Acul008656.1
Basic Information
- Insect
- Anopheles culicifacies
- Gene Symbol
- Zfx
- Assembly
- GCA_000473375.1
- Location
- AXCM01005143:3629-5952[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 1.8 1e+02 3.4 0.1 2 23 325 346 324 346 0.92 2 12 5.9 3.4e+02 1.7 1.9 1 23 352 380 352 380 0.86 3 12 0.0026 0.15 12.2 1.2 3 23 386 406 384 406 0.96 4 12 3.3e-06 0.00019 21.4 2.2 1 23 411 433 411 433 0.98 5 12 3.3e-06 0.00019 21.4 0.9 1 23 441 463 441 463 0.99 6 12 0.025 1.4 9.2 7.7 1 23 469 491 469 491 0.96 7 12 0.007 0.41 10.9 0.6 2 20 498 516 497 520 0.87 8 12 0.2 12 6.3 0.3 2 23 547 571 547 571 0.95 9 12 8.9e-07 5.2e-05 23.2 0.4 1 23 575 597 575 597 0.97 10 12 1.2e-05 0.00072 19.6 1.1 1 23 603 625 603 625 0.98 11 12 3e-08 1.7e-06 27.8 1.2 1 23 631 653 631 653 0.98 12 12 0.00021 0.012 15.7 3.4 1 23 659 682 659 682 0.94
Sequence Information
- Coding Sequence
- ATGGAAGCCGCAAAAGCATCTAAACCAAGCAGCGGAATGACCGCGTCATCGCCAGCAGAGCGCAGCAAGCCAGTGGACGAAAAACAGGTAGCCGAAGCGTCGTCCGATGAGTTTTGTCGAATATGTTTGCTAAAATCTACCCAGCTCAAGCCCCTAATGGAGCGCGTGGATGGGGTTATGATACCGGAAATGCTGTACAAGCTGTGCGGCCGCCAGATTGAGGTCCAGGAAGGCTATCCGCGCAGCATCTGCCAACGGTGCTTGTGTCGTTTGGATTGTGCGTTTAGGTTTCTAAACGATTTTCACCAGCAAGACGAACGTTTGCGCAGCTTTTATTGGAGCGGTTCCGTAGCGAAAAGGCTACAGGAGTATCAAGTCGAGGGTAACGCGACTGCCAACAAGCGAATGGATGAACTAAACAGCCTGTATAAAGCGCTATTCAAGCAGCCCGCGAAGCAGATGTGTAACAAAGAAACCAACACGATCAAACAGAAATCTCCTAAAACGGCCGATGTAGGTACGATCACGGATAAGGAGTTGATTAATCTTCAACTCGTTAAAAGTGAAGACGATTCGGATGGTGAGATAATGCTGGAGCATTACGTTATGGAAGAGGACAATGAGGAAACGTATCTCGATTACTGTGTCGATGGCGAAACTACGCTCAAGGATCAACAGCTGGTGGCGATGAAAATAGACCTGCTTCAGTCGACGGACGAAGCCGAATCATGCAGTGAAGAAAAGCCGTCGAGAGCAAAAGAGATCAAAGGCACAAGACAACAGCAACAGCTGAGCAAAGCAACAAAGGTTAAGGTAGCTTTATCGGATACGATGGAAGAAAGCATACCGACCGATACAGATGATCCGGCACATGAACAAGTATACTACGAGGATACAGAAACTgagcaagaggaagaggaggaggaggaggaagaagaagaccaagagcaagaagggaaATTTGATGATCTTCGCTGTTATATTTGTGATATAAAAGAGGAAAATGAAGATCTGTTGGAGCAGCATCTCGATCTGCACAGTACGATGCTACCGTACGACTGCAAATCTTGTCATGCTGAAGGTGTATCAATCCGCACGATCAAAACCGTCTCCTCGCTGCACAATCACTTCCGCTCGCACCTTTACCCGTACTGGTGTGATATTTGTGGCAAACGCTACTTACGCAAAATGCAACTGAAAAAGCATAAGGAAAACCATACCAACAGTCTGTTTGTCTGCGATGAATGTGGTCGAGGGTTTACGCATAAGAAAACGTGGCAAAATCACATCAAACGCCACAAGGCGCTTCGTGCCGAAATGTACAAATGTAGCACGTGCGACAAAGCCTTTGGTAACAAGGCTCGATTGGACCGACATATGCGGTTACATACAGGCGATCGGCCGTTTGAGTGTAAGTATTGCGACAAGCGGTATTACGACCGTCACCAGCTGCAGTGCCACACGGAAAAGCACTTCCGGGAGGTTGATTGTGCGTGTGAGTATTGTGGCGAAACATTCGCGGGCACGAAGAAGCTCGAAGCACACAAGGTTGCGAAGCATCTGACTGGCAAGGAGTTGGATGATTATCTGGCCAACCGAGCGAAACGGACAAAACGGCAAGCGATCCTTAAGGATGAAACATGTCCATACCCGGATTGTAACTATAAGGCCAAAACGTACGGTGCGATGTATGTGCACAAGCGTACCAAACATGCGCCCATGCATCCGTGTGGGATCTGCGGCAAATCGTTCGCCTTCCAGAACCAGCTCGAGGTCCATATGAAGTTGCATACGGGTGAGAAACCGTTCCAGTGCGAATTATGTGGTCGCAGCTTCCGCCGTGGCTTTAGCTATCGGGAACATATGGAAATGCACACCTCGCAAGCAAGCTACAACTGTCCTACGTGTAACAAAAGCTTCAAGCGACCACGGTATCTGCAGGCGCACATGCTCACCCACACGTCGGAACGTAAATTTTCGTGCGAGATCTGTGGCAACTGTTACAAAACGAATGGGGAGCTGAAGAAGCACAACAAAAACAAGCACGGGCTTGATATTGTAGAGCAGGACGTGATCATCGAAACCGATGATCAGTACATTGTGGAGTACGTTTAG
- Protein Sequence
- MEAAKASKPSSGMTASSPAERSKPVDEKQVAEASSDEFCRICLLKSTQLKPLMERVDGVMIPEMLYKLCGRQIEVQEGYPRSICQRCLCRLDCAFRFLNDFHQQDERLRSFYWSGSVAKRLQEYQVEGNATANKRMDELNSLYKALFKQPAKQMCNKETNTIKQKSPKTADVGTITDKELINLQLVKSEDDSDGEIMLEHYVMEEDNEETYLDYCVDGETTLKDQQLVAMKIDLLQSTDEAESCSEEKPSRAKEIKGTRQQQQLSKATKVKVALSDTMEESIPTDTDDPAHEQVYYEDTETEQEEEEEEEEEEDQEQEGKFDDLRCYICDIKEENEDLLEQHLDLHSTMLPYDCKSCHAEGVSIRTIKTVSSLHNHFRSHLYPYWCDICGKRYLRKMQLKKHKENHTNSLFVCDECGRGFTHKKTWQNHIKRHKALRAEMYKCSTCDKAFGNKARLDRHMRLHTGDRPFECKYCDKRYYDRHQLQCHTEKHFREVDCACEYCGETFAGTKKLEAHKVAKHLTGKELDDYLANRAKRTKRQAILKDETCPYPDCNYKAKTYGAMYVHKRTKHAPMHPCGICGKSFAFQNQLEVHMKLHTGEKPFQCELCGRSFRRGFSYREHMEMHTSQASYNCPTCNKSFKRPRYLQAHMLTHTSERKFSCEICGNCYKTNGELKKHNKNKHGLDIVEQDVIIETDDQYIVEYV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00105328;
- 90% Identity
- -
- 80% Identity
- -