Basic Information

Insect: Anopheles farauti
Gene Symbol: -
Assembly: GCA_000473445.2
Location: KI915064.1:599347-602140[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00011 0.0068 16.4 3.9 1 23 327 349 327 349 0.97

2 10 2.3e-06 0.00013 21.7 0.2 1 23 355 377 355 377 0.98

3 10 4.8e-06 0.00028 20.7 3.3 1 23 383 406 383 406 0.96

4 10 8.5e-06 0.0005 19.9 2.9 1 23 412 434 412 434 0.98

5 10 1e-06 6.2e-05 22.8 0.9 3 23 442 462 440 462 0.97

6 10 2.1e-06 0.00012 21.9 0.9 1 23 468 491 468 491 0.97

7 10 3.8e-05 0.0023 17.9 1.3 1 23 497 519 497 519 0.97

8 10 2.1e-07 1.3e-05 25.0 1.9 1 23 525 547 525 547 0.97

9 10 2.9e-07 1.7e-05 24.5 1.6 1 23 553 575 553 575 0.95

10 10 0.00091 0.054 13.5 0.8 1 23 601 624 601 624 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00011	0.0068	16.4	3.9	1	23	327	349	327	349	0.97
2	10	2.3e-06	0.00013	21.7	0.2	1	23	355	377	355	377	0.98
3	10	4.8e-06	0.00028	20.7	3.3	1	23	383	406	383	406	0.96
4	10	8.5e-06	0.0005	19.9	2.9	1	23	412	434	412	434	0.98
5	10	1e-06	6.2e-05	22.8	0.9	3	23	442	462	440	462	0.97
6	10	2.1e-06	0.00012	21.9	0.9	1	23	468	491	468	491	0.97
7	10	3.8e-05	0.0023	17.9	1.3	1	23	497	519	497	519	0.97
8	10	2.1e-07	1.3e-05	25.0	1.9	1	23	525	547	525	547	0.97
9	10	2.9e-07	1.7e-05	24.5	1.6	1	23	553	575	553	575	0.95
10	10	0.00091	0.054	13.5	0.8	1	23	601	624	601	624	0.96

