Afon012533.1
Basic Information
- Insect
- Anopheles fontenillei
- Gene Symbol
- -
- Assembly
- GCA_008817895.1
- Location
- VTWG01006627.1:1-2934[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.072 4.1 7.8 2.9 1 21 105 125 105 128 0.93 2 13 0.004 0.22 11.8 0.9 1 23 238 260 238 260 0.97 3 13 8.6e-05 0.0049 17.0 2.0 2 23 263 284 262 284 0.96 4 13 1.9e-05 0.0011 19.1 1.9 1 23 290 312 290 312 0.98 5 13 9.3e-06 0.00053 20.0 3.5 2 23 319 341 318 341 0.96 6 13 0.0015 0.084 13.1 0.5 1 23 351 373 351 373 0.98 7 13 3.8e-05 0.0021 18.1 2.8 2 23 379 401 378 401 0.96 8 13 0.0082 0.47 10.8 0.6 3 23 415 434 414 434 0.97 9 13 1.5e-05 0.00084 19.4 0.9 1 20 441 460 441 463 0.92 10 13 0.00024 0.014 15.6 0.2 1 23 471 493 471 493 0.97 11 13 2.3e-05 0.0013 18.8 3.1 1 23 499 521 499 521 0.98 12 13 0.00013 0.0072 16.5 5.8 1 23 527 549 527 549 0.98 13 13 0.00081 0.046 13.9 3.5 1 23 555 577 555 578 0.95
Sequence Information
- Coding Sequence
- CAATTTTCCTCAACCGGTCATCaacacctgcagcagcagcagcagcaccagcagcacggtTCGGCCGATGCGCCCTTGGATGGCGGTATGATGCAGGCGAGCAAGATCGAACCACCGATGGATGTGGACAGCGATAGCGGGGAGGTGATGCCGAAGCTGCCGTTTGCAGACATGATGTACGAGGAAACGGTCGGTACGACGTCCTACTTTGGTGTTGCGACCTGCTCCGCCGTACCGGTGATGCAGCAGCCGACGGACGATCCCGTGCGGCCCAACCGACCGAAACCGTCCGGCAGCGGTGTCGCGCGCACCTACCGCTGTACGCTCTGCGCCAAGGTGTTCAGCTCGATCAAGCAGCGGCGGCTGCACCAGCAGTGCGAGCACGTGGACGATCTGAAGGCGCCGATTCCCGTGGTGATGAACTATCACTGGATGAAGCAGGAGATAGAGCGAAAGAGTGAGGCGGCGCTGCGAAGCAGCCGGCTGCTGATGGCGGGCAGTAGCGCTGGCAGCAGCACGACTGTCGTCCTGCCCGGCACGAGCAGCGGGGAGGCAGCAccgggccagcagcagcagctagtgCTAGAGCAGCACGTGCAGGTGCAGGTGCAGTTGCAGACCGACGGCGGAACCGTTGCGGCGTTGGGCGCGTCCGCTGAGAGCGCGCTGCTGCCGGCGGCGCACTGCTCGGTAGCGGCACGCAACCGTTCGTACGTGTGCAGCACCTGCAGCCGGGAGTTCGACCGGTTCAACCTGTTCAACGAGCATCTGCTGGAGCATCCGGTGGAGTGTTCCGCGTGCGGGCGGCACTTCAAGCAGTGGCGCAACTTTTCGCTCCACATCAAGCGGCACCTCGGCATCAAGGAGCACCAGTGCCGGATGTGCGGCAAGCGGTTCGTCATCAAGCAGAAGCTGATCGAGCACATGCGGGTGCACACGGGGCACGCGCCGATCAAGTGCAAGCTGTGCAACCGGACGTTCAAGCGGTTCTCCAACCTGGCCCAGCACCGGAAGCGCTACCATCTGAACCGCACCGTCGTGAAGGAGGAGTACGTGTGCCAGCTGTGCGGCGAGGTGTTCCACACGATGGCCAAGATGGAGTGGCACAAGGAGACGCACGAGAAGAAGCCAAAATCGTGCCCGTACTGTCGGGAGAAGTTCATACACCGCAACAGCTTGACGCGCCACATCCGGCTGTCGCACACGGACAAGTACGCGAAGCTCGAGAACAAAACCGAACCGTGCAGCATCTGCCAGCAGCCGTACACGAAGACGAGCATGCGGCGCCACCTGGAGACGCACACCAAGGAGCGGATGGCGTACGCGTGCGGCATCTGCAACAAGCGGTTCACCACCAACTGGAACCTGAAGCAGCACAAGTGGACGCACACGAACCCGACGATGAAACCGTTCCAGTGCACGTACTGCCCGAGCGCGTTCGTGCGCGAGTCGGACTTTGTCACGCACGTCAATGCGCACCGGTCGATCCGGCCGTACACGTGCAACCACTGTGGCAGCCAGTTCATCCGGAAGTACAACTGGATCCGGCACACGCGCGAGCACGAGATCGACAAGGGGCACCGGTGCGACGTGTGCGGCCGCCAGTTCCACCGGAAGTACTACCTGACCGAGCACAAGCGCATCCACACGGGCGAGCGGCCGTTCGCGTGCAACATCTGCGGCAAGACGTCCGCGACCAAGACGAACCACAACAAGCACGTGCGGATACATCACGCGCGCGACCCACTCACGGCGGAAGGGTAA
- Protein Sequence
- QFSSTGHQHLQQQQQHQQHGSADAPLDGGMMQASKIEPPMDVDSDSGEVMPKLPFADMMYEETVGTTSYFGVATCSAVPVMQQPTDDPVRPNRPKPSGSGVARTYRCTLCAKVFSSIKQRRLHQQCEHVDDLKAPIPVVMNYHWMKQEIERKSEAALRSSRLLMAGSSAGSSTTVVLPGTSSGEAAPGQQQQLVLEQHVQVQVQLQTDGGTVAALGASAESALLPAAHCSVAARNRSYVCSTCSREFDRFNLFNEHLLEHPVECSACGRHFKQWRNFSLHIKRHLGIKEHQCRMCGKRFVIKQKLIEHMRVHTGHAPIKCKLCNRTFKRFSNLAQHRKRYHLNRTVVKEEYVCQLCGEVFHTMAKMEWHKETHEKKPKSCPYCREKFIHRNSLTRHIRLSHTDKYAKLENKTEPCSICQQPYTKTSMRRHLETHTKERMAYACGICNKRFTTNWNLKQHKWTHTNPTMKPFQCTYCPSAFVRESDFVTHVNAHRSIRPYTCNHCGSQFIRKYNWIRHTREHEIDKGHRCDVCGRQFHRKYYLTEHKRIHTGERPFACNICGKTSATKTNHNKHVRIHHARDPLTAEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00104551;
- 90% Identity
- -
- 80% Identity
- -