Basic Information

Insect: Anopheles gambiae
Gene Symbol: wdn
Assembly: GCF_000005575.2
Location: NT:6146692-6148924[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0011 0.054 13.5 1.5 2 22 105 125 104 125 0.96

2 10 0.006 0.3 11.1 0.9 1 23 133 155 133 155 0.95

3 10 2e-07 1e-05 25.2 3.3 1 23 161 183 161 183 0.98

4 10 0.00074 0.038 14.0 0.1 2 23 212 234 211 234 0.96

5 10 0.059 3 8.0 0.1 2 23 242 262 241 262 0.93

6 10 1.2e-06 6e-05 22.8 3.8 1 23 268 290 268 290 0.98

7 10 8.9e-06 0.00045 20.0 4.4 1 23 296 318 296 318 0.98

8 10 0.00038 0.02 14.9 4.3 1 23 324 346 324 346 0.96

9 10 0.00043 0.022 14.7 1.0 1 23 352 374 352 374 0.97

10 10 6.1e-05 0.0031 17.4 3.0 1 23 380 403 380 403 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0011	0.054	13.5	1.5	2	22	105	125	104	125	0.96
2	10	0.006	0.3	11.1	0.9	1	23	133	155	133	155	0.95
3	10	2e-07	1e-05	25.2	3.3	1	23	161	183	161	183	0.98
4	10	0.00074	0.038	14.0	0.1	2	23	212	234	211	234	0.96
5	10	0.059	3	8.0	0.1	2	23	242	262	241	262	0.93
6	10	1.2e-06	6e-05	22.8	3.8	1	23	268	290	268	290	0.98
7	10	8.9e-06	0.00045	20.0	4.4	1	23	296	318	296	318	0.98
8	10	0.00038	0.02	14.9	4.3	1	23	324	346	324	346	0.96
9	10	0.00043	0.022	14.7	1.0	1	23	352	374	352	374	0.97
10	10	6.1e-05	0.0031	17.4	3.0	1	23	380	403	380	403	0.98

