Adar000920.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles darlingi
Gene Symbol
su(Hw)
Assembly
GCA_000211455.3
Location
scaffold:117450-120342[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.022 1.3 8.9 0.6 3 20 77 94 75 96 0.91
2 13 0.00079 0.047 13.4 1.7 2 23 152 174 151 174 0.95
3 13 0.018 1.1 9.1 2.3 1 23 180 202 180 202 0.98
4 13 0.00095 0.056 13.2 2.1 1 21 208 228 208 229 0.91
5 13 1.5e-07 8.9e-06 25.1 0.1 2 23 241 262 240 262 0.96
6 13 3.3e-08 1.9e-06 27.2 1.1 1 23 272 294 272 294 0.99
7 13 5.9e-05 0.0035 17.0 0.3 1 23 300 322 300 322 0.98
8 13 3e-05 0.0018 17.9 0.7 1 23 328 350 328 350 0.99
9 13 1.4e-06 8.1e-05 22.1 2.5 1 23 356 378 356 378 0.97
10 13 3.6e-06 0.00021 20.8 0.5 1 23 384 407 384 407 0.95
11 13 1.5e-05 0.00086 18.9 0.9 1 23 413 435 413 435 0.96
12 13 8.5e-07 5.1e-05 22.8 0.3 1 23 441 463 441 463 0.99
13 13 0.00081 0.048 13.4 3.4 2 23 470 492 469 492 0.95

Sequence Information

Coding Sequence
ATGGCCCTCCGTGCTTCTCGAGCTACGGCTTCTAAGATGAAGGAGAAAAAGGAGGAAATTCTGGTGAAGGTGCGGATGAACGGAGAAAACGATATCGATGTAGTGCCCATGGAGAAGGAGATCGACTCGAACTCCGAGGAGGCTCTCTCGGATAGGCTCGATTCGGAACCGGAGCTGGTAACGACGTCCGACGGTCGGATGAGGTTGGAATTGAAGCGCAGCAGGTGCTGTGGTCGATGCAAGACGCCCTTTAAAACAGCAGAGGCCCTGAAGGAACACAAAGCGGTATGCACGGGAGTACTGGACGAAATACAGGACGTGATCCAGAAGGAGCGCAAAGCCGCCAAATATGCTAACCCGAGCGAGGAGTTCCGCAAGTACTGCAATCCGAACCCAGAAAATCCGTGCTACTGCTGTGGCGAGGACGTAAGCACGGCTCACGTCGGGCATATCCGGTGTCGGTTCTGCCCCAAATCCTTTAAGGCGTACGAGTATCTCCATCGTCACATCAGCTCGATCCACGCCACATCGGAGACGTACGCTTGCGCCAACTGTAATGCCAAGTGTTGCTCCCAGAGTGTCCTGGATGAGCATATAAAGACGCACAACGAGGGTAAACCGTTCTCCTGCATCACCTGCGGTAAGGACTTTACGCGTCGCTATCATCTCGATCGGCACCTGAAGTTCTCGAACTGTGGCACCGAGCGAAAGGAAACGTTGCCGTGTGACGTGTGCGGTAAGGTTTTCACACGCATCGACAATTTGCGCGAGCACTTGCGAAGTCATATGGGCCAGAGTGTGCGCAAGCGGGACTACCAGTGTCCACATTGTCCGAAATCGTTCTACGGGTCGTcgctgctcaacatacacatccggacgcacacgggtgagaaaccgttcccgtgtgatctctgtccgagctcgttcccctcgaccggggcgctccggaagcatcgacgcaagcacaccggagaacgaccgtaccggtgtgacgagtgttcggcaacctttgcggccagggaaacgctcaatcggcatcgcaagacgcatacgggcgataagcggcatgtctgcacggaatgtggcaagcgtttcatccaagcaacccagcttcgcacgcatatgttcaagcacaccggAATGAGTGACTTCAAATGTGGCCAGTGTGATAAGATGTTTGTGCGTAAAAACCAGCTAACCGAGCATGTCATGCTCGTGCACCAGGGCAAGGAACCATTTCAATGCGACTACTGCGACAGGGAATTTTTGCGCAAGGAGGATTTACAGCGCCACATGGTTCAACATACTGGAGAGAGAAATTACGAATGCCCAACTTGTTCGAAAACATTCGCGGTAAAAACGGCTCTTTCGGTACACATGAAAACGCACATCATACAGAAACCGGTCAAATGCAGAATCTGCCATGGATCCTTCATACGAAACGATTGCCTCGTGCGCCACATGAAAGCGAAGCACCGTGAGGATTGTCAAGAGTTACTTGAGGAATCAGACGAGTCTCCGGTCGCTGGAGTAGCCAATGAAGCAACGGTTGAGATCAACGGTGAAGTCTATCAGATCACGTCGATGGATGAGCAGGAGGCCGAACCGATACTTCATGATGAGGTGGAGGTTATGGAGCTGGACGTTGTTGCTGAGGAATCGGTCGTAACAACGGCAGACGCTACGATTATAGCGACAGCGGATATCGAAGATTCCAACAAAGAGTGTACCGGTACGATGCTCAAAGCAGTTCCCGAGTTCGTTAATGTTAAGCAGGAGTCTACCGTGGTTACGGCGAAAAAGAAAAGAACGGAATTGCAAGTAAGATCAAATCCTAAAACGAAAGCAGAGATCCCACCAACAACTTCTTTGCCCGCTGCAACTAAGATTCGCAATGTACGAACAACCACAGTAAAAGTTGTTCAGAAAACGGCTGCATCTTCATCTTCGGTTATCAAGCCCGAGAAGGTTGAACCAGTTCGCGAACCGAATTTGACGAAAGCACGAGCTCTGAAATCTCGAGCAGTACCGGCAAAACGATCACGGCCGGATGATGATGGCATACCCATCTTTCTTAGCGATGCAATGTTGATGGAGAAGATTTCGGAACTACTGGAAATGTTGATTGGCGAAGAAATGTTGAAGGAGTTCGGTTGGCCAAAAGCGCCCGTCGATGAGGTGCTGGTTCGTGTGATTTCTCGTTGTGGTCAACAGCCGGCTAAAGGCGAGGAAGTGGGTGATCATACGACGCGTATGCGTGAGAACACCAAAATCCTGTTCTCCGTGACGATGGATGATGGTGACGTGAAGGCACTGCTTAACAACCATACAGTGGACGAGGTCATCATGCATGTCCTAAAAAGCAAATAG
Protein Sequence
MALRASRATASKMKEKKEEILVKVRMNGENDIDVVPMEKEIDSNSEEALSDRLDSEPELVTTSDGRMRLELKRSRCCGRCKTPFKTAEALKEHKAVCTGVLDEIQDVIQKERKAAKYANPSEEFRKYCNPNPENPCYCCGEDVSTAHVGHIRCRFCPKSFKAYEYLHRHISSIHATSETYACANCNAKCCSQSVLDEHIKTHNEGKPFSCITCGKDFTRRYHLDRHLKFSNCGTERKETLPCDVCGKVFTRIDNLREHLRSHMGQSVRKRDYQCPHCPKSFYGSSLLNIHIRTHTGEKPFPCDLCPSSFPSTGALRKHRRKHTGERPYRCDECSATFAARETLNRHRKTHTGDKRHVCTECGKRFIQATQLRTHMFKHTGMSDFKCGQCDKMFVRKNQLTEHVMLVHQGKEPFQCDYCDREFLRKEDLQRHMVQHTGERNYECPTCSKTFAVKTALSVHMKTHIIQKPVKCRICHGSFIRNDCLVRHMKAKHREDCQELLEESDESPVAGVANEATVEINGEVYQITSMDEQEAEPILHDEVEVMELDVVAEESVVTTADATIIATADIEDSNKECTGTMLKAVPEFVNVKQESTVVTAKKKRTELQVRSNPKTKAEIPPTTSLPAATKIRNVRTTTVKVVQKTAASSSSVIKPEKVEPVREPNLTKARALKSRAVPAKRSRPDDDGIPIFLSDAMLMEKISELLEMLIGEEMLKEFGWPKAPVDEVLVRVISRCGQQPAKGEEVGDHTTRMRENTKILFSVTMDDGDVKALLNNHTVDEVIMHVLKSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00092291; iTF_00092942;
90% Identity
-
80% Identity
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