Adar000636.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles darlingi
Gene Symbol
Hr39
Assembly
GCA_000211455.3
Location
scaffold:156689-189499[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 1e+04 -10.0 14.1 43 166 54 201 11 224 0.56
2 4 0.26 1.4e+03 -2.4 0.3 63 73 283 293 257 331 0.50
3 4 2e-08 0.0001 21.1 0.0 1 21 400 420 400 437 0.86
4 4 3.4e-78 1.8e-74 250.9 0.0 176 408 545 773 505 773 0.91

Sequence Information

Coding Sequence
atgatcagcagcagcagcagcacacaacaccatcagcagcagcatcagcaccaccttcatcatgcacaccagcatctgctgcaaccggaagcactcactagtggtccgggtataaccgagccgctggcactaacgacaaaccatcagcagcatcaccatcagcatcaccagcagcagcaccagcagcagcaacatggtgctcctGGTGTCACCTATCGATCGTCCGGTAGTAGCGCCAGTAATAACTCACCCCTACCCTCCTCGGGCCGGTTGGTGATCAAACCCGAATCCGGGCTGCCACTGATCAATCCCGGTCTGGCGTACAACGTTGGACCAGCAGCACCACCGTCGACAAACATTCCATCATCGGCACCGAGCGGTTCGGTGGGAACGGTCTCCGTGAAGAAGCTACCGGATGTGATCAACCTCAAGTATGAACTGCCAACGACGGAACCATCCGGTGGTGCGTCCAGCATACATTCGCCGTTGCTCGTTCGCTCAAAAACGACACTGCTACCGGCGAACCCGAGCCCCGATTCGGCCATCCATTCGGTGTACACACACAGCTCACCGAGCCAATCGCCGCTAACGTCACGGCATGCACCGTACACACCTTCGTTGAGCCGGAACAACAGTGATGCATCGCACAGTAGCTGCTACTCGTACTCGTCCGAGTTTAGCCCAACGCATTCACCGATCCAGGGGCGCCATAGTATCTTCGGTGGTGGCGGTGGTGGAGCGGGTGGCATGGGTAGTAATGGACCGAGTGCCTCCTTTAATGGGTCACCCCTGCATCACTCAGTATTATTTAAGCCGATGCTGGACGCCAGCGAGCAACAGGCGCACCAGCACCAGCATCAACAGCAGCAACAACAGGCAGCGCTGAAGCAGTTGGCGGCAGCGGCCGCAGCCTCCCAGGAGGAGCCACTCTACGAAGGGGACCATCTACCATCGCCTGGCATATCGAGGCAACAGCTCATCAACAGTCCTTGTCCGATCTGCGGTGACAAGATATCTGGCTTCCACTATGGCATTTTCTCGTGCGAATCGTGCAAAGGGTTCTTCAAGCGGACGGTCCAGAACCGGAAGAATTACGTGTGCCTTAGGGGAGCAGCCTGCCCGGTAACGATAGCAACGCGCAAAAAGTGTCCCGCCTGCCGCTTCGAGAAGTGCCTTCAGAAGGGAATGAAGCTGGAAGCCATTCGAGAGGATCGTACGCGTGGAGGTCGCTCGACGTATCAGTGTTCGTACACGCTTCCCGGTCCGCTGGTGAGCGCCAGCAGTGGCATGCAGTCAGGCAGTGATTCACCAGTGACCGGTCCATTCCAATATGGTGGCAATTCGGGGGTTCGCTCATCACCGTACggtggtggtgttggtggtggtcccggtagtggtggCCATCCGATGAAGCTTGAACCAGGTGACGGTGGATCCGGTGGACTAATGATGACCGGCGGTAACGGTGGTAGTGGTGGCGGCAATGGTCTAAACGGTATGAACATGGATCGTATGGGATCGAACGGTGAAGCCGGAGGACCGAGCAGTGGCAACCATCTACCACCAGGCATTCCAGTGCTGCTACAGGAAATTATGGACGTGGAACCGTTGTGGCAGTACAACGCGGCCGAGCTGGCACGGCTCAATCAACCACCGCCCGCGGTCAGCAGTGCAGCGATCGCAAGCAATCCCCTGCTCTCTAGTGCTGGCATTTCGTCCGAAAGCAGCCCCGATCTGATCGCTAACCTGTGCAACATTGCCGATCATCGATTGTACAAGATCGTCAAGTGGTGCAAGAGTTTGCCACTCTTTAAGAACATTTCGATTGATGACCAGATCTGCCTGCTGATCAACTCGTGGTGTGAGCTGCTTCTGTTCTCCTGCTGCTACCGTTCGATCGCGACACCGGGCGAGATCAAAATCTCCCTCGGCAAGTCGATAACGCTGGAGCAGGTCAAGAACAGTGGGTTGCAGACCTGCATCGAACGTATGCTTCACCTGACGGACCATCTGCGAAGGCTACGGGTCGATCGATATGAGTACGTCGCGATGAAGGTGATCGTTCTGCTCTCTTCCGATACCTCCGAGCTGAAGGAATCGGAGAAGGTACGAGCCAGCCAGGAGAAAGCTCTGCAGGCGCTGCAGGCGTACACCCTAGCTTACTACCCGAAGTCACCGGCCAAGTTTGGTGAGCTGTTGCTGCGCATTCCAGAACTACAACGGACGTGTCAGGTCGGTAAGGAGATGCTGACGATCAAATCGAAGGACGGTGAAGAACCATCGTTTAATCTGCTGATGGAGCTGCTCCGTGGCGAACATTGA
Protein Sequence
MISSSSSTQHHQQQHQHHLHHAHQHLLQPEALTSGPGITEPLALTTNHQQHHHQHHQQQHQQQQHGAPGVTYRSSGSSASNNSPLPSSGRLVIKPESGLPLINPGLAYNVGPAAPPSTNIPSSAPSGSVGTVSVKKLPDVINLKYELPTTEPSGGASSIHSPLLVRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSIFGGGGGGAGGMGSNGPSASFNGSPLHHSVLFKPMLDASEQQAHQHQHQQQQQQAALKQLAAAAAASQEEPLYEGDHLPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGPLVSASSGMQSGSDSPVTGPFQYGGNSGVRSSPYGGGVGGGPGSGGHPMKLEPGDGGSGGLMMTGGNGGSGGGNGLNGMNMDRMGSNGEAGGPSSGNHLPPGIPVLLQEIMDVEPLWQYNAAELARLNQPPPAVSSAAIASNPLLSSAGISSESSPDLIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIATPGEIKISLGKSITLEQVKNSGLQTCIERMLHLTDHLRRLRVDRYEYVAMKVIVLLSSDTSELKESEKVRASQEKALQALQAYTLAYYPKSPAKFGELLLRIPELQRTCQVGKEMLTIKSKDGEEPSFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00098448;
90% Identity
iTF_00098448;
80% Identity
iTF_00098448;