Aaqu001994.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles aquasalis
Gene Symbol
su(Hw)
Assembly
GCA_002846955.1
Location
NJHH01002377.1:91198-94108[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.21 13 6.0 1.3 3 20 78 95 76 97 0.88
2 13 0.00034 0.021 14.7 0.4 2 23 153 175 152 175 0.96
3 13 0.068 4.3 7.5 2.2 1 23 181 203 181 203 0.97
4 13 0.00026 0.016 15.1 1.0 6 21 214 229 209 230 0.88
5 13 6.7e-08 4.2e-06 26.4 0.1 2 23 242 263 241 263 0.97
6 13 3.7e-08 2.3e-06 27.2 1.1 1 23 273 295 273 295 0.99
7 13 6.7e-05 0.0042 17.0 0.3 1 23 301 323 301 323 0.98
8 13 3.4e-05 0.0021 17.9 0.7 1 23 329 351 329 351 0.99
9 13 5.8e-07 3.6e-05 23.5 1.1 1 23 357 379 357 379 0.97
10 13 0.0012 0.074 13.1 0.5 1 23 385 408 385 408 0.96
11 13 0.00034 0.021 14.8 0.8 2 23 415 436 414 436 0.95
12 13 7.5e-06 0.00047 20.0 0.5 1 23 442 464 442 464 0.99
13 13 7.9e-05 0.005 16.7 0.8 2 23 471 493 470 493 0.95

Sequence Information

Coding Sequence
ATGGCCACCCGTGCTTCTCTACGTGCGGCTCCtaagaaaaaggaggaaatcCTGGTGAAGATGCGCATTAATGAGGAAAATGATATCGACGTGGTGCCCGTGGTGAAAGATATGtacgactccgactccgactcgGAAGAGGGTAACCCCTCGGATCAACTCGATTTCGAACCGGAGCTGGTGGAAACGTCCGATGGTCGGATGATGCTGGAATTAAAGCGCAACAAGTGCTGTGTTCGATGCAAGAAGCCCTTCACAACGTTAGAGGCGCAGAAGGCACACAGATCGGAGTGCACGGGTGTGGTGGATGAAATGCACGACGTGATCCAAAAGGAGCGTAAAGCCGCCAAATACGCTAACCCGGGCGAGGAGTTCCACAAGTACTGCAATCCGAACCCGGAAAATccgtgctactgctgtggtGAGGATGTAAGCACGGCTCACGTCGGCCACATCCGGTGTCGGCTCTGTCCCAAATCCTTCAAGGCGTACGAGTATCTGGATCGTCACATCAAGTCGATCCACGCCGAATCGGAGGCGTATGCGTGCGCCAACTGTAATGCCAAGTGCTGCTCCCAGAGTGTCCTGGATGAGCACGTAAAGACGCACAGCGAGGGTAAACCGTTCTCCTGCATCGCCTGCGGTAAGGACTTTACGCGTCGCTACCATCTCGAACGGCACATCAAGTTTTCGAACTGTGGCACCGAGCGGAAAGAAACGTTGCCGTGTGACGTGTGCGGTAAGGTGTTCACACGTGTCGACAATTTGCGCGAACATTTGCGCACTCACATGGGCCAGAGTGTGCGCAAGCGTGACTACCAGTGCCCGCACTGCCCGAAATCGTTCTACGGATCGTCGCTGCTCAACATACACATCCGGACGCACACGGGCGAAAAACCGTTCCCGTGCGATCTCTGCCCGAGCTCGTTTCCCTCGACCGGAGCACTGCGGAAGCATCGGCGCAAGCACACCGGGGAAAGGCCGTACCGCTGTGATGAGTGTTCCGCAACCTTTGCGGCCAGGGAAACGCTCAATCGCCATCGCAAGACGCATACGGGCGATAAGCGTCATGTCTGCCCGGAGTGTGGCAAGCGATTCATCCAAGCAACCCAGCTCCGAACGCACATCTACAAGCACACCGGGAAGAGTGACTTCAAATGCGGCCAGTGTGATATGATGTTCTTGCGTAGAAACCAGCTCACCGAACACATCCAGCTCGTGCATCAGGGCAAGGAACCCCTTAAATGCGACTACTGTGACAAAGAGTATTTGCGCAAGGAGGACTTGCAGCGCCACAGGGCTCAGCACACTGGAGAGAAGAATTACCAGTGCCCAACTTGCTTGAAAACATTTGCGCTGAAAACGGCCCTATCGATACATATGAAAACGCACCTCCAGCCGGAACCGGTCACATGCACAATCTGTAACGGATCCTTCATTCGACCCGATTGCCTCGTGCGCCACATGAAAGCGAAGCACCGTGTGGATTGCAAAGAGCTCCTTGAGCAACAAGATGAGTCTCCGGTCGCTAGTCCGGAAGTAGCGAATGGAGCAATGGTTGAGATCAACGGTGAGGTCTATCAAATCACGTCGATGGATGAGCAGGTGGCCGAACCGATGCTTCCTGAAGGTGTAGAGTTCATGGAGTTGGACATTGTTGCAGAGGAATCGGTCgaaacaacagaagcagctaCGATTATAACAGGCGATGACGTTGATAGTGACCAAGAGTACGCCGATGAGATTCTCGAAGCTGTTCCCGAGTTGGTTAATGTTAAGCAGGAGCCTGTCGTAGTTGAGGTGAAAAAGAATCGAACGGAATTGCTAACAAAATCAATTCCGAAAATGAAAGCAGAGAACACATCAACTACTTCCCCGACCGTTGCAAATGAGATTCGCAGTACCCGTTCAACTACAGTAAAAGTTGTTCAGACTACGgcagcatcttcatcttcatcttcgatTATCAAGCCAGAGAAGGTCGAGCCAGTTCGCGAACCGAATTCGACAAAAGCGCGTGCTGTGAAATCTCGTGCAGtaccagcaaaacaaacaaaaccggacGATGATAGCATACCGATCTTCCTTAGCGATGCCATGCTCATGGAGAAGATTTCGGAACTGCTGCAAATGCTGATCGGCGAAGAAATGTTGAAGGAGTTCGGTTGGCCTAAAGCACCGGTCGATGAGGTGCTGGTTCGGGTCATTAGTCGTTGTGGTCATCAACCGGCTAAAGGCGAGGAGGTGGGTGATCATACCACGCGTATGCGTGAAAACACTAAAATCCTGTTCTCCgtgacgatggatgatggtgacgtGAAGGCGCTGCTTAATAATCATACCTTGGACGAGGTCATCATGCATGTTCTGAAAAGCAAATAG
Protein Sequence
MATRASLRAAPKKKEEILVKMRINEENDIDVVPVVKDMYDSDSDSEEGNPSDQLDFEPELVETSDGRMMLELKRNKCCVRCKKPFTTLEAQKAHRSECTGVVDEMHDVIQKERKAAKYANPGEEFHKYCNPNPENPCYCCGEDVSTAHVGHIRCRLCPKSFKAYEYLDRHIKSIHAESEAYACANCNAKCCSQSVLDEHVKTHSEGKPFSCIACGKDFTRRYHLERHIKFSNCGTERKETLPCDVCGKVFTRVDNLREHLRTHMGQSVRKRDYQCPHCPKSFYGSSLLNIHIRTHTGEKPFPCDLCPSSFPSTGALRKHRRKHTGERPYRCDECSATFAARETLNRHRKTHTGDKRHVCPECGKRFIQATQLRTHIYKHTGKSDFKCGQCDMMFLRRNQLTEHIQLVHQGKEPLKCDYCDKEYLRKEDLQRHRAQHTGEKNYQCPTCLKTFALKTALSIHMKTHLQPEPVTCTICNGSFIRPDCLVRHMKAKHRVDCKELLEQQDESPVASPEVANGAMVEINGEVYQITSMDEQVAEPMLPEGVEFMELDIVAEESVETTEAATIITGDDVDSDQEYADEILEAVPELVNVKQEPVVVEVKKNRTELLTKSIPKMKAENTSTTSPTVANEIRSTRSTTVKVVQTTAASSSSSSIIKPEKVEPVREPNSTKARAVKSRAVPAKQTKPDDDSIPIFLSDAMLMEKISELLQMLIGEEMLKEFGWPKAPVDEVLVRVISRCGHQPAKGEEVGDHTTRMRENTKILFSVTMDDGDVKALLNNHTLDEVIMHVLKSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00098514;
90% Identity
-
80% Identity
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