Adir004540.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles dirus
Gene Symbol
-
Assembly
GCA_000349145.1
Location
KB672490.1:7640450-7657549[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0014 0.076 13.0 1.2 2 23 50 71 49 71 0.97
2 16 6.1e-05 0.0034 17.2 1.9 1 23 77 99 77 99 0.98
3 16 1.2e-05 0.00068 19.4 0.2 1 19 105 123 105 127 0.93
4 16 7e-07 3.9e-05 23.3 2.3 1 23 133 155 133 155 0.98
5 16 1.8e-06 0.0001 22.0 0.9 1 23 161 183 161 183 0.98
6 16 1.2e-06 6.5e-05 22.6 1.0 1 23 189 211 189 211 0.98
7 16 4.3e-07 2.4e-05 24.0 0.3 1 23 217 239 217 239 0.98
8 16 3.4e-06 0.00019 21.2 0.3 1 23 245 267 245 267 0.97
9 16 2.7e-07 1.5e-05 24.6 0.4 1 23 273 295 273 295 0.98
10 16 2.3e-06 0.00013 21.7 0.3 1 23 301 323 301 323 0.98
11 16 2.3e-06 0.00013 21.7 0.3 1 23 329 351 329 351 0.97
12 16 8.5e-07 4.8e-05 23.1 0.3 1 23 357 379 357 379 0.98
13 16 4.6e-07 2.6e-05 23.9 0.3 1 23 385 407 385 407 0.98
14 16 3.3e-07 1.8e-05 24.4 1.2 1 23 413 435 413 435 0.98
15 16 1.8e-06 0.0001 22.0 3.4 1 23 441 463 441 463 0.97
16 16 0.1 5.8 7.1 0.3 1 21 482 502 482 503 0.96

Sequence Information

Coding Sequence
ATGTTCTACCCGCTGCAAACTCAGTTCGAGGATGGCGTAATTGAGCTGACACGTTCGGAAATGCTCCAGCAGGATCCATTGGCGGACAATAAGCACTTCGTCGTATCCCTTTCGCTAGGAAATACGCTCATCAATCTCAACAAAATCAAGTGTCCTCAATGTCGGAAGCGCTTTGATACGATGGAGGAAATGGAACAGCACCGGACCAAGCATTTGACAGAGAACAAGTTTAAGTGCGAAATTTGCAGCAAGGAGTTTCCCAGCCATAGTTCCATGTGGAAGCACACCAAGGCGCACACCGGCGAACGTCCTTTCGTGTGCCAGATATGCAACAAAGGCTTCACCCAACTGGCCAACCTCCAACGACATGATCTCGTCCACAACGGACTTAAACCCTTCAAATGTCCAATCTGTGAGAAATGTTTCACTCAACAAGCGAACATGCTGAAGCATCAACTACTGCATACTGGACTTAAACCGTACAAATGTCCCGTGTGCGAGAAAGCGTTCTCGCAACATGCAAACATGGTCAAACATCAAATGCTTCACACAGGTTTGAAGCCCTACAAGTGTCCCGTGTGCGAAAAGGCATTTACGCAGCACGCCAACATGATCAAGCATCAAATGCTCCATACTGGTCTAAAGCCATATAAATGTCCTGTTTGTGAGAAGGCTTTCACCCAGCAGGCCAACATGGTGAAACATCAAATGTTGCACACCGGCGTGAAACCGTACAAATGTTCCACCTGTGGAAAGGCTTTTGCCCAGCAGGCCAACATGGTCAAACACGAGATGCTTCATACCGGTATCAAACCGTACAAGTGTCCCACCTGTGACAAAGCATTTGCCCAGCAAGCAAACATGATGAAACATCAAATGTTGCATACGGGATTGAAGCCGTACAAATGCGGTACATGCGACAAAGCGTTTGCCCAGCAGGCCAATATGGTCAAACATCAGATGCTTCATACGGGTTTAAAACCGTACAAATGCAATACCTGTGGCAAGGCATTCGCACAGCAGGCCAACATGGTCAAACACGAGATGCTTCATACCGGAATCAAACCCTACAAATGTTCCGTTTGCGATAAAGCCTTTGCCCAGCAGGCCAACATGGTCAAACATCAGATGCTCCACAGCGGAATCAAACCGTACAAGTGCCCCACTTGCGATAAAGCATTTGCCCAGCAGGCAAACATGGTTAAGCATCAGATGCTCCATACGGGAGAAAAACCGTTCAAATGCAAAAGCTGTGATAAGGCTTTCTCGCAAAATGCCAACCTGAAGAAGCACGAAATGGTACACCTCGGCATCCGGCCGCACACCTGTCCGCTGTGTACGAAGTCCTACTCGCAGTATTCGAACCTGAAGAAGCATTTGCTCAGCCACCAGAAGCAAGCGATcaagcaggagcagcagaacGGGCAGGTGATGGCTATTCTCTACAGCTGCCAGTCGTGCAAGATGCAGTTTGAGGATATCATCGAGTTCGAACGCCACACCAGACAGTGCGGCATCAACAgcgtgcaacagcagcagcagcagcaacaccagcagcaccagcaacagcagcagcagcaacagcaacagcacagcGTGAAGCTGGAGAACATCAAGAGCGAAATCGACATCGACGGAAGTTCCAGTTCGGGCATGCAGCAGCAcatcgtcaccaccaccaccaacggcacCATCACGAACGGTGGCGGCGTCAGCCAGTCGCAAACGCCGACCCCGATGCACATCCCGTCGGCCATCCTCACCTCCGTCATCTCGTCGTCGGTCGGGGCGAACGTCGTAACGCCGCACAACCTGGTCGTCCCGtccgcacactcacaccacgGGCACATTACGTCGAACGGGGGCACCATCCTGGTCGGAGGCATCCCGACCGGACACCCCCActcccaacagcagcacacccCACCGGGCGTTGGGTtgtcacagcagcagcattctcACGcccaacagcaccaacagcaggctcaccagcagcagcagcagcagcaacagcaacagctgtCCCCGCTCGgcacacaccaacagcatcagctggtgctgcagcagcagcacaacctGCCGAtccatctgcagcagcagctgtcgcACCACCTGATCAGCTCCCACCTGCCCCACCCGCAGGATCACGGTCCGGGCGggacgggcggcggcggcggcgccgaACTGCACCATCAGGTGAACTTCCACCATCCGCACATCTCGCACCTGCCGAACATCTCGCACAAGATCCTGTCGCCGCTGTTCCACATTCCGCCcttcaacaacaaccaccacagcACATAA
Protein Sequence
MFYPLQTQFEDGVIELTRSEMLQQDPLADNKHFVVSLSLGNTLINLNKIKCPQCRKRFDTMEEMEQHRTKHLTENKFKCEICSKEFPSHSSMWKHTKAHTGERPFVCQICNKGFTQLANLQRHDLVHNGLKPFKCPICEKCFTQQANMLKHQLLHTGLKPYKCPVCEKAFSQHANMVKHQMLHTGLKPYKCPVCEKAFTQHANMIKHQMLHTGLKPYKCPVCEKAFTQQANMVKHQMLHTGVKPYKCSTCGKAFAQQANMVKHEMLHTGIKPYKCPTCDKAFAQQANMMKHQMLHTGLKPYKCGTCDKAFAQQANMVKHQMLHTGLKPYKCNTCGKAFAQQANMVKHEMLHTGIKPYKCSVCDKAFAQQANMVKHQMLHSGIKPYKCPTCDKAFAQQANMVKHQMLHTGEKPFKCKSCDKAFSQNANLKKHEMVHLGIRPHTCPLCTKSYSQYSNLKKHLLSHQKQAIKQEQQNGQVMAILYSCQSCKMQFEDIIEFERHTRQCGINSVQQQQQQQHQQHQQQQQQQQQQHSVKLENIKSEIDIDGSSSSGMQQHIVTTTTNGTITNGGGVSQSQTPTPMHIPSAILTSVISSSVGANVVTPHNLVVPSAHSHHGHITSNGGTILVGGIPTGHPHSQQQHTPPGVGLSQQQHSHAQQHQQQAHQQQQQQQQQQLSPLGTHQQHQLVLQQQHNLPIHLQQQLSHHLISSHLPHPQDHGPGGTGGGGGAELHHQVNFHHPHISHLPNISHKILSPLFHIPPFNNNHHST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00102068;
90% Identity
iTF_00099367;
80% Identity
iTF_00099367;