Agam010882.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles gambiae
Gene Symbol
-
Assembly
GCF_000005575.2
Location
NT:14443386-14464048[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 1.3 67 3.7 7.8 1 23 449 472 449 472 0.96
2 25 0.0018 0.092 12.8 3.8 1 23 478 500 478 500 0.99
3 25 0.06 3 8.0 0.2 1 23 548 571 548 571 0.95
4 25 0.00031 0.016 15.2 1.0 2 23 579 600 578 600 0.96
5 25 0.27 14 5.9 0.2 3 23 637 658 635 658 0.93
6 25 0.14 7.1 6.8 0.0 1 23 671 694 671 694 0.95
7 25 0.00045 0.023 14.7 1.6 1 23 791 813 791 813 0.99
8 25 7.4e-05 0.0038 17.1 1.0 1 23 909 931 909 931 0.98
9 25 0.00053 0.027 14.4 3.5 1 23 938 960 938 960 0.98
10 25 4.3e-05 0.0022 17.9 1.3 1 23 972 995 972 995 0.94
11 25 1.1e-05 0.00054 19.8 0.9 1 23 1021 1043 1021 1043 0.98
12 25 4.5 2.3e+02 2.1 0.1 1 23 1057 1080 1057 1080 0.87
13 25 0.45 23 5.2 2.1 1 23 1170 1192 1170 1192 0.98
14 25 0.00097 0.049 13.6 1.3 2 23 1221 1242 1220 1242 0.98
15 25 0.0036 0.18 11.8 5.2 2 23 1275 1296 1274 1297 0.94
16 25 5.5e-05 0.0028 17.5 5.3 1 23 1303 1325 1303 1325 0.98
17 25 0.0004 0.02 14.8 0.1 1 23 1422 1444 1422 1444 0.99
18 25 0.15 7.5 6.7 11.3 2 23 1473 1494 1473 1495 0.95
19 25 0.054 2.8 8.1 7.6 1 23 1501 1523 1501 1524 0.95
20 25 0.00013 0.0065 16.4 0.8 1 23 1594 1616 1594 1616 0.98
21 25 0.0034 0.17 11.9 0.8 2 23 1652 1673 1651 1673 0.96
22 25 0.26 13 6.0 3.2 2 23 1898 1919 1897 1920 0.94
23 25 0.0031 0.16 12.0 5.8 1 23 1926 1949 1926 1949 0.96
24 25 0.00016 0.008 16.1 0.6 1 23 1965 1988 1965 1988 0.96
25 25 0.00074 0.038 14.0 1.5 1 23 1994 2016 1994 2016 0.96

Sequence Information

Coding Sequence
ATGGTGCTGCCCCAGTCCGACCAGCCCCGCAAGCGCTCCGTCAAGCACGTGCGCTTTGTCGAGCCGAACGAGGAGAACTCGTACGACGGGATGCGGCAGACGCGCGGCAACGTCGTGTCGCCCCATCCGCTCGGGCTGGGCCAGCGCACCGACGACAACGAGCAGGACGAGGaagaggacgacgaggaggaggacgaggaggaggacgaggagggcggggaggaagaggaggaggaggaggacgataTGGATGGGCTGTCGCTGATGCAGAACCTGCCGCCGGTGGAGAGTTTGCTGGTCGAGATGGACGAACCGCTCGAGGAGGAgaacgacgacgaggaggtgGAGAtggaggacgacgacgacaatgGGAGCCGGCGCCGCCTGTCCGGAAGGCGGGGGCGACGCGGTGGCCACCACCTGTCCGGGCTGCATCGCCCGGGCCGGCCGCCCAAGCACAGCGAGTCGATCGAGCTCGAGCTGGAACCGCTGCTGCCGGAAATCGAGATGAGCGagggtggcggcggcggcctgGGCGGGGCCAGTGGTACGGGCGACGAGAAGGGCGACGAGCAGCAGCGGATCCCGCCGGTGGCGCACGTGTGCCGCGTCTGCCTGTGCGACGAGAAGCCGGCCGGCGAGGACGGCGAGGTGCGCCCGATGGAGTCGCTCTACTGCACGGTCGTGCCGGAGTACCAGTCCCGCAGCCTGTACTCGATCCTGGTCGCCGTCTGCCACCCGCTACATCTCGGCAGCAACGCCGGCATGCCGGACCGGATATGCGCCCCGTGCAAGACGAAGCTGCTGGCCGCGTACGAGCTGTACGACATGTGCCTGCGCAACGACGAGATGCTGCGCCGCAAGTACCAGGAGAAGCTGCTGCTCGCGTCCAGTGCGGCCGGCGGCGGGGGCGAGATGCGCCGCATCAAGAAGGAAAAGCTGGACAACAACGGTGTCGATGCGCTCGGGGGGgaccacgacgacgaggaTGACTACTACCGTGGCGGCATGCCGAAGCGTGGCTCGATGCGCGTGAACGATCACGACGACACATATCTGTACGATCGGCAGTACCCGCTGCATTCGGCCAGCGCCGTCGCGGGCAGAAACTCCACCATCGCGGCCTTGCAGTCCCGcttccagcaccagcagcagccatcgcACGGAAGATGGGGCAAATATCAGCGCCACCAGTCGCAGCTGCACCAGGTGGCGAACGGGCCGGAAGCGCTGCGCCAGCTGCACGACGGCCGGATGAAGCAGGCGGGCGCAGGCGGCGGCGCCGCCCGTTCGGCCGCCAACTACGACTACAACGCATTCCACCGCGTGCTGCCGAACGGTAGCCACCAGTGCACCAAGTGTATGCGCGAGTTCAAGTACCACAGCTACTACAAGAACCACTACATCAGCCAGCACGATCCGAGCAAGCCGTTCAAGTGCCGCAAGTGCCACTACACCTTCCTGACCGAGCGGTGGCTGATCGTGCACATGCGCACGCACATTGCGGCGGGCGATCTGATGCCGCTGGCTGGTGgcccggcggcggcggcggcgacccAGGGCGCGGCCGATGCCGGTGCGGTCGATTCGTTCGACTCGTCGCTGGACGGCAGCGTGGAGCGGAGGAAGGGAGCGCGCGGCTTCGACTGCTACTACTGCGACATGACGTTCCCGGCGATCGCGCTGCAGAAGCGCCACATGCTGTCGGTTCACGCGGACAAGCATCGCGGGCTGGAGTGCCCGATCTGTCAGTGCCGGTTCGCGAACCAGTCCAGCTTCCTGATCCACCTGAAGGAGCACAAGGAGCAGAAGCGATTGCgcaacagcagcggcggcaAGCAGGAGGAGGCAGGCGGCAAGGGAGAGGACGCTGCGGCCGGCAGTGCGGCGGTGAAGCGCGAGTACGGCTGCTCCGTCTGTGCGGTGACGTTTGCGCGCGAGGTGCTGCTGAATGAGCACCTGCACGAGCAGCATCCGGACGCGTTTTTGGCGCAAAACAGCGACCTGGCGTACATGTGTGGCGTCTGTTTGGCCGAGTTTAGCGACCGGGCCGCCCTGGAGGGTCACACGAGCAGCACGCACACGGAGGCGGAGCTGGCGgaggcggcggcagcagcggcaaagGAAAAGGTGCAGCCGCCGGCGGCCGAAAGCGAGAGCACCGGCTCGCAGCAGGGCGATGTTAAGAAGGAAGGAGAGCAGGAaggggaggaagaggaggaggaggaggaagcggaCGATGAGcaaaacgagcaaaacaaTGCCGATGATGGTgtgaagcaacaacagcagcagcagcagcaggaggaagCGGCGGGCGAGGAGGAAACCAAAGGAGCGGAAAAGCCACCGGAGGGCTGCTCGCTGGTGTACAAGTGCAAGCTGTGCCAGTCGCGCTTCGTGACGAAACAGTCGCTGGCCACGCATCTGGAGACGCACGTGGCGGCGATGAAGCGCGCCGCCGGCAAGCGGCCGTACAGTGAAACGGGCGACGGCGAGGGCGGCGACGGTGCGGAgggtgctggtggtgccgaCGAGGACGACTACAGTggcgaggacgacgacgaggaggaggagtacgGTGGGTCGCAGAACGCGGGCGGAGAGAAGCGCCCCAAACGCGCCAAGCCGCAGGCGGCCGAGGAGGATGACGACACGACGACGGAGGAGATGCCGATCGATCCGGACGAGATCTCGTTCAACCCGGACACGGGCGAGCAGATGTTCACGTGCCAGGTGTGCGGCAAGGTGATCAACACGGTGTCGCAGTTCCGCCGGCACAAGCGCGTCCATTCGCCCAAGGGCCGGCCGTTTGAGTGCCACATCTGCTTCTACCGGTTCGCGATGAAGTACAGCTACACGGCGCACATGCTGCGGCACGAGCTGGGCTGCAATCCGACCCAGCCGACCACGTACCGCTGCACCAAGTGCTCGGAAACGTTCACGCGCCGCAAGCTGCTCAGCCAGCACATGGCGGCCATGCACGGGCGCTGGTCGGACGGGGGCAGCCCGATGTACGGGTCGCCGGGCCAGCCCGGGTCGACCAGTGGCCGCGGCACGCACACCTGCCCGATCTGCTCGGAGTCGTTCACGCGCGAGAGCGTGCTGAACGGGCACATGAAGACGCACAACCTGGAGGCGGCGCAGCTGCAACACTCCGAGGTGTGCTACCTGTGCCGCGTCTGCAGCAACGAGTACGAGTCGCGCGAGCAGTACGAGGCGCACGCGGCCGAAGCCCACCCGGGCATGAAGATGGAGATGGTGGAGGCGGGCGTGTCGGCGGACGTGCTGCAGAAGCTGGGCAATGTGCTGGATGCGGCTGCGGCTGCAGCTACTGCGTCACAGGACGGCGACGGCAACGCTGCGGTCAAGACCGAAGAGAAGCGTGACAATGGCGCCGagggcgaggaggaggagcgtgTCGGGGCTGGCGGGGACGGCGGGGAGGAGGAGAACGGGGAGCAGAAGAGTGCGGCCAGCGCGGCCGGCGGGGGCTTTACGCTCATCTTCAAGTGCAAGCTGTGCTCGGGCCGCTTCCTAAAGAAGAAAACGCTCGACTGGCATCTGCAGACGCACCGGTCGATCGCGAAACAGGGCGACGGTGTGGCGATACTGCCCGATCTGGGACCGGACGCGATCGGCGACCAGCCCAAGATGAGCAAGTGTACGGTGTGTGGACAGATCTTCGACAATGAGCTGCTCTTCCACGAGCATATGCGCACCCATCAGCGCGGTCCGCGCCCGGGTGTCCACCTGGGATACGGAGGGATGGCGCAGCAGCCGCCAACGAGGCGCCGGCGAACCGGCGGCCGCAGCCTGATCCAGTGCGATCTGTGCAAAAAGACGTTCATGTACCGCAGCCAGCTGCACCAGCACACGATGCTGCACCATCAGCCGGGCAAGCCGTACGAGTGCAAGATCTGCCACTACAGCTTCGTGCACAAGCTGAACCTGAAGCGCCACGAGCTGACGCATCTGCGCGAACCGCCCCGCCAGCTgctcgaccagcagcagcagcagcagcagcaggacgcGGATCAGGACGATCAGCTGGACAACTCGCACCTGCTGCAGCCGCTCGTGCTGATGGCCGGCGGTACGGAAGAGGAAGCGACGAACGGTCGGggacgtggtggtggtgcggccGGAACCGCCCAAGACGATGGTGGCGACGGCGATCAGTCCGGCTCGGCAATGGATGGCTCGAGCGCGGCCGACGACGGTACGACGGGCGGCAGCGGGCGGTCCTGGACGGCGAAGAAGTTCAAGTGCGTCGTGTGCGCGCTGGTGTTTAACCGGCAGAACGAGCTGGTGGTGCATCTGCAGACCCACATCGAGCGCATCAACGAGGTGAAAAACCGtacggcggcggcggtcgCTTCGGCGGCGGACGCCGGCATCGCGCCGACCGATCGGCAGTGCAAGCTGTGCCACAAGGTGTTCAAGTTCAGCTGCCAGCTGAAGCAGCACCATCTGCTGCACCACGCGCGGGAGAAACCGTTCGAGTGCCGCACCTGCCACTATCGGTTCGAGTTCAAGGGCCACCTGGTGCGGCACCGGGCCAACCACCATCCGAACGAGGCGAAGGAAGACCAGGACTTCCCGAGCCCGTACCTTACGTCCACCCCGCTGCGGGGTGCGCGCGGCAGCGGCTATGGAGGGgaggccagcagcagcagccagggCAGCGGCAGCGTGCCAAAGTACGGCGGCATGGTGACGGACGACGTGATTATCGCGCCGACCACGTCCTCGCCCCGGTCGGAGAGTGGGTCGGCCCACCAGTGCCCGATGTGCTCGCTCAAGTTCATCAAGGCGCGCTCGCTGGCCATGCACATGCGGATACATCTCGGCGGGCGGAAGCTGCGCCGCGTCATACCGGCCTCGACGGCGGCCCCGTCGCCGCCGGGTGAGGCCCAGCCCGGCACACCGACGACGGGGGCGGACAAGCTGGTGTGTCGGTTCTGCGCCGGCACGTTCCCGACGGCGCACGAGCTGAAGACGCACATGATGACGCACATCGGCAGCGAGGCGATGGATCTGGAGGTGCCGTTCGGTATCAGCGCGTTCAATCTGCTGCACGAGAACATGTTCAACGATTCGATGGGCGGCGAGGGTGGCTCGTCGGCCGGGGCGCTCGGCGGCGAAGATCACAGCAGTATGGGCGGCGAGGGTGGCAGCAACAGCCGGGCGGAGGGTGGCAGCACGGACGGCGACTATCAGCAGGACGATGGCGAGGACGGTAGCGGCGGTGATCCACTGTTCGACGGCTCCAATCTGGAGCTCGTCCTGGAGGATAACATTCTCGATAAAGATTTTGGCATGCGatatcagcagcaacaacagcagcagcagcagcaacagcaaaagcgCCGCTCTGGCAAGTCGGGCCAGAATAATGGTGACGGTGGCGATGATGCCggcgaagaggaggaagacgaTGACGAGGAAAACGAGGACGACGTGACGGACACGAACGATGGGGACGGTGGCGCCggcgaggacgacgaggaggaggacgaggggGAACAGTCGTCCGCGTCGACGATGGCCAGCTTCCAGCGGCACATGAACCTGATGGCGACCCACCGGTCGCGGCTCGCGGCCACGGCCGCCCTATCCGCCCGGCTGCAGGCGACACCCTCCGCTTCCTCTTCGTCGCAGTCGTCCTCGTCGGCGAAGGGCAAGATTGTGTGCGAGCTGTGCAAGAAGGAGTTCCTCTACCCGTGCAATCTCAACCAGCACAAGCAGCTGCACCATTCGAAGGAGAAGCCGCACGAGTGCCGCATCTGCCACTATCGCTTCGAGTACGTCGGCCACCTGCAGCGGCACatccggcagcagcacgaaAAGATGGCGGAGGAGCTGCTGGCGCCGGCGGAACCGCAAACGTTCGATTGCAACTTTTGCGGCGAATCGTTCGACTCGAAACCTCTGCTAACGGCACACGTGCACACGTTGCACCGAGGCGAGAAGCCGTTCCAGTGTGACAAGTGTCCGGCTACGTTTAGCTATAAGAAATCTTACGAAACTCACCGAGAGGAACATTACTTGAAAGCCAGTAATGGAGCCTTCAAGTGCAGCTTCTGCAAGAAAACGTAA
Protein Sequence
