Adar000156.1
Basic Information
- Insect
- Anopheles darlingi
- Gene Symbol
- grau
- Assembly
- GCA_000211455.3
- Location
- scaffold:28710-30350[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.032 1.9 8.4 0.7 3 23 207 228 205 228 0.95 2 10 6.9 4.1e+02 1.0 0.8 6 23 237 254 237 254 0.88 3 10 4.8e-06 0.00029 20.4 0.9 1 23 260 283 260 283 0.95 4 10 0.0025 0.15 11.9 6.5 1 23 291 313 291 313 0.98 5 10 0.00023 0.014 15.1 0.0 3 23 318 339 317 339 0.96 6 10 9.3e-05 0.0055 16.4 1.1 3 23 347 367 345 367 0.96 7 10 0.0016 0.095 12.5 0.3 1 23 376 399 376 399 0.97 8 10 0.17 10 6.1 1.1 1 23 406 431 406 431 0.96 9 10 3.3e-06 0.0002 20.9 0.2 1 23 436 458 436 458 0.97 10 10 0.0052 0.31 10.9 3.1 1 23 464 487 464 487 0.98
Sequence Information
- Coding Sequence
- ATGGAAGAGTTTATGGAAAAGTGCCGCTTGTGTCTGGAACACGGTGAAGGCGTAATGGTGTCCCGTGTTGAGGAGCTACCGCCTGTGTTTACCTTCCAGCTGGATCCCGACTGTTCGCTTCCGGTGAACGTATGCCGGCAGTGCTTTAGCCAGGTTGAAGATTTCTACAGCTTCTCCAATGCGGTGCTCCAGAACCAGGAGAAGTTACGGGCATTACACGCACAACTGAAAACGGAATTCATACAAGTGGAAGAGATTAAGCTGGAATCGCCCTTCGAAACGGATGCCTTCGGTACAGCTTCCTCTATGGAGACAGAAGAAAATAAGCTCAACATAGATTCAGATACTGAAAGTCGTGAGTTGACGAGTCAGAAATCACAGTGCGACACGATGATCGTCAATACAGCAAACGATCTGGAGACGGAAGAAATTGATCAACAGGGAGACCAGAATAGCGAAGAAAATTACGATGAACCCAACGAAGAACCGGAATCCGAAGAGAACGAAAACGATGCTTTGAACAAAAGGGGTCTCAAAAGAACGCGAGAAATCAAGAGTGAGGCTGTAATCAAAATGCAGCAAGAAAACGAAATGATTGCAGACTATTTTCAGCTGGATTGTGAACAGTGCCCTCACAGAGCGGACAACTTCGTGGCTCTGAAGAAGCACTACCGTGTGCGGCATAATCGTAGCGGATATGTGCGCTGCTGTGAACGCAAACTGTTCAAACGCTGCGATCTGCTCGAGCACCAGCAGGTGCATCTCAATCCGAAGCAGTTCGCGTGCGATCTGTGCGGTAAGCAGTACCGCTCGAAGGAGTACTTACAACGGCATCGTCAGCAGGCCCACGATTCCAGCGCGGAACGCAAATTTAAATGTACCGAGTGCCATCGGAGTTTTCTGCATCGGTTTCAGCTCAATTCGCACCTTGCGCGACATGTGAAGGCCCCGTGCCCGCAGTGCGATAAAATACTTTCCAGTAAGGCGGCACTCGGTATTCACATGCAGAAGATACACAGCACCGAAGGACGCATGATATGCGATACCTGTGGGCGCGAGTTTCGTACGAAGCTGTCGTTCACGAAGCACGTGCAGCAGCACCAGGGCACGTACGTGCCGGAACAATATCGCTGTGATTACTGTAGCGCTCTGCTGGCGAGTAAAGTAAGCCTTAAGAAGCACATCCTGGTGAAGCACAAAACGACGGACGAGGAGTACGTCTGCACGAAGTGTAATAACGGAAAACGCTACCCAAACAAGTTGGCCTTCGATAGTCACAAGCGGAAGGTGCACGTCGAGAAGAAATATGCGTGTGATTTCTGTGGCCGCGGGTTTAAGGATGCGAAAAATTTGCGTGAACATCGAGCCGTCCACTCTGGTGAGGATCTGTACCGTTGCGAGCACTGCACGGTTGCCTTCAAGTGGAAGTCCAACATGTACGCACACACGAAAAAGCAGCATCCCGACGAATGGGCAGCAGCCAAACGGAAGACGGAACGCATCACGTAG
- Protein Sequence
- MEEFMEKCRLCLEHGEGVMVSRVEELPPVFTFQLDPDCSLPVNVCRQCFSQVEDFYSFSNAVLQNQEKLRALHAQLKTEFIQVEEIKLESPFETDAFGTASSMETEENKLNIDSDTESRELTSQKSQCDTMIVNTANDLETEEIDQQGDQNSEENYDEPNEEPESEENENDALNKRGLKRTREIKSEAVIKMQQENEMIADYFQLDCEQCPHRADNFVALKKHYRVRHNRSGYVRCCERKLFKRCDLLEHQQVHLNPKQFACDLCGKQYRSKEYLQRHRQQAHDSSAERKFKCTECHRSFLHRFQLNSHLARHVKAPCPQCDKILSSKAALGIHMQKIHSTEGRMICDTCGREFRTKLSFTKHVQQHQGTYVPEQYRCDYCSALLASKVSLKKHILVKHKTTDEEYVCTKCNNGKRYPNKLAFDSHKRKVHVEKKYACDFCGRGFKDAKNLREHRAVHSGEDLYRCEHCTVAFKWKSNMYAHTKKQHPDEWAAAKRKTERIT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00092999;
- 90% Identity
- -
- 80% Identity
- -