Basic Information

Insect: Anopheles gambiae
Gene Symbol: -
Assembly: GCF_000005575.2
Location: NC:2158496-2166394[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.3 1.7e+02 2.5 0.0 2 23 4 25 3 25 0.95

2 14 0.31 16 5.7 2.9 1 21 1694 1714 1694 1717 0.93

3 14 0.017 0.86 9.7 0.9 1 23 1888 1910 1888 1910 0.97

4 14 0.00036 0.019 14.9 2.0 2 23 1913 1934 1912 1934 0.96

5 14 8e-05 0.0041 17.0 1.9 1 23 1940 1962 1940 1962 0.98

6 14 4e-05 0.002 18.0 3.5 2 23 1969 1991 1968 1991 0.96

7 14 0.0063 0.32 11.0 0.5 1 23 2001 2023 2001 2023 0.98

8 14 0.00016 0.0082 16.1 2.8 2 23 2029 2051 2028 2051 0.96

9 14 0.035 1.8 8.7 0.6 3 23 2065 2084 2064 2084 0.97

10 14 6.3e-05 0.0032 17.3 0.9 1 20 2091 2110 2091 2113 0.92

11 14 0.001 0.053 13.5 0.2 1 23 2121 2143 2121 2143 0.97

12 14 0.0001 0.0051 16.7 3.1 1 23 2149 2171 2149 2171 0.98

13 14 0.00054 0.027 14.4 5.8 1 23 2177 2199 2177 2199 0.98

14 14 0.0035 0.18 11.9 3.5 1 23 2205 2227 2205 2228 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.3	1.7e+02	2.5	0.0	2	23	4	25	3	25	0.95
2	14	0.31	16	5.7	2.9	1	21	1694	1714	1694	1717	0.93
3	14	0.017	0.86	9.7	0.9	1	23	1888	1910	1888	1910	0.97
4	14	0.00036	0.019	14.9	2.0	2	23	1913	1934	1912	1934	0.96
5	14	8e-05	0.0041	17.0	1.9	1	23	1940	1962	1940	1962	0.98
6	14	4e-05	0.002	18.0	3.5	2	23	1969	1991	1968	1991	0.96
7	14	0.0063	0.32	11.0	0.5	1	23	2001	2023	2001	2023	0.98
8	14	0.00016	0.0082	16.1	2.8	2	23	2029	2051	2028	2051	0.96
9	14	0.035	1.8	8.7	0.6	3	23	2065	2084	2064	2084	0.97
10	14	6.3e-05	0.0032	17.3	0.9	1	20	2091	2110	2091	2113	0.92
11	14	0.001	0.053	13.5	0.2	1	23	2121	2143	2121	2143	0.97
12	14	0.0001	0.0051	16.7	3.1	1	23	2149	2171	2149	2171	0.98
13	14	0.00054	0.027	14.4	5.8	1	23	2177	2199	2177	2199	0.98
14	14	0.0035	0.18	11.9	3.5	1	23	2205	2227	2205	2228	0.95

