Aepi010639.1
Basic Information
- Insect
- Anopheles epiroticus
- Gene Symbol
- -
- Assembly
- GCA_000349105.1
- Location
- KB671698:13106-15872[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.82 50 4.1 0.5 1 15 48 62 48 65 0.83 2 13 0.00078 0.048 13.6 1.7 2 23 346 367 345 367 0.97 3 13 2.4e-06 0.00015 21.5 0.9 2 23 374 395 373 395 0.97 4 13 0.0003 0.019 14.9 0.4 1 23 405 427 405 427 0.98 5 13 0.95 58 3.9 0.0 3 23 452 479 450 479 0.82 6 13 6.9 4.2e+02 1.2 1.2 2 23 486 507 485 507 0.70 7 13 3.8e-07 2.3e-05 24.0 2.7 1 23 545 568 545 568 0.96 8 13 0.00098 0.06 13.3 1.3 2 23 574 595 573 595 0.95 9 13 1.6e-05 0.00096 18.9 2.2 1 23 600 622 600 622 0.94 10 13 0.00096 0.059 13.3 0.2 2 23 631 653 630 653 0.97 11 13 0.00039 0.024 14.5 0.5 2 20 660 678 659 680 0.93 12 13 3.5e-05 0.0021 17.8 0.4 1 23 691 713 691 713 0.99 13 13 0.00037 0.023 14.6 2.6 1 23 719 742 719 742 0.98
Sequence Information
- Coding Sequence
- ATGGAGCAGTTTGTTAATTGTGTACTGTGCTTGGCTACCGAGCCGCAAAGCTTTCTCAAAGTGTACAGTGAGGAGAAGAATGAGGCTGATATCGCATCGATCATAACAAAACATCTTTGGGTGAAACCGACCGAAGATTCGTACGTGTGCGATGAGTGCTGGAAAAGTCTGAACGATTTTCACGAATTTTACACCAGGCTCGAAACCATACACTATCCACCAGATCCGGAAGATGCGTCATGCAACGTGAAAGACATCCGGCAGTACCTTTTCGAATTTCATCCGGTGGAGGATGTGAAAATTGAAGAATTATCACAAGATGCACAAGAAATAGAGGAAATTGAGTACGAGTATTTGGAAGCGTGTAATGAAGAAACCAATGAGACCGTTAAAGCGGAACGTGTCAGCACCCGTCCCAAGCGTGCTAGCGCAGCACAGGCGAACTATAAGATTGAAGCGGCCGATGCGGAATGGGAGAAGGATTATCTGGCCacgaacgaagacgacaacgacgacgacgaggaggaggaggaggaggacgaggagTACCAAGAAGACGAGAATGATGCCGATTATGAAGCGGATGTGAAGGATGATGTAGACTATCGCGAGGAGGACAATGATGATAGTGAAGTCATTAATTACGATAGTCTCTCTAAGACGAAACAAGAGGACAATATCAAAAAAGAAGCTAGTGAACCCACCATACCACCGAAAAGAGGACGGGGTAGACCTCCGAAGATTAAAAAGGAAGTGGAAATAAAGTCGAAACCGAAGAAGCATCGTGGTCGGGGCAGGAGGCGAAAGGTTTCGGTAAGCAGTAGTGATTCGGAACTGGAGTCCGATGTTGATGAGTACCGTAATACGTCGAAAGACAAAGGAAGAAGATCGCTCGGTTTTCGGCAGCTGCAGGAAAAAATATTCTCGTACGTGGACGAGTTTGTCTGCTACCACTGTCCGGAAAAGGTCGTGTTCGAACGGTTTCATCATGCGAATCTGCATTACAAAACGGTGCACGACGAGCCGGCCTTTCTGCGGTGTCCAAAGTGTAGCAAAAAGTGTTTCACGCCCGGCGGATTCGTGAGCCATATGGAAACGCATGAGGATCCGGAGAGGAATAAGTGTAAAATTTGTGGCAAGGTTACAGATCAACAAATCACGCTTAAAAAGCATATGCGAGCGCATCAGGAGAAGCTGGAGAAAAACTACCCGTACCCGTGCGGTCTATGTTCGCGGCGGTTTGAGGTGAAAGAGAAGCTCGAAAAGCATGAAAGGCTACACGGTAGGAAGGTGATCATCAAGAAGGAGAAGGGCCGGGATCTGGAGCTGCTGGCGTTTTACAAACGTATATATTGTGAAATTTGCGAAGAAAAACAGCCCGGATCGACCTCGTTCGACAACTTCTGGGATCTGAAGGTACACATGGGCAATGAACACAACAAAACGCCCTACCTGAAGTGTCCCATTTGCTACAAGAAGAACGTGTGCCGCCAGCAGCTGATGGTGCACGTGGACATGCATAATAATCCCGAAAACTATCGCTGTGAAGTGTGCAAAGAAGTTCATCAAAATCTTGAACGACACATGATTAAGGCGCACAGCCCGGAAACGTCGTTCCCGGAGGAGAAAAACTACAGCTGCGAGCATTGTGGAAAAATGTTCAAATACCAAACGAACCTTAAGAGTCATATCGATCGTGTGCACGGCGTTAAGGATGTGTCCTGTGACATATGCCATAAATTCTTCAACAGCAAAGCGTTAAGTGCTCACAAGCGGTCAGCCCACACTGATGAAAAGTTTATGTGCGAACATTGCCCGAAAATGTTCAAAACGCGCAGCGGGCTCGAATCGCACAAGAGTGACCACGATGAAACGTTGCGCAAATCGGTTAAGTGTACCATTTGTGGCAAGGAGATGCGGCGCGGTGCCAGCATGGCGAAGCACATGAAAACGATCCACTCGCAGGAGGATCCGGTCAGTTGCGATCTCTGTGGCAAGGTGTTCCGCACCACGTTCCATATGCTGCGGCATCGGGCAAACACGTGTTCGGCTACGATCGATTCGCGCCCGTACAAGTGTGAGGTGTGCGGTAAGGGCTTTGCCATGAAACTCACAATGACCGAGCATATGACGACGCATACACGCACTAGCCTGTATCAGTGCGCGTTCTGCTTCAAAACCTTTGGCTACATTTCGAATCTGTACAAGCACCGGAAGAAGGCACATCCGCTCGAATGGCAGGAGGTACAGGCGCGCCCAGAGCAAGGGATCGCAACGGTAATCGAAATACGCAATTAA
- Protein Sequence
- MEQFVNCVLCLATEPQSFLKVYSEEKNEADIASIITKHLWVKPTEDSYVCDECWKSLNDFHEFYTRLETIHYPPDPEDASCNVKDIRQYLFEFHPVEDVKIEELSQDAQEIEEIEYEYLEACNEETNETVKAERVSTRPKRASAAQANYKIEAADAEWEKDYLATNEDDNDDDEEEEEEDEEYQEDENDADYEADVKDDVDYREEDNDDSEVINYDSLSKTKQEDNIKKEASEPTIPPKRGRGRPPKIKKEVEIKSKPKKHRGRGRRRKVSVSSSDSELESDVDEYRNTSKDKGRRSLGFRQLQEKIFSYVDEFVCYHCPEKVVFERFHHANLHYKTVHDEPAFLRCPKCSKKCFTPGGFVSHMETHEDPERNKCKICGKVTDQQITLKKHMRAHQEKLEKNYPYPCGLCSRRFEVKEKLEKHERLHGRKVIIKKEKGRDLELLAFYKRIYCEICEEKQPGSTSFDNFWDLKVHMGNEHNKTPYLKCPICYKKNVCRQQLMVHVDMHNNPENYRCEVCKEVHQNLERHMIKAHSPETSFPEEKNYSCEHCGKMFKYQTNLKSHIDRVHGVKDVSCDICHKFFNSKALSAHKRSAHTDEKFMCEHCPKMFKTRSGLESHKSDHDETLRKSVKCTICGKEMRRGASMAKHMKTIHSQEDPVSCDLCGKVFRTTFHMLRHRANTCSATIDSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQEVQARPEQGIATVIEIRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00093670;
- 90% Identity
- -
- 80% Identity
- -