Basic Information

Insect: Anopheles gambiae
Gene Symbol: ZFY
Assembly: GCF_000005575.2
Location: NT:39539755-39542531[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 3 1.5e+02 2.6 2.0 1 15 48 62 48 65 0.83

2 13 9e-05 0.0046 16.9 1.1 2 23 349 370 348 370 0.97

3 13 1e-05 0.00052 19.8 0.6 2 23 377 398 376 398 0.97

4 13 0.016 0.83 9.8 0.6 1 23 408 430 408 430 0.97

5 13 1.9 94 3.3 0.1 3 23 455 482 453 482 0.78

6 13 8.7 4.4e+02 1.2 1.1 2 20 489 507 488 510 0.64

7 13 4.9e-07 2.5e-05 24.0 2.7 1 23 548 571 548 571 0.96

8 13 0.0024 0.12 12.3 1.1 2 23 577 598 576 598 0.95

9 13 2e-05 0.001 18.9 2.2 1 23 603 625 603 625 0.94

10 13 0.0055 0.28 11.2 0.1 2 23 634 656 633 656 0.97

11 13 0.0003 0.015 15.2 0.5 2 20 663 681 662 683 0.93

12 13 4.5e-05 0.0023 17.8 0.4 1 23 694 716 694 716 0.99

13 13 0.00048 0.024 14.6 2.6 1 23 722 745 722 745 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	3	1.5e+02	2.6	2.0	1	15	48	62	48	65	0.83
2	13	9e-05	0.0046	16.9	1.1	2	23	349	370	348	370	0.97
3	13	1e-05	0.00052	19.8	0.6	2	23	377	398	376	398	0.97
4	13	0.016	0.83	9.8	0.6	1	23	408	430	408	430	0.97
5	13	1.9	94	3.3	0.1	3	23	455	482	453	482	0.78
6	13	8.7	4.4e+02	1.2	1.1	2	20	489	507	488	510	0.64
7	13	4.9e-07	2.5e-05	24.0	2.7	1	23	548	571	548	571	0.96
8	13	0.0024	0.12	12.3	1.1	2	23	577	598	576	598	0.95
9	13	2e-05	0.001	18.9	2.2	1	23	603	625	603	625	0.94
10	13	0.0055	0.28	11.2	0.1	2	23	634	656	633	656	0.97
11	13	0.0003	0.015	15.2	0.5	2	20	663	681	662	683	0.93
12	13	4.5e-05	0.0023	17.8	0.4	1	23	694	716	694	716	0.99
13	13	0.00048	0.024	14.6	2.6	1	23	722	745	722	745	0.98

