Adar009539.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles darlingi
Gene Symbol
L
Assembly
GCA_000211455.3
Location
scaffold:83078-92479[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.49 29 4.7 5.8 1 23 143 165 143 165 0.98
2 16 3.9e-06 0.00023 20.7 3.7 1 23 171 193 171 193 0.99
3 16 1.2e-05 0.00069 19.2 0.3 1 23 199 221 199 221 0.98
4 16 0.45 26 4.8 0.1 2 23 407 429 406 429 0.93
5 16 0.16 9.7 6.2 0.2 1 23 769 791 769 791 0.95
6 16 2.4 1.4e+02 2.5 0.1 1 23 831 853 831 853 0.91
7 16 0.00025 0.015 15.0 0.2 1 23 907 930 907 930 0.93
8 16 0.00026 0.015 15.0 2.1 1 23 937 960 937 960 0.97
9 16 0.0036 0.21 11.4 1.8 1 23 992 1014 992 1015 0.96
10 16 0.11 6.7 6.6 0.2 1 23 1330 1354 1330 1354 0.94
11 16 0.0005 0.029 14.1 0.2 2 23 1363 1385 1362 1385 0.96
12 16 0.02 1.2 9.0 0.0 1 23 1392 1414 1392 1414 0.95
13 16 8 4.8e+02 0.8 1.4 2 20 1422 1440 1422 1443 0.91
14 16 0.015 0.86 9.5 0.2 2 23 1668 1689 1667 1689 0.94
15 16 0.0067 0.4 10.5 0.0 1 20 1699 1718 1699 1722 0.94
16 16 0.021 1.3 8.9 0.3 1 23 1730 1752 1730 1752 0.96

Sequence Information

Coding Sequence
ATGATCATCGTTATGATCGGGACAAGCGACGTGCTGTGGCAACCGGTGGTGCCCGATTTGGTGTCTCGGAGGGACGAACCGGAATCGATCGAGGGAATGTGCGTGGTGATTGGTGCGCGATCGCACAGCACGACAAGACCGTGCCCGTCGTGCCCGTGCGCCATCCATAATCGAATGCTAATGAGCCACGATGAAGGAGAAAGGAGAACAAAATTTCCCGATCCTGGCGCGCTACCGCGATCCAAAGTGCGCGATAAGAACGATCGCGACCGCACCAAGCGAACGCGCTCCCCGTTGGTCCCAGGGAACCAGTGGGGCCAAGTGTGGATCTGCGTGCCTCACCCAAAGGGGGACGAGGATCACAAAGATGATGATCATCATCGCCAGCAGCAGAAGCGACAGAAGAGCCACACGGAGCACATGCCTTTCAAGTGTGACTACTGTGCGCGGCTGTTCAAACACAAACGGTCCCGTGATCGCCACACGAAGCTACATACGGGCGACCGACGCTATCGCTGTCTGCACTGTGAGGCCGCCTTTTCGCGCAGTGATCatctgaagatccacatgaagacgcacgacaaccagaaaccgttccagtgtacgatctgCAACCGGGGCTACAACACAGCGGCCGCCCTTACGAGTCACATGCAGAACCACAAAAAGCAGCTGGCGCTCACCGGTAGCCCTAATCTCACCTACAGTCCCCGATCGACAACAAGTTCCCTCTCGAgtggtggtggtggtggtggtggGGGAAAGCGTGGCTCCAAGTTCTCGCCCTACGCCCCCAGCAACTCAAACTCCGATCCCCTGTTGCTGATGGCGGGGGGTGCTGGTGGTGGTCGATCGAGTGCGAAGCACAGCGCCGCCAAGGGTTCGAGCGCCAACGTCAACTCCATTAACCGCACACCGACACCAGCAGCCGGAGCAGAAGGAGATAGAGGAGGAAATGGGGGAAGAGGAAGCATACCAGCAGGTGGCAATCCGTCGGAACATCTCTCCTGTCTCTACTGCACCCGCACCGACTTCGGTTCGCTCGAGCAGCTCGGAATGCACGTCCAAACGATGCACGGTGGACCGCTCGGTCTGCTGGGCACCGGTGATCCATTCTTTGGCGTTTCATCGCATCTACCGCGTAGTTCGTCCGGGGGACGTCGTGCGCTAACCCCTGACGGATCACCGGCAGCACTCACCTCAAGCTATCCGCCCATCGTGTGCGAATTCTGTACGATGAAGTTCCCGACGGTGCCGTTAATGTTTGCTCACCTAAAGGCCACCCATTTGGATCGATTGACGACGACGGCGGCGGCGAGTTCGGTCGGTTGTCATCGGTTGTCACCGAACGGTGGCCGAGGTTCACCGATGGGACGCCTCTCCTCCGGTTACCAGCAAACGCTGGAGCAGCTACACTTCAACAAGAGTCTACTTAGCAGCACGTTTTCCTCCCTCTACGGTGCCAACCTTGGTGGGTCGACGCCACGTACCCCCTCCTCGGATTCGGCTGTTAAGGAAGAACGGAGGTCCACCGGTGCTAGGGATCGGAATGACGAGCgagagcaggatgcagatgaagatgaggacgatgaggaggaggaggaagacgatgacggagatgCTGAACCGGATACGAAGCGACGGCGACAGGACGAGATTCCGGCACATCGCTCACCGATCACCGGCGAGCACGATGACGCCAATCATGCCGAAACGGATCGCGAAGAGGATCAGCAAGAGAAACCGGATGAGGAAGGCCAAGACAGGCCTGCAAATGATCCAGCGATTGGTCGTATCAAGCGGGAACGCAAGGACACGGACCGCACGACACCCTCCATCAGCCATTCATCGTCAGCCCGATCTTCGCCCTGTGAATCGCACCGTTCCGGTCCAGGATCACCACCACGTGCTCCGACGGCCGACAGTCTCCGAGGGAACGCGGCCGCCGAACAGCTCACTCCTACCGATCTCAGCCAGCCGAAGATGAAGCGCCTCAAGCTGGAAGCAGAAACCGAAGAACCAGAAGCGGCAAACTGCACGCGTAAACACGATCGACCTCCGTCGAACCATCAGGAACACCGACGTCCACGGGGTGGCGGCAACAGCAAGCGAGACGGTGAAACCAGGCCGGAACAGTCCGGATCACTGCTGgcagcacactatcagcatcagcagcagcagcagcagcagcaacaacaacaacaccatattggttcgggttctggtggtggaacgtgctctgaacagcgaccacaccacctaccaccaccggcaccatcgcagtcgctaccaccacccggagcaTACCTCTGCAATCAGTGTAATGCCGCCCTGCCCGACTTTGAATCGTTCCGTACGCACCTGAAAGCACATCTCGAGCAGAGTGCCAGCGTGGCCGCGATGTCGAGTGGTCTGTCGAGTGGTTCTGGCGCAGGGACCACCCTGCTCGGCGGCACGGCCGCCGCCGGCACAGCGGCTGTTCTCTCCACGTTCCTCTGCCAACAGTGTGGGGCCACGATGGGTAGTCAGGCCGAGTACGAACAGCACACGATCGGCCATTACCTGGTGACGGCGGTCGAATATCGGTGTCCATCGGTTGTAGGAGGAGGAATGGGAACCggtggtagtggtggtggtggtgCTAGTTGTAAGACGGGAAGCTTCGCAAAGGCAGACGAGCTGCATAAGCACCTGTACGAGTCGCATCTGCAGCTACTGTACAAGTGTACCGTGTGCGGGGAGACGTTTGAGTCGAAGGTGCAGGTACAAGTCCACTTTGCCGTCAGCCATTCAGTCGAGATGAAGCTGTTCCGCTGTTCGGCCTGCAACGAAACATTCCGCACGGAGCGTGACTTCCGCCAACACATCCGCAACCGTCATCTAGCAGCCGGTGCGGTGCAATGCATGTTCTGTCGCGTCGTTTGCTCATCCGAGCTCGAAATGCACTTCCATCTTGCTTCGCACGCGAGAAAATACAAATGCCCGGCTTGTCCTGAATCGTTCCACGTAGAGTTCCTGCTCGATCGGCATCTGCAGACACACCACAGCCAGAAGGAGCTAGCCTCACCGAACCGCAGAGGAGGCGATGGAGGGACCTCCTCGAACGGACCATCGAGTATCGTCCTATCCGGAACAAATGGAATTCCTCCCGTGTCATCCTGCAGCACTGCGACGAGTGCAGCGTCATCGGTTTCCGCCACAACAACGACCGCGGCTGGACTGGAGTATCTCCAACTGCACGGTCAAATGGCTGCGATGGCGGCAGCTGCAGCGGCCGCCGCTGCTACTGGTAGCTGGCCAAGCCTCTACCAGACGGCCAACAAGTTCTACGGCAATCCGGGGCTACAAGTGGATACGCTGGGTCAGATAAAACATCCACAGCATGGCCTACTGCACGGGTTCTATGATTCGATGCTCGTAAAGGTGCCTCAGCAGCAACAGCAGCACCGAGGAGGGTTTCTATCAGACGCATCTAGTGCTCCTGGATCCACTTCTACCAGCGGTGCCAACAAGAAAAATCCATTTCTCGCTCTATCACCAAGCGCCGGAGCGTGTAAGCCAAGCGGTAACCCACTGCTAGGGCTTGGATTCGGTTCGACCAACCCGTCCCAGCGAGCACCCGGGGGAAGTGTACTGAATGGATTGTACTCTCCTGAGAGCATCGCAAATAATGCGCCTGTTAGCGCTTCCAATCCTGTTACCACGGCCGGAAGCACCAAGTTGTACTCCCCGATCACCATGATCAACCAGCGGCCATATGGTGACAATGGAGTGGTCTCTGGTACCACTACCGCTCCTGGCAGTAGTCGAGTGGACTCCGAATCACCGGTCGCAGGCAGTCAGATGGTCAGTTTTCCTATACTATCGGACCACCAGGAAAGCTCTGGTGCTTTAAAGCTGTCTACTAGCAGTGGTAGTGCCGGAAAAGGGCTTAGTAGCACCTCCATCACTACAGGCAACAGTAGTACTACCGGTGCCAACTCCTGCTACAGTTGTGGCATCTGCGAGCGAACCGATTTCAGCACGGAAAGTGAGGTTCAAACGCACCGCAAAATCGTCCATAACCTCAAAACGGGCGTCAGTTTACGCTGCGCGTACTGTAACGGTGACTTCCGGTCGAGAAATGAGCTCGAGAATCACATGAAGATCGCTCACAACACGGGCGGCGGTAAGCACAAGTGTTTGATTTGCGACGAGATCTTCCCCTCGCCGGCCGTACTGGCCGAGCACAAGCTGGCACACTGCAAGGTCGGGGCTTCGGGACGCTGTTCACACTGTAGCCTGCCACTGCCCGATGTGCACACGTTCAAGCAACACCTACCGGTACACCAAACACCAGCTAACAGCGCCACGTCAACGGCTGGTGGCCAGGGCACAGGCACGTCCAATTCGTCCACTACCGGAAGTGCTGGTGCTGCTAATGGAAGTACTGCCAGCGCTAACACTTCCTCCGCTGCCAGTTGTTCCACAGGGACGACGAGTGGTACAAATGGCAGTGTTGCAAGCGTAGAACAGGACCGATTCCCACAGCAATGCATCTGCTGCCGCCAAACACTGAATTCCGAGTTTGAGATCAGCCTGCACGCAAAATTCCACACTAAGTCAGCCGATACGAACGAGCGTACCTGTGCCCTATGCTTGGAACCGTTACCATCGCAACCGGATGCCTCGACCAAGATCTGTGACGCGTGCTTGAAGCGGCACAATTTCCCGACGAAACTCCTGTCTATGAACTTTCTCAAACCAACCGGCCAATCGCCAGGTGTTTCAGCTGCTGGTCCAACATCGACCTCTTCCGGTACCGCTGAACCTCGACCGTACAACTCTTCCTCATCATCTCACGCCGGCAATCACCCCAGTGGTGAACTGTTGCTGATGCAGCCCGGTACAGTGATGAACCGGTTGGTAGGCGATGTTTCTTGCTCAACGAATACCGAGCAACCAATGGCCGCAGGAGCAGTCGGTACCACAACAACAACCACATCACCAGCACCACCGCTTCAGTGCAATCTGTGCAAGAAGGTGCTTTCAAGCGCGCTGAAACTGCAGGAACACCTGATCGATCACACGTTCGCGGGGTGCGAGGAGCGCGGTTACGTGTGCTACCTCTGTTCAGCCGTCTTCACCTCATCGGCCGGACTACAAGCGCACCTACCGGTGGCACACTCGAACGCAACCGCCAAACCGTACGACTGTGAGCGATGCGGTGTGGCGTACTTCTTCCGGGCCGAACTCGAACACCATCTGATCGAGCACGAGGATCGCGAACGTACGGGGTTACTGTATCGGGGTGAGTGGCCAGAGCAGCGCCATGGAGAGGAACTGGGCCATCATTCTACCATCAAACAGGAACAGGACGGAGACCGGGATGAGGAAGAGGACCACCACCAGCAACAACAGCAGCAGCAGCTAAAACAGAACAGCCCCGAAGTTGGTGTGAGGCTTTGTCAGGAGCAAAGGGAGCTGGAAGACGAAGAGCAGCAGCAAGTTGAAGGCAATGAGATGCCAGGTAGAGAAGCCAATGATAGGGATGATAAGCGAGTAGAGGAGCCGGTTGATCCTGAGGAATCCGAACCCGATGATGAAGAGATTGACGACGACGATGACGACGAGGAAATCCAGAAGGAAGAGGAGGAAGAGTATATCGAGGTGGAGCATACGGTTCTGGAGGATGGGCATCACGGAAAAGAATGTTCTGGGATCGGTTCCCGCCGATCACCGATCGTTACCTCCGTTGCCGTTACAGCAGCAGAGTAG
