Basic Information

Gene Symbol
-
Assembly
GCA_013758885.1
Location
NC:67929069-67977745[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 2.6e-06 0.00012 21.6 4.9 1 23 147 169 147 169 0.98
2 28 1.3e-08 6e-07 28.9 3.3 1 23 175 197 175 197 0.98
3 28 1e-07 4.8e-06 26.1 4.6 1 23 203 225 203 225 0.98
4 28 3.7e-05 0.0018 18.0 8.2 1 23 231 253 231 253 0.97
5 28 1.6e-06 7.8e-05 22.3 5.6 1 23 259 281 259 281 0.98
6 28 6.8e-06 0.00032 20.3 5.9 1 23 287 309 287 309 0.98
7 28 1.6e-06 7.4e-05 22.3 5.8 1 23 315 337 315 337 0.98
8 28 1.1e-07 5.2e-06 26.0 4.7 1 23 343 365 343 365 0.99
9 28 7.3e-06 0.00035 20.2 3.4 1 23 371 393 371 393 0.98
10 28 1.8e-05 0.00085 19.0 5.9 1 23 399 421 399 421 0.98
11 28 4.3e-06 0.00021 20.9 2.7 1 23 427 449 427 449 0.99
12 28 3.2e-06 0.00015 21.4 2.3 1 23 455 477 455 477 0.97
13 28 9.1e-07 4.3e-05 23.1 5.0 1 23 483 505 483 505 0.98
14 28 1.1e-06 5e-05 22.9 3.7 1 23 511 533 511 533 0.98
15 28 4.6e-07 2.2e-05 24.0 5.9 1 23 539 561 539 561 0.98
16 28 3.6e-05 0.0017 18.1 7.1 1 23 567 589 567 589 0.98
17 28 9.6e-06 0.00045 19.9 6.7 1 23 595 617 595 617 0.98
18 28 4.1e-07 2e-05 24.2 5.1 1 23 623 645 623 645 0.98
19 28 1.7e-06 7.9e-05 22.3 5.7 1 23 651 673 651 673 0.98
20 28 2.8e-06 0.00013 21.6 6.7 1 23 679 701 679 701 0.98
21 28 3.4e-05 0.0016 18.1 6.7 1 23 707 729 707 729 0.98
22 28 1e-07 4.8e-06 26.1 4.6 1 23 735 757 735 757 0.98
23 28 2.6e-07 1.2e-05 24.8 5.7 1 23 763 785 763 785 0.98
24 28 4e-07 1.9e-05 24.2 7.7 1 23 791 813 791 813 0.98
25 28 2.6e-05 0.0013 18.5 8.0 1 23 819 842 819 842 0.95
26 28 2.2e-05 0.0011 18.7 0.6 1 23 848 870 848 870 0.98
27 28 0.0024 0.11 12.3 3.8 1 23 880 902 880 902 0.99
28 28 0.00088 0.042 13.7 4.3 1 23 908 931 908 931 0.96

Sequence Information

Coding Sequence
ATGCAGGTTCACCCGGCACACAGTGGAAGCGGAGGACAtcatccgccaccgccgccggcccAGGGACCACCGCAGTCCGCccatccgccgccgccgcaaccGATCCCGATTGTGAAGCCGGAGTTTAAGGTGCCGCCGATACCGGCGCATCTGATGGATGTGCGCGGTCCAGATGGGTCGATCGTGAAGATCAACATGCCCGAGCATCACGATCCGAGCAAACCGCCCAATAACGTCGAGATGCTGAAGGTGAACATCGAGGATCTCAGCCAGTTTCTGTCGTACCATGAGGTCTTCGGCAAGCTGCCCTCCGACATGCTATCGGGTCCCTCCGCTAGCCTAGTGCCATCATCGTCCACCAATACGCCGACTACCAGTGCGCACAGTAATGGTAAATCGGGGAATCATCTCCGCAATCCGATTACCGGCGAATCTCCGTTCAAGTGTAGCTACTGCGCGAAAAGCTTCACCCGGAAGGAACACCTGACCAATCACGTGCGCCAGCACACCGGTGAATCGCCTTACCGGTGTCCATACTGCGGCAAGACGTTCACTCGGAAGGAGCATCTTACCAATCACGTCAGATTGCACACAGGCGAAACACCCTACCAGTGCACATACTGCGGGAAGAAGTTCACGAGAAAAGAACACCTTACCAATCATGTCAGATTGCACACCGGCGAAACTCCTTTCCACTGCACATACTGTGAAAAAAAGTTTACTCGCAAAGAACATTTGACCAATCACACGAGGTTGCACACCGGCGAGACTCCCTTTCAATGTTCTTACTGTCAGAAGAAGTTCACTCGCAAAGAGCATTTAACGAACCATGTCAGGTTGCACACCGGAGAGACACCTTTTCAGTGTTCTTACTGTCAGAAGAAGTTCACTCGCAAAGAACATTTAACGTACCACGTCAGGTTACATACCGGCGAGACTCCCTTTCAGTGTACTTACTGTCAAAAAAAGTTCACGCGTAAAGAACATTTAACAAACCATGTCAGGTTACACACCGGCGAAACTCCTTATCAGTGTACCTACTGTGACAAGAAGTTCACTCGCAAAGAGCACCTCACAAATCACGTCAGAATACACACTGGAGAGACTCCCTATCGGTGCACATATTGTGAGAAGAAGTTTACCAGAAAAGAACGGTTAACGTATCACATAAGATGGCATACGGGCGAAACTCCTTACCATTGCACGTACTGCGAGAAAAAGTTCGCAAGAAAAGAACACTTAACCAATCACGTCAGATTGCACACAGGAGAGACCCCCTATCAGTGCACATATTGTGAAAAAAAATTCAGTAGAAGAGAGCGTTTAACGATTCACACAAGAATCCATACCGGAGAGACTCCGTACGCATGCACGTATTGTGATAAAAAATTTAGCCGAAAAGAACGTTTGACGTATCACATAAGGTTACACACTGGAGAAACTCCCTATCAGTGCACGTATTGCGAGAAAAAGTTTACCCGAAAAGAGCACCTAACCAATCATGTCAGACTGCACACCGGAGAAACTCCCTATCCGTGCACGTATTGTGAGAAAAAGTTTACCCGAAAAGAGCACCTCACAAACCACGTCAGATTGCACACCGGAGAGACCCCTTATCAGTGCACGtattgtgacaaaaagttcaCTCGTAAAGAGCATTTGACTAATCACACAAGATTGCACACCGGAGAAACTCCCTATCATTGCACCTATTGCGAGAAGAAATTTATGCGCAAAGAACACTTAAAGAACCATATCAGATTGCATACCGGAGAAACTCCTTACCAATGTACGTTCTGCCAGAAGAAATTCACGCGAAAAGAGCATTTAACGAATCACACCAGGTTGCATACGGGCGAAACTCCCTACACGTGCACGTATTGTGACAAGAAGTTCACCCGCAAAGAGCACCTCACGAACCACGTCAGATTACACACCGGCGAGACTCCCTACACGTGTACCTATTGTCAGAAGAAGTTCACACGTAAAGAGCATTTGACGAATCACGTCAGATTGCACACTGGCGAAACTCCCTTCCAGTGCACATATTGCCAGAAAAAGTTTACGAGAAAAGAGCATTTGACGAATCATACCAGATTACACACTGGCGAGACTCCGTATCATTGCACCTATTGCGAGAAGAAGTTTATGAGAAAAGAACATCTAACGAATCACATCAGATTGCACACCGGAGAAACTCCCTATCAGTGCACGTATTGCGGGAAGAAATTCACCCGAAAAGAGCATTTAACAAATCATGTCAGATTACATACCGGAGAGTCTCCGTACCGGTGTTCGTACTGTACCAAGTCATTCACCAGAAAAGAGCACCTCAAGAACCACATCAGACTGCACACTGGAGATTCGCCGCACAAATGCGAGTATTGCAACAAGACGTTCACCCGGAAGGAACATTTGAACAATCACATGCGCCAGCATAGTGGCGATAACCCACATTGTTGTAACGTATGCAACAAGACTTTCACTCGCAAGGAGCACCTGATAAATCACATGAGCCGATCGCACACCGGTGAGCGACCCTTTCAATGCGACGAATGTGGAAAATCTTTCCCACTGAAGGGCAATCTGTTGTTCCATCAGCGCAGCCACACCAAGGGCCAACCCATGGAGCGCCCGTTCCGGTGCGATATGTGCCCGAAGGATTTTATCTGCAAGGGGCACCTAGTATCGCATCAGCGCTCGCACACGGGCGAGAAGAACCATCACTGTCCGCAGTGCAGCAAATCGTACGTCGAGCGGGGCAACATGCTGCGGCACATGAAAAAGACGCACCCGGACGCGGTCCTCCCAGTTCTACCGAAGCTGCCGCACATTAAGGTCGAACCGAAGTCTACCGTATCTCAGCCCACGTCCGTGGTGACGTCGCCGGCTCAGGCCGCTGCAACAATAACGTCGATTATCGCCAATACTCACccatcgcagcatcatcacatTCAACCGAAAATGGAACAGAAATCTCAGATACATCATCTTCCGAttcctcatcagcatcaagctcaccagctgcaccaccacatCTCGGCCCCGATGCATCTGCCACCGCCAAACCCGCAGCAGTTGGCAGCGCTCGCCCTCCATCATCAggcccaacaacagcaacagcagcagcaacagccgccgcAATCTTCGCCTTCAACGGGACGAACCCAGCCATCCCCTCGTACATCACATCAGCCGcatcctcagcagcagcaacagccgccgccgcagccggaAAACCTCCagcaaccgggaccgggcccgGCTGGACCCCTGCCACCTCAGCACCATACGGTCCCGGTTACTATTATAACCCATGCTGGAAACATTAATCCGATGCCACAGGACGGTGGACTGGGAAACAATCGTGTTGGCGCCATACAGATGCATCACCTGAACGCGGCGGCACAGCAGTCGGAGGAGCACTCGGTGGTGTACTGA
Protein Sequence
MQVHPAHSGSGGHHPPPPPAQGPPQSAHPPPPQPIPIVKPEFKVPPIPAHLMDVRGPDGSIVKINMPEHHDPSKPPNNVEMLKVNIEDLSQFLSYHEVFGKLPSDMLSGPSASLVPSSSTNTPTTSAHSNGKSGNHLRNPITGESPFKCSYCAKSFTRKEHLTNHVRQHTGESPYRCPYCGKTFTRKEHLTNHVRLHTGETPYQCTYCGKKFTRKEHLTNHVRLHTGETPFHCTYCEKKFTRKEHLTNHTRLHTGETPFQCSYCQKKFTRKEHLTNHVRLHTGETPFQCSYCQKKFTRKEHLTYHVRLHTGETPFQCTYCQKKFTRKEHLTNHVRLHTGETPYQCTYCDKKFTRKEHLTNHVRIHTGETPYRCTYCEKKFTRKERLTYHIRWHTGETPYHCTYCEKKFARKEHLTNHVRLHTGETPYQCTYCEKKFSRRERLTIHTRIHTGETPYACTYCDKKFSRKERLTYHIRLHTGETPYQCTYCEKKFTRKEHLTNHVRLHTGETPYPCTYCEKKFTRKEHLTNHVRLHTGETPYQCTYCDKKFTRKEHLTNHTRLHTGETPYHCTYCEKKFMRKEHLKNHIRLHTGETPYQCTFCQKKFTRKEHLTNHTRLHTGETPYTCTYCDKKFTRKEHLTNHVRLHTGETPYTCTYCQKKFTRKEHLTNHVRLHTGETPFQCTYCQKKFTRKEHLTNHTRLHTGETPYHCTYCEKKFMRKEHLTNHIRLHTGETPYQCTYCGKKFTRKEHLTNHVRLHTGESPYRCSYCTKSFTRKEHLKNHIRLHTGDSPHKCEYCNKTFTRKEHLNNHMRQHSGDNPHCCNVCNKTFTRKEHLINHMSRSHTGERPFQCDECGKSFPLKGNLLFHQRSHTKGQPMERPFRCDMCPKDFICKGHLVSHQRSHTGEKNHHCPQCSKSYVERGNMLRHMKKTHPDAVLPVLPKLPHIKVEPKSTVSQPTSVVTSPAQAAATITSIIANTHPSQHHHIQPKMEQKSQIHHLPIPHQHQAHQLHHHISAPMHLPPPNPQQLAALALHHQAQQQQQQQQQPPQSSPSTGRTQPSPRTSHQPHPQQQQQPPPQPENLQQPGPGPAGPLPPQHHTVPVTIITHAGNINPMPQDGGLGNNRVGAIQMHHLNAAAQQSEEHSVVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2