Amel007373.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles melas
Gene Symbol
-
Assembly
GCA_000473525.2
Location
AXCO02012355.1:1184-9384[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 1.8 94 3.6 7.8 1 23 827 850 827 850 0.96
2 24 0.0024 0.13 12.6 3.8 1 23 856 878 856 878 0.99
3 24 0.079 4.3 7.8 0.2 1 23 927 950 927 950 0.95
4 24 0.00041 0.022 15.0 1.0 2 23 958 979 957 979 0.96
5 24 0.31 16 6.0 0.2 3 23 1016 1037 1014 1037 0.93
6 24 0.19 10 6.7 0.0 1 23 1050 1073 1050 1073 0.95
7 24 0.0006 0.032 14.5 1.6 1 23 1170 1192 1170 1192 0.99
8 24 9.8e-05 0.0053 17.0 1.0 1 23 1288 1310 1288 1310 0.98
9 24 0.00071 0.038 14.3 3.5 1 23 1317 1339 1317 1339 0.98
10 24 5.7e-05 0.0031 17.7 1.3 1 23 1351 1374 1351 1374 0.94
11 24 1.4e-05 0.00076 19.6 0.9 1 23 1400 1422 1400 1422 0.98
12 24 6 3.2e+02 1.9 0.1 1 23 1436 1459 1436 1459 0.87
13 24 0.6 32 5.1 2.1 1 23 1549 1571 1549 1571 0.98
14 24 0.0013 0.069 13.4 1.3 2 23 1600 1621 1599 1621 0.98
15 24 0.0048 0.26 11.7 5.2 2 23 1654 1675 1653 1676 0.94
16 24 7.3e-05 0.0039 17.4 5.3 1 23 1682 1704 1682 1704 0.98
17 24 0.00053 0.029 14.6 0.1 1 23 1799 1821 1799 1821 0.99
18 24 0.2 11 6.6 11.3 2 23 1850 1871 1850 1872 0.95
19 24 0.072 3.9 7.9 7.6 1 23 1878 1900 1878 1901 0.95
20 24 0.00017 0.0092 16.2 0.8 1 23 1971 1993 1971 1993 0.98
21 24 0.0045 0.24 11.8 0.8 2 23 2029 2050 2028 2050 0.96
22 24 0.35 19 5.8 3.2 2 23 2183 2204 2182 2205 0.94
23 24 0.0041 0.22 11.9 5.8 1 23 2211 2234 2211 2234 0.96
24 24 2.3 1.3e+02 3.2 1.3 1 12 2250 2261 2250 2262 0.87

Sequence Information

Coding Sequence
