Afun002563.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles funestus
Gene Symbol
-
Assembly
None
Location
Contig1:96312902-96316093[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00013 0.0076 16.4 1.6 1 23 234 256 234 256 0.98
2 15 0.002 0.12 12.6 4.7 1 23 265 287 265 287 0.96
3 15 1.6e-06 9.5e-05 22.4 0.2 1 23 296 318 296 318 0.98
4 15 2.6e-05 0.0016 18.6 4.4 1 23 324 346 324 346 0.98
5 15 0.015 0.9 9.9 0.1 2 23 354 375 353 375 0.97
6 15 8.3e-05 0.005 17.0 3.4 1 23 381 404 381 404 0.94
7 15 0.0025 0.15 12.3 6.1 1 21 410 430 410 431 0.94
8 15 0.24 15 6.1 4.6 3 23 439 460 437 460 0.94
9 15 7.2e-06 0.00044 20.3 0.6 1 23 509 531 509 531 0.97
10 15 4.4e-05 0.0027 17.8 0.4 1 23 542 564 542 564 0.97
11 15 0.00016 0.0096 16.1 6.4 1 23 594 616 594 616 0.99
12 15 0.61 37 4.8 4.2 2 23 651 672 650 672 0.94
13 15 0.0011 0.066 13.4 4.9 1 23 678 700 678 700 0.98
14 15 3.8e-07 2.3e-05 24.3 1.5 1 23 708 730 708 730 0.99
15 15 0.00045 0.027 14.7 0.7 1 23 736 759 736 759 0.96

Sequence Information

Coding Sequence
ATGGAATACAACAATAGCTACAACAAACCGTACTGTGGCGTCATTTCTCAGCCTATTCCGCCCTCCGGCAGCTCTGGTTTCTTCCCGGGAAATGATACGGCATCGACGTTCCTTAAAGTACCCAACCCACCGTACATCAAGCAGGAATCGGGTACAGTGGGCAGTGAGACGATGATCGTTGGTGGTACCGTCACACCTCCCGTAAACTACAGCCAGAATCAGCACTACGCGGCCGAGTATGGTGAATCGGTTGATGTGGAGAAACCCCTATTCTATCGGAAACCGTTCGACATGCCTTACCTGTCGAATCCGTACATGCAACCTCATCCGCAGCAATTTGCCCAACATCCGCTTCCACACATTGTTTCACACCCTAACCACCATCATGTGACGCACGTGCAACACCAACAGCAACAACATCTTCCACCACCTGCTCCGACAGTGTCATCCGATATGCATTCGCCACAGCTAATTGTAACAGAGCATGTGCAACGACAGCAACATCCAACAAACTTCCACGAGTATTTTGATCAATCGGATCCTTCCTCAATGGAACCATATGCTTACGTTCTGCAAAAGCCCGCCGTATCGATGTTGAACACGGAAACGCCGTCGTCGATGCTTTCTACCTCGTTTTCCGCAGCCCCAGCCGAGGCACGATCACCGTACGATATTGGTGAAGCACCCGAACCGGCCTGCTTTAAATGTGAAAGCTGCCCGAAAACGTTCGACACAATGGTGAAGCTAGAAAAGCACAACAAAACACATCTGTCGAACGGTGGCCAACAGGATTTCAAATGCCGGATGTGTGAAAAAACCTTTCGCACCAGAAGTACACTGATCTGTCACGAAAAGGTGCACGGTGAGAACGGAGTGGATAACACCTTTTCGTGTGTGGAGTGCGGCAAAGTGTTTGCGACTGCCGAAAAGCTGCAAGTTCACCGCCGTTTACACACGGGAGAAAAGCCTTATCAGTGCAAGGTGTGCCTCAAGCACTTTAACCATCAATCCAACTTGATCGTACACTCGCGCATTCACGAGAAGGTAAAGAAAGCGCTCAAATGTGCTCGTTGCAGTAAGGTGCTGGATAATGAGGAGCGTTTGGCCATCCATATGCGGTTGCATACGGGTGAAAAGCCGTACAAATGTTCGTACTGTGATAAGCGTTTCAATCACAAAAGTACGGTCAGTACGCACGAAAAGGCGGCACACATAGCGGCCAACTCGTTCAAGTGCGAACGGTGCCATAAGACGTTCAATCAAAAGTGCCAGCTGCAGTACCATGAGAAGTTGCAGGAGGAGCATACGATCGCGTGCGCCCACTGTGAGAAGGTATTCTGTTACAAGGCCAGCCACAAGGAGCACATGTTTAAGGTACATTTTCCACGCCCGAAAAAGGAACTGAAGAAGGAACAGGCGAGTGATGACAGAACGGGTGGTGTTGAGGATAGTGGTGGTGGTGGTGGTGGTGGTGGCGGCGGGACAAGCTCAAGCACTGGGAATGGCAATCAGGGACGGAACAAGTTCAAATGCAACGTATGTGACCGTCGGTTTTATTACAAACGTGCACTGGAAGTGCATATGGGTGTGCATGACGCTTCGCTGGACGTAAACGTGCTGTACTTTTCGTGCAACTACTGTCCGGAAACGTTCACCGAGGAGGATTCGCTGCAGACACATGAAGCCAAACATGTTGCCGCCGGGACGACCGATTTCCTGCAGAATATGAGGGAACTGGAACAGTCGGAAAATCCTGCCAACGGGCAGGTCGATGGTGGTTTTCGGTGCCCGTTATGCTTTAAGCGTTTCGAGGATCAACACACATTGCGCGATCACCACAAAACGCACCTTTGCTCGTACCCTGACTGTACCAAGTGTGGACCAGCGCATAGCGATGAGTTCGATCTTACGCGCAGTACGTACGATGCTAGTGATGACACGCGTGAAACGGTATGCAACATTTGCCACCGTCAATTGCCAACTTTCGAGCAATTTCAGAACCACTTCCATTACCATACGTCCCGTGTACCGTTCTACTGCTATCACTGTCGGGAGGAGTTTACGGACAAGCGGGAACTGTACAACCACTCGAGGACGCATGCACCGCGTGAACCGGAATCGTATACGTGCGAGGTATGCGCGAAGGTGTTCTCGACCAAGGGCAATTTTAAGCGGCATTTAAAATCTCACGAAACGGTACGCGCATTCGCGTGCGATCGTTGTTCCAAGCAGTACGACTACAAGAGCGCACTAGAGGTGCATCTGAAGCGATCACACGGTATCGAACTGTAA
Protein Sequence
MEYNNSYNKPYCGVISQPIPPSGSSGFFPGNDTASTFLKVPNPPYIKQESGTVGSETMIVGGTVTPPVNYSQNQHYAAEYGESVDVEKPLFYRKPFDMPYLSNPYMQPHPQQFAQHPLPHIVSHPNHHHVTHVQHQQQQHLPPPAPTVSSDMHSPQLIVTEHVQRQQHPTNFHEYFDQSDPSSMEPYAYVLQKPAVSMLNTETPSSMLSTSFSAAPAEARSPYDIGEAPEPACFKCESCPKTFDTMVKLEKHNKTHLSNGGQQDFKCRMCEKTFRTRSTLICHEKVHGENGVDNTFSCVECGKVFATAEKLQVHRRLHTGEKPYQCKVCLKHFNHQSNLIVHSRIHEKVKKALKCARCSKVLDNEERLAIHMRLHTGEKPYKCSYCDKRFNHKSTVSTHEKAAHIAANSFKCERCHKTFNQKCQLQYHEKLQEEHTIACAHCEKVFCYKASHKEHMFKVHFPRPKKELKKEQASDDRTGGVEDSGGGGGGGGGGTSSSTGNGNQGRNKFKCNVCDRRFYYKRALEVHMGVHDASLDVNVLYFSCNYCPETFTEEDSLQTHEAKHVAAGTTDFLQNMRELEQSENPANGQVDGGFRCPLCFKRFEDQHTLRDHHKTHLCSYPDCTKCGPAHSDEFDLTRSTYDASDDTRETVCNICHRQLPTFEQFQNHFHYHTSRVPFYCYHCREEFTDKRELYNHSRTHAPREPESYTCEVCAKVFSTKGNFKRHLKSHETVRAFACDRCSKQYDYKSALEVHLKRSHGIEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00105287;
90% Identity
-
80% Identity
-