Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915040.1:8534208-8537697[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.0013 0.08 13.0 1.5 1 20 143 162 143 165 0.90

2 17 3.8e-05 0.0022 17.9 1.8 2 23 229 250 228 250 0.97

3 17 0.72 42 4.4 4.7 1 23 257 280 257 280 0.79

4 17 2.7e-05 0.0016 18.3 2.6 1 23 294 316 294 316 0.97

5 17 0.032 1.9 8.7 2.8 1 23 322 345 322 345 0.96

6 17 3.5 2.1e+02 2.3 0.2 1 23 469 492 469 492 0.90

7 17 3.5e-06 0.00021 21.1 1.0 1 23 520 542 520 542 0.93

8 17 1.3e-05 0.00077 19.3 1.7 1 23 548 571 548 571 0.98

9 17 0.076 4.5 7.5 2.7 1 23 580 603 580 603 0.97

10 17 0.00059 0.035 14.1 2.1 1 23 761 783 761 783 0.95

11 17 0.017 1 9.5 2.8 1 23 789 812 789 812 0.95

12 17 0.0085 0.5 10.5 0.9 1 23 823 846 823 846 0.97

13 17 5.6 3.3e+02 1.6 2.1 1 14 872 885 872 895 0.76

14 17 2.3 1.4e+02 2.8 5.1 2 23 912 933 911 933 0.95

15 17 3.5e-06 0.00021 21.1 2.3 1 23 958 980 958 980 0.98

16 17 0.00041 0.024 14.6 0.2 1 23 986 1009 986 1009 0.96

17 17 0.0014 0.084 12.9 0.9 2 23 1025 1047 1024 1047 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.0013	0.08	13.0	1.5	1	20	143	162	143	165	0.90
2	17	3.8e-05	0.0022	17.9	1.8	2	23	229	250	228	250	0.97
3	17	0.72	42	4.4	4.7	1	23	257	280	257	280	0.79
4	17	2.7e-05	0.0016	18.3	2.6	1	23	294	316	294	316	0.97
5	17	0.032	1.9	8.7	2.8	1	23	322	345	322	345	0.96
6	17	3.5	2.1e+02	2.3	0.2	1	23	469	492	469	492	0.90
7	17	3.5e-06	0.00021	21.1	1.0	1	23	520	542	520	542	0.93
8	17	1.3e-05	0.00077	19.3	1.7	1	23	548	571	548	571	0.98
9	17	0.076	4.5	7.5	2.7	1	23	580	603	580	603	0.97
10	17	0.00059	0.035	14.1	2.1	1	23	761	783	761	783	0.95
11	17	0.017	1	9.5	2.8	1	23	789	812	789	812	0.95
12	17	0.0085	0.5	10.5	0.9	1	23	823	846	823	846	0.97
13	17	5.6	3.3e+02	1.6	2.1	1	14	872	885	872	895	0.76
14	17	2.3	1.4e+02	2.8	5.1	2	23	912	933	911	933	0.95
15	17	3.5e-06	0.00021	21.1	2.3	1	23	958	980	958	980	0.98
16	17	0.00041	0.024	14.6	0.2	1	23	986	1009	986	1009	0.96
17	17	0.0014	0.084	12.9	0.9	2	23	1025	1047	1024	1047	0.94