MVLPQSDQPRKRSVKHVRFVEPNEENSYDGMRQTRGNVVSPHPLGLGQRTDDNEQDEEEDDEEEDEEEDEEGGEEEEEEEDDMDGLSLMQNLPPVESLLVEMDEPLEEENDDEEVEMEDDDDNGSRRRLSGRRGRRGGHHLSGLHRPGRPPKHSESIELELEPLLPEIEMSEGGGGGLGGASGTGDEKGDEQQRIPPVAHVCRVCLCDEKPAGEDGEVRPMESLYCTVVPEYQSRSLYSILVAVCHPLHLGSNAGMPDRICAPCKTKLLAAYELYDMCLRNDEMLRRKYQEKLLLASSAAGGGGEMRRIKKEKLDNNGVDALGGDHDDEDDYYRGGMPKRGSMRVNDHDDTYLYDRQYPLHSASAVAGRNSTIAALQSRFQHQQQPSHGRWGKYQRHQSQLHQVANGPEALRQLHDGRMKQAGAGGGAARSAANYDYNAFHRVLPNGSHQCTKCMREFKYHSYYKNHYISQHDPSKPFKCRKCHYTFLTERWLIVHMRTHIAAGDLMPLAGGPAAAAATQGAADAGAVDSFDSSLDGSVERRKGARGFDCYYCDMTFPAIALQKRHMLSVHADKHRGLECPICQCRFANQSSFLIHLKEHKEQKRLRNSSGGKQEEAGGKGEDAAAGSAAVKREYGCSVCAVTFAREVLLNEHLHEQHPDAFLAQNSDLAYMCGVCLAEFSDRAALEGHTSSTHTEAELAEAAAAAAKEKVQPPAAESESTGSQQGDVKKEGEQEGEEEEEEEEADDEQNEQNNADDGVKQQQQQQQQEEAAGEEETKGAEKPPEGCSLVYKCKLCQSRFVTKQSLATHLETHVAAMKRAAGKRPYSETGDGEGGDGAEGAGGADEDDYSGEDDDEEEEYGGSQNAGGEKRPKRAKPQAAEEDDDTTTEEMPIDPDEISFNPDTGEQMFTCQVCGKVINTVSQFRRHKRVHSPKGRPFECHICFYRFAMKYSYTAHMLRHELGCNPTQPTTYRCTKCSETFTRRKLLSQHMAAMHGRWSDGGSPMYGSPGQPGSTSGRGTHTCPICSESFTRESVLNGHMKTHNLEAAQLQHSEVCYLCRVCSNEYESREQYEAHAAEAHPGMKMEMVEAGVSADVLQKLGNVLDAAAAAATASQDGDGNAAVKTEEKRDNGAEGEEEERVGAGGDGGEEENGEQKSAASAAGGGFTLIFKCKLCSGRFLKKKTLDWHLQTHRSIAKQGDGVAILPDLGPDAIGDQPKMSKCTVCGQIFDNELLFHEHMRTHQRGPRPGVHLGYGGMAQQPPTRRRRTGGRSLIQCDLCKKTFMYRSQLHQHTMLHHQPGKPYECKICHYSFVHKLNLKRHELTHLREPPRQLLDQQQQQQQQDADQDDQLDNSHLLQPLVLMAGGTEEEATNGRGRGGGAAGTAQDDGGDGDQSGSAMDGSSAADDGTTGGSGRSWTAKKFKCVVCALVFNRQNELVVHLQTHIERINEVKNRTAAAVASAADAGIAPTDRQCKLCHKVFKFSCQLKQHHLLHHAREKPFECRTCHYRFEFKGHLVRHRANHHPNEAKEDQDFPSPYLTSTPLRGARGSGYGGEASSSSQGSGSVPKYGGMVTDDVIIAPTTSSPRSESGSAHQCPMCSLKFIKARSLAMHMRIHLGGRKLRRVIPASTAAPSPPGEAQPGTPTTGADKLVCRFCAGTFPTAHELKTHMMTHIGSEAMDLEVPFGISAFNLLHENMFNDSMGGEGGSSAGALGGEDHSSMGGEGGSNSRAEGGSTDGDYQQDDGEDGSGGDPLFDGSNLELVLEDNILDKDFGMRYQQQQQQQQQQQQKRRSGKSGQNNGDGGDDAGEEEEDDDEENEDDVTDTNDGDGGAGEDDEEEDEGEQSSASTMASFQRHMNLMATHRSRLAATAALSARLQATPSASSSSQSSSSAKGKIVCELCKKEFLYPCNLNQHKQLHHSKEKPHECRICHYRFEYVGHLQRHIRQQHEKMAEELLAPAEPQTFDCNFCGESFDSKPLLTAHVHTLHRGEKPFQCDKCPATFSYKKSYETHREEHYLKASNGAFKCSFCKKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
iTF_00107126; iTF_00104543; iTF_00093607; iTF_00101102;
80% Identity
-