Basic Information

Insect: Anopheles arabiensis
Gene Symbol: wdn
Assembly: GCA_016920715.1
Location: NC:6034686-6037702[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0011 0.054 13.5 1.5 2 22 113 133 112 133 0.96

2 10 0.0063 0.3 11.1 0.9 1 23 141 163 141 163 0.95

3 10 2.1e-07 1e-05 25.2 3.3 1 23 169 191 169 191 0.98

4 10 0.00025 0.012 15.5 0.1 2 23 221 243 220 243 0.96

5 10 0.063 3 8.0 0.1 2 23 251 271 250 271 0.93

6 10 1.2e-06 5.9e-05 22.8 3.8 1 23 277 299 277 299 0.98

7 10 9.4e-06 0.00045 20.0 4.4 1 23 305 327 305 327 0.98

8 10 0.00041 0.019 14.8 4.3 1 23 333 355 333 355 0.96

9 10 0.00046 0.022 14.7 1.0 1 23 361 383 361 383 0.97

10 10 6.5e-05 0.0031 17.4 3.0 1 23 389 412 389 412 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0011	0.054	13.5	1.5	2	22	113	133	112	133	0.96
2	10	0.0063	0.3	11.1	0.9	1	23	141	163	141	163	0.95
3	10	2.1e-07	1e-05	25.2	3.3	1	23	169	191	169	191	0.98
4	10	0.00025	0.012	15.5	0.1	2	23	221	243	220	243	0.96
5	10	0.063	3	8.0	0.1	2	23	251	271	250	271	0.93
6	10	1.2e-06	5.9e-05	22.8	3.8	1	23	277	299	277	299	0.98
7	10	9.4e-06	0.00045	20.0	4.4	1	23	305	327	305	327	0.98
8	10	0.00041	0.019	14.8	4.3	1	23	333	355	333	355	0.96
9	10	0.00046	0.022	14.7	1.0	1	23	361	383	361	383	0.97
10	10	6.5e-05	0.0031	17.4	3.0	1	23	389	412	389	412	0.98