Sequence Information

Coding Sequence: ATGGAAGATGCGGTTACGGTGAAGTGCCCGCCGGAAATATCGCACGAAGAACGGAAAGAGTCGCCCCCGCGAGGACCTAAAACGGCAACACAGGATGAGAAAGTGAAGAAAAGCGTTGTCAATGGTAGCAGCAAGCAAAAGGAACTCGTTGGTGgcaATGACTTGAAGCTGGTGATGGAACCACAAAACCCTTCCCCCACCAAGTATTTCGACACGAACGGCGTACCGCTGCGCAAGGCGGTAGAGGAAGGAAACCTGGGGCAAACGGCGGACCGGGAAGGGCTCGATAAGAAGCCGAGCAAAGTGACCATCAAATGCTGTAACTGTGAGAAAACGTTTACCTCTCGTGCGGCGTATGAGCTGCACTATCGCACCAACTATCAACAGGAACCAGTTTACGAGTGTCCGGTGTGCGACAAGCGCATCAAACAGTACCGGGCGTACCAGCTGCATAGCTACCGGCACAGCGCCAACCAGCGCTTTACCTGTCCCGAATGCTCCAAAACGTTCCACCAAAAGTCTGATCTCACGCGCCACCAAAACATCCACCAGCCCCCTGGCAGCAACGGTTCCGGCACGTCCAAGGAACGCGGTGCGGCGAAGAATGGTGGCGATGGAAACGAGCAAGTCATACCCTGCCCCCGCTGTGATGCCACCTTTGGTACGCAGGCCGAATTCAAGGAACATTCCCGAAAGCTTCATCGCACACCAAAGCAGCTGGTCGAGTGTCCGGACTGTGGAAAATTGCTTTCCACCGGTAGCCTTTACTCGCACCGTAAAATACACTCCGAAAGCCCAAAGTTCTCGTGCCCCGAGTGTGACCGCACATTCGTGCAGAAGATCAACCTCATTCATCACCACAAAACGCACCTCACCGAGCGGCCCTTCCAGTGCGGCCAGTGTGATAAAGCGTTCTGCGAAAAGGCACACCTGCAGCGGCACCTCAACTACCACTCCCAGGAGCGGCCCTACCGCTGTGAGCTGTGCGGCAAGTGCTACAAAACGGAGCGCTGCCTCAAGGTACACTCCGCCGTCCACAACAACGAGCGGCCGTTCGTGTGCACCGAGTGCAACAAAGGCTTTCTCAGCAGCTCCAAGCTGCGGCAGCACAGCAACATCCACTCGGGGCTGCGGCCGTTCAAGTGCAAATATTGTACGCGCGATTTCACCAACTTCCCGAACTGGCTGAAGCACATCCGTCGCCGGCACAAGGTGGACCACCGGACCGGCGAAAAGCTGGACAGTGTGCCGAAGTTTATGACGAAGAAAAAGCTACCCGTCGATCGGGGGGTGCGCAAGAAGGAGCAACCGCCGGTCCCGCCCGAAGCGAGCGTAACCGCCGGTGGTGCGGgcgaaaaggggaaaaagcgAGCAGCGGTTAAGCAACGGCCCATCATACCGCTGCCCGACGTGCTGAAGGACGAATCGTTGCCGTACTTTAGCGAAAGTTCCAACATTGATCTCAATCTAGTTTGTAAGGAAGATCTGCTGCAGCCGCTGGCAGATGAGATGGAGGACATCTTTCAGTGCTTACCGTCCGACGAATCGAAGCTTAGcattccggagccgttggagcagCTCAGCGGCGGCACCAATGCCGTCGACGTACCGCTCAACGGTGGTAGTCTGCTTCAACCGGAAGTGGATTGTGATTTTAGTGTAAGAAGCCCGATGGCGGACCAGTCCAGCGTTTGCAACGATCTCATCACGCAAGAACTCCCCAGCAATGCATTGTCGAGCTGCGAGGAAGAAACGTTCAGTGGTACGCTACTGTACGATGCACATCTACCCATTCTGCCCGCTATGGTATCGttctgcagcaacagcagcgagGAGCAACAGTTTCGGCTCATCAATCCACACTTTATACACCTGACCAATCCCGCACCGTTTCTCGCCGGAAGCTCCAAGTTGCCATCGGACAGTGGTACCGTTCCGGTTTCGATTGGCGAATGA
Protein Sequence: MEDAVTVKCPPEISHEERKESPPRGPKTATQDEKVKKSVVNGSSKQKELVGGNDLKLVMEPQNPSPTKYFDTNGVPLRKAVEEGNLGQTADREGLDKKPSKVTIKCCNCEKTFTSRAAYELHYRTNYQQEPVYECPVCDKRIKQYRAYQLHSYRHSANQRFTCPECSKTFHQKSDLTRHQNIHQPPGSNGSGTSKERGAAKNGGDGNEQVIPCPRCDATFGTQAEFKEHSRKLHRTPKQLVECPDCGKLLSTGSLYSHRKIHSESPKFSCPECDRTFVQKINLIHHHKTHLTERPFQCGQCDKAFCEKAHLQRHLNYHSQERPYRCELCGKCYKTERCLKVHSAVHNNERPFVCTECNKGFLSSSKLRQHSNIHSGLRPFKCKYCTRDFTNFPNWLKHIRRRHKVDHRTGEKLDSVPKFMTKKKLPVDRGVRKKEQPPVPPEASVTAGGAGEKGKKRAAVKQRPIIPLPDVLKDESLPYFSESSNIDLNLVCKEDLLQPLADEMEDIFQCLPSDESKLSIPEPLEQLSGGTNAVDVPLNGGSLLQPEVDCDFSVRSPMADQSSVCNDLITQELPSNALSSCEEETFSGTLLYDAHLPILPAMVSFCSNSSEEQQFRLINPHFIHLTNPAPFLAGSSKLPSDSGTVPVSIGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104571;
90% Identity: iTF_00104571; iTF_00107160; iTF_00093631; iTF_00101129;
80% Identity: -