Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: KI422487:57528-61734[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.013 0.74 10.1 4.2 2 23 353 375 352 375 0.95

2 11 8.9e-06 0.00052 20.0 2.1 1 23 380 402 380 402 0.98

3 11 0.00011 0.0062 16.6 1.0 1 23 408 430 408 430 0.98

4 11 1.6e-05 0.00094 19.2 0.9 1 23 436 458 436 458 0.98

5 11 0.0001 0.006 16.7 1.1 1 23 464 486 464 486 0.96

6 11 2.4e-08 1.4e-06 28.1 1.6 1 23 492 514 492 514 0.99

7 11 8.8e-07 5.1e-05 23.2 0.3 1 23 520 542 520 542 0.98

8 11 5.7e-05 0.0033 17.5 0.3 2 23 552 573 551 573 0.97

9 11 9.1e-05 0.0053 16.8 1.7 3 23 581 601 579 601 0.98

10 11 7.1e-05 0.0041 17.2 0.4 1 23 607 629 607 629 0.93

11 11 2.5e-05 0.0015 18.6 2.5 1 23 635 657 635 657 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.013	0.74	10.1	4.2	2	23	353	375	352	375	0.95
2	11	8.9e-06	0.00052	20.0	2.1	1	23	380	402	380	402	0.98
3	11	0.00011	0.0062	16.6	1.0	1	23	408	430	408	430	0.98
4	11	1.6e-05	0.00094	19.2	0.9	1	23	436	458	436	458	0.98
5	11	0.0001	0.006	16.7	1.1	1	23	464	486	464	486	0.96
6	11	2.4e-08	1.4e-06	28.1	1.6	1	23	492	514	492	514	0.99
7	11	8.8e-07	5.1e-05	23.2	0.3	1	23	520	542	520	542	0.98
8	11	5.7e-05	0.0033	17.5	0.3	2	23	552	573	551	573	0.97
9	11	9.1e-05	0.0053	16.8	1.7	3	23	581	601	579	601	0.98
10	11	7.1e-05	0.0041	17.2	0.4	1	23	607	629	607	629	0.93
11	11	2.5e-05	0.0015	18.6	2.5	1	23	635	657	635	657	0.99