Sequence Information

Coding Sequence: ATGGTGCATTTCTGTAAATTGTGCCAGTTGTTGCACAAAAACATGGACTTCATCCAATGCGATGATTCTAATGTTTGGCTGCTCGAAACGGTGTTTTCAGTGAAGATCACACCGCTCGATGGACGAGTGGAACCGATTTGCCGAAAATGCATACGCAAATACAACAAGGTAATGAAGGATTTAAAGAAATCTAACGGAGGTTTCCCCGTCTCGCGTCAAACATTTGTCGATCATAACAAAATCCAAAACGGTGAGATGGAATCACCGTTTCAGCTATCGAACTCGGAACAGACACCATCGTTGAACTGCCATAATCGATCACTTGAAACACATCCTTACTTAATGGAGGATGAAAGCAAGGAACTTATGTTTACGGCACCGGCATCGGATAAGACAAACGGAAGCCAGAATGGTAGCAATGGAATGACACTGAATATTAGTGGTGAAGCTGCAACGGTCTATCGCATCACGATGGGAGACACCCAGGAATCCTCCGACGACGACAGCTCTGATGGAAAAAGTAGTATTGCCGACGAAGACGACAGTACGGAAGATTCAAGTGAGGACGACGAGGATGATGATGATTGCTGTAGCGTTGATACGGATGACAGTAGCTCAAGTTGTAGCAGTACTAGCAGCACCGGCGGAAGCTCATCAGAAACAGGGGGCAGTTTACGACTGGAAGATCACATCGAAGGAACTGCAGATGAGTCGGCGGTGCTGTACAGTTCATACATGGATGCACCTTTGATGCAGAATTTACCCGAAGGGAGCCTTTTGCAGGGTGCTGTCGATGATGATGTCATTGCTCCTGATGGGGATCGAATGTTTCCGGATAAAGCTCTAATGAATGAAGTTCTCGAACCACTTCAACTAGATGAACCATTGGCCAAAATTGAAGACAATGGAGATCAACACACACCGCTACAAGCGATGGAGCACATAATGGATGAAAAGCAACAACTACACGAGAAACCGTACGCTTGCAGCTACTGCGACAAACGATTTAGCCAGCATTCGAGCAAAAAGATGCATGAACGAGTGCACAGCCAGGAGAAACCGTACCCTTGCCAGGTGTGCATGAAAGCATTCAGTAACGTTAGCAATCTGACGGTACATATGCGTATTCACCAGGGGTTGAAGCCGTACAAATGTGATAAGTGCGATAAATGCTTCGCACAGTCACAGACTCTCAAAACGCACTACATCTCGGCGCACACGGACGTGCGGCCGTTCCAGTGTGATCGATGCCCGAAGTCATACGCGACACTGTCGAATTTGAATAATCACAAACACACGCACCTGGAGGAAAAACCGTTCGGTTGCGACGAATGTGGGAAGCGATTTACGCAAAAATCATCACTCAAAACGCATGCTCTTTCACACAACTCAGAACGGCCGTTTCCCTGCGAAGAGTGCACCAAGTCATTCAACACGCAGGCGATGTTGAATACTCATCGACGTAATATGCACTGCACCGAACGGCCGTTCGCATGTACCAAGTGCAACAAGTCATACGCACAAGAAACGAGACTACGACAGCACATGCTTAGCCATGCGGATGTTAAACCCCATCCGTGCACGGAATGTAGCAAAACGTTCACGACCGCTACCAACCTTCGCATACATCAGCGAGTGCATTCCGGGGAAAAGCCGTACCCGTGTCCAACGTGCGGTAAATGCTTCTCCCAGCGGTCATCGTTGCGGACGCATGAAATCCTTCACCTACCACCAGAATTGCGACCAGAACCGTCGACACCGGTTGGGGTGGGACGGGGAAGGAAAAAGCGCAAGAAAAAGCACGAATGTGGTTTGTGTGGAAAAGGATTTGCGCTACGGGGCCGTTACCGGAATCACATGAAGCAGGTGCACCAAAGAGACGTCCAGGAGGAGGAAGACAGAGACGATAAGTATCTAAGTATGGAAGCCTCCGACGACAGTGGTAGAGACGGTGAATTTGACGACGGTGACGACGGTGATATGAACGAAGGCAAGAAAATCAATCTCAGACAAGTCGCGAACATGTACGCTCAGAATGAGGGAAATGCCGGAAATGCGAGCGTTCCGTTCCAGCAGGAACAGTTCCATTACGGACAGATTATGTCCTAA
Protein Sequence: MVHFCKLCQLLHKNMDFIQCDDSNVWLLETVFSVKITPLDGRVEPICRKCIRKYNKVMKDLKKSNGGFPVSRQTFVDHNKIQNGEMESPFQLSNSEQTPSLNCHNRSLETHPYLMEDESKELMFTAPASDKTNGSQNGSNGMTLNISGEAATVYRITMGDTQESSDDDSSDGKSSIADEDDSTEDSSEDDEDDDDCCSVDTDDSSSSCSSTSSTGGSSSETGGSLRLEDHIEGTADESAVLYSSYMDAPLMQNLPEGSLLQGAVDDDVIAPDGDRMFPDKALMNEVLEPLQLDEPLAKIEDNGDQHTPLQAMEHIMDEKQQLHEKPYACSYCDKRFSQHSSKKMHERVHSQEKPYPCQVCMKAFSNVSNLTVHMRIHQGLKPYKCDKCDKCFAQSQTLKTHYISAHTDVRPFQCDRCPKSYATLSNLNNHKHTHLEEKPFGCDECGKRFTQKSSLKTHALSHNSERPFPCEECTKSFNTQAMLNTHRRNMHCTERPFACTKCNKSYAQETRLRQHMLSHADVKPHPCTECSKTFTTATNLRIHQRVHSGEKPYPCPTCGKCFSQRSSLRTHEILHLPPELRPEPSTPVGVGRGRKKRKKKHECGLCGKGFALRGRYRNHMKQVHQRDVQEEEDRDDKYLSMEASDDSGRDGEFDDGDDGDMNEGKKINLRQVANMYAQNEGNAGNASVPFQQEQFHYGQIMS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00097914;
90% Identity: iTF_00103138;
80% Identity: -