Adar010142.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles darlingi
Gene Symbol
-
Assembly
GCA_000211455.3
Location
scaffold:110169-148632[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 1.8e-06 0.00011 21.7 4.9 1 23 147 169 147 169 0.98
2 26 8.9e-09 5.3e-07 29.0 3.3 1 23 175 197 175 197 0.98
3 26 7.1e-08 4.2e-06 26.2 4.6 1 23 203 225 203 225 0.98
4 26 2.6e-05 0.0016 18.1 8.2 1 23 231 253 231 253 0.97
5 26 1.2e-06 6.9e-05 22.3 5.6 1 23 259 281 259 281 0.98
6 26 4.8e-06 0.00029 20.4 5.9 1 23 287 309 287 309 0.98
7 26 1.1e-06 6.6e-05 22.4 5.8 1 23 315 337 315 337 0.98
8 26 7.7e-08 4.6e-06 26.1 4.7 1 23 343 365 343 365 0.99
9 26 5.2e-06 0.00031 20.3 3.4 1 23 371 393 371 393 0.98
10 26 1.3e-05 0.00075 19.1 5.9 1 23 399 421 399 421 0.98
11 26 3.1e-06 0.00018 21.0 2.7 1 23 427 449 427 449 0.99
12 26 2.3e-06 0.00013 21.4 2.3 1 23 455 477 455 477 0.97
13 26 6.4e-07 3.8e-05 23.2 5.0 1 23 483 505 483 505 0.98
14 26 7.5e-07 4.4e-05 22.9 3.7 1 23 511 533 511 533 0.98
15 26 3.3e-07 1.9e-05 24.1 5.9 1 23 539 561 539 561 0.98
16 26 2.5e-05 0.0015 18.1 7.1 1 23 567 589 567 589 0.98
17 26 6.7e-06 0.0004 19.9 6.7 1 23 595 617 595 617 0.98
18 26 2.9e-07 1.7e-05 24.2 5.1 1 23 623 645 623 645 0.98
19 26 1.2e-06 7e-05 22.3 5.7 1 23 651 673 651 673 0.98
20 26 2.4e-05 0.0014 18.2 6.7 1 23 679 701 679 701 0.98
21 26 7.1e-08 4.2e-06 26.2 4.6 1 23 707 729 707 729 0.98
22 26 2.8e-07 1.7e-05 24.3 7.7 1 23 735 757 735 757 0.98
23 26 1.9e-05 0.0011 18.6 8.0 1 23 763 786 763 786 0.95
24 26 1.6e-05 0.00094 18.8 0.6 1 23 792 814 792 814 0.98
25 26 0.0017 0.1 12.4 3.8 1 23 824 846 824 846 0.99
26 26 0.00062 0.037 13.8 4.3 1 23 852 875 852 875 0.96

Sequence Information

Coding Sequence
ATGCAGGTTCACCCGGCACACAGCGGCAGCGGAGGACATCATCCGCCACCGCCGCCGGCCCAGGGACCACCGCAGTCCGCTCATCCACCGCCGCCACAACCGATCCCGATTGTGAAGCCGGAGTTCAAGGTGCCGCCGATACCAGCGCACCTGATGGATGTGCGCGGTCCGGACGGATCGATTGTGAAGATCAACATGCCCGAGCATCACGATCCCAGCAAACCTCCGAACAACGTCGAGATGCTGAAGGTGAACATCGAGGATCTCAGCCAGTTTCTGTCGTACCACGAGGTCTTCGGCAAGCTGCCCTCCGACATGCTAACGGGTCCCTCCGCTAGCCTAGTGCCATCATCGTCCACCAATACGCCGACTACCAGTGCGCACAGCAATGGTAAATCGGGGAATCATCTCCGCAATCCGATTACCGGCGAATCTCCGTTCAAGTGTAGCTACTGCGCGAAAAGTTTCACTCGGAAGGAACACCTGACCAACCACGTTCGCCAGCACACCGGTGAATCGCCTTACCGATGTCCGTACTGCGGCAAGACGTTCACTCGGAAGGAGCATCTTACCAATCACGTCAGATTGCACACAGGCGAAACACCCTACCAGTGCACATACTGCGGGAAGAAGTTCACGAGAAAAGAACACCTTACCAATCATGTCAGATTGCATACTGGCGAAACTCCTTTCCACTGCACTTACTGTGAAAAGAAGTTTACGCGCAAAGAACATTTGACCAATCACACGAGGTTGCACACCGGCGAGACTCCCTTTCAATGTTCTTACTGTCAGAAGAAGTTCACTCGCAAAGAGCATTTAACGAACCATGTCAGGTTGCACACCGGAGAGACACCTTTTCAGTGTTCTTACTGTCAGAAGAAGTTCACTCGCAAAGAACATTTAACGTACCACGTCAGGTTGCATACCGGCGAGACTCCCTTTCAGTGTACTTACTGTCaaaaaaaGTTCACCCGTAAAGAACATTTAACAAACCATGTCAGGTTACACACCGGCGAAACTCCTTACCAGTGTACCTACTGTGACAAGAAGTTCACTCGCAAAGAGCACCTCACAAATCACGTCAGAATACACACTGGAGAGACTCCCTATCGGTGCACATATTGTGAGAAGAAGTTTACCAGAAAAGAACGGTTAACGTATCACATAAGATGGCATACGGGAGAAACTCCATACCATTGCACGTACTGCGAGAAAAAGTTCGCAAGAAAAGAACACTTAACCAATCACGTCAGATTGCACACAGGAGAGACCCCTTATCAGTGCACATATTGTGaaaaaaaaTTCAGTAGAAGAGAGCGTTTAACGATTCACACAAGAATCCATACCGGAGAGACTCCGTACGCATGCACGTATTGTGATAAAAAATTTAGCCGAAAAGAACGTTTGACGTATCACATAAGGTTACACACTGGAGAAACTCCCTATCAGTGCACGTATTGCGAGAAAAAGTTTACCCGAAAAGAGCACCTAACCAATCATGTCAGACTGCACACCGGCGAAACTCCCTATCCGTGCACGTATTGTGAGAAAAAGTTTACCCGAAAAGAGCACCTTACAAACCACGTCAGATTGCACACCGGAGAGACCCCTTATCAGTGCACGTATTGTGACAAAAAGTTCACTCGTAAAGAGCATTTGACTAATCATACAAGATTGCACACCGGAGAAACTCCCTATCATTGCACCTATTGTGAGAAGAAATTTATGCGCAAAGAACATTTAAAGAACCATATCAGATTGCATACCGGAGAAACTCCTTACCAATGTACGTTCTGCCAGAAGAAATTCACGCGAAAAGAGCATTTAACGAATCACACCAGATTGCATACAGGCGAAACTCCATACACGTGCACGTATTGTGACAAAAAGTTCACTCGCAAAGAGCACCTCACGAATCATGTCAGATTACACACCGGCGAGACTCCCTACACGTGTACCTATTGTCAGAAGAAGTTCACACGTAAAGAGCATTTGACGAATCACGTCAGATTACACACTGGCGAGACTCCGTATCATTGCACCTATTGCGAGAAGAAGTTTATGAGAAAAGAACATCTAACGAATCACATCAGATTGCACACCGGAGAAACTCCCTATCAGTGCACGTATTGCGGGAAGAAATTCACCCGAAAAGAGCATTTAACAAATCATGTCAGACTGCACACCGGAGATTCGCCACATAAATGCGAATATTGCAACAAGACGTTCACCCGGAAGGAACACCTGAACAATCATATGCGCCAGCACAGCGGTGATAACCCGCATTGTTGCAACGTATGCAACAAGACCTTTACTCGGAAGGAACACCTGATAAATCACATGAGCCGATCGCACACCGGTGAGCGACCCTTTCAATGCGACGAATGTGGAAAATCTTTCCCACTGAAGGGCAATCTGTTGTTCCATCAGCGCAGCCACACCAAGGGCCAACCCATGGAGCGCCCGTTCCGGTGCGATATGTGCCCGAAGGATTTTATCTGCAAGGGGCATCTGGTATCGCATCAGCGCTCGCACACGGGCGAGAAGAACCATCACTGTCCGCAGTGCAGCAAATCGTACGTCGAGCGGGGCAACATGCTGCGGCACATGAAAAAGACGCACCCGGACGCGGTCCTCCCAGTTCTACCGAAGCTGCCGCACATTAAGGTCGAACCGAAGTCTACTGTATCTCAGCCCACGTCCGTGGTGACGTCGCCGGCTCAAGCCGCTGCAACAATAACGTCGATTATCGCCAATACTCACCCATCGCAGCATCATCACATTCAACCGAAAATGGAACAGAAATCTCAGATACATCATCTTCCGATTCCTCATCAGCATCAAGCTCACCAGCTGCACCACCACATCTCGGGCCCGATGCATCTGCCGCCGCCAAACCCGCAGCAGTTGGCAGCGCTCGCCCTCCATCATCAGGCCcaacaacagcaacagcagcagcaacagcCGCCGCAATCTTCGCCTTCAACGGGACGAACCCAGCCATCCCCTCGTACATCACATCAGCCGCATCCTCAGCAGCAGCCACAGCCGCCGCCGCAGCCGGAAAACCTCCAGCAACCGGGACCGGGCCCGGCTGGACCCCTGCCACCTCAGCACCATACGGTCCCGGTTACTATTATAACCCATGCTGGAAACATTAATCCGATGCCGCAGGACGGTGGACTGGGGAACAATCGCGTTGGCGCTATACAGATGCATCACCTGAACGCAGCGGCCCAGCAGTCGGAGGAGCACTCGGTGGTCTACTGA
Protein Sequence
MQVHPAHSGSGGHHPPPPPAQGPPQSAHPPPPQPIPIVKPEFKVPPIPAHLMDVRGPDGSIVKINMPEHHDPSKPPNNVEMLKVNIEDLSQFLSYHEVFGKLPSDMLTGPSASLVPSSSTNTPTTSAHSNGKSGNHLRNPITGESPFKCSYCAKSFTRKEHLTNHVRQHTGESPYRCPYCGKTFTRKEHLTNHVRLHTGETPYQCTYCGKKFTRKEHLTNHVRLHTGETPFHCTYCEKKFTRKEHLTNHTRLHTGETPFQCSYCQKKFTRKEHLTNHVRLHTGETPFQCSYCQKKFTRKEHLTYHVRLHTGETPFQCTYCQKKFTRKEHLTNHVRLHTGETPYQCTYCDKKFTRKEHLTNHVRIHTGETPYRCTYCEKKFTRKERLTYHIRWHTGETPYHCTYCEKKFARKEHLTNHVRLHTGETPYQCTYCEKKFSRRERLTIHTRIHTGETPYACTYCDKKFSRKERLTYHIRLHTGETPYQCTYCEKKFTRKEHLTNHVRLHTGETPYPCTYCEKKFTRKEHLTNHVRLHTGETPYQCTYCDKKFTRKEHLTNHTRLHTGETPYHCTYCEKKFMRKEHLKNHIRLHTGETPYQCTFCQKKFTRKEHLTNHTRLHTGETPYTCTYCDKKFTRKEHLTNHVRLHTGETPYTCTYCQKKFTRKEHLTNHVRLHTGETPYHCTYCEKKFMRKEHLTNHIRLHTGETPYQCTYCGKKFTRKEHLTNHVRLHTGDSPHKCEYCNKTFTRKEHLNNHMRQHSGDNPHCCNVCNKTFTRKEHLINHMSRSHTGERPFQCDECGKSFPLKGNLLFHQRSHTKGQPMERPFRCDMCPKDFICKGHLVSHQRSHTGEKNHHCPQCSKSYVERGNMLRHMKKTHPDAVLPVLPKLPHIKVEPKSTVSQPTSVVTSPAQAAATITSIIANTHPSQHHHIQPKMEQKSQIHHLPIPHQHQAHQLHHHISGPMHLPPPNPQQLAALALHHQAQQQQQQQQQPPQSSPSTGRTQPSPRTSHQPHPQQQPQPPPQPENLQQPGPGPAGPLPPQHHTVPVTIITHAGNINPMPQDGGLGNNRVGAIQMHHLNAAAQQSEEHSVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00093593;
90% Identity
iTF_00092283;
80% Identity
iTF_00098505;