Sequence Information

Coding Sequence: ATGGCGATCGAATGTCCGGTCTGTACGCTGTACCTTCGGTCCGGCATGACGCTGGCCGAACATTTGGACACGCACCCGAAGGAGAACGTGATCAAGGCGCTGGTGAGCATGGTCAAGCCCGACAGTCTCCCTTCCTTCGGCGGCGAGCCGGTGGAGGAGCTGGGCACGGCGAGCGAGCCCGTTCCGGCGGAGGGTGGCAGCACCGCGGCGCTCCACGGGCAGCCGGGCccgagcaccagcagcacaagTGCCAGCGGCAGCAACACGATCTCATTTCGTCCGAACGATCGGACCTCGGCGTCCGTGGGGATTTTTGAGGCACAGCCGTCACTGTTTCTGGACAATGCGCTGATAGCAACGTCGGCCactagtagcagcagtagcagcagcagcagcagcagcagcactaccaCTCCCGCCACTGTACAAGTCAACCTTACCTCCAGCCAGGCACCGCAGGTCACCGTGGTGAAGAAGATCGATGTGCACGgtgtgccgtgctttcaggTAAACAATGTGACGCTGGTCAAGCGGGAGCTGGTACAGccagtcgcagcagcagcgccggcaccaccaccccctccaccaccaccaccagcagcactgcCAGCGCCGTCTGTCGCCACTGTCGGAACGGTGCCGAACGAGCTGGCGGCGATTGGGCCACTGGGCGACGAGTACACCGAGCCGAGCGGGAGTGGCACGGCGGCCGGCGGCAGCTCGTCCCGCGTCGTCTACCCGCGGTACACGAACGAGCTGTACTCGGGCCCACCGCCCCCGTACAGTCGCGCCATCTCGTCCACGGTGGCTTCCAGCACGCAGATCACgcccgtgcagcagcagcagcagcagcagcaaacgttgCAGCTGAGCATCACGAAGAGCAGCGTCGGCGGGCTCGGTGTGGTGGGCCAGCAGATTCAGCTGCTGGCGAAAAACCTGTCCGAGGCGTCGGTGTCCGCGTTCAAGCAGTACCCGGCCTCGGCAGTGCAAACCGTGTCCGTGCTGGACCGGGGCAGCCACGAGGAGCCAGCGGCAGCAACGGCGAGCGTCGCCTCGCCGTCGGCACCGGTCGGCACCCCGAAGCTGCTGTACAGTGTGGCGACAACGGCGGGCCCAAGAACGGCCGGGACTGCAATAacgtccaccaccaccacgaccgcCGCCAACACGCCGAGCGCCAGCACCGCCCTGGTCGACCATCTGGCAACGGGTGTCCCGacgatcaccaccaccaccggcggtACCAAAACGACCGTCTCGGCGTCCCCGTCCTCGTCCAAGTCGAACGTGGTGAAGGTGCTGAGCAACGTGAAGGTGCACACCGATCTGAAGGACTTCCAGGACATCATCATGCACCTGAACGCGGGCCAGATGTCGATCGTCGGCGACAAAACGTCCCTGATACCGCCCGTCACCGAGCGGCGCCCGTCGGCGTTCGCGGCGAGCACACCGGGCCGTTCCCTGCTCGCGATAACGCCGGCGAAGAGCGAGCTCCCggcggagcagcagcatcagcagcagcagcaacaaccgcTCTGTAACACCGGCATGCCGACGACCAAGAGCGAGGTAGAGGACTTGACCGGCGATTATGATCACGAGGTGGAGTACAGTGGCAGCTGGCAGGAGATGGACGACCATTATGCCGACGGTGAGGTGCGCAGCCAGCAGTGGGAGGGCGAGGAAGAAGAGGGTGCGGGCGGAAGCAGCAAGCGGTTCCGTAGCGCTAGCGAGCAGCGGGAAACGCTGCCGGCGGCCGCCGCATCGCTGGACGAGCGGATGGCTCCTGGCGAAATGgcaaacggtggtggtggtgtggccTGCTCCAGCGGCAGTGCGATGGTCACGAGCGTCATCCGCAAGACGCCGCAGCCCGTGCCCTGTGCCCTGTCGCCACCCGCGCCCCAGCAGGAGTCGAAAGCGAACGTGAAGCGGCTGGTGTTTCGCGTGGCCGGCAACAGTGCCACCCCGACGACGGTTACGATATCGCCTGCGGGGCCTTCCAGCGCGCCGAAAATTGTGCGCGCCTGGCAGGGGATCAAGGTGGAGGAGGACGGCACGGAGCCAGCGTCGAGCAATGCGGACGGAATTGGTGGTGTGGCTGAACCGGATAGGGCAGCAAACGACGCAAGTGCAAtaaacgcagcagcagcagcagcagcaccgccaccTACAGCAACAGTCAGCACGAGTCTCGATTACGGCGCGATCAAGCAGAGGCGAGGGGGTTTCCGGCCCCCGAAAAAGTTAGCAATCAAACCGAAACGTACGTCGGTGGGGGAAGGCCCCGCGCCGTCCACCTCGGGGAAGCAGGGCGCACCGATGCAGGTGGACGAGGTCGAGCCGGCGCAACCGCCCGCACCGACAACGATGGTAATGGCCACCGCGCTTACCACGCTGGCGGATGTCGTGTGCACGACTGCTGCGGCCGCCCAGCACCTCACCGCGGAACCGTTTTGCTCGTCGTCGTTCAACGGCATCACCGCCGTAATTCAGAAGACTGAAGCAACCGCTCACGCGGGCCCGTACGCGAcggagcagcaacagcagcagcagcagcagcagcagcagcagcctaaCAGCTCGGCCGGGGACGGGATTGCCGACgcatatcatcatcatcatcatcatcatcaccagccCCCGGACCCCGTCATCAAGCAGGAATACTCGCAGCCGCACGCCATGCCAGCACCATCGgcgtcagcagcagcgggcaCACTTGCCTCCAGTTCGGCCGTGTACGGTGTGCGATCGTCGTACGGGCTCGTGCCGACCAGCACCGGCACTGCCTCCGCTCCTAGTTCGAGCGCACCGGGCGGCGTTCGCCTAATGCCACAGCACCGCCCATCGACCGAGATCGACGTCGGCGCGTACAACATCTCGTACGTTGGCGAGGCGGGCGAAACGATCTACCATCCGCTGCCGAAGCGCGATGGCAAAACGTTCGGGGCGCAGGAGTTGCTGCCGGCGGGCGGCAATGGGCTGGCGGCTGGGGGCGAGAGCGGTGCCGACGGTTCCACTGCCGCCCCGGCCCACCCGGACAGTCGCCGGATGGAAGtcgaggaggtggaggaggacgaggaggagctgGGAGAGGAGCAGATGGAGCTGGAAGAGGACGACGAGGATGCACCAGAGCttgaggaggaggatgaggaggaagaagaggacgaggaggaggaggaagatgaagacgatgaggacgatgaggaggaggaggagaaggagctggaggaggatTTGATCGACGATGAGGAAAAGGAAGCACATGAGCACGGCGAGCTCGtacaggaggaggaggaggaggaagaggtaCAGCTGGGTagcgacgaggaggaggaagaggatgatgatgaggaagaggaagaggaggaagaggatgaagaggaggaggaggaggacgagtacgatgatgacgatgtgTACGAGGTCGAGCCGCGGCCCGTCGCTGGCCGGTACGATGCGTCCTCCCAGCCGGAGGCGCACGGCCGTCGCCGATTGCTGATGGTGGTCAGCAAGCCTGCGACAGCCACCGTCACTGCATCGGAAGCGGCCGAACCGAACGGCCCGTACGAACGTCCTTTGCCGGTGGAGCCGGCGGCTGAGGTTGTGGCGAGCGGCAGCTTGGTGGTGAAGCGGCTACCGGCAGCCGTGCCCGGCACGCCGGACGACGAGAAGGATTTGCTGGAGGCGGGACCGTCCACCCGCATGCTCGAGCGGAGCGGCATTCCGCGGCCAAAGTTCCGCATCACCAATGCCGACCCGTTCCGGCCGACGGCAGGGCTGGAACCGGTGCGGAAGACGGAGGTGGACGCGGAGCCGGAGTACGAGTGCTCCGACAGCAAGGACTTTTTGGAGCAGAGCCTGGGCAGCAACCCTGCGGTCGGCGGTTCGACCGTGGCCGCGCACGAACAGATCCAAACGACGGGCGAGCCGCTGAAGGCGGCCAAAGCCGAACCGTGCCACGACGGGCAGGACGACGGGCAGGACACGTCCGCATCCTCGTTTCTTGATCTGAGCACGGTGCGGAAGGGTGGGCTGCCGGCAGGTCCTGTTACCACGgacacgagcagcagcaacagcagcagcaacagcagcaacagcagcagcagtcacaGCACCACAAACATCAGCCTCAGCCAGCACAGCCACAGCCAGCTGAGCCACCGTCACAGTCACAGCGCGGTGAGTGGTGGTTGCAAGGAGGGAGGCGAAGGGAGCGGCACGAGTGGCGGAACGCGCTCCCTGCTGTCGTCCGGTTCGTCGCACGCGTCCACCAGCATGGAGCGGGCACCCTCGACCGAGAGCTTGAACATCCGCACGGACGAAAAGATGCCGGCGAAGGGGGAAATTTCCGAGCAGGAAAGCAACGGCGACATGGACATGACGTCGTGGAACCATCGGATGTACGCCGTGGTCGAGAATATGCCCATCTATCCGAGCTCGTACGATTTATCGACCGCACAGGAGTGCTGGAATCTGAGCAGCCGCAATCAGGGCATCTTTGCCGTGACGGACCATttctaccagcagcagcagcagcagcagcagcagcagcaacagcagcagcaacaacacaacagtGGTAGTAATAATAACTCACACGGCACCACGGTCAACGGCCAGTACATGACGTCACGCGTTGCTTTCCAATTTTCCTCAACCGGTCATCAaaacctgcagcagcagcagcaccagcagcacggtTCGGCCGATGCGCCCTTGGATGGCGGTATGATGCAGGCGAGCAAGATCGAACCGCCGATGGATGTGGACAGCGATAGCGGGGAGGTGATGCCGAAGCTGCCGTTTGCGGACATGATGGTAGCGCGCATGCACGAGCCACCGGGTGCATACGATGAGGTGGGCAgcagccaccaccatcaccaccagcagcagcagcagcaacaaacgcTGCACCAGCCGTGTGAAGCCAAGTACGAGGAAACGATCGGTACGACGTCCTACTTTGGTGTTGCGACCTGCTCCGCCGTACCGGTGATGCAGCAGCCGACGGACGATCCCGTGCGGCCCAACCGACCGAAACCGTCCGGCAGCGGTGTCGCGCGCACCTACCGCTGTACGCTCTGCGCCAAGGTGTTCAGCTCGATCAAGCAACGGCGGCTGCACCAGCAGTGCGAGCACGTGGACGATCTGGTGGCACTGTCCTCGTCGCACCAGCAGGAGATGCGCGGCGAGGAGGACAATAAGCCGCTAATGGATGGcagacagcaacagcagttgccccagcagcagcaccagcagcagcagcagcagcagcagcagcagcagcagcaacagcaacaggcacagcaacagcagcaaatataCAAGAAGGCGCCGATTCCCGTGGTGATGAACTATCACTGGATGAAGCAGGAGATAGAGCGAAAGAGTGAGGCGGCGCTGCGTAGCAGCCGGTTGCTGATGGCGGGCAGCAGCGCTGGCAGCAGCACGACTGTCGTCCTGCCCGGCACGAGCAGCGGGGAGGCGGCAccgggccagcagcagcagcagcagctagtgCTAGAGCAGCACGTGCAGGTGCAGGTGCAGCTGCAGACCGACGGTGGAACCGTCGCGGCGTTGAGCGCGTCCGCTGAGAGCGCGCTGCTGCCGGCGGCTCACTGCTCGGTAGCGGCACGCAACCGTTCGTACGTGTGCAGCACCTGCAGCCGGGAGTTCGACCGGTTCAACCTGTTCAACGAGCATCTGCTGGAGCATCCGGTGGAGTGTTCCGCGTGCGGGCGGCACTTCAAGCAGTGGCGCAACTTTTCGCTCCACATCAAGCGGCACCTCGGCATCAAGGAGCACCAGTGCCGGATGTGCGGCAAGCGGTTCGTCATCAAGCAGAAGCTGATCGAGCACATGCGGGTGCACACGGGGCACGCGCCGATCAAGTGCAAGCTGTGCAACCGGACGTTCAAGCGGTTCTCCAACCTGGCCCAGCACCGGAAGCGCTACCATCTGAACCGCACCGTCGTGAAGGAGGAGTACGTGTGCCAGCTGTGCGGCGAGGTGTTCCACACGATGGCCAAGATGGAGTGGCACAAGGAGACGCACGAGAAGAAGCCAAAATCGTGCCCGTACTGTCGGGAGAAGttcatacaccgcaacagcttGACGCGCCACATCCGGCTGTCCCACACGGACAAGTACGCGAAGCTGGAGAACAAAACCGAACCGTGCAGCATCTGCCAGCAGCCGTACACGAAGACGAGCATGCGGCGCCACCTGGAGACGCACACCAAGGAGCGGATGGCGTACGCGTGCGGCATCTGCAACAAGCGGTTCACCACCAACTGGAACCTGAAGCAGCACAAGTGGACGCACACGAACCCGACGATGAAACCGTTCCAGTGCACGTACTGCCCGAGCGCGTTCGTGCGCGAGTCGGACTTTGTCACGCACGTCAATGCGCACCGGTCGATCCGGCCGTACACGTGCAATCACTGTGGCAGCCAGTTCATCCGGAAGTACAACTGGATCCGGCACACGCGCGAGCACGAGATCGACAAGGGGCACCGGTGCGACGTGTGCGGCCGCCAGTTCCACCGGAAGTACTACCTGACCGAGCACAAGCGCATCCACACGGGCGAGCGGCCGTTCGCGTGCAACATCTGCGGCAAGACGTCCGCGACCAAGACGAACCACAACAAGCACGTGCGGATACATCACGCGCGCGACCCGCTCACGGCGGAAGGGTAA
