Basic Information

Insect: Anopheles gambiae
Gene Symbol: FTZ-F1
Assembly: GCF_000005575.2
Location: NT:18364960-18482962[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 1 1.2e+04 -5.8 6.7 132 163 37 66 3 85 0.62

2 4 1 1.2e+04 -8.4 22.9 41 159 95 211 68 263 0.48

3 4 0.034 4.2e+02 -0.4 4.5 65 155 313 400 293 435 0.47

4 4 6.7e-91 8.4e-87 291.7 9.3 1 408 658 1098 658 1099 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	1	1.2e+04	-5.8	6.7	132	163	37	66	3	85	0.62
2	4	1	1.2e+04	-8.4	22.9	41	159	95	211	68	263	0.48
3	4	0.034	4.2e+02	-0.4	4.5	65	155	313	400	293	435	0.47
4	4	6.7e-91	8.4e-87	291.7	9.3	1	408	658	1098	658	1099	0.79

Sequence Information

Coding Sequence: ATGCACGAGGAAGCCACCTCAACGGCTAGCTCGTCCACGACCTCCCCGCCCGAAACGTCCTCGTCCTCGAACATTGTGTACCCGAACGGTGACCCCATGCTGCTGTCCACCTCGCCCACACCCGGCCCGGGTGTGgcttcctcctcgtcctcctccgcctcctcctcctcctctacGTCGTCATCCACTACCGGCACCGCTAACCTGTACGAGGCGGTAGACCAGCAGGAGCTGCTACTCTCCAACAGTCATCACAGTGCGGCCTTCCACGGCCATCAGCATCaaattcagcagcagcagcaaatgcaccaccagcaacattCCCAGCAAGCGTTACAGCACGTAACGCCCAACCTGACAGCAGTGGGTACCAAAATTATCGTTACCGGAGGTGTGCATCAtaccatgcagcagcagcagcatcatcttTCGCACGAACATCAGAcgcatcatcaacatcaaacgCAACATCACAGCCATCACAaccacctgcagcagcagcaccaccaccaccatccgttACACCACGTACAgacgcagcagcaccatcagccaAGTTCCTCCACGAACGTGATCGTTCCGGGCACGAGCCACGGCTCGCCACCTCTGCTCGTTCAGGCCAGCTCGAGCGGCGTCTCCGACATGCTGCTCGGGCAGGATCCGATAACGACGACCAccgtggcggcggcggcagcgaccGGCGCCACCACCCTGCTCGCGCTGTCCCCGGACGACGTGGTGGAATCGGTCATCGATGGGCGGGTCGTAACGGCCACGGAGGAGGACACACTGCTCAGCAGTCTGGCCggcacgacgacgaccgacggtggtggtggtgtggtggtggacgAGGTCGATGATCACGTCGTCTCGATGGTCGGTGCCGATGGGACGCTGCTGGGGTGCGGTGACCCACTGCAAGGGGTCACACACCACtctcaccaccatcagcagcaccatcttcatcagcagcagcagcagcccagcTCTTCGTCCAGTATTACGATCGTCACGGAAGAGTCCATCCTTCCGCTGGCGGTGACGTCGGCAGCATCGTCGTGCGTCCTGGCGGCCGTTACTACCCGCCGTTCGCCCGCCTCGTCCACGTCCGGTTCGTCCACACCGGCCGCATCGTCCTCCGGTGCGGTGCCGATGTCCTCGGGCGGCACGATCGGCAGCAGCCCCTCGTCGTCCACCAGCGCCACGACGGCCGTTGCGGTTGCGACCGTCGGGAGCAGTGGTGGGACGCACGCTGGGGCCGCTTGCGGGTCGTCGTCGGCGTCGGCGGCTGGCATCGTTATGTCCGCCCTGTCGGTTCAtaacgatgctgctgccgcccaCCTGACCGAGGCGATCGAGATCAACATCCCGGAGGAGGACGACGGTTGCAGCTACGGCGAGGATTCGGACGgcggcggtggcggtgttgGCGGGACCACCGGTGGCGGTCCGTACCATCACGGTGGCAGTGATGGGGGCATCggcggcaacagcaacagtagcagcggcggcggcggcggcggaggcaGCCAAGCGGCCGGCGGCCAAAcggcgggcggcggcggctcctcctcggcagcggcggcagcagcggcagcctATCTGGCGATACCGGCCTCAGGTACTAGCGGTGGTAGTTGTAGTAGTGGCGGGGGCGCGTCCGGCGGCAGCCTCATTGAGCACCAAACCGCACTCAATAGTCTGAGCGTCGTGTCCGCCATCCAATGCGATCAAActgatttgaaatatttcattgaaGAGCTGTGCCCGGTGTGCGGCGACAAGGTGTCCGGCTACCACTACGGGCTGCTAACGTGCGAATCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAACAAGAAGGTCTACACGTGCGTCGCCGAGCGCCAGTGCCACATCGACAAGACGCAGCGGAAGCGCTGCCCGTACTGCCGCTTCCAGAAGTGTCTCGAGGTCGGCATGAAGCTGGAAGCCGTGCGAGCCGACAGGATGCGCGGCGGACGAAACAAGTTCGGGCCCATGTACAAGCGAGACCGGGCGCGGAAGCTGCAGATCATGCGCCAGCGGCAGCTCGCCCTCCAGGCGCTGCGTGGCTCGATCGGCGGAGGCGTCGGCATCGGTACGCTCGGTTCGGACGGCGTTTCGCCCCAATTGCAGGGTCTCGATTACCACCAGCCGTACTCGAGCATGCACATCAAGCAGGAAATCCAGATACCGCAGGTCTCATCGCTCACGTCATCGCCGGATAGCTCGCCGAGCCCGATCGCGATCGCACTCGGCCAGGTTAATCCGCAGACGACGATATCGCTCAGCAGCACCGGAGTCGGCggcaacggtggtggtggcggtggtggcggcggcggcggcggtggcggcaacGGTGGTGGCAGCAATGGGTCCGGTGCCGGCACCGGCAGCTCCAACTCGAACAGCGCCACCAACATCCAGAATCCACTGTCCGACTCGAAGCTGTGGATGAGCGCCAACTCGACGACCGCCTCGCCCCACTCGCTCAGCCCGAAGGCGTTCAGCTTCGACTCGAATCCCACCAGCACGGCCGACTCCGGCAACCCGGCCGACACCCTAAGGCTAGTGGTATCGCCGATGATCCGCGAGTTCGTCCAGTCGATCGACGATCGCGAATGGCAGACGTCGCTGTTCTCGCTGCTCCAGAGCCAGTCCTACAATCAGTGCGAGGTCGACCTGTTCGAGCTGATGTGCAAAGTATTAGACCAAAATCTGTTCTCCCAGGTCGATTGGGCGCGAAATACGATATTCTTCAAGGATTTGAAGGTTGACGATCAGATGAAGCTCCTCCAGAACAGCTGGTCGGATATGCTGGTGCTCGACCACATACACCAGCGCCTGCACAACGGGCTGCCGGACGAAACCACCCTGCACAACGGGCAGAAGTTTGATCTCTTAGGTTTAGGGCTGCTGGGCGTGCCGAGCCTGGCCGAGCACTTTAACGAGCTGCAGAACAAGCTGCAGGAGCTCAAGTTTGACGTCGGCGACTACATCTGCATGAagttcttgctgctgctgaatccCGATGTCCGGGGGATCACCAACCGAAAGACGGTCGTCGAGGGCTACGAGAACGTGCAAGCGGCCCTGCTGGACTACACGCTTACCTGCTATCCGTCGGTGCCTGACAAGTTCAGTAAGTTGCTCAGTATTATTCCGGAGATCCACGGAATGGCAGCACGGGGCGAGGAGCATCTGTACATCAAGCACTGTGCCGGCAGTGCACCCTCCCAAACGCTGCTGATGGAGATGCTGCATGCCAAGCGGAAATGA
Protein Sequence: MHEEATSTASSSTTSPPETSSSSNIVYPNGDPMLLSTSPTPGPGVASSSSSSASSSSSTSSSTTGTANLYEAVDQQELLLSNSHHSAAFHGHQHQIQQQQQMHHQQHSQQALQHVTPNLTAVGTKIIVTGGVHHTMQQQQHHLSHEHQTHHQHQTQHHSHHNHLQQQHHHHHPLHHVQTQQHHQPSSSTNVIVPGTSHGSPPLLVQASSSGVSDMLLGQDPITTTTVAAAAATGATTLLALSPDDVVESVIDGRVVTATEEDTLLSSLAGTTTTDGGGGVVVDEVDDHVVSMVGADGTLLGCGDPLQGVTHHSHHHQQHHLHQQQQQPSSSSSITIVTEESILPLAVTSAASSCVLAAVTTRRSPASSTSGSSTPAASSSGAVPMSSGGTIGSSPSSSTSATTAVAVATVGSSGGTHAGAACGSSSASAAGIVMSALSVHNDAAAAHLTEAIEINIPEEDDGCSYGEDSDGGGGGVGGTTGGGPYHHGGSDGGIGGNSNSSSGGGGGGGSQAAGGQTAGGGGSSSAAAAAAAAYLAIPASGTSGGSCSSGGGASGGSLIEHQTALNSLSVVSAIQCDQTDLKYFIEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERQCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQIMRQRQLALQALRGSIGGGVGIGTLGSDGVSPQLQGLDYHQPYSSMHIKQEIQIPQVSSLTSSPDSSPSPIAIALGQVNPQTTISLSSTGVGGNGGGGGGGGGGGGGGNGGGSNGSGAGTGSSNSNSATNIQNPLSDSKLWMSANSTTASPHSLSPKAFSFDSNPTSTADSGNPADTLRLVVSPMIREFVQSIDDREWQTSLFSLLQSQSYNQCEVDLFELMCKVLDQNLFSQVDWARNTIFFKDLKVDDQMKLLQNSWSDMLVLDHIHQRLHNGLPDETTLHNGQKFDLLGLGLLGVPSLAEHFNELQNKLQELKFDVGDYICMKFLLLLNPDVRGITNRKTVVEGYENVQAALLDYTLTCYPSVPDKFSKLLSIIPEIHGMAARGEEHLYIKHCAGSAPSQTLLMEMLHAKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00093486;
90% Identity: iTF_00093486;
80% Identity: -