Basic Information

Insect: Anopheles arabiensis
Gene Symbol: -
Assembly: GCA_016920715.1
Location: NC:14422609-14436627[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.4 1.6e+02 2.5 0.0 2 23 4 25 3 25 0.95

2 14 0.32 15 5.8 2.9 1 21 1688 1708 1688 1711 0.93

3 14 0.017 0.83 9.7 0.9 1 23 1869 1891 1869 1891 0.97

4 14 0.00038 0.018 15.0 2.0 2 23 1894 1915 1893 1915 0.96

5 14 8.2e-05 0.0039 17.0 1.9 1 23 1921 1943 1921 1943 0.98

6 14 4.1e-05 0.002 18.0 3.5 2 23 1950 1972 1949 1972 0.96

7 14 0.0065 0.31 11.1 0.5 1 23 1982 2004 1982 2004 0.98

8 14 0.00017 0.008 16.1 2.8 2 23 2010 2032 2009 2032 0.96

9 14 0.036 1.7 8.7 0.6 3 23 2046 2065 2045 2065 0.97

10 14 6.5e-05 0.0031 17.4 0.9 1 20 2072 2091 2072 2094 0.92

11 14 0.0011 0.051 13.5 0.2 1 23 2102 2124 2102 2124 0.97

12 14 0.0001 0.0049 16.7 3.1 1 23 2130 2152 2130 2152 0.98

13 14 0.00056 0.027 14.4 5.8 1 23 2158 2180 2158 2180 0.98

14 14 0.0036 0.17 11.9 3.5 1 23 2186 2208 2186 2209 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.4	1.6e+02	2.5	0.0	2	23	4	25	3	25	0.95
2	14	0.32	15	5.8	2.9	1	21	1688	1708	1688	1711	0.93
3	14	0.017	0.83	9.7	0.9	1	23	1869	1891	1869	1891	0.97
4	14	0.00038	0.018	15.0	2.0	2	23	1894	1915	1893	1915	0.96
5	14	8.2e-05	0.0039	17.0	1.9	1	23	1921	1943	1921	1943	0.98
6	14	4.1e-05	0.002	18.0	3.5	2	23	1950	1972	1949	1972	0.96
7	14	0.0065	0.31	11.1	0.5	1	23	1982	2004	1982	2004	0.98
8	14	0.00017	0.008	16.1	2.8	2	23	2010	2032	2009	2032	0.96
9	14	0.036	1.7	8.7	0.6	3	23	2046	2065	2045	2065	0.97
10	14	6.5e-05	0.0031	17.4	0.9	1	20	2072	2091	2072	2094	0.92
11	14	0.0011	0.051	13.5	0.2	1	23	2102	2124	2102	2124	0.97
12	14	0.0001	0.0049	16.7	3.1	1	23	2130	2152	2130	2152	0.98
13	14	0.00056	0.027	14.4	5.8	1	23	2158	2180	2158	2180	0.98
14	14	0.0036	0.17	11.9	3.5	1	23	2186	2208	2186	2209	0.95

