Adir009853.1
Basic Information
- Insect
- Anopheles dirus
- Gene Symbol
- Hr39
- Assembly
- GCA_000349145.1
- Location
- KB673423.1:3475712-3506370[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.12 7.4e+02 -1.3 0.4 119 160 56 96 45 128 0.68 2 4 1.2 7e+03 -4.5 2.2 66 132 388 403 357 436 0.39 3 4 3.7e-08 0.00023 20.2 0.0 1 21 588 608 588 615 0.93 4 4 3.2e-78 1.9e-74 251.0 0.1 175 408 722 951 698 951 0.94
Sequence Information
- Coding Sequence
- ATGAGAATAATGACATCGACCGAAGTGAACGGAGGCGGTGGCACACCAGCGTCGACAACGACGACCACAACGAGCCGCGGCGGAAACGTGTCCGTGACGGCGATCAACTgcgacgatggcggcggcggtgtgaGCGTTCCGCTGGACGTCAGCGGTAGCGCGATGAGCGCGGCAgtcaaacacaacaacaataacaatagtatcagcaacaacaacaacaacagcgcgaCTACCGGCAGCACCAACAGTAACactgtcaacaacaacagcacgacGAGCAGTTCCGGTGGCGGCAGTCCTGGCGCCATCTTTGGAAACGTGAGCGGAGGCATCCGGATCACCGTGCCGAAGATGGAGGAATCGGACGAGTCGGACACGGAGCTGTCGAACATTGAGAAaacggccgccgccgccgccgtactAACGAACGGGGTTAGCATGCGCGAGGAACGGAGCGCCAGCAAGAGTCTTCCGCGGCCCATGTCCTGGGAGGGTGAGCTGTCGGAGCCGGAGGAACCGATGCTGGTGGACAACGAAAACTCGAGCTGCAGTTCACccggcggtgttggtggtggtagcaaGCTGGTCATTGCACCAATCGACCCATCCCCGATAGCGATGATTGTGCCGAAACGGGAAGAGGACACAGAGACACCCGCGTCCGGGCCGGGGATTACGGAACCGCTGGCACTTACTGCAACTTCCGGCAAcggtgtgggtggtggtgttggtggcgttggctTCAACCTCTCCACGCACGGCAACAGTCAAGTGGGTGGTGGGACGGCATCCATCCGGAATCCGCACAGTGGCAGCAACACCGGGAGTAGCAGCTCCAGCAACTCACCGCTCCCGAACCGGCTGCTGATCAAACCGGAAGCGGGCCTTCCGCTCATCAACCCGGGGCTGGCGTACAGCGTGTCCGGGCTCGGGAACACATCCTCCAACATTCCAACGTCGTCCAAGAAGGGACTGCCGGACGTGATAAACCTAAAGTACGAACTACCGCCaggtggcgttggtggcgatcctggcggcggtggtggcactGCCTTACCACCGGGCGCGATACACTCCCCGCTGCTCGTCCGCTCGAAGACTACGCTACTGCCCGCGAATCCCAGCCCGGATTCGGCCATCCACTCGGTGTACACGCACAGCTCGCCGAGCCAGTCGCCACTCACGTCCCGCCATGCACCGTACACGCCATCACTCAGTCGCAACAATAGTGACGCGTCGCACAGCAGCTGCTACTCGTACAGCTCCGAGTTCAGTCCGACGCATTCGCCCATCCAGGGCCGGCATAGTATcttcgctggtggtggtggtggtggcggtggcggcggaggaggtggtggtggcagtgcgTCTTTCAATGGATCACCGTTGCATCACTCAGTATTATACAAACCGATGCTGgacagcgagcagcagcagcaggcactgAAGCagctggcggcggcagcggcggcagccgccCAGGAGGAACCCCTGTACGATGGGGAGCACCTGCCGTCGCCCGGTATTTCCCGGCAGCAGCTTATCAATAGCCCGTGTCCAATCTGTGGCGATAAGATATCCGGCTTCCACTACGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGTACGGTCCAGAACCGTAAGAACTACGTGTGCCTTAGGGGGGCGGCCTGCCCGGTGACGATAGCGACGCGCAAAAAGTGTCCCGCCTGCCGGTTCGAGAAGTGCCTTCAGAAGGGTATGAAGCTGGAAGCTATTCGCGAGGACCGAACACGCGGAGGACGCTCGACTTACCAGTGCTCGTACACTCTGCCCGGCCCGCTGGTGAATGCGGCCGGTGGTGCAATGCAAGCCGGAGATTCCCCCGGAGCTGGGCCATTCCCGTACGGTGGTACGATGCGATCACCGTACGTTGGAGCGGCTGGGCCGGGAGGCGGTGTTGGTATGGGCCAACAGTTGAAGGATGCTTCCGAGGGTGGCATGATGATGGGCGGTGGACCAGGATCGCTTGGGGGTGCGAATGGCGGCATGAATGGCGTCGGAAATGGGACAGGATTGGATATAGGAGCAGGCACAGGGAGCATGCAGCCAGGCATTCCAGTTCTGCTGCAGGAAATTATGGATGTTGAGCCACTGTGGCAGTACAACGCCCAGGAGCTGGCTCGGCTCAACCAACCCGTGACGAATGTGAGCAGCTCGGCGATCGCCAACAATCCCATCCTGTCCAGTGCCGGCATCTCGTCCGACAGCAGTCCCGATCTGATCGCGGAACTCTGCAACATTGCCGACCATCGACTGTACAAGATCGTCAAGTGGTGCAAGAGCCTGCCACTATTCAAACACATTTCCATCGACGACCAGATCTGCCTGCTAATCAACTCTTggtgcgagctgctgctgttctccTGCTGCTACCGTTCGATCTCCACACCCGGGGAGATCAAAATTTCCCTCGGGAAATCGATCACATTGGATCAGGTTAACAATAGTGGCCTGCAGACTTGCATCGAGCGGATGCTGAACCTGACCGACCACCTGCGACGATTGCGTGTCGATCGGTACGAGTACGTGGCGATGAAGGTGATCGTGCTGCTCTCCTCGGACACGTCGGAGCTGAAGGAGTCCGAGAAGGTGCGGTCGAGCCAGGAGAAAGCACTGCAGGCACTGCAAGCATACACGCTGGCCCACTACCCGAAATCGCCAGCCAAATTCGGAGAGCTACTGTTACGCATTCCCGAGCTACAGCGCACGTGTCAGGTTGGAAAGGAGATGCTAACGATCAAGCCGAAGGACGGCGAGGAACCGTCGTTTAACCTGCTAGTGGAGCTGCTCCGTGGGGAGCACtga
- Protein Sequence
- MRIMTSTEVNGGGGTPASTTTTTTSRGGNVSVTAINCDDGGGGVSVPLDVSGSAMSAAVKHNNNNNSISNNNNNSATTGSTNSNTVNNNSTTSSSGGGSPGAIFGNVSGGIRITVPKMEESDESDTELSNIEKTAAAAAVLTNGVSMREERSASKSLPRPMSWEGELSEPEEPMLVDNENSSCSSPGGVGGGSKLVIAPIDPSPIAMIVPKREEDTETPASGPGITEPLALTATSGNGVGGGVGGVGFNLSTHGNSQVGGGTASIRNPHSGSNTGSSSSSNSPLPNRLLIKPEAGLPLINPGLAYSVSGLGNTSSNIPTSSKKGLPDVINLKYELPPGGVGGDPGGGGGTALPPGAIHSPLLVRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSIFAGGGGGGGGGGGGGGGSASFNGSPLHHSVLYKPMLDSEQQQQALKQLAAAAAAAAQEEPLYDGEHLPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGPLVNAAGGAMQAGDSPGAGPFPYGGTMRSPYVGAAGPGGGVGMGQQLKDASEGGMMMGGGPGSLGGANGGMNGVGNGTGLDIGAGTGSMQPGIPVLLQEIMDVEPLWQYNAQELARLNQPVTNVSSSAIANNPILSSAGISSDSSPDLIAELCNIADHRLYKIVKWCKSLPLFKHISIDDQICLLINSWCELLLFSCCYRSISTPGEIKISLGKSITLDQVNNSGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLSSDTSELKESEKVRSSQEKALQALQAYTLAHYPKSPAKFGELLLRIPELQRTCQVGKEMLTIKPKDGEEPSFNLLVELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00097815;
- 90% Identity
- iTF_00099056;
- 80% Identity
- iTF_00099056;