Protein Sequence
MIIVMIGTSDVLWQPVVPDLVSRRDEPESIEGMCVVIGARSHSTTRPCPSCPCAIHNRMLMSHDEGERRTKFPDPGALPRSKVRDKNDRDRTKRTRSPLVPGNQWGQVWICVPHPKGDEDHKDDDHHRQQQKRQKSHTEHMPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGGGGGGKRGSKFSPYAPSNSNSDPLLLMAGGAGGGRSSAKHSAAKGSSANVNSINRTPTPAAGAEGDRGGNGGRGSIPAGGNPSEHLSCLYCTRTDFGSLEQLGMHVQTMHGGPLGLLGTGDPFFGVSSHLPRSSSGGRRALTPDGSPAALTSSYPPIVCEFCTMKFPTVPLMFAHLKATHLDRLTTTAAASSVGCHRLSPNGGRGSPMGRLSSGYQQTLEQLHFNKSLLSSTFSSLYGANLGGSTPRTPSSDSAVKEERRSTGARDRNDEREQDADEDEDDEEEEEDDDGDAEPDTKRRRQDEIPAHRSPITGEHDDANHAETDREEDQQEKPDEEGQDRPANDPAIGRIKRERKDTDRTTPSISHSSSARSSPCESHRSGPGSPPRAPTADSLRGNAAAEQLTPTDLSQPKMKRLKLEAETEEPEAANCTRKHDRPPSNHQEHRRPRGGGNSKRDGETRPEQSGSLLAAHYQHQQQQQQQQQQQHHIGSGSGGGTCSEQRPHHLPPPAPSQSLPPPGAYLCNQCNAALPDFESFRTHLKAHLEQSASVAAMSSGLSSGSGAGTTLLGGTAAAGTAAVLSTFLCQQCGATMGSQAEYEQHTIGHYLVTAVEYRCPSVVGGGMGTGGSGGGGASCKTGSFAKADELHKHLYESHLQLLYKCTVCGETFESKVQVQVHFAVSHSVEMKLFRCSACNETFRTERDFRQHIRNRHLAAGAVQCMFCRVVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHLQTHHSQKELASPNRRGGDGGTSSNGPSSIVLSGTNGIPPVSSCSTATSAASSVSATTTTAAGLEYLQLHGQMAAMAAAAAAAAATGSWPSLYQTANKFYGNPGLQVDTLGQIKHPQHGLLHGFYDSMLVKVPQQQQQHRGGFLSDASSAPGSTSTSGANKKNPFLALSPSAGACKPSGNPLLGLGFGSTNPSQRAPGGSVLNGLYSPESIANNAPVSASNPVTTAGSTKLYSPITMINQRPYGDNGVVSGTTTAPGSSRVDSESPVAGSQMVSFPILSDHQESSGALKLSTSSGSAGKGLSSTSITTGNSSTTGANSCYSCGICERTDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKIAHNTGGGKHKCLICDEIFPSPAVLAEHKLAHCKVGASGRCSHCSLPLPDVHTFKQHLPVHQTPANSATSTAGGQGTGTSNSSTTGSAGAANGSTASANTSSAASCSTGTTSGTNGSVASVEQDRFPQQCICCRQTLNSEFEISLHAKFHTKSADTNERTCALCLEPLPSQPDASTKICDACLKRHNFPTKLLSMNFLKPTGQSPGVSAAGPTSTSSGTAEPRPYNSSSSSHAGNHPSGELLLMQPGTVMNRLVGDVSCSTNTEQPMAAGAVGTTTTTTSPAPPLQCNLCKKVLSSALKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQAHLPVAHSNATAKPYDCERCGVAYFFRAELEHHLIEHEDRERTGLLYRGEWPEQRHGEELGHHSTIKQEQDGDRDEEEDHHQQQQQQQLKQNSPEVGVRLCQEQRELEDEEQQQVEGNEMPGREANDRDDKRVEEPVDPEESEPDDEEIDDDDDDEEIQKEEEEEYIEVEHTVLEDGHHGKECSGIGSRRSPIVTSVAVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00093025;
90% Identity
-
80% Identity
-