Sequence Information

Coding Sequence: ATGCACCTTTTGGGCAAACACACCATGGAAGATGCGGTTACGGTGAAGTGCCCGCCGGAAATATCGCACGAAGAACGGAAAGAGTCGCCCCCGCGAGGACCTAAAACGGCAACACAGGATGAGAAAGTGAAGAAAAGCGTTGTCAATGGTAGCAGCAAGCAAAAGGAACTCGTTGGTGGCAATGACTTGAAGCTGGTGATGGAACCGCAAAACCCTTCCCCCACCAAGTATTTCGACACGAACGGTGTACCGCTGCGCAAGGCGGTAGAGGAAGGGAACTTCGAGCAAACGGCGGACAGGGAAGGGCTCGATAAGAAGCCGAGCAAAGTGACCATCAAATGCTGTAACTGTGAGAAAACGTTTACCTCCCGTGCGGCGTATGAGCTGCACTATCGCACCAACTATCAACAGGAACCGGTTTACGAGTGTCCGGTGTGCGACAAGCGCATCAAACAGTACCGGGCGTACCAGCTGCATAGCTACCGGCACAGCGCCAACCAGCGCTTTACCTGTCCCGAGTGCTCCAAAACGTTCCACCAAAAGTCTGATCTCACGCGCCACCAAAACATCCACCAGCCCCCTGGCAGCAACGGTTCCGGCACGTCCAAGGAGCGCAGTGCGGCGAAGAATGGTGGGGAGAATGGGAACGAGCAAGTCATACCCTGCCCCCGCTGTGATGCCACCTTTGCTACGCAGGCCGAATTCAAGGAACATTCCCGAAAGCTTCATCGCACACCAAAGCAGCTGGTCGAGTGTCCGGACTGTGGAAAATTGCTTTCCACCGGTAGCCTTTACTCGCATCGTAAAATACACTCCGAAAGCCCAAAGTTCTCGTGCCCCGAGTGTGACCGCACGTTCGTGCAGAAGATCAACCTCATTCATCACCACAAAACGCACCTCACGGAGCGGCCCTTCCAGTGCGGCCAGTGTGATAAAGCGTTCTGCGAAAAGGCACACCTGCAGCGGCACCTCAACTACCACTCCCAGGAGCGGCCCTACCGCTGTGAGCTGTGCGGCAAGTGCTACAAAACGGAGCGCTGCCTCAAGGTACACTCCGCCGTCCACAACAACGAGCGGCCGTTCGTGTGCACCGAGTGCAACAAAGGCTTTCTCAGCAGCTCCAAGCTGCGGCAGCACAGCAACATCCACTCGGGGCTGCGGCCGTTCAAGTGCAAATATTGTACGCGCGATTTCACCAACTTCCCGAACTGGCTGAAGCACATCCGTCGCCGGCACAAAGTGGACCACCGGACCGGCGAAAAGCTGGACAGTGTGCCGAAGTTTATGACGAAGAAAAAGCTACCCGTCGATCGGGTGGTGCGCAAGAAGGAGCAACCGCCGGCCCTGCCCGAAGCGAGCGTAACCGCCGGTGGTGCGggcgaaaaggggaaaaagcgAGCGGCGGTTAAGCAACGGCCCATCATACCGTTGCCCGACGTGCTGAAGGACGAATCGTTGCCGTACTTTAGCGAAAGTTCCAACATTGATCTCAATCTAGTTTGTAAGGAAGATCTGCTGCAGCCGCTGGCAGATGAGATGGAGGACATCTTTCAGTGCTTACCGTCCGACGAATCGAAGCTTAGcattccggagccgttggagcagCTTGGCGGCGGCACCAATGCCGTCGACGTACCGCTCAACGGTGGTAGTCTGCTTCAACCGGAAGTGGATTGTGATTTTAGTGTAAGAAGCCCGATGGCGGACCAGTCCAGCGTTTGCAACGATCTCATCACGCAAGAACTCCCCAGCAATGCATTGTCGAGCTGCGAGGAAGAAACGTTCAGTGGTACGCTACTGTACGATGCACATCTACCCATTCTGCCCGCTATGGTATCGttctgcagcaacagcagcgagGAGCAACAGTTTCGGCTTATCAATCCACACTTTATACACCTGACCAATCCCGCACCGTTTCTCGCCGGAAGCTCCAAGTTGCCATCGGACAGTGGTACCGTTCCGGTTTCGATTGGCGAATGA
Protein Sequence: MHLLGKHTMEDAVTVKCPPEISHEERKESPPRGPKTATQDEKVKKSVVNGSSKQKELVGGNDLKLVMEPQNPSPTKYFDTNGVPLRKAVEEGNFEQTADREGLDKKPSKVTIKCCNCEKTFTSRAAYELHYRTNYQQEPVYECPVCDKRIKQYRAYQLHSYRHSANQRFTCPECSKTFHQKSDLTRHQNIHQPPGSNGSGTSKERSAAKNGGENGNEQVIPCPRCDATFATQAEFKEHSRKLHRTPKQLVECPDCGKLLSTGSLYSHRKIHSESPKFSCPECDRTFVQKINLIHHHKTHLTERPFQCGQCDKAFCEKAHLQRHLNYHSQERPYRCELCGKCYKTERCLKVHSAVHNNERPFVCTECNKGFLSSSKLRQHSNIHSGLRPFKCKYCTRDFTNFPNWLKHIRRRHKVDHRTGEKLDSVPKFMTKKKLPVDRVVRKKEQPPALPEASVTAGGAGEKGKKRAAVKQRPIIPLPDVLKDESLPYFSESSNIDLNLVCKEDLLQPLADEMEDIFQCLPSDESKLSIPEPLEQLGGGTNAVDVPLNGGSLLQPEVDCDFSVRSPMADQSSVCNDLITQELPSNALSSCEEETFSGTLLYDAHLPILPAMVSFCSNSSEEQQFRLINPHFIHLTNPAPFLAGSSKLPSDSGTVPVSIGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00104571;
90% Identity: iTF_00102532;
80% Identity: -