Adar008970.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles darlingi
Gene Symbol
-
Assembly
GCA_000211455.3
Location
scaffold:29765-34412[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 2e-05 0.0012 18.5 0.7 2 23 411 432 410 432 0.95
2 12 0.0087 0.52 10.2 1.9 1 23 441 463 441 463 0.98
3 12 1.1e-06 6.3e-05 22.5 0.3 2 23 471 492 470 492 0.97
4 12 1.8e-06 0.00011 21.7 0.9 1 23 498 520 498 520 0.99
5 12 7.4e-05 0.0044 16.7 0.9 1 23 527 549 527 549 0.98
6 12 0.00013 0.0074 15.9 1.5 1 23 555 577 555 577 0.97
7 12 2.9e-06 0.00017 21.1 0.2 1 23 583 605 583 605 0.98
8 12 5.8e-06 0.00034 20.2 1.1 1 23 611 634 611 634 0.96
9 12 2.6e-05 0.0016 18.1 2.3 1 23 640 663 640 663 0.97
10 12 3.3e-05 0.002 17.8 3.2 1 23 669 691 669 691 0.99
11 12 2.5e-05 0.0015 18.1 1.4 1 23 697 719 697 719 0.97
12 12 0.00052 0.031 14.0 1.0 1 23 725 749 725 749 0.92

Sequence Information

Coding Sequence
ATGAGACACGACGATCCGGTTTCGGCCGAGCTGGAACAGCCGGAACAACCGTTTCACTTCCCATACTGTTACATCTGCAACACGCCCGACTTACAGACCGAAACGGGCAACCTCTGCATGCTGTTCCAAGCGGAACAAAATGGATATTCGGCGTCGAAGACGCTGACCGAAATCCTGCAGATCGACGTCACACCGGAGCTGTGCCATTCGCAGCTCATCTGCATCAACTGCAACCTGCTCTGCGTCGAGTATCAACAGTTGCTGGAACGGGTGGAGACCATAAGAATCCAGATGACGGTGGCCTATAATCAAACCGTCATGAAACTGGCGGGTCTTACGGAGAAAGTCCTGAAGGACACACCCGTTACCGATGAGAACCTGGAGCAGGCACTGCAAAGCTTCGAAAAAGGATTTATGTCGATCGATGAAGTATTCCAAATGGAAGGTCTCGTTGCTGATTCCATCATCGAAGATCCGTCTTCGGACCACATTGAAGGTGTGCTGCCAAAGCTAACGCTTGATTGGCATGCGGCCACTACGGACCAACCCATCGATTCGTCCATTCTGTTAAGTTCAGCTACAATGGCCGATGAGCAACCGCAGCTCGATGAACAACCGCCGCAAGCTATCGATCCAGAGCCGGAGCAAACCCTTACCACCGATCAAAACGTTGTTTCGTCACATTTGGGGCCGGATGAAGCGACCCTAATAGCACCGGACACCGGGGCTCCTGCTGACTGTGATATTAGCAACGACGATAAACTCCATTCGCTGATTGCGGATAGAATCGTCGAAGTGAAGGCAGATGATGGTACGGTTATGTATTGTGTCTACGAGAATGTAATAGAATCGTACAGTGACCAAGAAGAAGCCCCACCGGAAGtgatgatggacggcaatgacggtgttgatgctgtgactaacgatgacgatgatgatgatgatgcggttgaatacgatgaAGTGATAGTAGAGAGTTCAGAACCTGCTGTGACGGAACATACGCCCGGGGTGCCACCACCAACGTCGTCCTTTTTAGATGAAATTCAAGAGCAACCGGCACCAACCGGAAACAACGAGACAAACGAACTTGCCATCACGCAACCGCTCTTTTTTAAGGTGGAAGACCTGTACTACTGTACGGCCTGCAGCACGCAGGGCAAGATGAAAGGGGACCACGTGAAGGGCATCGCCCATCACCTGAAGGTGGAACACGGCGAGAAGATACTCGTGTGCGAACGGTGCGATGAGGTGTTCCGAAGCCGGTCGACCTACAACAAGCACATGGATCAGCATATGGCCGACGACTGTGGAGGGGATTTTAGCTGTGATATCTGCGCCACCAAGTTCTACTCTGTGCGAGCGTTACGCATCCATCACAAAAACCACGTACCGGCCTCCAAGCTGTGGTCCTGCGATCTCTGCGACAAGAAGTACGTCACGAAGAGCCTcctggaggtgcacatgaacacgcacacgggggagcgaccgtaccagtgcaccgtttgctccaaggatttctcctccaagtacgtgctggcagtgcacatgaagacccacagcgaacgTGAACGCAACTTTGTCTGCACGGTGTGTAATGCTTCGTTCTTCAAGCGCAACAATCTGATGCAGCACGAGCGTATCCATCTCGGTTTGAAGGAGTACATGTGTCGCGATTGCGGCAAACAGTTCCTATCGCAGCATAATCTCAATGTGCACCGTATCATCCATGCTGGCCATAAACCGTTCTCCTGTCGGACGTGCGGTAAAGCGTTCGCCCGGAAAGCCGAATTGATCGATCATGAGCGGATACACACGGGTGAGAAACCGTTCGCCTGCGATATCTGTGATGCCCGTTTTGCACAGCGGTCCAACCTGCACTCGCACCGGAGGGTTACGCATATGAATGATAAGCGGTTCAAGTGTGAGATATGCGGTGCTTGCTTCAAGCGACGCCGATTGCTGGTGTATCACGAGCGATCGATGCACACTGGCGAGCGACCGTACAAGTGCGATCAGTGCAAAGCTACCTTCGCGTATCCGGAGCACTTCCAGAAGCACAAACGCATCCATAACGGCACAAAACCATTCTCCTGCGAGGTCTGTAACAAATCGTTCAACACCCGGGACAACCGAAATGCGCACCGGTACGTGCACAGTGACAAGAAACCGTTCGAGTGCGTCACTTGCGGTGCCGGGTTCATGCGCAAGTCGCACTTGTACGGACATATGCAAAAGTTCGGTCACCTAAACGATACCATCATCGTCAACCAACCACACATCAAGCCAAACGATACGCTGGACTTTACCCACGAATCCATCACCTTCGCAACCGCCGATGCACCTGCAGGTGAAGATACGGGTGAACCCACGGAACCGGGAGCGGCGGTGGACAGCGGCAGCGAAAGTGTGGCCGGCCATCACTCGCGGCAAATCATCATCGAAGGGGAAGAGGAGACGGAAGAAACAATCGATGACATCATCGAAACGGATGAGTACTACATCGAGCAGGAGGACGATGAAGTGGAAGGTATACTCGAGGATACAAGCAACAGTACTTCGGTTCCCATCGCTGATCTACAAATGGTGCAAAGCGGCATTGACGATGACAGTGCCATCGAGTAG
Protein Sequence
MRHDDPVSAELEQPEQPFHFPYCYICNTPDLQTETGNLCMLFQAEQNGYSASKTLTEILQIDVTPELCHSQLICINCNLLCVEYQQLLERVETIRIQMTVAYNQTVMKLAGLTEKVLKDTPVTDENLEQALQSFEKGFMSIDEVFQMEGLVADSIIEDPSSDHIEGVLPKLTLDWHAATTDQPIDSSILLSSATMADEQPQLDEQPPQAIDPEPEQTLTTDQNVVSSHLGPDEATLIAPDTGAPADCDISNDDKLHSLIADRIVEVKADDGTVMYCVYENVIESYSDQEEAPPEVMMDGNDGVDAVTNDDDDDDDAVEYDEVIVESSEPAVTEHTPGVPPPTSSFLDEIQEQPAPTGNNETNELAITQPLFFKVEDLYYCTACSTQGKMKGDHVKGIAHHLKVEHGEKILVCERCDEVFRSRSTYNKHMDQHMADDCGGDFSCDICATKFYSVRALRIHHKNHVPASKLWSCDLCDKKYVTKSLLEVHMNTHTGERPYQCTVCSKDFSSKYVLAVHMKTHSERERNFVCTVCNASFFKRNNLMQHERIHLGLKEYMCRDCGKQFLSQHNLNVHRIIHAGHKPFSCRTCGKAFARKAELIDHERIHTGEKPFACDICDARFAQRSNLHSHRRVTHMNDKRFKCEICGACFKRRRLLVYHERSMHTGERPYKCDQCKATFAYPEHFQKHKRIHNGTKPFSCEVCNKSFNTRDNRNAHRYVHSDKKPFECVTCGAGFMRKSHLYGHMQKFGHLNDTIIVNQPHIKPNDTLDFTHESITFATADAPAGEDTGEPTEPGAAVDSGSESVAGHHSRQIIIEGEEETEETIDDIIETDEYYIEQEDDEVEGILEDTSNSTSVPIADLQMVQSGIDDDSAIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00092945;
90% Identity
-
80% Identity
-