Sequence Information

Coding Sequence: ATGGCCAACCTGTCGACTGATGCTAGAATGGAAGGAAAACCTACAGCAAAAGCTTCAACGATGAAGATTGGGATATCGCGAACTACTCGTGCATGGGCGCCACCAAGTGCCGATCCTAGAATCATTTACTTGGACCGTGTTTGCCGAACGTGCCTGAGCGAAAAGGAAAAGAATCAACTAAAGGATCTGTTCGAATTGAGCCTCGCAGAAACGATCATGAGTTGCACAAGCTTGACGGTCACTGAATCCGATGGACTTCCTTGCCATATCTGCACGGACTGTTGTATGGAGCTGGAGCGAAGTTTCAATTTTCGACAAATGTCCAAAGCGTCCGATGCAACGATACGATCGTTGATTGAAAAATCGGTCGTTATTAAGCAGGACAGTGAAACCAAGTACGAGGTGTTAAATGTTGTTCTTACCGACTCGGACGGTAACACGGAAACATCCGCCGTCGTTGTACCAATAGAGGAGCTTCGCTTTCAGCTGATGAACACAAACCGCGCGGTAGTGGAAGCGAAAGCTGAGGGCAATATCGCGATCCGCGATCGGAAAGCAAGCCAAATACATTCTGCGCAACTGAATAGTACAATTACACTGGATCCCAGTCCCAACGGTAAGGAGACGGGTGTTGGAGAAGAACTTTCAGTAAATCCTAACGATCTCCTAAATGAGCCAATTCCTACGACGACCCTGAACAAAGAAGCCGCCGCACCAGCTCAAACGCAAGCACTAAGGGAATCGACCATTCTTCGTAACCTGAAACAGGAGTTGTCCGAGTTTATTGGTAGCAATTGTACTGCCATTTCGAAGGAAGTAGAAATTGTAGATGAGAATGAGGACGATGAACTGATCCATGTGGACTATCTAAAGGATGCGCTTACTGAGGAATACATTCAGATCATGGAGACGCAACTGGCGTCTGCTGCTGTGGCGGGCAACAAAGAAGAGCAGCTCGAGCAGGAACATTTGAACAATTTAATTCACGCATCAATGGAAGCGGAAGATCCTCGCGATCGTCATAAACCAGATGAATGTCTTGAACGGGATACAACGCATTGCAAGATATGTGATGTCCAATTTAACAAACGTAAGCTGTACCAAAAACACGTCAATCGAAAACATTCCGAGAAACGTTTTGAATGTAATCATTGCCCAAGAAAATTTGCGGAAAAGTCCGTTCTCAAGAATCATATGCTGCGTCATACTGGGGAAAAAACGCACGTTTGTGATGTGTGTGAGGCACGGTTTTACGAAAAGACTTTACTGAACGTGCACATGCGAAGGCACACGGGTCTACGGCCGTACGCTTGCGAGTTGTGCGACAAACGCTTTACTACTCGCAGCATTCTCAACACACACCAAAAAGTGCATAACGATCCGCGGCCTCACATATGCAATGTTTGCCAGAAAGGATTCAAGCTATCTTGGCAACTAAAAGCTCACAGTCGAGTACACACCGATGAGAAACCCTTCGAATGTCCCTACTGCCACAAACGGTTCAACCAAAATGGTAACTTGGTCGTACATATACGCACCCATTCGGGAGAAAAACCATTCAAATGTAAAGTCTGCGATAAGGCATATCCTAGCCAGGGTGAGCTAAGGGGACATATGCGCCAGCATACGGGAGAGGAAAGGGCCaagaaagtggtatgcaccatctgcagcaaagcgttttctgccaaccacgtgctggtaatccacatgcgcacacacaccaaggaaaagccgtatggttgtacggtttgcgagaagcggttcatgatgcgtgtacatctcacagtccatatgcggtcgcacacgggcgaaaaaccattcgcatgcaatgtgtgcgaaaaggCATTTCCTACCAATTATCAGTTGAAAATGCACAACTACGTGCATACGGGTGAGAAGAATTACTCCTGTGATGTTTGTAACCGTAAATTTAGCAGCTCAGCCAACCGGAATACGCATCGGAAAACACATGATCGGAAGACAAATTAA
Protein Sequence: MANLSTDARMEGKPTAKASTMKIGISRTTRAWAPPSADPRIIYLDRVCRTCLSEKEKNQLKDLFELSLAETIMSCTSLTVTESDGLPCHICTDCCMELERSFNFRQMSKASDATIRSLIEKSVVIKQDSETKYEVLNVVLTDSDGNTETSAVVVPIEELRFQLMNTNRAVVEAKAEGNIAIRDRKASQIHSAQLNSTITLDPSPNGKETGVGEELSVNPNDLLNEPIPTTTLNKEAAAPAQTQALRESTILRNLKQELSEFIGSNCTAISKEVEIVDENEDDELIHVDYLKDALTEEYIQIMETQLASAAVAGNKEEQLEQEHLNNLIHASMEAEDPRDRHKPDECLERDTTHCKICDVQFNKRKLYQKHVNRKHSEKRFECNHCPRKFAEKSVLKNHMLRHTGEKTHVCDVCEARFYEKTLLNVHMRRHTGLRPYACELCDKRFTTRSILNTHQKVHNDPRPHICNVCQKGFKLSWQLKAHSRVHTDEKPFECPYCHKRFNQNGNLVVHIRTHSGEKPFKCKVCDKAYPSQGELRGHMRQHTGEERAKKVVCTICSKAFSANHVLVIHMRTHTKEKPYGCTVCEKRFMMRVHLTVHMRSHTGEKPFACNVCEKAFPTNYQLKMHNYVHTGEKNYSCDVCNRKFSSSANRNTHRKTHDRKTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00103822;
90% Identity: iTF_00105285;
80% Identity: -