Sequence Information

Coding Sequence: ATGGCGATCGAATGTCCGGTCTGTACGCTGTACCTTCGATCCGGCATGACGCTGGCCGAACATTTGGACACGCACCCGAAGGAGAACGTGATCAAGGCGCTGGTGAGCATGGTCAAGCCCGACAGCCTCCCTCCCTTCGGCAGCGGGCCGGTGGAGGAGCCGGGCACGGCGAGCGAACCCGTGCCGGCGGAGGGTGGCAGCACCGCGGCGCTCCACGGGCAGCCGGGCccgagcaccagcagcacaggtgccagcagcagcaacgcgaTCTCATTTCGCCCGAACGAGCGGACCTCGGCGTCCGTGGGGATTTTTGAGGCGCAGCCGTCACTGTTCCTGGACAGTGCGCTGATAGCAACGTCGGCCAcaagtagcagcagtagcaccagcagcagcagcagcagcagcagcagcactaccaCCCCCGCCACTGTACAAGTCAACCTTACCTCCAGCCAGGCACCGCAGGTCACCGTGGTGAAGAAGATCGATGTGCACGgtgtgccgtgctttcaggTAAACAATGTGACGCTGGTCAAGCGGGAGCTGGTACAGccagtcgcagcagcagcgccaccaccccctccaccaccaccaccagcactgccAGCGCCGTCTGTCGCCACTGTCGGAACGGTGCCGAACGAGCTGGCGGCGATTGGGCCACTGGGCGACGAGTTCACCGAGCCGAGCGGGAGTGGTAGCTCGTCCCGCGTGGTCTACCCTCGGTACACGAACGAGCTGTACTCGGGCCCACCGCCCCCGTACAGTCGCGCCATCTCGTCCACGGTGGCTTCCAGCACGCAGATCACgcccgtgcagcagcagcagcagcagcaaacgttgCAGCTGAGCATCACGAAGAGCAGCGTCGGCGGGCTCGGTGTGGTGGGCCAGCAGATTCAGCTGCTGGCGAAAAACCTGTCCGAGGCGTCGGTGTCCGCGTTCAAGCAGTACCCGGCCTCGGCAGTGCAAACCGTGTCCGTGCTGGACCGAGGCAGCCACGAGGAGCCAGCGGTAGCAACGGCGAGCGTCGCCTCGCCGTCGGCACCGGTCGGCACCCCGAAGCTGCTGTACAGTGTGGCGACAACGGCGGGCCCAAGAACGGCCGGGACTGCAATaacatccaccaccaccaccaccacgaccaccgcCAACACGCCGAGCGCCAGCACCGCCCTGGTCGACCATCTGGCGACGGGTGTCCCGacgatcaccaccaccaccaccaccggcggtACCAAAACGACCGTCTCGACGCCCCCGTCCTCGTCCAAGTCGAACGTGGTGAAGGTGCTGAGCAATGTGAAGGTGCACACCGATCTGAAGGACTTCCAGGACATCATCATGCACCTGAACGCGGGCCAGATGTCGATCGTCGGCGACAAAACGTCCCTGATACCGCCCGTCACCGAGCGGCGCCCGTCTGCGTTCGCGGCAAGCACACCGGGCCGTTCCCTGCTCGCGATAACGCCGGCGAAGAGCGAGCTCCcggtggagcagcagcagcagcagcagcaatcgctCTGTAACGCCGGCATGCCGACGACCAAGAGCGAGATAGAGGACTTGACCGGCGATTACGATCACGAGGTGGAGTACAGTGGCAGCTGGCAGGAGATGGACGACCATTACGCCGACGGCGAGGTGCGCGGCCAGCAGTGGGAGGGCGAGGAAGAGGAGGGTGCGGGCGGAAGCGGCAAGCGGTTCCGTAGCGCTAGCGAGCAGCGGGAAACGCTGCCGGCGGCAGCCGCATCGCTGGACGAGCGGATGGCTCCGGGCGAAATGATGGcaaccggtggtggtggtgcggccTGCTCCAGCGGCAGTGCGATGGTCACGAGCGTCATCCGCAAGACGCCGCAGCCCGTGCCCTGTGCCCTGTCGCCACCCGCGCCCCAGCAGGAATCGAAAGCGAACGTGAAGCGGCTGGTGTTTCGTGTGGCCGGCAACAGTGCCACCCCGACGACGGTTACGATATCGCCTGCGGGGCCTTCCAGTGCGCCGAAAATTGTGCGCGCCTGGCAGGGGATCAAGGTGGAGGAGGACGGCACGGAGCCAGCGTCGAGCAATGCGGGCGGAATTGGTGGTGTGGTTGAGCCGGAAAGGGCAGCAAACGACGCAAGTGCAAtaaacgcagcagcagcagcagcaccgccaccTATAGCAACAGCCAGCACGAGTCTCGATTACGGCGCGATCAAGCAGAAGCGAGGCGGTTTCCGGCCGCCGAAAAAGTTAGCAATCAAACCGAAACGCTCGTCGGTGGGGGAAGGCCCCGCGCCGTCCACCTCGGGGAAGCAGGGCGCCCCGATGCAGGTAGACGAGACCGAGCCGGCGCAACCGCCCGCACCGACAACGATGGTAATGGCCACCGCGCTTACCACGCTGGCGGATGTCGTGTGCACGACTGCTGCGGCCGGCCAGCACCTCACCGCGGAACCGTTTTGCTCCTCGTCGTCGTTCAACGGCATCACCGCCGTAATTCAGAAGACTGAAGCAACTGCTCACCCCAGCCCGTACGCGacggagcagcaacagcaacagcagcagcagcctaaCAGCTCGGCCGGGGACGGGATTGCCGACgcatatcatcatcatcctcaccaCCAGCCGCCGGACCCCGTCATCAAGCAGGAATACTCGCAGCCGCACGCCATGCCAGCACCAtcggcgtcagcagcagcgggtACACTTGCCTCCAGTTCGTCCGTGTACGGTGTGCGATCGTCGTACGGGCTCGTGCCGACCAGCACCGGCACTGCCTCCGCTCCTAGTTCGAGCACGCCGGCCGCCGTTCGCCTAATGCCACAGCACCGCCCATCGACCGAGATCGACGTCGGCGCGTACAACATCTCGTACGTTGGCGAGGCGGGCGAAACGATCTACCATCCGCTGCCGAAGCGCGATGGCAAAGCGTTCGGGGCGCAGGAGCTGCTGCCGGTGGGTGGCAATGGGCTGGCGGTTGGGGGCGAGAGCGTTGCCGATGGTTCCACTGCCGCCCCGGCCCACCCGGACAGTCGCCGGATGGAAGtcgaggaggtggaggaggacgaggaggaggagctggGAGAGGAGCAGATGGAGCTCGAAGAGGATGATGAGGATGCACCAGAGctcgaggaggaggatgaggaggaagaagaggacgaggaggaggaagatgaagacgatgaggacgatgaggaggaggaggagaaggagctggaggaggatttgatcgacgaggaggaaaaggaggcaCATGTGCACGGCGAGCTCggacaggaggaggaggaggaggaagaggtaCAGCTGGGAagcgacgaggaggaggaggaggatgatgatgaggaagaggaagaggaggaagaggatgaagaggaggaggaggaggacgagtacgatgatgacgatgtgtACGAGGTCGAGCCGCGGCCCGTCGCTGGCCGGTACGAGCGGGTCGATGCGTCCTCCCAGCCGGAGCCGCACGGCCGTCGCCGTTTGCTGATGGTGGTCAGCAAGCCTGCGACCGCCACCGTCACTGCAGCGGAAGCGGCCGAATCGAACGGCCCGTACGAACGTCCTCTGCCGGTGGACCCAGTGGCTGAGGTTGTGGCGAGCGGCAGCTTGGTGGTGAAGCGGCTACCGGCACCCGTGCCCGGCACGCCGGACGACGAGAAGGATTTGCTGGAGGCGGGACCGTCCACCCGCATGCTTGAACGGAGCGGCATTCCGCGACCAAAGTTTCGCATCACCAACGCCGACCCGTTCCGGCCGGCGGCAGGGCTGGAACCGGTGCGCAAGACGGAGGTGGACGCGGAGCCGGAGTACGAGTGCTCCGACAGCAAGGACTTTTTGGAGCAGAGCCTGGGCAGCAACCCGGCCGTCGGCGGTACGACCGTGGCCGCGCACGAACAGATCCAAACGACGGGCGGGCCGCTGGTTGCGCTGAAGGCGGCCAAAGCCGAACCGTGCCACGACGGGCAGGACGACGGACAGGACACGTCCGCATCCTCGTTTCTCGACCTGAGCACGGTGCGGAAGGGTGGGCTGCCCCCGGGCCCCGTTACCACGGatacgagcagcagcaacagcagcagcaacagtagcaacagtagcagcagccacagcaccACAAACATCAGCCTCAGCCAGCACAGCCACAGCCAGCTGAGCCACCGTCACAGTCACAGCGCGGTGAGTGGTGGTTGCAAGGAGGGAGGCGAAGGGAGCGGCACGAGTGGCGGAACGCGCTCCCTGCTGTCGTCCGGTTCGTCGCACGCGTCCACCAGCATGGAGCGGGCACCCTCGACCGAGAGCTTGAACATCCGCACGGACGAAAAGATGCCGGCGAAGGGGGAAATCTCCGAGCAGGAAAGCAACGGCGACATGGACATGACGTCGTGGAACCATCGGATGTACGCCGTGGTCGAGAATATGCCCATCTATCCGAGCTCGTACGATTTATCGACCGCACAGGAGTGCTGGAATCTGAGCAGCCGCAATCAGGGCATCTTTGCCGTGACGGACCATTtctaccaccagcagcaacagcaacagcagcagcagcaacaacacaacagtGGTAGTAATAATAACTCACACGGCACCACGGTCAACGGCCAGTACATGACGTCACGCGTAGCTTTCCAATTTTCCTCAACCGGTCATCAacacctgcagcagcagcagcagcagcaccagcagcacggtTCGGCCGATGCGCCCTTGGATGGCGGTATGATGCAGGCGAGCAAGATCGAACCGCCGATGGATGTGGACAGCGATAGCGGGGAGGTGATGCCGAAGCTGCCGTTTGCGGACATGATGGTAGCGCGCATGCACGAGCCACCGGGTGCATACGATGAGGGCAgcagccaccatcaccatcaccagcagcagcagcagcaacaaacgctGCACCAGCCGTGTGAAACCAAGTACGAGGAAACGGTCGGTACGACGTCCTACTTTGGTGTTGCGACCTGCTCCGCCGTACCGGTGATGCAGCAGCCGACGGATGATCCCGTGCGGCCCAACCGACCGAAACCGTCCGGCAGCGGTGTCGCGCGCACCTACCGCTGTACGCTCTGCGCCAAGGTGTTCAGCTCGATCAAGCAACGGCGGCTGCACCAGCAGTGCGAGCACGTGGACGATCTGGTGGCACTGTCCTCGTCGCACCAGCAGGAGATGCGCGGCGAGGAGGACAATAAGCCGTTGTTGGATGGcagacagcaacaacagttgccccagcagcagcaccagcagcagcagcagcaacaggcacagcaacagcagcaactgtACAAGAAGGCGCCGATTCCCGTGGTCATGAACTATCACTGGATGAAGCAGGAGATCGAGCGAAAGAGTGAGGCGGCGCTGCGAAGCAGCCGGCTGCTGATGGCGGGCAGTAGCGCTGGCAGCAGCACGACTGTCGTCCTGCCGGGAACGAGCAGCGGGGAGGCAGCAccgggccagcagcagcagctagtgCTAGAGCAGCACGTGCAGGTGCAGTTGCAGACCGACGGCGGAACCGTTGCGGCGTTGAGCGCGTCCGCTGAGAGCGCGCTGCTGCCGGCGGCGCACTGCTCGGTGGCGGCACGCAACCGTTCTTACGTGTGCAGCACCTGCAGCCGGGAGTTCGACCGGTTCAACCTGTTCAACGAGCATCTGCTGGAGCATCCGGTGGAGTGTTCCGCGTGCGGGCGGCACTTCAAGCAGTGGCGCAACTTTTCGCTCCACATCAAGCGGCACCTCGGCATCAAGGAGCACCAGTGCCGGATGTGCGGCAAGCGGTTCGTCATCAAGCAGAAGCTGATCGAGCACATGCGGGTGCACACGGGGCACGCGCCGATCAAGTGCAAGCTGTGCAACCGGACGTTCAAGCGGTTCTCCAACCTGGCCCAGCACCGGAAGCGCTACCATCTGAACCGCACCGTCGTGAAGGAGGAGTACGTGTGCCAGCTGTGCGGCGAGGTGTTCCACACGATGGCCAAGATGGAGTGGCACAAGGAGACGCACGAGAAGAAGCCAAAATCGTGCCCGTACTGTCGGGAGAAGTtcatacaccgcaacagctTGACGCGCCACATCCGGCTGTCGCACACGGACAAGTACGCGAAGCTCGAGAACAAAACCGAACCGTGCAGCATCTGCCAGCAGCCGTACACGAAGACGAGCATGCGGCGCCACCTGGAGACGCACACCAAGGAGCGGATGGCGTATGCGTGCGGCATCTGCAACAAGCGGTTCACCACCAACTGGAACCTGAAGCAGCACAAGTGGACGCACACGAACCCGACGATGAAACCGTTCCAGTGCACGTACTGCCCGAGCGCGTTCGTGCGCGAGTCGGACTTTGTCACGCACGTCAATGCGCACCGGTCGATCCGGCCGTACACGTGCAATCACTGTGGCAGCCAGTTCATCCGGAAGTACAACTGGATCCGGCACACGCGCGAGCACGAGATCGACAAGGGGCACCGGTGCGACGTGTGCGGCCGCCAGTTCCACCGGAAGTACTACCTGACCGAGCACAAGCGCATCCACACGGGCGAGCGGCCGTTCGCGTGCAACATCTGCGGCAAGACGTCCGCGACCAAGACGAACCACAACAAGCACGTGCGGATACATCACGCGCGCGACCCACTCACGGCGGAAGGGTAA
