Aaqu004316.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles aquasalis
Gene Symbol
L
Assembly
GCA_002846955.1
Location
NJHH01002302.1:99293-116377[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.00011 0.0066 16.3 3.6 1 23 185 207 185 207 0.97
2 17 0.55 34 4.7 5.7 1 23 213 235 213 235 0.98
3 17 4.5e-06 0.00028 20.7 3.7 1 23 241 263 241 263 0.99
4 17 1.4e-05 0.00086 19.1 0.3 1 23 269 291 269 291 0.98
5 17 0.52 33 4.7 0.1 2 23 479 501 478 501 0.93
6 17 0.19 12 6.1 0.2 1 23 838 860 838 860 0.95
7 17 2.2 1.4e+02 2.8 0.1 1 23 899 921 899 921 0.91
8 17 0.0003 0.019 14.9 0.2 1 23 973 996 973 996 0.93
9 17 0.00012 0.0073 16.2 2.0 1 23 1003 1026 1003 1026 0.98
10 17 0.0042 0.26 11.3 1.8 1 23 1058 1080 1058 1081 0.96
11 17 0.13 8.4 6.6 0.2 1 23 1399 1423 1399 1423 0.94
12 17 0.00058 0.036 14.0 0.2 2 23 1432 1454 1431 1454 0.96
13 17 0.024 1.5 8.9 0.0 1 23 1461 1483 1461 1483 0.95
14 17 9.4 5.9e+02 0.8 1.4 2 20 1491 1509 1491 1512 0.91
15 17 0.066 4.2 7.5 0.1 2 23 1740 1761 1739 1761 0.95
16 17 0.0079 0.49 10.5 0.0 1 20 1771 1790 1771 1794 0.94
17 17 0.025 1.6 8.9 0.3 1 23 1802 1824 1802 1824 0.96

Sequence Information

Coding Sequence
ATGGCCATGAAGATGCTGTACCGTGGACCGAGCACACGATTGGAGACGTTGATTGAGAAAATTCAGCAAAACACGAACCTCGGTgttgtcggtggtgttggtggtggcttcagCATGATTGCACccggtgccatcggtggttTAAAAGACTTTGTAGCGCTTGGCCAAGAGCTCTACTCGCCGCACACATCGTCCAGCTTCTCGCCCTCGATGTCGGACGGTATGGCGACACCGAACTCGCTCACGAACGAAACCCAGGACGGTGGTACGCTGTTGGATTCTGTCGGTGAAAAGGTGTCCACCTTCCGCCCTGGTAGCACGCCacactcccaccaccaccatcatcatcaccatctgcaTCACCATGGACGCCACCTGCACTAtcggcgatcggtggcggGCAAGGAAGGGAAAGCCTCCCGggctcaccatcaccacaacaacaacaacaacagtagcagccacAATCACAATAATCATGGCacaggaggtggtggtggtggtggtggcaacaaccacacgaacagcaacagcaaaaacgcGGACGGCACCTATCACTGTCAGTTCTGCGACAAGACGTTCCCGCGGCTCGGATACCTCAAGAAGCATGAACAGAGCCACACGGAGCACATGCCTTTCAAGTGTGAGTACTGTGCACGGCTGTTCAAACACAAACGGTCCCGTGATCGCCACACGAAGCTGCATACGGGCGACCGGCGCTATCGCTGTTTACACTGTGAGGCCGCCTTTTCGCGCAGTGATCATCTGAAGATTCACATGAAGACGCACGACAACCAGAAACCGTTCCAGTGTACGATCTGCAACCGAGGCTACAACACAGCGGCCGCCCTGACGAGCCACATGCAGAACCACAAGAAGCAGCTGGCGCTCACCGGTAGCCCAAACCTCACCTACAGTCCCCGGTCGACTACGAGCTCTCTCtcgagcggtggtggaggtaaACGTGGCTCCAAGTTTTCGCCCTATGCCCCCAGCAACTCCAATTCCgatccactgctgctgatgggcgggggtggcggtggtggtggacgatcgAGCGCGAAACACAGCGCAGCCAAGGGTTCGAGCTCCGCTGGCAACTCCATCAACCGTACACCGACTcccggagggggaggaggaggaagaacaggagaaggtggttcgagaggaggagaaggaagcatACCAGCAGGTGGCAATCCGTCGTCCGATCATCTCTCCTGCCTGTACTGCACCCGGACCGACTTTGGTTCACTCGAGCAGCTCGGAATGCACGTCCAAACGATGCACGGTGGTCCGCTCGGTTTGCTCGGCACCGGTGATCCGTTCTTTGGCGTTTCGCAGCATCTACCACGGGCTGCGTCCGGTGGACGCCGTGCGCTAACTCCCGATGGATCACCGGCACCGCTCACCGGCACGAACTACCCACCGATCGTGTGCGAGTTCTGTACGATGAAGTTCCCGACAGTGCCGTTAATGTTTGCCCATCTGAAGGCCACCCATTTGGATCGAttaacgacgacggcggcggcggcgagcaCGATCGGTTGCCATCGGTTgtcaccgaacggtggccgtgGTTCACCGATGGGACGCCTTTCGTCCGGCTACCAGCAGTCGCTGGAGCAGCTACACTTTAACAAGAGTCTGCTTAGCAGCACCTTTTCCTCGCTCTACGGTGCCAACCTTGGTGCGTCGGCGGCACCACGCACCCCATCCTCCGATTCGGCTGTCAAGGAGGAACGGAGATCCACCGGTGCTAGAGATATCAATGATGAGCGAGAACAGGAGTCagatgaggacgaggacaaggaagatgacgatgacgatgacggggATGTTGAACCGGATACGAAGCGACGGCGACAGGACGATGTTCCGGAGCATCGCTCACCGCTACTCACCGGCGAGCACGATGACGTCGATCGTGTGGAAACGGATCGAGAGGAAGACCAAGAAGGGAAAGCGGATGAGGAAGATCGAGAAAGACCACCGGATGATCCTGCGAATGGTCATATCAAGCGGGAACGCAAAGATACCGATCGCACGACACCCTCCATCAGCCATTCATCATCTGCCCGATCTTCACCCTGTGAATCACACCGTTCCGGTCCCGGATCACCATCGCGTGCTCCGACGGCCTCCTCCGAGAGTCTCGGAAGGAACGCATCCACCGAACAGCTCACTCCGACCGATCTCAGCCAACCGAAGATGAAGCGTCTTAAGCTGGAAGCAGAAACCGACGAACCAGGAGTGGCAGAGTCCGCGCGTAAGCACGAGCAACCTCCGTCCAGCCATCAGGAACAGCGACGTGCGCGGGGTAgtggtagcaacagcagacgcGATGCTGATACCAGGACGGAACAAACGGGATCACTGCTGGCATCACAttaccagcatcaccagcagcaccatatgGGTTCCCACTCGGGGTCTAGTGAAACGTGCCACGAGCAGCGACCacatctaccaccaccggcaccatcacaacctctaccaccacccggggCCTACCTCTGCAATCAGTGTAATGCCGCCCTGCCCGATTTTGAATCGTTCCGCACGCACTTAAAAGCGCATCTCGAGCAAAGTGCCAGCGTGGCGGCAATGTCGGGTGGTCTGGcatccggcggtggtggcggaaatCCCAtccttggtggtggcccgtCCAGCACAGCGGCCGTTCTCTCGACGTTCCTCTGCCAGCAGTGTGGGGCCACGATGAGTGGTCAGGCCGAGTACGAGCAGCACACAATCGGCCATTACCTGGTAACGGCGATCGAGTATCGGTGTCCATCGGTAGGGGGTGGAGGAGCAACTAGTGGTGGCTGTACTGTGGGCCCGGGAAAAACGGGTAGCTTCGCAAAGGCCGACGAGCTGCATAAGCATCTGTACGAGTCGCACCTGCAGCTGTTGTACAAGTGTACCGTGTGTGGTGAGACGTTCGAGTCGAaggtgcaggtgcaggtgcaCTTTGCCGTTAGCCACTCGGTTGAGGCGAAGCTGTACCGCTGTTCGGCCTGTAACGAAACATTCCGCACGGAGCGTGACTTCCGGCAACACATTCGCAGCCGTCATCTAGCACCCGGAGCGATACAATGCATGTTCTGTCGCGTCGTGTGCTCGTCCGAGCTCGAGATGCACTTCCATCTTGCTTCGCACGCCAGGAAATACAAATGTCCGGCCTGTCCTGAATCGTTCCACGTAGAGTTCCTGCTCGATCGACACCTCCAGACACACCACAGTCAGAAGGAGTTAGCTTCGCCGAACCGCAgaggtggtggcgatggtgccaACTCCTCGAACGGACCATTGAGTATCGCCACATCCGGAACGAATGGCATACCACCGGCAtcatcctgcagcagcactacaACGAGTGCAGCGTCATCGGTGccatccaccaccgcaacGACCGCGGCCGGGCTGGAGTATCTTCAACTGCACGGTCAGATGGCTGCGATGgcggcagccgcagcggccgctgctgctactggtagCTGGCCAAGCCTTTACCAGACAGCCAACAAATTTTACGCCAATCCGGGACTGCAAGTAGACATGCAGATGAAACATCCACCGCATGGCCTACTCCATGGGTTCTATGATTCGATGCTTGGAAAGGCacctccgcagcagcagcagcagcagcatcgtggaGGTTTTCTAGCAGACGCATCTAGTGCTCCTGGATCCTCTTCAACCGGCAGTGCCAACAAAAAGAACCCATTTCTTGCCCTATCACCGAGTTCTGGAGCGTGCGGCAAGTCAAGCGGCAACCCACTGTTAGGGCTCGGCTTCGGCACGGCCAACCCGTCCCAGAGAGCTGCCGGGGGAAGTGTCCTGAATGGATTGTACTCTCCCGAGAGTATTGCAAACAGTGCACCAGGAAGTGCATCTAATTCTGTTACCACAGCTGGAAGCACCAAACTGTACTCCCCGATTACAATGATCCATCAGCGTCCGTATGGAGATAATGGAATGGTCACTGGCACCACTACGACCGCTGGCTCACGAGTGGATTCCGAATCACCGGTCGCAGGCGGTCAGTTGGTTAGCTTTCCTGTGCTATCGGACCACCAGGAAAGCTCCGCTGGTTTGAAGCTAACTACTGGTAATGGAAGTGCCGGAAAGGGGGTTACTAGTACCGCCAGCACAACAGGCAACAGTAGTATTACCGGTGCCAATTCCTGCTACAGCTGTGGAATCTGCGAGCGAACCGATTTCAGCACGGAAAGTGAGGTTCAAACACACCGCAAGATCGTGCATAATCTCAAGACGGGTGTCAGCTTGCGCTGCGCGTACTGTAACGGTGACTTCCGGTCAAGAAACGAGCTCGAGAATCACATGAAAATTGCGCATAACACGGGTGGCGGTAAGCACAAGTGTTTGATTTGCGATGAGATTTTCCCCTCGCCCGCCGTACTAGCCGAACATAAGCTGGCCCACTGTAAGGTCGGTGCTTCGGGACGCTGTTCGCACTGTAGCCTGCCGCTTCCCGATGTGCACACGTTCAAGCAGCACCTTCCGGTacaccaaacaccagcaaCGTCAACGGCCGGTGCACAGGGCACTGGCACGTCCAGTTCATCCGCTACCGgaggtgctgcggctgctaaTGGAAGTACTGCCTGTGCCAGCACTGCTGCCACTCCCGGTGGTTCCTCAGGGACGACAAGTAGTACAAACGTTGGTGGTTCAAGTGTGGAACAGGACCGATTCCCGCAGCAGTGCATCTGCTGCAGGCAGACACTGAATTCCGAGTTTGAGATCAGCCTGCACGCAAAATTCCACACAAAGTCGGCCGATACGAACGAGCGCACCTGTGCCCTCTGCTTAGAACCGTTACCATCGCAACCGGAGGCCTCGACCAAGATCTGCGACGCGTGCTTGAAACGACACAATTTCCCGACGAAGCTTCTATCGATGAACTTCCTCAAACCTGCCGGTCAATCGGCGGGTGTCTCAGCGACGGGCCCGCCATCGACCGCTTCCGGATCGACTGAACAACGGCCGtacacctcctcctcttcatccacCATCGGTAATCAGTCCGGCGGCGGTGAGCTGTtgcaactccagcagcagcaacagcatcatcgtaGCAACCGGTTGGTAGGCGATTTGCCCAACTCAACGAACACGGAGCAACCGGTGGCCCCAGGAACTGGCGGTGCCTCgtcaacggcaacgacgacatCACCCGCACCACCGGTTCAGTGCAATCTGTGCAAGAAGATGCTCGCAAATGCACTGAAACTGCAGGAACACCTGATCGACCATACGTTCGCGGGGTGCGAGGAACGCGGTTACGTGTGCTACCTCTGTTCGGCCGTCTTTACCTCATCGGCCGGGTTACAGGCACACCTACCGGTGGCACACTCGAACGCAACCGCCAAACCGTACGATTGtgagcggtgcggtgtggcaTACTTCTTCCGGGCCGAGCTCGAACACCATCTGATCGAGCACGAGGATCGCGAACGTACGGGATTACTGTATCGGGGTGAGTGGCCAGAGCAGCGCCAAGGAGAGGACCCGAGCCATCATTCTACCATCAAGCAGGAACAGGACAGGGACCGGAATGAGGAAGAagacgaccagcagcagcagcaggtggagCAGAACAACGCTGAAGCGGCTGTGAGGAATTGCCAGGACCAAAGTGagctagaagaagaagcgcagcAGCCAATGATTAGGGAAGCCAATGATAGGGATGATAAGCGAGCAGAGGAGAAGGTTGATTCGGACGAATCCGAAGCGGATGACGAAGAGgtttacgacgacgatgacgacgacgacgttgaaaaccagaaggaagaagaggaagagtaTATCGAGGTAGAGCATACGGTGCTGGAGGAAGGGCATCACGGAAAGGAACGATCCAGGATCGGTGCCcgccgatcaccgatcgtttCCTCGGTTGCCGTTACAGCAGCAGAATAG
