGCTGTGCCGGCGTCAAGGAACGCGGACCAAAGCGCAAGTACATGCGTAAACAAGGGCAAGAAATTCCGACCTCCCCTAGAGGCGGCGACCAATGCAGCAAGGAGCCGCAGAACAAAAATCTACTCTATTGTCAGGTGTGCGATCGGAAGTTTGTCAGCAACTCCTATCTGGCGCGGCACTTCGAGCGGGACCATTCCGAGCTACGGTTTCCCCTGTTTCCCTGTGATGTCTGTACGAAGAAGTTTACCTCGTTCGAAAAGTCCGTCCTGCACCGACGGTACCACCGCCGGCAGCCAGCCATCAAACCGAAGGAGCTAAAACAACCGAAGGAAACGGTGTGCAAAATCTGCGGCAAAGAGTTCCGCGTCGACCATCAGCTGTTGCGCCATCTGACTGAGGAGCATTCACTCTCGCTCGAGCTGTTCCAGTGCGACCAGTGTCCGCGCAAGTTTTCGACCGAGTTCAAGCTGCGCAAGCACCATTACAACAGCCACCGGGAGAACAAGACCCTGTACGTTTGCTCGCACTGTGGGCAGAAGTTCGAGAAGAAGCTGACGCTGAAGGACCACGAAACGAAGCACCTGGGTATGCCGGCCTATCGGTGCGCGGTGTGCGACAAGACGTTCATTCACAAGCACAGCCTGGACCGGCACGCGCTCGTGCACAGTGACGAGAAGCAGTTCGCGTGCGAGTTTTGCGCGAAAACGTTCAAGCGCAACACCACGCTGGTGATCCACCGGCGGATACACACCGGGGAGAAGCCGTACCAGTGCGAACCGTGCGGTATGCGGTTCATCGATTCCAGCACGCTGATCAAACACCGGCAGCGGGCGCACATGAAAGCGGAGTGCGCGCCGTTGAAACAGGAACAAGGGCAGTAG
Protein Sequence: MPPETGPTYELSNGTCRLCLEHKEELIPLECALSETELINVIDCFLKIDITDNWPFQNVCDDCVMQVRLIEKLRAHFDERNRIFDVLWTQYKRIHMQADGAGGSSKKKLSKTEESNVNSGYVIEGMVIEKTEVEILPPDMLLKAEAETEQCGAVIKQEENEEEDHLVEELVYEELTLDETELDEGEIIEEDKDTLEGEHDGEMVEEHIMEHEEDEIAAIDDESDDQIEHQLYEIEDNEDSGEQKQQQEQQQDDCYYDETVSRCYICMETLESESVLQEHLGTVHLKLLPFHCDKCLQYYRTIDEVNQHLISHEYPFVCMYCPRKYSSEQQLDNHNKDCNTYRCLYCPAEFEVLSHLTQHKRQHAAQLRGKLKCKACGRQFSQSSHLKRHLRTGSCAGVKERGPKRKYMRKQGQEIPTSPRGGDQCSKEPQNKNLLYCQVCDRKFVSNSYLARHFERDHSELRFPLFPCDVCTKKFTSFEKSVLHRRYHRRQPAIKPKELKQPKETVCKICGKEFRVDHQLLRHLTEEHSLSLELFQCDQCPRKFSTEFKLRKHHYNSHRENKTLYVCSHCGQKFEKKLTLKDHETKHLGMPAYRCAVCDKTFIHKHSLDRHALVHSDEKQFACEFCAKTFKRNTTLVIHRRIHTGEKPYQCEPCGMRFIDSSTLIKHRQRAHMKAECAPLKQEQGQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00095800;
90% Identity: iTF_00095800;
80% Identity: -