Protein Sequence: MAIECPVCTLYLRSGMTLAEHLDTHPKENVIKALVSMVKPDSLPPFGSGPVEEPGTASEPVPAEGGSTAALHGQPGPSTSSTGASSSNAISFRPNERTSASVGIFEAQPSLFLDSALIATSATSSSSSTSSSSSSSSSTTTPATVQVNLTSSQAPQVTVVKKIDVHGVPCFQVNNVTLVKRELVQPVAAAAPPPPPPPPPALPAPSVATVGTVPNELAAIGPLGDEFTEPSGSGSSSRVVYPRYTNELYSGPPPPYSRAISSTVASSTQITPVQQQQQQQTLQLSITKSSVGGLGVVGQQIQLLAKNLSEASVSAFKQYPASAVQTVSVLDRGSHEEPAVATASVASPSAPVGTPKLLYSVATTAGPRTAGTAITSTTTTTTTTANTPSASTALVDHLATGVPTITTTTTTGGTKTTVSTPPSSSKSNVVKVLSNVKVHTDLKDFQDIIMHLNAGQMSIVGDKTSLIPPVTERRPSAFAASTPGRSLLAITPAKSELPVEQQQQQQQSLCNAGMPTTKSEIEDLTGDYDHEVEYSGSWQEMDDHYADGEVRGQQWEGEEEEGAGGSGKRFRSASEQRETLPAAAASLDERMAPGEMMATGGGGAACSSGSAMVTSVIRKTPQPVPCALSPPAPQQESKANVKRLVFRVAGNSATPTTVTISPAGPSSAPKIVRAWQGIKVEEDGTEPASSNAGGIGGVVEPERAANDASAINAAAAAAPPPIATASTSLDYGAIKQKRGGFRPPKKLAIKPKRSSVGEGPAPSTSGKQGAPMQVDETEPAQPPAPTTMVMATALTTLADVVCTTAAAGQHLTAEPFCSSSSFNGITAVIQKTEATAHPSPYATEQQQQQQQQPNSSAGDGIADAYHHHPHHQPPDPVIKQEYSQPHAMPAPSASAAAGTLASSSSVYGVRSSYGLVPTSTGTASAPSSSTPAAVRLMPQHRPSTEIDVGAYNISYVGEAGETIYHPLPKRDGKAFGAQELLPVGGNGLAVGGESVADGSTAAPAHPDSRRMEVEEVEEDEEEELGEEQMELEEDDEDAPELEEEDEEEEEDEEEEDEDDEDDEEEEEKELEEDLIDEEEKEAHVHGELGQEEEEEEEVQLGSDEEEEEDDDEEEEEEEEDEEEEEEDEYDDDDVYEVEPRPVAGRYERVDASSQPEPHGRRRLLMVVSKPATATVTAAEAAESNGPYERPLPVDPVAEVVASGSLVVKRLPAPVPGTPDDEKDLLEAGPSTRMLERSGIPRPKFRITNADPFRPAAGLEPVRKTEVDAEPEYECSDSKDFLEQSLGSNPAVGGTTVAAHEQIQTTGGPLVALKAAKAEPCHDGQDDGQDTSASSFLDLSTVRKGGLPPGPVTTDTSSSNSSSNSSNSSSSHSTTNISLSQHSHSQLSHRHSHSAVSGGCKEGGEGSGTSGGTRSLLSSGSSHASTSMERAPSTESLNIRTDEKMPAKGEISEQESNGDMDMTSWNHRMYAVVENMPIYPSSYDLSTAQECWNLSSRNQGIFAVTDHFYHQQQQQQQQQQQHNSGSNNNSHGTTVNGQYMTSRVAFQFSSTGHQHLQQQQQQHQQHGSADAPLDGGMMQASKIEPPMDVDSDSGEVMPKLPFADMMVARMHEPPGAYDEGSSHHHHHQQQQQQQTLHQPCETKYEETVGTTSYFGVATCSAVPVMQQPTDDPVRPNRPKPSGSGVARTYRCTLCAKVFSSIKQRRLHQQCEHVDDLVALSSSHQQEMRGEEDNKPLLDGRQQQQLPQQQHQQQQQQQAQQQQQLYKKAPIPVVMNYHWMKQEIERKSEAALRSSRLLMAGSSAGSSTTVVLPGTSSGEAAPGQQQQLVLEQHVQVQLQTDGGTVAALSASAESALLPAAHCSVAARNRSYVCSTCSREFDRFNLFNEHLLEHPVECSACGRHFKQWRNFSLHIKRHLGIKEHQCRMCGKRFVIKQKLIEHMRVHTGHAPIKCKLCNRTFKRFSNLAQHRKRYHLNRTVVKEEYVCQLCGEVFHTMAKMEWHKETHEKKPKSCPYCREKFIHRNSLTRHIRLSHTDKYAKLENKTEPCSICQQPYTKTSMRRHLETHTKERMAYACGICNKRFTTNWNLKQHKWTHTNPTMKPFQCTYCPSAFVRESDFVTHVNAHRSIRPYTCNHCGSQFIRKYNWIRHTREHEIDKGHRCDVCGRQFHRKYYLTEHKRIHTGERPFACNICGKTSATKTNHNKHVRIHHARDPLTAEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00102535;
90% Identity: iTF_00102535;
80% Identity: -