Adir001745.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- -
- Assembly
- GCA_000349145.1
- Location
- KB672979.1:11963676-11966522[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.3 2.4e+02 2.0 2.3 1 14 48 61 48 64 0.82 2 13 8e-05 0.0045 16.8 1.1 2 23 351 372 350 372 0.97 3 13 2.7e-06 0.00015 21.5 0.9 2 23 379 400 378 400 0.97 4 13 0.15 8.2 6.6 3.0 1 23 410 432 410 432 0.96 5 13 1.7 94 3.3 0.1 3 23 457 484 456 484 0.79 6 13 7.8 4.3e+02 1.2 1.1 2 20 491 509 490 512 0.64 7 13 4.4e-07 2.4e-05 24.0 2.5 1 23 550 573 550 573 0.96 8 13 0.029 1.6 8.8 3.8 3 23 580 600 578 600 0.94 9 13 2.4e-05 0.0013 18.5 1.5 1 22 605 626 605 627 0.91 10 13 0.0026 0.14 12.1 0.3 2 23 636 658 635 658 0.97 11 13 9.9e-05 0.0055 16.6 1.1 3 20 666 683 664 685 0.93 12 13 4e-05 0.0022 17.8 0.4 1 23 696 718 696 718 0.99 13 13 0.00043 0.024 14.6 2.6 1 23 724 747 724 747 0.98
Sequence Information
- Coding Sequence
- ATGGACCAATCCGTAACGTGCGTGCTTTGCCTGTCCGGCGAGGCGCAAAGTTTCCTCAAAGTGTACATTGACGAAAGCCAAGAGAGTGATATCGCGGCCACCATAACAAAACATCTCTGGGTAAAACCGACGGAGGATTCGTACGTTTGTAACGGATGCTGGAAATGTTTGGATGATTTTCATCAATTCTACATCCGTCTGGAGAGCATACACTCCGAGGACCAGGAGGAAGCGCAGTGTGACGCGAAAGATATCCGGCAGTATCTCTTCGAGTTTCATCCCGTGGAGGACATTAAAATTGAACAGCTGGACATAGAAGTGGAAGATGGTGAGCAATCGATCAGAGAATGTGAAGACGAGGAAGGCGACAATACGGACCGTTCCAGCAGCCGGCCGAAAAGAGCAAGTGCCGTACAAGCAACCTACCGCATCGAAGAGTCCGAAGCGGAATGGGAGGAAGATTACCTAGCCAcaaacgacgatgacgaccaAATGAACGATGCAGATTACGATGAGCTGGAAGAAGTGAAGAAGGAGCGTAACATAAAagaggagcaggaggaagaggatgacgacgatgaggaaGTTATTAACTACGACAAACTAAACAGTGCGAAAGACGCGGTGTCAGCTGACCGTGACTCGAATCCCGTCGAAGATACGAAACCATCGCTCGCCGACCTAACGCCAGTGAAGCGAGGCAGAGGACGACCGCCGAAGGTGAAAACGGAAAGCACCAGCAAACCGGTGGTGCCTGCCAAAAAGCAAACTCCCGGCCGGCGTGGACGCCGACGAAAGGTGTCGATCACCAGTAGCGACTCGGATCTGGACTTTGAGTCGGATGATGAAGTGCTTGAGGACAAATACCGCAGGTACTCGAAGGGCGGGCAGACGAAAAAGTCACCCGGTACCCGTGAGCTGCGCGATAAGCGAATCTTTTCGTACGTGGATGAATTCATCTGCTACTACTGCCCGGAGAAGATCCTGTTCGAGCGGTTCCATCACGCGAACCAGCACTACAAGCAGGTCCACAAAGAGCCCGCCTTTCTGCGGTGTCCCAAGTGTGGCAAGAAGTGCTTCACACCCGGTGGCTTCGTGAGCCACATGGAGACGCACGAGGATCCGGATAGAAACAAGTGTAAAATATGTGGCAAGGTCACGGATCAACAGATCACGCTGAAAAAGCATATGCGGGCGCATCAGGAGAAGCTGGAGAAAGACTATCCGTTCCCGTGCAGCCAATGTACGCGCCGCTTCGAGCACGAGGAGAAGCGCGACAAGCACGAGCGCCTGCACGGCCGGAAGGTGGTCATCAAGAAGGAGAAGGGACGCGATCTGGAAGTGCTGGCGTTCTACAAGCGCATCTTCTGTGAGATATGTGAGGAGATCAAACCGGAATCGACCTCGTTCGACAACTTCTGGGATCTGAAGGTGCACATGGGCAACGAGCACAATAAGGCACCGTACCTGAAGTGTCCGATATGCTTCAAAAAGAACGTCTGCCGCCAACAGCTGATGGTGCACGTGGACGTGCACAATAATCCAGAAAACTATCGGTGCGAGGTGTGTAAGGAAATCCATCAGAATCTAGAGAAGCACATGATCAAGGCGCACACAGCGGCCACGACGATACCGGACGAGAAAAACTACAGCTGCGAGCATTGTGgcaaaatgttcaaatatcAAACCAACCTGCGGAGTCACATCGATCGTGTGCACGGCGTTAAGGACGTGTGCTGTAACATCTGCAACAAATACTTCAATCATAAAGCACTGAGTGCTCACAAGCGGTCGGCTCACACGGACGAAATGTTTATGTGCGAACACTGcccgaaaatgttcaaaacaCGCAGCGGTCTCGAATCGCACAAGGGCGACCACGACGAGACGCAGCGCAAATCCGTCAAGTGCAACCTGTGCGGCAAGGAGATGCGTCGCGGTGCCAGCATGGCGAAGCATATGAAAACGATCCACTCGCAGGAGGACCCGGTCAACTGCAACCTGTGCGGGAAGACGTTCCGCACCTCGTTCCACATGTTGCGCCACCGGGCGAACACGTGCGCGGCCACCATCAACAGCCGGCCGTACAAGTGCGAGGTGTGCGGCAAGGGCTTCGCCATGAAGCTGACGATGACCGAGCACATgacgacgcacacacgcaccagccTCTACCAGTGCGCGTTCTGCTTCAAAACGTTCGGCTATATCTCGAATCTGTACAAGCACCGCAAGAAAGCGCACCCACTCGAGTGGCAGGAGGTGCAGGCGCGTCCCGAGCAGGGCATCGCTACTGTAATCGAAATACGTAACTAA
- Protein Sequence
- MDQSVTCVLCLSGEAQSFLKVYIDESQESDIAATITKHLWVKPTEDSYVCNGCWKCLDDFHQFYIRLESIHSEDQEEAQCDAKDIRQYLFEFHPVEDIKIEQLDIEVEDGEQSIRECEDEEGDNTDRSSSRPKRASAVQATYRIEESEAEWEEDYLATNDDDDQMNDADYDELEEVKKERNIKEEQEEEDDDDEEVINYDKLNSAKDAVSADRDSNPVEDTKPSLADLTPVKRGRGRPPKVKTESTSKPVVPAKKQTPGRRGRRRKVSITSSDSDLDFESDDEVLEDKYRRYSKGGQTKKSPGTRELRDKRIFSYVDEFICYYCPEKILFERFHHANQHYKQVHKEPAFLRCPKCGKKCFTPGGFVSHMETHEDPDRNKCKICGKVTDQQITLKKHMRAHQEKLEKDYPFPCSQCTRRFEHEEKRDKHERLHGRKVVIKKEKGRDLEVLAFYKRIFCEICEEIKPESTSFDNFWDLKVHMGNEHNKAPYLKCPICFKKNVCRQQLMVHVDVHNNPENYRCEVCKEIHQNLEKHMIKAHTAATTIPDEKNYSCEHCGKMFKYQTNLRSHIDRVHGVKDVCCNICNKYFNHKALSAHKRSAHTDEMFMCEHCPKMFKTRSGLESHKGDHDETQRKSVKCNLCGKEMRRGASMAKHMKTIHSQEDPVNCNLCGKTFRTSFHMLRHRANTCAATINSRPYKCEVCGKGFAMKLTMTEHMTTHTRTSLYQCAFCFKTFGYISNLYKHRKKAHPLEWQEVQARPEQGIATVIEIRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00106557; iTF_00100519;
- 90% Identity
- iTF_00106557; iTF_00100519;
- 80% Identity
- -