Sequence Information

Coding Sequence: ATGATGAAGCCCGAGCAGGAACCCGAACCGGTCGTCGACGATGATCCGGTGGACGTCCCGAATCCGAACGCCGAATCGTACTGCCGGTTCTGTTTTTCGGAGAACGAGGTGGAACCACTCTTCTCGGCGGACGGCACCCAAGCGAGTGCGGAACTGCTGGAACGCATCTACGACTGCATCGGCATAAGACTGACGAAGAAAGAATACTGCCCCAGCGCCATTTGCTGGTCGTGTACGCTGACGATGGAAGAGTTCCAGTGCTTTCGCAAACGCTGCCTCAAGTTTGATGCGCTGGTGCGCCGCCTACGGCCGACGATAAAATCGGAACAGGGCTACGGCGGAACGACGGACCACCACAAATCGTTCGGCCGGCAGCAGGATAAAGCAGCTAAAAAAGTGGCTAACGCGTCATCCGAGGTGCGCTCGTTCCTGTGCCAGTATTGTCCCCGGACCTTCAAGCAGCGAATGTATCTGGATCAGCACATGTGGAAGCATCGGGATCGGGTCGCTGCCGAAGCGGCCACCAACCAAGCCATCAACAAGCGCTCGATGGCGGTGAACGGTAGCGGGAATGGTTCGATGGTGGTGATCAAAAAGGAACCGATCGTGGCGAGCAGTACTCCGACTCCTCCGCCACCACCGGTCGCCACCACCCAGACGGGCGCGCAAGTGGATCGCCCGATAAGCTGCGAGTACTGTCCGCGAAAGTTTACACGCCGCATGTACTACATGCAGCACCTGCGCAGACACAAACCGGAAGAGCGTCTGTTCCGGTGTCGCCACTGTACGCGCAGCTTCACTTCGCACATGAGACGCGTCGGCCACGAGCGTAAGATACACGGGTACTTAAGCAATCCCAAGATGGAGGAAAAGGATTCGTTCTCGTGTCCGAAGTGTGCGCGCGTGTTCAAGCATCGATCGTCGCTGCGGATGCATCTGCTCAACCACGACGGTCAGCTACCGTATGCGTGCGACATCTGCAACTGCCGCTTCTACAGTGTAAGCTATCTGGGGCTGCATAAAAAGCGTTACCACGGCCCGAACGCGGCCCGGTCGGTCGCCAACGGGACGTCCATTCCGTGTCTGTACTGTACGCGCTGGTTTTTGCGCGAGTGTGATCGATCGAGTCACATCAAGCAGATGCACGCGGACATGCACGCCAGCAAAGCATCGGCGGCCGGTTTCAACGAAATGCTCGCCGATTGCCCGCCGGCCGATAGCGAGGGCATGATCGACGATCCCGAGATGCTGCCACCGAACGTACACGAACCGATGATGGTCATCAAGGAGGAGGAACCGGATACGGCCGTTGTTGGCGCTGTCGGTGCCGCCGCCGCCGCTGGTGGTGGTGTCAATGATTCTACCGCCTCGTTAGCTTCACTCGCAAATCCGGGCGCATTCCAGTTCTACTGCTACTCCTGCGCCATGCCTTTCGACACCGAGGACATGTACTCGGAGCATCTGGACGATCAGCATCCGTTCGGGGGCGAGCAGTTGATGGATCAGCTGCAACCGTCCTCGTCGCCGGTCGAGCTGGACGAAAACGGTACGAAGGTGTTCCGCTGCCCGTACTGCCCGAAAACGTTCACGCGCAAATGGAGCATGACGCAGCACATTCCGACGCATCTCGGGCGGAAGGGCTACAAGTGTGAGTACTGCCCGGCCATCTTCACCCGCAACGAGTACCTGCGGACGCACCGGCAGCGGAAGCATCCGACGCTCCCGGAAACGGGCACGTACAAGTGTAGCTACTGTCCGCGGTTGTTCCACAAGGCGCGCTACAAGAAGGTGCACGAGCGGATCGCTCACATCAAGAAGGGGGACGTGCTGCCGGACGGGGACGATACGGAGGAGAGCGAACTCGTGGCCCTGACCGGGGCACCGTCCGGTGAGAAGCTGGACGAAAGTAGCTGCAGCATCGCGTTCGGCCCATCGTCCCGTGCGTCGGACAGTTTCGATCAAACGTCGAACGATGCGCACAGTGTGGCTGAGTCCGGGTGTGGGTCGGTTCAGCCCAACTACTCCGATCTGGAAGCCTCAGCACGGCTTGTGGTCGTGCTGGAGCGAATGCCACCGGAGCTGGTGGAACAGTATCGTTGGCAGATGGAGCTGTACGCGAACATGACGCCGGAAGAGCTGACGGCCCATTCGTCGGCGGATGAAACGTCCGCCGTGGATGATACGCTTGACGGAGATAAGCTCGAAATGCGGGACGATCTGGAACCGGCACCGACCGCACCGGTGTTCAAGCGAAAGCGCAGCAAATTCGGCATCACGCTGCACCCGTGTCCGCATTGCTCGAAGTTGTTTAAAACGCGTGGCGCACTGCGATTGCACGCTCTCTACCACAGCGGCGAGCTGCCGCACCGTTGCGACGAGTGTGGCGTGCAGTTCATGCGCTACAATCAGCTCGAGTATCACAAGACGCGCTACCACGGTGTGAACAGTGCGACGATGGCCGCCCGCTACAGCTGCGACTACTGTCCGCGGATCTTTCTGCGGAAGCAGGATCGCACCACGCACCAGATGATGGTGCACGCGCGCGATCATGCCGACGCGATCGACGTGTCGCCGGGACCGACGCGGGTGCATTCGAAATCGAAACGGAAGGATTACGTGTGCCGAACGTGCGACGAAGAGTTCGACACGTACCGCATCTGCCAGCGGCACATCTTCGTGCAGCATCCCGCCGTCGAGGGCGGCCCGGCGGTGGACAAACCGATGAAGCTTTGCCACTGTAGCATATGCAATGGGATTTACAAGAAACGGGACGATTGGCACGAGCATCTGAACAACCACCCGAGCGTGCGGCCCCATCACTGCGAACAGTGCATCCGGCGGCGACGGAAGGCATCGAGCCGGAAGCAGGTGCACCGCTGCTCGTACTGTCCGAAGGCGTTCGAGCACAAACCGAACCTGGCGTCGCATCTGCGCATCCACAAGCAGCAGCTGCGGTTCCCGTGCACCGAGTGCGGTGTTATGTACGATCGGTACCGCGATCTGTTGGCGCACCAGAGCCGATACCACTCGCAGGACCCAGCGGATGGTGGGGCGAACCGGGAGCCGCTGCAGAAATGTAACTTCTGTCCGCGCGTCTTTACCCGGCTGCGGGACGTCAAGTACCATCAGGAGCAGGTGCATGCGGATCAAGCGATCCCGATCGAGCAACCCCCCATCAAACCGGAGCCGGAACACTCACCACAGTAA
Protein Sequence: MMKPEQEPEPVVDDDPVDVPNPNAESYCRFCFSENEVEPLFSADGTQASAELLERIYDCIGIRLTKKEYCPSAICWSCTLTMEEFQCFRKRCLKFDALVRRLRPTIKSEQGYGGTTDHHKSFGRQQDKAAKKVANASSEVRSFLCQYCPRTFKQRMYLDQHMWKHRDRVAAEAATNQAINKRSMAVNGSGNGSMVVIKKEPIVASSTPTPPPPPVATTQTGAQVDRPISCEYCPRKFTRRMYYMQHLRRHKPEERLFRCRHCTRSFTSHMRRVGHERKIHGYLSNPKMEEKDSFSCPKCARVFKHRSSLRMHLLNHDGQLPYACDICNCRFYSVSYLGLHKKRYHGPNAARSVANGTSIPCLYCTRWFLRECDRSSHIKQMHADMHASKASAAGFNEMLADCPPADSEGMIDDPEMLPPNVHEPMMVIKEEEPDTAVVGAVGAAAAAGGGVNDSTASLASLANPGAFQFYCYSCAMPFDTEDMYSEHLDDQHPFGGEQLMDQLQPSSSPVELDENGTKVFRCPYCPKTFTRKWSMTQHIPTHLGRKGYKCEYCPAIFTRNEYLRTHRQRKHPTLPETGTYKCSYCPRLFHKARYKKVHERIAHIKKGDVLPDGDDTEESELVALTGAPSGEKLDESSCSIAFGPSSRASDSFDQTSNDAHSVAESGCGSVQPNYSDLEASARLVVVLERMPPELVEQYRWQMELYANMTPEELTAHSSADETSAVDDTLDGDKLEMRDDLEPAPTAPVFKRKRSKFGITLHPCPHCSKLFKTRGALRLHALYHSGELPHRCDECGVQFMRYNQLEYHKTRYHGVNSATMAARYSCDYCPRIFLRKQDRTTHQMMVHARDHADAIDVSPGPTRVHSKSKRKDYVCRTCDEEFDTYRICQRHIFVQHPAVEGGPAVDKPMKLCHCSICNGIYKKRDDWHEHLNNHPSVRPHHCEQCIRRRRKASSRKQVHRCSYCPKAFEHKPNLASHLRIHKQQLRFPCTECGVMYDRYRDLLAHQSRYHSQDPADGGANREPLQKCNFCPRVFTRLRDVKYHQEQVHADQAIPIEQPPIKPEPEHSPQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00106537;
90% Identity: iTF_00103164;
80% Identity: -