Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: AXCM01000327:28451-31291[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1.3e-06 7.3e-05 22.7 1.1 1 23 274 296 274 296 0.97

2 12 7.6e-06 0.00044 20.2 1.4 1 23 302 324 302 324 0.98

3 12 0.00012 0.0072 16.4 3.9 1 23 330 352 330 352 0.97

4 12 4.8e-07 2.8e-05 24.0 0.1 1 23 358 380 358 380 0.98

5 12 1.3e-06 7.5e-05 22.7 1.3 1 23 386 409 386 409 0.96

6 12 9.2e-06 0.00054 20.0 2.9 1 23 415 437 415 437 0.98

7 12 1.1e-06 6.3e-05 22.9 0.9 3 23 445 465 443 465 0.97

8 12 2.2e-06 0.00013 21.9 0.9 1 23 471 494 471 494 0.97

9 12 3e-05 0.0018 18.4 1.2 1 23 500 522 500 522 0.98

10 12 3.1e-07 1.8e-05 24.6 1.8 1 23 528 550 528 550 0.97

11 12 3.1e-07 1.8e-05 24.6 1.6 1 23 556 578 556 578 0.95

12 12 0.00067 0.039 14.1 0.4 1 23 604 627 604 627 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1.3e-06	7.3e-05	22.7	1.1	1	23	274	296	274	296	0.97
2	12	7.6e-06	0.00044	20.2	1.4	1	23	302	324	302	324	0.98
3	12	0.00012	0.0072	16.4	3.9	1	23	330	352	330	352	0.97
4	12	4.8e-07	2.8e-05	24.0	0.1	1	23	358	380	358	380	0.98
5	12	1.3e-06	7.5e-05	22.7	1.3	1	23	386	409	386	409	0.96
6	12	9.2e-06	0.00054	20.0	2.9	1	23	415	437	415	437	0.98
7	12	1.1e-06	6.3e-05	22.9	0.9	3	23	445	465	443	465	0.97
8	12	2.2e-06	0.00013	21.9	0.9	1	23	471	494	471	494	0.97
9	12	3e-05	0.0018	18.4	1.2	1	23	500	522	500	522	0.98
10	12	3.1e-07	1.8e-05	24.6	1.8	1	23	528	550	528	550	0.97
11	12	3.1e-07	1.8e-05	24.6	1.6	1	23	556	578	556	578	0.95
12	12	0.00067	0.039	14.1	0.4	1	23	604	627	604	627	0.96