ATGGAATGGGGCGACAGCCTGGCAACGGAACGCGTCATTGCCGGAGGGGGCGGGACCGTCGTCACCACCGTCGGCTCGCCGATGACGCCCGGGCTCGGCGGGCACCATCACCATCAGGGGGCGGCGGACGTCGGCGTCACGTTCGTCACGCACGGCGGGTATGGCAATGAGGCGGGCCAGCGGCGCATGATAGCGACGGCCGGCGTGGCACAGTATGCGGCCGGCCGGGTGGTGGACGGGACGGCGGGCGGCTCCGGCGCCGGGTACTTCCACGATCAGCTGGCCGCCCACGGCCAGTCCGTGGTGGGCACCGCGATGGGCCACTTTGTCGCGGTGGAAGCGACGGGCGGGGGCGCTTACACAACGGGCGGCATCGGGGGCGGCGGCGGTCGGACGGTCGGCCCGATGGTGGCCAGCCCGAACGCGGCCTCCCCCCCGGGTGTACCCGGCATGGGCGGGGGCAATGCGTACGGCCATGCGGCCGGCACACCGACCCACGTGGCGTCCTATCTGCAGCAGCAGGGATCGCCGTTCTCGGCGGCCGTCTCGCTACCGTCGTCCAGCCCGTGCCTGGTCGATGCGACCGCCGTCGGTGGACAGATAGTGGCCTCCTGCTCGAAGGCCTCCGAGATGGTGCTGAACAATGAGGCGCTCAAGGTGGCCAACCAGATGCCGGTCATTACCCAGCAGCAGCAGCAGCCGAGGGCAACGCAGATGTACGGCCTGCAAGGGTCGGGACCGATGGAGGTGTCGCTCGAGTCGGAGTTTAGCTTCCCGGGTGTCGACCAAAGCGACAATGTCCAGCAGCAACAGCAGCAGCAACAACAGCAACAACAATCTCTCTCCCTTACCCTCAGCGGCAACGGTGGCCAAGCGCCCGTCGCCCGACCGGAACCGCCAAACGAACGCATCACACGCTCGTCCACCGCGAACAATCGGGCCGCGGCCCGGCTAACCGCCAACGAAGCTTCCGGCGACGGGGAAGCCGCCCTCGAGGAGGGCCTTCCGTCCGATTCGCTCACCAGCAACGACCTGCACTCGGTGCTGGACGGGAAGCTGCTCGCGGACACGAAGCCAAACATCAACAACATGCTGTCCCAGGGTGGCGATGGCCAGCAGCAGCAGTTGACCCCGGCGATGGTGCTGCCCCAGTCCGACCAGCCCCGCAAGCGCTCCGTCAAGCACGTGCGCTTTGTCGAGCCGAACGAGGAGAACTCGTACGACGGGATGCGGCAGACGCGCGGCAACGTCGTGTCGCCCCATCCGCTCGGGCTGGGCCAGCGCTCCGACGACAACGAGCAGGACGAGGAAGAGGACGACGAGGAGGAAGACGAGGAGGAGGACGAGGAGGGCGGGGAGGAAGAGGAGGAGGAGGAGGACGATATGGATGGGCTGTCGCTGATGCAGAACCTGCCGCCGGTGGAGAGTTTGCTGGTCGAGATGGACGAACCGCTCGAGGAGGAGAACGACGACGAGGAGGTGGAGATGGAGGACGACGACGACAACGGGAGCCGGCGCCGCCTGTCTGGAAGGCGGGGGCGGCGCGGTGGCCACCACCTGTCCGGGCTGCACCGTCCGGGCCGGCCGCCCAAGCACAGCGAGTCGATCGAGCTCGAGCTGGAACCGCTGCTGCCGGAAATCGAGATGAGCGAGGGTGTGGGCGGTGGCCCGGGCGGGGCCAGCGGTGCGGGCGACGAGAAGGGCGACGAGCAGCAGCGGATCCCGCCGGTGGCGCACGTGTGCCGCGTCTGCCTGTGCGACGAGAAGCCGGCCGGCGAGGACGGCGAGGTGCGCCCGATGGAGTCGCTCTACTGCACGGTCGTGCCGGAGTACCAGTCCCGCAGCCTGTACTCGATCCTGGTCGCCGTCTGCCACCCGCTACATCTCGGCAGCAACGCCGGCATGCCGGACCGGATATGCGCCCCGTGCAAGACGAAGCTGCTGGCCGCGTACGAGCTGTACGACATGTGCCTGCGCAACGACGAGATGCTGCGCCGCAAGTACCAGGAGAAGCTGCTGCTCGCGTCCAGTGCGGCCGGCGGCGGGGGCGAGATGCGCCGCATCAAGAAGGAAAAGCTGGACAACAACGGTGTCGATGCGCTCGGGGGGGACGACGACGAGGACGACTACTACCGTGGCGGCATGCCGAAGCGTGGCTCGATGCGCGTGAACGATCACGACGACACATATCTGTACGATCGGCAGTACCCGCTGCATTCGGCCAGCGCCGTCGCGGGCAGAAACTCCACCATCGCGGCCTTGCAGTCCCGCTTCCAGCACCAGCAGCAGCCATCGCACGGAAGATGGGGTAAATATCAGCGCCACCAGTCGCAGCTGCACCAGGTGGCGAACGGGCCGGAAGCGCTGCGCCAGCTGCACGACGGCCGGATGAAGCAGGCGGGCGCAGGCGGCGGCGCCGCCCGTTCGGCCGCCAACTACGACTACAACGCATTCCACCGCGTGCTGCCGAACGGTAGCCACCAGTGCACCAAGTGTATGCGCGAGTTCAAGTACCACAGCTACTACAAGAACCACTACATCAGCCAGCACGATCCGAGCAAGCCGTTCAAGTGCCGCAAGTGCCACTACACCTTCCTGACCGAGCGGTGGCTGATCGTGCACATGCGCACGCACATTGCGGCGGGCGATCTGATGCCGCTGGCCGGTGGGCCGGCGGCGGCGGCGGCGGCGACCCAGGGCGCGTCCGATGCCGGTGCGGTCGATTCGTTCGACTCGTCGCTGGACGGCAGCGTGGAGCGGAGGAAGGGGGCGCGCGGCTTCGATTGCTACTACTGCGACATGACGTTCCCGGCGATCGCGCTGCAGAAGCGCCACATGCTGTCGGTTCACGCGGACAAGCATCGCGGGCTGGAGTGCCCGATCTGTCAGTGCCGGTTCGCGAACCAGTCCAGCTTCCTGATCCACCTGAAGGAGCACAAGGAGCAGAAGCGATTGCGCAACAGCAGCGGCGGCAAGCAGGAGGAGACCGGCGGCAAGGGAGAGGACGCTGCGGCCAGCAGTGCGGCGGTGAAGCGCGAGTACGGCTGCACCGTCTGTGCGGTGACGTTTGCGCGCGAGGTGCTGCTGAACGAGCACCTGCACGAGCAGCATCCGGACGCGTTTTTGGCGCAAAACAGCGACCTGGCGTACATGTGTGGCGTTTGTTTGGCCGAGTTTAGCGACCGGGCCGCCCTGGAGGGTCACACGAGCAGCACGCACACGGAGGCGGAGCTGGCGGAGGCGGCGGCAGCAGCAGCAAAGGAAAAGGTGCAGCCACCGGCGGACGAAAGCGAGAGCACCGGCACGCAGCAGGACAATGTTAAGAAGGAGGAAGTGCAGGAAGGGGAGGAAGAGGAGGAGGACGAGGAGGAAGCGGACGATGAGCAAAACGAGCAAAATAATGCCGACGATGGTGTGAAACAACAGCAGCAGCAGCAGCAGGAGGAAGTGGCAGGCGAGGAGGAAACCAAAGGAGCGGAAAAGCCACCGGAGGGCTGCTCGCTGGTGTACAAGTGCAAGCTGTGCCAGTCGCGCTTCGTGACGAAACAGTCGCTGGCCACGCATCTGGAGACGCACGTGGCGGCGATGAAGCGAGCCGCCGGCAAGCGGCCGTACAGTGAAACGGGCGACGGCGAGGGCGGTGACGGTGCAGACGGTGGTGGTGGTGCCGACGAGGACGACTACAGTGGCGAGGACGACGACGAGGAGGAGGAGTACGGTGGGGCGCAGAACGCGGGTGGGGAGAAGCGCCCCAAACGCGCCAAGCCGCAGGCGGCCGAGGAGGACGACGACACGACGACGGAGGAGATGCCGATCGATCCGGACGAGATCTCGTTCAACCCGGACACGGGCGAGCAGATGTTCACGTGCCAGGTGTGCGGCAAGGTGATCAACACGGTGTCGCAGTTCCGCCGGCACAAGCGCGTCCACTCGCCCAAGGGCCGGCCGTTCGAGTGCCACATCTGCTTCTACCGGTTTGCGATGAAGTACAGCTACACGGCGCACATGCTGCGGCACGAGCTGGGCTGCAATCCGACCCAGCCGACCACGTACCGTTGCACCAAGTGCTCGGAAACGTTCACGCGCCGCAAGCTGCTCAGCCAGCACATGGCGGCCATGCACGGGCGCTGGTCGGACGGGGGCAGCCCGATGTACGGGTCGCCGGGCCAGCCCGGGTCGACCAGCGGCCGCGGCACGCACACCTGCCCGATCTGCTCGGAGTCGTTCACGCGCGAGAGCGTGCTGAACGGGCACATGAAGACGCACAACCTGGAGGCGGCGCAGCTACAACACTCCGAGGTGTGCTACCTGTGCCGCGTCTGCAGCAACGAGTACGAGTCGCGCGAGCAGTACGAGGCGCACGCGGCCGAAGCCCACCCGGGCATGAAGATGGAGATGGTGGAGGCGGGCGTGTCGGCGGACGTGCTGCAGAAGCTGGGCAATGTGCTGGATGCGGCTGCGGCTGCAGCCACTGCGTCACAGGACGGCGACGGGAACGCTGCGATCAAGACCGAGGAGAAGCGTGACAATGGCGCCGAGGGCGAGGAGGAGGAGCGTGCCGGGGCTGGCGGGGACGGCGGGGAGGAGGAGAACGGGGAGCAGAAGAGTGCGACCAGTGCCGCCGGCGGGGGTTTTACGCTCATCTTCAAGTGCAAGCTGTGCTCGGGCCGCTTCCTCAAGAAGAAAACGCTCGACTGGCATCTGCAGACGCACCGGTCGATCGCGAAACAGGGCGACGGTGTGGCGATACTGCCCGATCTGGGACCGGACGCGATCGGTGACCAGCCCAAGATGAGCAAGTGTACGGTGTGCGGACAGATCTTCGACAATGAGCTGCTCTTCCACGAGCATATGCGCACCCATCAGCGCGGTCCGCGGCCGGGTATCCACCTGGGGTACGGAGGGATGGCGCAGCAGCCGCCAACGAGGCGCCGGCGAACCGGTGGCCGCAGCCTGATCCAGTGCGATCTGTGCAAAAAGACGTTCATGTACCGCAGCCAGCTGCACCAGCACACGATGCTGCACCATCAGCCGGGCAAGCCGTACGAGTGCAAGATCTGCCACTACAGCTTCGTGCACAAGCTGAACCTGAAGCGCCACGAGCTGACGCATCTGCGCGAACCGCCCCGCCAGCTGCTCGACCAGCAGCAGCAGCAGCGGGACGCGGATCAGGACGATCAGCTGGACAACTCGCACCTGCTGCAGCCGCTTGTGCTGATGGCCGGCGGCACGGAAGAGGAAGCGACGAACGGTCGGGGACGTGGTGGTGGTGCGGCCGGAACCGCCCAAGACGATGGTGGCGACGGCGATCAGTCCGGCTCGGCAATGGATGGCTCGAGCGCGGCCGACGACGGTACGACGGGCGGCAGCGGGCGGTCCTGGACGGCGAAGAAGTTCAAGTGCGTCGTGTGCGCGCTGGTGTTTAACCGGCAGAACGAGCTGGTGGTGCACCTGCAGACCCACATCGAGCGCATCAACGAGGTGAAGAACCGTACGGCAGCGGCGGTCGCTTCGGCGGCAGACGCCGGCATCGCGCCGACCGATCGGCAGTGCAAGCTGTGCCACAAGGTGTTCAAGTTCAGCTGCCAGCTGAAGCAGCACCATCTGCTGCACCACGCGCGGGAGAAACCGTTCGAGTGCCGCACCTGCCACTATCGGTTCGAGTTCAAGGGCCACCTGGTGCGGCACCGGGCCAACCACCATCCGAACGAGGCGAAGGAGGACCAGGACTTCCCGAGCCCGTACCTTACGTCCACCCCGCTGCGGGGTGCGCGCGGCGGCGGCTATGGGGGGGAGGCCAGCAGCAGCAGCCAGGGCAGCGGCAGCGTGCCAAAGTACGGCGGCATGGTGACGGACGACGTGATTATCGCGCCGACCACGTCCTCGCCCCGGTCGGAGAGTGGGTCGGCCCACCAGTGCCCGATGTGCTCGCTCAAGTTCATCAAGGCGCGCTCGCTGGCCATGCACATGCGGATACATCTCGGCGGGCGGAAGCTGCGCCGCGTCATACCGGCCTCGACGGCGGCTCCGTCGCCGCCGGGTGAGGCGCAGCCCGGTACGCCGACGACGGGGGCGGACAAGCTGGTGTGTCGGTTCTGCGCCGGCACGTTCCCGACGGCACACGAGCTGAAGACGCACATGATGACGCACATCGGCAGCGAGGCGATGGATCTGGAGGTGCCGTTCGGTATCAGCGCGTTCAATCTGCTGCACGAGAACATGTTTAACGATTCGATGGGCGGCGAGGGTGGCTCGTCGGCCGGGGCGCTCGGCGGCGAAGATCACAGCAGTATGGGCGGCGAGGGTGGCAGCAACAGCCGAGCGGAGGGTGGCAGCACGGACGGCGACTATCAGCAGGACGATGGCGAGGACGGTAGCGGCGGTGATCCACTGTTCGACGGCTCCAATCTGGAGCTCCGGCACATGAACCTGATGGCGACGCACCGGTCGCGGCTCGCGGCCACGGCCGCCCTGTCCGCCCGGCTGCAGGCAACCCCCTCCGCCTCCTCCTCGTCGCAGTCGTCCTCGTCGGCGAAGGGCAAGATTGTGTGCGAGCTGTGCAAGAAGGAGTTCCTCTACCCGTGCAACCTCAACCAGCACAAGCAGCTGCACCATTCAAAGGAGAAGCCGCACGAGTGCCGCATCTGCCACTATCGCTTCGAGTACGTCGGCCACCTGCAGCGGCACATCCGGCAGCAGCACGAAAAGATGGCGGAGGAGCTGCTGGCGCCGGCGGAACCTCAAACGTTCGATTGCAACTTTTGCGGCGAATCGTTCGACTCGAAGC
Protein Sequence
MEWGDSLATERVIAGGGGTVVTTVGSPMTPGLGGHHHHQGAADVGVTFVTHGGYGNEAGQRRMIATAGVAQYAAGRVVDGTAGGSGAGYFHDQLAAHGQSVVGTAMGHFVAVEATGGGAYTTGGIGGGGGRTVGPMVASPNAASPPGVPGMGGGNAYGHAAGTPTHVASYLQQQGSPFSAAVSLPSSSPCLVDATAVGGQIVASCSKASEMVLNNEALKVANQMPVITQQQQQPRATQMYGLQGSGPMEVSLESEFSFPGVDQSDNVQQQQQQQQQQQQSLSLTLSGNGGQAPVARPEPPNERITRSSTANNRAAARLTANEASGDGEAALEEGLPSDSLTSNDLHSVLDGKLLADTKPNINNMLSQGGDGQQQQLTPAMVLPQSDQPRKRSVKHVRFVEPNEENSYDGMRQTRGNVVSPHPLGLGQRSDDNEQDEEEDDEEEDEEEDEEGGEEEEEEEDDMDGLSLMQNLPPVESLLVEMDEPLEEENDDEEVEMEDDDDNGSRRRLSGRRGRRGGHHLSGLHRPGRPPKHSESIELELEPLLPEIEMSEGVGGGPGGASGAGDEKGDEQQRIPPVAHVCRVCLCDEKPAGEDGEVRPMESLYCTVVPEYQSRSLYSILVAVCHPLHLGSNAGMPDRICAPCKTKLLAAYELYDMCLRNDEMLRRKYQEKLLLASSAAGGGGEMRRIKKEKLDNNGVDALGGDDDEDDYYRGGMPKRGSMRVNDHDDTYLYDRQYPLHSASAVAGRNSTIAALQSRFQHQQQPSHGRWGKYQRHQSQLHQVANGPEALRQLHDGRMKQAGAGGGAARSAANYDYNAFHRVLPNGSHQCTKCMREFKYHSYYKNHYISQHDPSKPFKCRKCHYTFLTERWLIVHMRTHIAAGDLMPLAGGPAAAAAATQGASDAGAVDSFDSSLDGSVERRKGARGFDCYYCDMTFPAIALQKRHMLSVHADKHRGLECPICQCRFANQSSFLIHLKEHKEQKRLRNSSGGKQEETGGKGEDAAASSAAVKREYGCTVCAVTFAREVLLNEHLHEQHPDAFLAQNSDLAYMCGVCLAEFSDRAALEGHTSSTHTEAELAEAAAAAAKEKVQPPADESESTGTQQDNVKKEEVQEGEEEEEDEEEADDEQNEQNNADDGVKQQQQQQQEEVAGEEETKGAEKPPEGCSLVYKCKLCQSRFVTKQSLATHLETHVAAMKRAAGKRPYSETGDGEGGDGADGGGGADEDDYSGEDDDEEEEYGGAQNAGGEKRPKRAKPQAAEEDDDTTTEEMPIDPDEISFNPDTGEQMFTCQVCGKVINTVSQFRRHKRVHSPKGRPFECHICFYRFAMKYSYTAHMLRHELGCNPTQPTTYRCTKCSETFTRRKLLSQHMAAMHGRWSDGGSPMYGSPGQPGSTSGRGTHTCPICSESFTRESVLNGHMKTHNLEAAQLQHSEVCYLCRVCSNEYESREQYEAHAAEAHPGMKMEMVEAGVSADVLQKLGNVLDAAAAAATASQDGDGNAAIKTEEKRDNGAEGEEEERAGAGGDGGEEENGEQKSATSAAGGGFTLIFKCKLCSGRFLKKKTLDWHLQTHRSIAKQGDGVAILPDLGPDAIGDQPKMSKCTVCGQIFDNELLFHEHMRTHQRGPRPGIHLGYGGMAQQPPTRRRRTGGRSLIQCDLCKKTFMYRSQLHQHTMLHHQPGKPYECKICHYSFVHKLNLKRHELTHLREPPRQLLDQQQQQRDADQDDQLDNSHLLQPLVLMAGGTEEEATNGRGRGGGAAGTAQDDGGDGDQSGSAMDGSSAADDGTTGGSGRSWTAKKFKCVVCALVFNRQNELVVHLQTHIERINEVKNRTAAAVASAADAGIAPTDRQCKLCHKVFKFSCQLKQHHLLHHAREKPFECRTCHYRFEFKGHLVRHRANHHPNEAKEDQDFPSPYLTSTPLRGARGGGYGGEASSSSQGSGSVPKYGGMVTDDVIIAPTTSSPRSESGSAHQCPMCSLKFIKARSLAMHMRIHLGGRKLRRVIPASTAAPSPPGEAQPGTPTTGADKLVCRFCAGTFPTAHELKTHMMTHIGSEAMDLEVPFGISAFNLLHENMFNDSMGGEGGSSAGALGGEDHSSMGGEGGSNSRAEGGSTDGDYQQDDGEDGSGGDPLFDGSNLELRHMNLMATHRSRLAATAALSARLQATPSASSSSQSSSSAKGKIVCELCKKEFLYPCNLNQHKQLHHSKEKPHECRICHYRFEYVGHLQRHIRQQHEKMAEELLAPAEPQTFDCNFCGESFDSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00093607;
90% Identity
iTF_00102511;
80% Identity
-