Basic Information

Insect: Anopheles dirus
Gene Symbol: -
Assembly: GCA_000349145.1
Location: KB673534.1:5067241-5072061[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00066 0.037 14.0 6.1 1 23 237 259 237 259 0.98

2 11 1.6e-06 8.7e-05 22.2 0.2 1 23 294 316 294 316 0.98

3 11 3.6e-07 2e-05 24.2 0.8 1 23 322 344 322 344 0.98

4 11 8.1e-07 4.5e-05 23.1 3.5 1 23 350 372 350 372 0.98

5 11 0.00019 0.011 15.7 1.0 1 19 378 396 378 399 0.95

6 11 1.2e-05 0.00069 19.4 0.8 1 23 405 427 405 427 0.98

7 11 1.4e-07 7.8e-06 25.5 1.1 1 23 436 458 436 458 0.99

8 11 7.6e-07 4.2e-05 23.2 0.7 1 23 464 486 464 486 0.99

9 11 0.012 0.66 10.0 0.2 1 19 493 511 493 512 0.95

10 11 0.00019 0.01 15.7 1.1 1 23 614 636 614 636 0.98

11 11 1.6 91 3.3 0.0 1 11 691 701 691 705 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00066	0.037	14.0	6.1	1	23	237	259	237	259	0.98
2	11	1.6e-06	8.7e-05	22.2	0.2	1	23	294	316	294	316	0.98
3	11	3.6e-07	2e-05	24.2	0.8	1	23	322	344	322	344	0.98
4	11	8.1e-07	4.5e-05	23.1	3.5	1	23	350	372	350	372	0.98
5	11	0.00019	0.011	15.7	1.0	1	19	378	396	378	399	0.95
6	11	1.2e-05	0.00069	19.4	0.8	1	23	405	427	405	427	0.98
7	11	1.4e-07	7.8e-06	25.5	1.1	1	23	436	458	436	458	0.99
8	11	7.6e-07	4.2e-05	23.2	0.7	1	23	464	486	464	486	0.99
9	11	0.012	0.66	10.0	0.2	1	19	493	511	493	512	0.95
10	11	0.00019	0.01	15.7	1.1	1	23	614	636	614	636	0.98
11	11	1.6	91	3.3	0.0	1	11	691	701	691	705	0.86