Protein Sequence: MAIECPVCTLYLRSGMTLAEHLDTHPKENVIKALVSMVKPDSLPSFGGEPVEELGTASEPVPAEGGSTAALHGQPGPSTSSTSASGSNTISFRPNDRTSASVGIFEAQPSLFLDNALIATSATSSSSSSSSSSSSTTTPATVQVNLTSSQAPQVTVVKKIDVHGVPCFQVNNVTLVKRELVQPVAAAAPAPPPPPPPPPAALPAPSVATVGTVPNELAAIGPLGDEYTEPSGSGTAAGGSSSRVVYPRYTNELYSGPPPPYSRAISSTVASSTQITPVQQQQQQQQTLQLSITKSSVGGLGVVGQQIQLLAKNLSEASVSAFKQYPASAVQTVSVLDRGSHEEPAAATASVASPSAPVGTPKLLYSVATTAGPRTAGTAITSTTTTTAANTPSASTALVDHLATGVPTITTTTGGTKTTVSASPSSSKSNVVKVLSNVKVHTDLKDFQDIIMHLNAGQMSIVGDKTSLIPPVTERRPSAFAASTPGRSLLAITPAKSELPAEQQHQQQQQQPLCNTGMPTTKSEVEDLTGDYDHEVEYSGSWQEMDDHYADGEVRSQQWEGEEEEGAGGSSKRFRSASEQRETLPAAAASLDERMAPGEMANGGGGVACSSGSAMVTSVIRKTPQPVPCALSPPAPQQESKANVKRLVFRVAGNSATPTTVTISPAGPSSAPKIVRAWQGIKVEEDGTEPASSNADGIGGVAEPDRAANDASAINAAAAAAAPPPTATVSTSLDYGAIKQRRGGFRPPKKLAIKPKRTSVGEGPAPSTSGKQGAPMQVDEVEPAQPPAPTTMVMATALTTLADVVCTTAAAAQHLTAEPFCSSSFNGITAVIQKTEATAHAGPYATEQQQQQQQQQQQQPNSSAGDGIADAYHHHHHHHHQPPDPVIKQEYSQPHAMPAPSASAAAGTLASSSAVYGVRSSYGLVPTSTGTASAPSSSAPGGVRLMPQHRPSTEIDVGAYNISYVGEAGETIYHPLPKRDGKTFGAQELLPAGGNGLAAGGESGADGSTAAPAHPDSRRMEVEEVEEDEEELGEEQMELEEDDEDAPELEEEDEEEEEDEEEEEDEDDEDDEEEEEKELEEDLIDDEEKEAHEHGELVQEEEEEEEVQLGSDEEEEEDDDEEEEEEEEDEEEEEEDEYDDDDVYEVEPRPVAGRYDASSQPEAHGRRRLLMVVSKPATATVTASEAAEPNGPYERPLPVEPAAEVVASGSLVVKRLPAAVPGTPDDEKDLLEAGPSTRMLERSGIPRPKFRITNADPFRPTAGLEPVRKTEVDAEPEYECSDSKDFLEQSLGSNPAVGGSTVAAHEQIQTTGEPLKAAKAEPCHDGQDDGQDTSASSFLDLSTVRKGGLPAGPVTTDTSSSNSSSNSSNSSSSHSTTNISLSQHSHSQLSHRHSHSAVSGGCKEGGEGSGTSGGTRSLLSSGSSHASTSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMDMTSWNHRMYAVVENMPIYPSSYDLSTAQECWNLSSRNQGIFAVTDHFYQQQQQQQQQQQQQQQQHNSGSNNNSHGTTVNGQYMTSRVAFQFSSTGHQNLQQQQHQQHGSADAPLDGGMMQASKIEPPMDVDSDSGEVMPKLPFADMMVARMHEPPGAYDEVGSSHHHHHQQQQQQQTLHQPCEAKYEETIGTTSYFGVATCSAVPVMQQPTDDPVRPNRPKPSGSGVARTYRCTLCAKVFSSIKQRRLHQQCEHVDDLVALSSSHQQEMRGEEDNKPLMDGRQQQQLPQQQHQQQQQQQQQQQQQQQQAQQQQQIYKKAPIPVVMNYHWMKQEIERKSEAALRSSRLLMAGSSAGSSTTVVLPGTSSGEAAPGQQQQQQLVLEQHVQVQVQLQTDGGTVAALSASAESALLPAAHCSVAARNRSYVCSTCSREFDRFNLFNEHLLEHPVECSACGRHFKQWRNFSLHIKRHLGIKEHQCRMCGKRFVIKQKLIEHMRVHTGHAPIKCKLCNRTFKRFSNLAQHRKRYHLNRTVVKEEYVCQLCGEVFHTMAKMEWHKETHEKKPKSCPYCREKFIHRNSLTRHIRLSHTDKYAKLENKTEPCSICQQPYTKTSMRRHLETHTKERMAYACGICNKRFTTNWNLKQHKWTHTNPTMKPFQCTYCPSAFVRESDFVTHVNAHRSIRPYTCNHCGSQFIRKYNWIRHTREHEIDKGHRCDVCGRQFHRKYYLTEHKRIHTGERPFACNICGKTSATKTNHNKHVRIHHARDPLTAEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00093640;
90% Identity: iTF_00093640;
80% Identity: -