Sequence Information

Coding Sequence: ATGGAACAGTTTGTAAATTGCGTACTGTGCTTGACTACCGAGCCGCAAAGCTTTCTCAAGGTGTACAATGAAGAGAAACAGGATACAGACATCGCGTCCGTAATAACAAAACATCTTTGGGTGAAACCGGCCAAGGATTCGTACGTATGTGATGAGTGCTGGAAATGTTTAAACGATTTCCACGAGTTCTACACCAAGCTCGAGAACATACACTATCCGCCCgatccggaggatgcgtcatGCAATGCCAAAGACATCCGACAGTACCTTTTCGAATTTCATCCCGTGGAAGACGTGAAGATCGAGGAACTGTCTCAGAATGCGGAGGACATGGAAGAAATAGAGTACGAGTATTTGGAAGCATGTAACGAAGAAACCATAGAGAATGAGAACGCCGAACGTTCCAGCGGTCGTCCGAAACGAGCCAGTGCCGCACAGGCGAACTATAAAATTGAAGCGGCCGAATCGGAGTGGGAAAAGGATTACCTTGCGACCAACGAGGACGagtacgacgacgacgacgacgacgacgacgaagcgGACGCCGATTACAATGGCGATGAGAAGGAAGAGGTTGACTATCTGGAAGAGGATAATGATGACAGTGAGGTCATTAACTACGATAGTCCCTCGAAGGCAAAGCAAGAGCCGGGCACCAAAAAGGAGCCAGCCAGCGAACCGACGTCACCACCGAAAAGGGGTAGAGGTAGGCCTCCGAAGGCAAAACCCGAGATCGAAATCAAACCGGAACCGAAATCAAAGCTGCGCCGCCGGGGTCGTAAAAGAAAGGTTTCGGTTAGCAGCAGCGACTCGGAGCTGGAATCCGACTTTGACGATTTTATTGACGGCGAAGACTGGAAGAAGTATCGCAACACGTCGAAGGATAAGGGGAGAAGGTCGCTCGGTTTTCGGCAGCTGCAGGAAAAGATATTTTCATACGTGGATGAATTTATCTGCTACTACTGTCCGGAAAAAATCGTCTTCGAACGGTTTCACCATGCGAATTTGCATTACAAGAAGGTACATAATGAGCCAGCCTTTCTGCGGTGTCCAAAGTGTGGCAAAAAGTGCTTCACACCGGGCGGATTTGTGAGCCACATGGAAACGCACGAAGATCCGGAGCGGAACAAGTGTAAAATCTGCGGCAAGGTTACGGATCAGGAAATCACGCTCAAGAAGCACATGCGAGCGCACCAGGAGAACCTGGAGAAGGACTTTCCGTACCCGTGCAGCCTGTGCAATCGGCGgttcgaggaggaggagaagcgAGAGAAACACGAACGGCTGCACGGACGGAAATTGATCATCAAGAAGGAGAAGGGTCGCGATCTGGAGCTGCTTGAGTTCTACAAACGCATCTACTGTGAAGTGTGTGAAGAGAAAAAGCCCGAATCAACCTCGTTCGATAACTTCTGGGATCTGAAGGTGCACATGGGTAATGAGCACAACAAAACGCCATTCCTAAAGTGTCCAATCTGCTTCAAGAAGAATGTGTGCCGCCAGCAGCTAATGGTGCACGTGGATGTACATAATAATCCAGAAAACTATCGcTGTGAGGTGTGTAAGGAAATCCATCAGAATCTTGAAAAGCACATGATAAAAGCACACACCCCGGAAACGTCGTTACCGGACGAGAAAAATTACAGCTGCGAACATTGCGGAAAGATGTTCAAATATCAAACGAATCTTAAAAGTCATATCGATCGTGTCCACGGTGTAAAGGATGTATCCTGTGACATCTGCCACAAATATTTCAATAGCAAAGCATTGAGCGCTCACAAACGTTCAGCCCACACGGACGAGATGTTTATGTGCGAACATTGTCCGAAAATGTTCAAAACGCGCAGCGGTCTCGAATCCCACAAGAGTGACCACGACGAAACGTTACGCAAATCGGTGCAGTGTCTCATCTGTGGCAAGGAGATGCGCCGCGGTGCCAGCATGGCGAAGCACATGAAAACGATCCACTCGCAGGAGGATCCGGTCAGCTGTGATCTATGCGGCAAGGTGTTCCGCACCACGTTCCACATGATGCGGCACCGCGCCAACACGTGCTCGGCCACGATCGACTCACGGCCGTACAAGTGCGAAGTGTGCGGCAAAGGCTTTGCCATGAAGCTCACGATGACCGAGCATATGACAACGCACACGCGCACAAGCCTGTATCAGTGCGCGTTCTGCTTCAAGACCTTCGGGTACATTTCGAATCTGTACAAACACCGAAAGAAGGCTCATCCGCTCGAATGGCAGGAGGTGCAGGCACGGCCTGAACAGGGAATTGCCACCGTAATCGAAATACGCAATTAG
Protein Sequence: MEQFVNCVLCLTTEPQSFLKVYNEEKQDTDIASVITKHLWVKPAKDSYVCDECWKCLNDFHEFYTKLENIHYPPDPEDASCNAKDIRQYLFEFHPVEDVKIEELSQNAEDMEEIEYEYLEACNEETIENENAERSSGRPKRASAAQANYKIEAAESEWEKDYLATNEDEYDDDDDDDDEADADYNGDEKEEVDYLEEDNDDSEVINYDSPSKAKQEPGTKKEPASEPTSPPKRGRGRPPKAKPEIEIKPEPKSKLRRRGRKRKVSVSSSDSELESDFDDFIDGEDWKKYRNTSKDKGRRSLGFRQLQEKIFSYVDEFICYYCPEKIVFERFHHANLHYKKVHNEPAFLRCPKCGKKCFTPGGFVSHMETHEDPERNKCKICGKVTDQEITLKKHMRAHQENLEKDFPYPCSLCNRRFEEEEKREKHERLHGRKLIIKKEKGRDLELLEFYKRIYCEVCEEKKPESTSFDNFWDLKVHMGNEHNKTPFLKCPICFKKNVCRQQLMVHVDVHNNPENYRCEVCKEIHQNLEKHMIKAHTPETSLPDEKNYSCEHCGKMFKYQTNLKSHIDRVHGVKDVSCDICHKYFNSKALSAHKRSAHTDEMFMCEHCPKMFKTRSGLESHKSDHDETLRKSVQCLICGKEMRRGASMAKHMKTIHSQEDPVSCDLCGKVFRTTFHMMRHRANTCSATIDSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQEVQARPEQGIATVIEIRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00093670;
90% Identity: iTF_00093670;
80% Identity: -