Sequence Information

Coding Sequence: ATGGCAGAAGATTTATcgatcaataaaaataagatCTTCACCCAGCGGTACGGAAACAGTAACAACGATATTTGTCGATTGTGTTTGAAGAATGAAGCCCACATGGAACCGCTGTTCTATTCCAACCTCTTCCCCAACATTCTACTCACGAAGAAAATATACGACTGTACCTCTATTCAGATCATCTATGAGCGCAATCTGCCAATGTTCGTGTGTAAACTTTGCGCCAACAAGCTGGACGAGTACGTCCGCTTCCGGGATCGGTGCATTGCGAACGACGAGTTCCTGCGCAACGCGCTGGCGGCATTCGGTGCGAGCGGTGGGAGCTGTGCCGGCACGATAAAGACCGAACCGGAAGAtgcgccgctgccaccgccattGCCACCGCAGGCACCGGCGAGCGCGAAGTTCGCCCAATGTCTCGGCGTGACACCGATGGAGCTGAACTGTGCGCTGGTggcagcggctgccgctgctgccggccaTCAGGGCAGCAAGCGGGAACCTCCGGACGTGGAAGACCACCATCATGGCGGGTACGGACACCAGTCGGACGTACCGTCTCCCAGCCACCCTGGTTGCGGGCGGCTGACGGTCGATGACTTACCCCACAAACAGACGCTCGATAATCGATACCGGAGTGCGGAGGAGGACGACATACCCACCGACGATGCCTACGGCGAGCGCAATCCGGACGCCGAGGACCCGTACGTGTGTGACGTCTGCTCGAAGTCGTTCACGATACGCCACCATCTGCTGGTCCATCGCCATACGCACCTGGACAATCACTCGGTCCAGATGAACGGTCTGCTGCACGGTGCTGGGCCAGacttcggtggtggtggcgttggtgcaGCCGCACCGGGCGGGAAACAATCGTACAACTGCCCCAAGTGCGCCAAAGTGTTCGTCAACAAGGGTAACCTGCTGAACCATCTAGAGACGCACACGAACGAGAAGAGCTACGCGTGCGACATCTGCACGAAGACGTTCAAGTACAACGTGCAGCTGCGGCTGCATATGCGCATCCACACGGGCGAGCGACCGCACAAGTGCGAGATCTGCAACCGCGGCTTCTCGCAGCTCTCGAATCTGCGCTCCCACCGGAAGACTCACTCGAAGGTCAAACCGTACAAGTGCCACCTGTGTCTGAAGAGTTTCACCGTGCTGGACAACCTCACAGCGCACAGTACAAAATGCCTGAAGGACAAGTTCCGCTGTACGCTCTGCTCGAAATCGTTCGCCAAGGAGGGTAACCTGCTGTCGCACCTGCAGTCGCACAGCGAGGGCATCGTGGAGAAGATGTTCAAGTGCGAGATGTGCCCGAAGAGCTTCAAGAACAAGGAGGACTGGAAGCGGCACGTGCGCGTGCACACGGGCGAGAAGCCGTACACGTGCGACATCTGCTCGAAAGGGTTCGCGCAGAAGGCGAACCTGCTGTCCCACCGGAAGACGCACCTGAAGCCGAACGTCGTGTACAAATGCGAACGATGCGCGCGTACCTTCCGCTCGCAGAAGGTGCTGGAACTGCACGCGCCGAAGTGTTCCGGTGCGGTCGGCCCGGGCGAACCCGGTATTCCTTCCGCTCCGGTTACGCCGGTATCGGAGTCGATTCCGGACTCGCCCAGTCCCGGGACCGCCATCACGCTGTCGACGGCGGCATCGTCGGAGGCGGCGTCGGCCACCAGCACGCCGACGCTGTCGGAGGCGCTCTCCGATCTGCTGCGGTACGAGATAGCGCTGCGTGCTCCGCTGGAGCTCCAGCAGATGCTTCTCGGGCATATCGATCGGAAAAAGGGCCACAATGGTACCGGTGGGGGGAAGGCGGCGGGACGGCGCTACCGATGTGACGTGTGCTTCAAGGGCTACTCCCAGTACCCGTCGCTGATCAAGCACCGGAAGCTGCACTTCAAGGTACCGCCGCTGGTGAAGGTGCTGGCGGGGAAGGGACATCGGCACGAGGACTTCGAGGACACCGACCGGCGGGAGCACTGCGAGGACGAGCCGGACGGCGGCGTGGAGCACCAACGCCGGACGCCGGTGCCGCACGATCCGACGACCGAGCGCCCGTACAGCTGTGATATATGCGGCGGAAGATTTGCGGCAGCATCTGCGCACCCACCCGACCGCTGCCGGCAGGAGCTTCAGCTGCGAGTACTGCTCGAACCGCTTCCGCTCGAACGAGGACCTGAAGCGGCACCGACGGTCGCACACCGGCGAACGGCCGTTCCGGTGTCCACGCTGCCCGAAGGCGTTTACCCAGCAGTCGAACATGCGGGCACACACGAGGATCCACGACCGGCCAGTGCCGGCGCCAGAACCACCCTCATCCAGCCAGTGACCGAGCGGCCGGGATGTCTGGATGTGTAA
Protein Sequence: MAEDLSINKNKIFTQRYGNSNNDICRLCLKNEAHMEPLFYSNLFPNILLTKKIYDCTSIQIIYERNLPMFVCKLCANKLDEYVRFRDRCIANDEFLRNALAAFGASGGSCAGTIKTEPEDAPLPPPLPPQAPASAKFAQCLGVTPMELNCALVAAAAAAAGHQGSKREPPDVEDHHHGGYGHQSDVPSPSHPGCGRLTVDDLPHKQTLDNRYRSAEEDDIPTDDAYGERNPDAEDPYVCDVCSKSFTIRHHLLVHRHTHLDNHSVQMNGLLHGAGPDFGGGGVGAAAPGGKQSYNCPKCAKVFVNKGNLLNHLETHTNEKSYACDICTKTFKYNVQLRLHMRIHTGERPHKCEICNRGFSQLSNLRSHRKTHSKVKPYKCHLCLKSFTVLDNLTAHSTKCLKDKFRCTLCSKSFAKEGNLLSHLQSHSEGIVEKMFKCEMCPKSFKNKEDWKRHVRVHTGEKPYTCDICSKGFAQKANLLSHRKTHLKPNVVYKCERCARTFRSQKVLELHAPKCSGAVGPGEPGIPSAPVTPVSESIPDSPSPGTAITLSTAASSEAASATSTPTLSEALSDLLRYEIALRAPLELQQMLLGHIDRKKGHNGTGGGKAAGRRYRCDVCFKGYSQYPSLIKHRKLHFKVPPLVKVLAGKGHRHEDFEDTDRREHCEDEPDGGVEHQRRTPVPHDPTTERPYSCDICGGRFAAASAHPPDRCRQELQLRVLLEPLPLERGPEAAPTVAHRRTAVPVSTLPEGVYPAVEHAGTHEDPRPASAGARTTLIQPVTERPGCLDV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00100445;
90% Identity: -
80% Identity: -