Basic Information

Insect: Anopheles darlingi
Gene Symbol: -
Assembly: GCA_000211455.3
Location: scaffold:770115-774079[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0058 0.34 10.7 1.8 2 23 286 308 286 308 0.96

2 11 3.3e-05 0.0019 17.8 2.0 1 23 313 335 313 335 0.98

3 11 0.00014 0.0082 15.8 2.3 1 23 341 363 341 363 0.96

4 11 3.5e-05 0.0021 17.7 2.8 1 23 369 391 369 391 0.98

5 11 1.6e-05 0.00093 18.8 1.3 1 23 397 419 397 419 0.97

6 11 6.7e-09 3.9e-07 29.4 0.9 1 23 425 447 425 447 0.99

7 11 5.4e-07 3.2e-05 23.4 0.2 1 23 453 475 453 475 0.99

8 11 0.00011 0.0062 16.2 0.0 3 23 486 506 484 506 0.97

9 11 0.00097 0.057 13.2 3.2 3 23 514 534 512 534 0.98

10 11 3.1e-05 0.0019 17.8 1.4 1 23 540 562 540 562 0.93

11 11 6.2e-05 0.0037 16.9 4.2 1 23 568 590 568 590 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0058	0.34	10.7	1.8	2	23	286	308	286	308	0.96
2	11	3.3e-05	0.0019	17.8	2.0	1	23	313	335	313	335	0.98
3	11	0.00014	0.0082	15.8	2.3	1	23	341	363	341	363	0.96
4	11	3.5e-05	0.0021	17.7	2.8	1	23	369	391	369	391	0.98
5	11	1.6e-05	0.00093	18.8	1.3	1	23	397	419	397	419	0.97
6	11	6.7e-09	3.9e-07	29.4	0.9	1	23	425	447	425	447	0.99
7	11	5.4e-07	3.2e-05	23.4	0.2	1	23	453	475	453	475	0.99
8	11	0.00011	0.0062	16.2	0.0	3	23	486	506	484	506	0.97
9	11	0.00097	0.057	13.2	3.2	3	23	514	534	512	534	0.98
10	11	3.1e-05	0.0019	17.8	1.4	1	23	540	562	540	562	0.93
11	11	6.2e-05	0.0037	16.9	4.2	1	23	568	590	568	590	0.99

Sequence Information

Coding Sequence: ATGAGTTGCACGAGCATTTCGATAACCGAATCCGACGGACTGCCGTGCCATATCTGTCTCGATTGCTGCTCACAGGTTGAGCGAAGCTGTAATTTCCGGCATATGAGCGAACAGTCCGATGCCACGATCCGATCGTTAATTGAGCAATCCGTCGTCATCAAACAGGACAGCGAGACCAAGTACGAGGTGCTCAATGTAGTGCTGACCGATTCCAATGGTAACACTGAAACCTCAGCCGTGGTGGTTCCGATCGAAGAGTTTCGCTTTCAACTGGTCAACAGCAGCGAAGTGTCTGTAGAGCAATACCGCGACAAGCCGACCGGCACAGTTCAGGCGCAGGAAGCTCCCGAGATGGCTGAACCAGAAGAACAGATCACGCCAACAGTGAAATCAACGACGAAAGAATATGAAGATCTCTACTCGATCACGGTCAATCCAAGTGAGCTGCTGAATGAATTGTCGCAAACACCGCCTCCTGAGAGACCTCCAAAGGAAACTGCGGTAGCACAAGGCGAGTCAGCCTCGAAGGAATCAACCATTCTGAAGAACCTCAAAAAGGAGCTGTCGGAATTCATAGGCAGCAACTGCACGATCGTACCGAAGGAAACCGAGATCGTCGATGAGAATGAGGATGACGAAATGATTCACGTGAACTATCTCAAAGATGCCTTAACGGAGGAATACATTCAAATCATGGAAACCCAATTGGCATCCTCCGTGCCCAACGATGCCCCAGGAACGGCCCAGGAACAGCTGGAACAGGAGCACCTGAACAACCTGATTAGCGCCTCGATGGAAGCCGAAGGATCGCGTCCCGTGGTGCATTCTGCCGATACCGAGGAGCAAGGCACGCGATACTGTAAGCTATGCGATGTCCATTTCAGCGAACGAAGACTGTACCGGGCGCACGTGAAAAGAATACATTCCGAAAAACGTTATGAGTGCACCAGCTGCTCTCGGAAGTTTACGGAAAAATCGATGCTCAATAATCACCTTTTGCGAcacacgggtgaaaaaactcacgcgtgcagtgagtgtaatgcaaagttttacgaaagaaataccctaaacatgcacatgcgaacacattccggacagcgaccgtacgcctgtgagcattgcgacaaacggttcactaagagaagcatactaacgacgcacctgaaagtgcacaaggaacctcggccacacgtgtgcaccgtatgccagaagggattcaaactctcctggcagctgaaagctcacacgcgcattcacacgaacgaaaaaccattccagtgtccacagtgccagaagcggttcaatcagaacggcaaccttatcgttcacatgcgtacgcattctggcgaaaaaccgtaccagtgtaaagactgtgataaagcctttcccagcAAAGGGGAACTGGGTGGCCACATGCGACAGCACACGGGAGAGAAGAAGACGAAAAAGATCGCTTGTTCCCTGTGTCCGAAACTGTTTGCCGCCAACTAcgatctcgcgattcacatgcgcacccataccaaggagcgaccgtttggatgtaccgtttgcggaaaaaggttcctgatgcacgtgcacctgacggttcatatgcgatcgcacaccggcgagaaaccgtttgcctgtacgctgtgcgaaaaggCATTCACAACACGCTATCAACTGAAAACACACAATTATGTCCACACTGGTGAGAAGAATTACGAGTGCGATGTGTGTCATCGAAAGTTCAGCAGCGCCACTAATCGGAATACTCATCGAAAGACGCATGATCGGACAATTTCCTGA
Protein Sequence: MSCTSISITESDGLPCHICLDCCSQVERSCNFRHMSEQSDATIRSLIEQSVVIKQDSETKYEVLNVVLTDSNGNTETSAVVVPIEEFRFQLVNSSEVSVEQYRDKPTGTVQAQEAPEMAEPEEQITPTVKSTTKEYEDLYSITVNPSELLNELSQTPPPERPPKETAVAQGESASKESTILKNLKKELSEFIGSNCTIVPKETEIVDENEDDEMIHVNYLKDALTEEYIQIMETQLASSVPNDAPGTAQEQLEQEHLNNLISASMEAEGSRPVVHSADTEEQGTRYCKLCDVHFSERRLYRAHVKRIHSEKRYECTSCSRKFTEKSMLNNHLLRHTGEKTHACSECNAKFYERNTLNMHMRTHSGQRPYACEHCDKRFTKRSILTTHLKVHKEPRPHVCTVCQKGFKLSWQLKAHTRIHTNEKPFQCPQCQKRFNQNGNLIVHMRTHSGEKPYQCKDCDKAFPSKGELGGHMRQHTGEKKTKKIACSLCPKLFAANYDLAIHMRTHTKERPFGCTVCGKRFLMHVHLTVHMRSHTGEKPFACTLCEKAFTTRYQLKTHNYVHTGEKNYECDVCHRKFSSATNRNTHRKTHDRTIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00092305; iTF_00092949;
90% Identity: iTF_00092305; iTF_00092949;
80% Identity: -