Protein Sequence
MAMKMLYRGPSTRLETLIEKIQQNTNLGVVGGVGGGFSMIAPGAIGGLKDFVALGQELYSPHTSSSFSPSMSDGMATPNSLTNETQDGGTLLDSVGEKVSTFRPGSTPHSHHHHHHHHLHHHGRHLHYRRSVAGKEGKASRAHHHHNNNNNSSSHNHNNHGTGGGGGGGGNNHTNSNSKNADGTYHCQFCDKTFPRLGYLKKHEQSHTEHMPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCLHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQLALTGSPNLTYSPRSTTSSLSSGGGGKRGSKFSPYAPSNSNSDPLLLMGGGGGGGGRSSAKHSAAKGSSSAGNSINRTPTPGGGGGGRTGEGGSRGGEGSIPAGGNPSSDHLSCLYCTRTDFGSLEQLGMHVQTMHGGPLGLLGTGDPFFGVSQHLPRAASGGRRALTPDGSPAPLTGTNYPPIVCEFCTMKFPTVPLMFAHLKATHLDRLTTTAAAASTIGCHRLSPNGGRGSPMGRLSSGYQQSLEQLHFNKSLLSSTFSSLYGANLGASAAPRTPSSDSAVKEERRSTGARDINDEREQESDEDEDKEDDDDDDGDVEPDTKRRRQDDVPEHRSPLLTGEHDDVDRVETDREEDQEGKADEEDRERPPDDPANGHIKRERKDTDRTTPSISHSSSARSSPCESHRSGPGSPSRAPTASSESLGRNASTEQLTPTDLSQPKMKRLKLEAETDEPGVAESARKHEQPPSSHQEQRRARGSGSNSRRDADTRTEQTGSLLASHYQHHQQHHMGSHSGSSETCHEQRPHLPPPAPSQPLPPPGAYLCNQCNAALPDFESFRTHLKAHLEQSASVAAMSGGLASGGGGGNPILGGGPSSTAAVLSTFLCQQCGATMSGQAEYEQHTIGHYLVTAIEYRCPSVGGGGATSGGCTVGPGKTGSFAKADELHKHLYESHLQLLYKCTVCGETFESKVQVQVHFAVSHSVEAKLYRCSACNETFRTERDFRQHIRSRHLAPGAIQCMFCRVVCSSELEMHFHLASHARKYKCPACPESFHVEFLLDRHLQTHHSQKELASPNRRGGGDGANSSNGPLSIATSGTNGIPPASSCSSTTTSAASSVPSTTATTAAGLEYLQLHGQMAAMAAAAAAAAATGSWPSLYQTANKFYANPGLQVDMQMKHPPHGLLHGFYDSMLGKAPPQQQQQQHRGGFLADASSAPGSSSTGSANKKNPFLALSPSSGACGKSSGNPLLGLGFGTANPSQRAAGGSVLNGLYSPESIANSAPGSASNSVTTAGSTKLYSPITMIHQRPYGDNGMVTGTTTTAGSRVDSESPVAGGQLVSFPVLSDHQESSAGLKLTTGNGSAGKGVTSTASTTGNSSITGANSCYSCGICERTDFSTESEVQTHRKIVHNLKTGVSLRCAYCNGDFRSRNELENHMKIAHNTGGGKHKCLICDEIFPSPAVLAEHKLAHCKVGASGRCSHCSLPLPDVHTFKQHLPVHQTPATSTAGAQGTGTSSSSATGGAAAANGSTACASTAATPGGSSGTTSSTNVGGSSVEQDRFPQQCICCRQTLNSEFEISLHAKFHTKSADTNERTCALCLEPLPSQPEASTKICDACLKRHNFPTKLLSMNFLKPAGQSAGVSATGPPSTASGSTEQRPYTSSSSSTIGNQSGGGELLQLQQQQQHHRSNRLVGDLPNSTNTEQPVAPGTGGASSTATTTSPAPPVQCNLCKKMLANALKLQEHLIDHTFAGCEERGYVCYLCSAVFTSSAGLQAHLPVAHSNATAKPYDCERCGVAYFFRAELEHHLIEHEDRERTGLLYRGEWPEQRQGEDPSHHSTIKQEQDRDRNEEEDDQQQQQVEQNNAEAAVRNCQDQSELEEEAQQPMIREANDRDDKRAEEKVDSDESEADDEEVYDDDDDDDVENQKEEEEEYIEVEHTVLEEGHHGKERSRIGARRSPIVSSVAVTAAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00098552;
90% Identity
-
80% Identity
-