Aaqu010917.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles aquasalis
Gene Symbol
grau
Assembly
GCA_002846955.1
Location
NJHH01002162.1:28082-29731[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.044 2.8 8.1 0.6 3 23 210 231 208 231 0.95
2 10 7.8 4.9e+02 1.0 0.8 6 23 240 257 240 257 0.88
3 10 1.5e-05 0.00093 19.0 2.1 1 23 263 286 263 286 0.95
4 10 0.006 0.37 10.8 6.6 1 23 294 316 294 316 0.97
5 10 0.00026 0.017 15.1 0.0 3 23 321 342 320 342 0.96
6 10 0.00011 0.0067 16.3 1.1 3 23 350 370 348 370 0.96
7 10 0.0018 0.11 12.5 0.3 1 23 379 402 379 402 0.97
8 10 0.034 2.1 8.5 1.1 1 23 409 434 409 434 0.97
9 10 3.8e-06 0.00024 20.9 0.2 1 23 439 461 439 461 0.97
10 10 0.006 0.37 10.8 3.1 1 23 467 490 467 490 0.98

Sequence Information

Coding Sequence
ATGGAAGAGTTTTTAGAAAAGTGCCGCTTGTGTCTGGAACACGGTGAAGGGGTTTCCCGTGTGGAAGAGCTACCGCCTGTGTTCACCTTCCAGCTCGATCCCGACTGTTCGCTTCCGGTGAATGTTTGCCGGGAGTGCTTCAGCCAGGTTGAAGATTACTACAGCTTCTCCAGTGCGGTGTTACGGAACCAGGAAACATTACGGGCCTTACACGAACAGCTAAAAACGGAATTCGTAATCGTGGAAGAGATTAAAGTGGAGCCGCCCTACGAAACGGATGCTATCGGTGCAGTTTCCGCATTAGAGACAGAGGAAAATGAGCTTCATATGAATCCAGATACCGAAAGTCATGAGTTAGCGACTCAGGAATTGCATTGCGACACCACGGTCGTCATGAATATAGCAAACGATGTAGAAACAGAAGAAATTGATCAACTGGTGATGAATCAGGATCTCCAGAATAGTCAGGAAGATTACGACGAACCCAACGAAGCGCAGGAATCCGATGAGAGCGAGGCCGACACGTCGAACAAAAAGAGTCTCAGAAAAACGCGAGAGATCAAAAGTGAGGCAGCAATCAGAATGcaggaggaaaacgaaatgattgCGGAATATTTTCAGCTCGATTGTGAGCTGTGCCCTCACAGAGCGGACACCTTTGTGGCTCTGAAGAAGCACTACCGTGTGCGACACAATCGCAGCGGGTACGTGCGCTGCTGTGAGCGCAAACTGTTCAAACGCTGCGATCTGCTCGAGCATCAACAGGTGCACCTCAATCCTAATCAGTTTGCCTGCGATCTGTGCGGTAAGCAGTACCGCTCGAAGGAGTACTTacaacggcaccaccagcaggctCATGATTCCAGTGCGGAACGTAAATTTAAATGTACCGAGTGTCACCGGAGCTTTCTGCATCGATTTCAGCTCAATTCGCATCTTGTGCGGCATGTAAAGGCACCGTGCCCGCAGTGTGACAAAATACTTTCCAGCAAGGCGGCTCTCGGTATTCACATGCAGAAGATACACAGCACCGAAGGGCGCATGATATGCGATACGTGTGGTCGCGAATTTCGTACCAAGTTGTCGTTCACGAaacacgtgcagcagcaccagggtaCGTATGTGCCGGAACAATACCGCTGTGATTACTGTAGCGCACTGTTGGCGAGTAAAGTGAGCCTCAAGAAGCACATCCTGGTGAAGCACAAAACGACGGATGAGGAGTACGTCTGCACGAAGTGTAATAACGGGAAACGCTACCCAAATAAGCTAGCCTTCGAAAGCCACAAGCGGAAGGTGCACGTCGAGAAGAAGTATGCGTGTGATTTCTGTGGGCGTGGGTTTAAGGACGCGAAAAATCTGCGTGAACATCGTGCCGTCCACTCCGGTGAGGATCTGTACCGTTGCGAGCACTGTACGGTTGCTTTCAAGTGGAAATCCAACATGTACGCTCACACGAAAAAGCAGCATCCCGAAGAATGGGCAGCAGCCAAGCAGAGGGCGGCAACCATCACGTAG
Protein Sequence
MEEFLEKCRLCLEHGEGVSRVEELPPVFTFQLDPDCSLPVNVCRECFSQVEDYYSFSSAVLRNQETLRALHEQLKTEFVIVEEIKVEPPYETDAIGAVSALETEENELHMNPDTESHELATQELHCDTTVVMNIANDVETEEIDQLVMNQDLQNSQEDYDEPNEAQESDESEADTSNKKSLRKTREIKSEAAIRMQEENEMIAEYFQLDCELCPHRADTFVALKKHYRVRHNRSGYVRCCERKLFKRCDLLEHQQVHLNPNQFACDLCGKQYRSKEYLQRHHQQAHDSSAERKFKCTECHRSFLHRFQLNSHLVRHVKAPCPQCDKILSSKAALGIHMQKIHSTEGRMICDTCGREFRTKLSFTKHVQQHQGTYVPEQYRCDYCSALLASKVSLKKHILVKHKTTDEEYVCTKCNNGKRYPNKLAFESHKRKVHVEKKYACDFCGRGFKDAKNLREHRAVHSGEDLYRCEHCTVAFKWKSNMYAHTKKQHPEEWAAAKQRAATIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00098574;
90% Identity
-
80% Identity
-