Sequence Information

Coding Sequence: ATGGTGCATTTCTGCAAACTGTGCCAGCTGCTGCACAAAAATATGGACTTCATCCAGTGTGATGATTCCAATGTTTGGCTGCTAGAAACAGTATTTTCGGTGAAGATAACGCCGCTGGATGGACGTGTCGAACCAATCTGTCGGAAATGCATTCGCAAGTACAACAAAGTGATGAAGGATCTCAAAAAATCAAACGGAGGTTTTCCGGTTTCGCGTCAAACTTTCATCGAACATAACAAGCTACAAAATGGGGATGGAGAGTCACTTTTTCAGTTCCCAAGTACCGAACAGCCGGCATCTCTCTCAAGCTCCCAAAGTCGATCATTAGAACAGCATCCATATCTGATGGACGACGAAAGTAAGGAACTTATGTTTACTGGGCAGGTGTCTGACAAAACAAACGGAAGTCAAAATGGCATGACACTGAACCTTAGTGGTGAGGCAGCAACGGTCTATCGCATAACAATGGGAGATGCACAGGAATCTTCTGACGAGGACAGTTCCGATGGAAAAAGCAGCATTGCTGATGAGGACGAGAGCTCCGAAGATTCTAGTGAAGACGACGAAGACGATGACGATGACTGTTGCAGCGATGATACGGACGACTCCAGTTCTAGCTGTAGCAGTACCAGCAGTACCGGCGGAAGTTCATCCGAGACAGGCGCTAGTTTACGACTGGAAGACCACATCGACCATCGAAGTGCAGAAGAGTCTGCAGTTTTATACAGCGCATACATGGACGCACCCATAATGCAAAATCTTCCCGAAGGAAGCCTGTTGCAAGGGGTCCACACTCGCACGCATACGGGCGAAAAACCGTATGCATGCGACATTTGCTTCAAGAGCTTCACGCAGGCGTCTAGCTTAAATACGCACAAGCGGCTACATTTCAACGTAAAACCTTTCGTGTGCGAAATATGCCACCAGCAGTACACTAGTGCCGGAAACTATAAAGTACATTTGCGCACACACACGCAAGAGAAACCATACGCTTGCAGTTACTGCGACAAACGGTTTAGCCAACATTCTAGCAAGAAAATGCACGAACGAGTGCATAGTCAGGAAAAGCCTTACCCTTGTCAAGTATGCCTGAAGGCATTCAGTAATGTAAGCAACCTAACCGTGCACATGCGCATCCACCAGGGCTTGAAGCCGTACAAGTGTGACAAATGCGATAAAAGCTTTGCCCAGTCCCAGACTCTGAAGACGCACTACATATCGGCTCACACGGATGTGCGGCCGTTTCAGTGCGATCGTTGTCCGAAGTCGTACGCAACGCTGTCGAATCTAAACAATCACAAACATACACACTTGGAGGAGAAACCATTCGGGTGCGAGGAATGCGGAAAGCGATTTACGCAAAAGTCTTCACTTAAAACGCATGCCCTATCGCACAATACCGAGCGTCCCTTCCCTTGCGAGGAGTGCACCAAATCGTTCAACACGCAAGCCATGTTGAATACGCACCGGCGGAATATGCACTGCACCGAGCGACCGTACGCATGTACAAAGTGCAATAAATCGTACGCACAGGAGACAAGACTTCGGCAGCACATGTTAAGCCATGCGGACGTAAAGCCGCATCCGTGTCAGGAATGTAGCAAAACATTTACCACTGCTACAAATCTGCGCATACACCAGCGTGTCCATTCGGGCGAAAAGCCGTACCCCTGTCCGACTTGTGGAAAATGTTTTTCGCAAAGATCGTCCTTGCGTACGCATGAAATATTGCACCTGCCACCGGAACTGCGACCTGATCCACCGGTAACAGTAGATGTGGGGCATGGGCGAAAGAGACGCAAGAAAAAATTCGAATGTGGGCAATGTGGGAAAGGGTTCACGATACGCGGGCGCTACCTTAATCACATGAAACAGGTACACCAAAGAGATGTGCATGACGACGAAGCCATCGTTGTTCCAGCGTTCCGTTGCAGGAACAGCAGTTCCATTACGGGCAAATACTTTCCGAGCAAAATTAACATAGTCAGTTTCCAGTATCGCAAGCGTGCCGATGAATTCGCCATGATATAA
Protein Sequence: MVHFCKLCQLLHKNMDFIQCDDSNVWLLETVFSVKITPLDGRVEPICRKCIRKYNKVMKDLKKSNGGFPVSRQTFIEHNKLQNGDGESLFQFPSTEQPASLSSSQSRSLEQHPYLMDDESKELMFTGQVSDKTNGSQNGMTLNLSGEAATVYRITMGDAQESSDEDSSDGKSSIADEDESSEDSSEDDEDDDDDCCSDDTDDSSSSCSSTSSTGGSSSETGASLRLEDHIDHRSAEESAVLYSAYMDAPIMQNLPEGSLLQGVHTRTHTGEKPYACDICFKSFTQASSLNTHKRLHFNVKPFVCEICHQQYTSAGNYKVHLRTHTQEKPYACSYCDKRFSQHSSKKMHERVHSQEKPYPCQVCLKAFSNVSNLTVHMRIHQGLKPYKCDKCDKSFAQSQTLKTHYISAHTDVRPFQCDRCPKSYATLSNLNNHKHTHLEEKPFGCEECGKRFTQKSSLKTHALSHNTERPFPCEECTKSFNTQAMLNTHRRNMHCTERPYACTKCNKSYAQETRLRQHMLSHADVKPHPCQECSKTFTTATNLRIHQRVHSGEKPYPCPTCGKCFSQRSSLRTHEILHLPPELRPDPPVTVDVGHGRKRRKKKFECGQCGKGFTIRGRYLNHMKQVHQRDVHDDEAIVVPAFRCRNSSSITGKYFPSKINIVSFQYRKRADEFAMI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100453; iTF_00103138;
90% Identity: -
80% Identity: -