Basic Information

Insect: Anopheles culicifacies
Gene Symbol: -
Assembly: GCA_000473375.1
Location: AXCM01000345:8777-12335[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00015 0.0089 16.1 0.8 1 23 235 257 235 257 0.99

2 15 0.002 0.12 12.6 4.7 1 23 266 288 266 288 0.96

3 15 1.6e-06 9.1e-05 22.4 0.2 1 23 297 319 297 319 0.98

4 15 2.6e-05 0.0015 18.6 4.4 1 23 325 347 325 347 0.98

5 15 0.015 0.86 9.9 0.1 2 23 355 376 354 376 0.97

6 15 0.00028 0.016 15.3 3.3 1 23 382 405 382 405 0.94

7 15 0.0025 0.15 12.3 6.1 1 21 411 431 411 432 0.94

8 15 0.24 14 6.1 4.6 3 23 440 461 438 461 0.94

9 15 7.2e-06 0.00042 20.3 0.6 1 23 504 526 504 526 0.97

10 15 3e-05 0.0017 18.4 0.4 1 23 537 559 537 559 0.97

11 15 7.2e-05 0.0042 17.2 4.3 1 23 589 611 589 611 0.99

12 15 0.61 35 4.8 4.2 2 23 646 667 645 667 0.94

13 15 0.0011 0.063 13.5 4.9 1 23 673 695 673 695 0.98

14 15 3.8e-07 2.2e-05 24.3 1.5 1 23 703 725 703 725 0.99

15 15 0.00019 0.011 15.8 0.7 1 23 731 754 731 754 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00015	0.0089	16.1	0.8	1	23	235	257	235	257	0.99
2	15	0.002	0.12	12.6	4.7	1	23	266	288	266	288	0.96
3	15	1.6e-06	9.1e-05	22.4	0.2	1	23	297	319	297	319	0.98
4	15	2.6e-05	0.0015	18.6	4.4	1	23	325	347	325	347	0.98
5	15	0.015	0.86	9.9	0.1	2	23	355	376	354	376	0.97
6	15	0.00028	0.016	15.3	3.3	1	23	382	405	382	405	0.94
7	15	0.0025	0.15	12.3	6.1	1	21	411	431	411	432	0.94
8	15	0.24	14	6.1	4.6	3	23	440	461	438	461	0.94
9	15	7.2e-06	0.00042	20.3	0.6	1	23	504	526	504	526	0.97
10	15	3e-05	0.0017	18.4	0.4	1	23	537	559	537	559	0.97
11	15	7.2e-05	0.0042	17.2	4.3	1	23	589	611	589	611	0.99
12	15	0.61	35	4.8	4.2	2	23	646	667	645	667	0.94
13	15	0.0011	0.063	13.5	4.9	1	23	673	695	673	695	0.98
14	15	3.8e-07	2.2e-05	24.3	1.5	1	23	703	725	703	725	0.99
15	15	0.00019	0.011	15.8	0.7	1	23	731	754	731	754	0.97

Sequence Information

Coding Sequence: ATGGAATACAACAATGTCTACAATAAACCGTACTGTGGTGTTATTTCCCAGCCGATAGCACCAACCGCCAGCTCTGGTTACTTTCCGGCAAATGACACTACACCGACGTTCCTTAAAGTACCCAATCCACCGTACATCAAGCAGGAGTCGGGTACGGTGGGCAGTGATACGGTAATTATTGGCGGAACCATAACACCACCAGTAAACTACAGCCAGAGCCAGCACTATGGCGCGGAGTACGGTACATCTGTTGATGGGGAGAAACCCGTATTCTACCGGAAACCGTTCGACATGTCTTACCTATCAAATCCGTACATGCAACCGCATTCACAGCAATTTGGTCAACATCCACTTCCGCATCATGCTTCACACTCCAACCACCATCATATGGGGCATATGCAACACCAACAGCATCAGAATCTTCCACCACATACTCCGACAGTGCCATCTAATATGCAGCATTCGCCACAACAACTTCCACCGGAGCATATGCAGCGACCGCAACACTCGCAAAACTTCCACGAGTATTTTGATCATTCGGATCAAAATTCCTCAATCGAACCTTATGCGTACGTGCTTCAAAAGCCCATCGTCCCGATGTTGTCTACGGAAACATCAGCGCCAATGCTTCCTACCTCGTTTTCAACGCCAGAAGTACGATCACCGTACGAGAACGATCATCATGCTGTCGAACCGGTCTACTTTAAGTGTGAAAACTGTCCGGGAATGTTCGAAACAAAGGCGAAGCTTGAGAAACACAGTAAAACGCACCTGTCAAACGGAGGCCAGCATGATTTTAAATGTCGAATGTGTGAAAAAACGTTTCGCACCAGAAGTACGCTTATCTGCCATGAAAAGGTGCACGGCGAGAACGGAgtggacaatagcttttcgtgtgtggagtgcggtaaagtgtttgcaactgccgaaaagctgcaggttcaccggcgtttacacacgggagaaaagccttaccagtgcaaggtgtgcctgaagcactttaaccatcaatcgaatctgatcgtgcactcgcgtatccacgacaaggtaaagaaggcactgaaatgtgctcgctgcagcaaggtgctggataatgaggaacgtttggccatccatatgcgcttgcatacgggcgaaaagccgtacaaatgttcgtactgcgagaaacgtttcaatcacaagagtacggtcagcacgcacGAAAAGGCGGCACACATAGCGGCTAACTCGTTCAAATGTGAACGGTGCCATAAGACGTTCAATCAAAAGTGCCAGCTGCAGTATCACGAGAAGCTGCAAGAGGAACATACGATCGCTTGTGCCCACTGTGAGAAGGTGTTTTGCTACAAGGCCAGTCACAAGGAGCACATGTTTAAGGTGCACTTTCCACGCCCGAAAAAGGAACAAAAGCGGGAAGAGACGAGCGGGAAGACGGACGGTTTAGGGGATGAAGGTGGTGGTGTTGGACCCGGCTCTAGCTCCGGAAATGGTAATCAAGGAAGGAACAAGTTCAAATGTAACGTTTGCGATCGTCGGTTTTATTACAAACGTGCACTGGAAGTGCATATGGGTGTGCATGACGCTTCGCTGGATGTAAACGTACTATACTTTTCGTGCAACTACTGTCCAGAAACATTTACTGAGGAGGAATCGCTACAGAAACATGAAGCTAAGCACGTAGCTGATGGGACGGTTGACTTCCTGCAGAACATGAGGGCACTAGAACAGTCAGAAAATCCAGCCAACGGGCAAGTTGATGGTGGTTTCCGATGTCCGTTATGTTTTAAGCGTTTCGAGGATCAACAGACATTGCGCGATCACCACAAAACGCACCTCTGCTCGTCCCCGGACTGTACCAAGTGTGGACCAGCGCGTGGCGATGAGTTCGATCTGACGCGCAGTACGTACGATGCGAACGATGACATGCGCAAAACGGTATGCAACATTTGCCACCGGCAATTGCCTACATTCGAGCAGTTCCAGAACCATTTCCATTACCATACGTCCCGCGTACCGTTTTACTGTTATCACTGTCGGGAGGAGTTTACCGACAAGCGGGAACTGTACAACCACTCGAGGACGCATGCACCACGCGAACCCGAGTCGTATACGTGCGAGGTATGCGCGAAGGTGTTTTCGACCAAGGGCAATTTTAAGCGGCATTTGAAATCTCACGAAACGGTCCGTGCGTTCGCGTGCGATCGCTGCTCCAAGCAGTACGACTACAAGAGTGCACTGGAGGTGCATCTGAGGCGATCCCACGGTATCGAACTATAG
Protein Sequence: MEYNNVYNKPYCGVISQPIAPTASSGYFPANDTTPTFLKVPNPPYIKQESGTVGSDTVIIGGTITPPVNYSQSQHYGAEYGTSVDGEKPVFYRKPFDMSYLSNPYMQPHSQQFGQHPLPHHASHSNHHHMGHMQHQQHQNLPPHTPTVPSNMQHSPQQLPPEHMQRPQHSQNFHEYFDHSDQNSSIEPYAYVLQKPIVPMLSTETSAPMLPTSFSTPEVRSPYENDHHAVEPVYFKCENCPGMFETKAKLEKHSKTHLSNGGQHDFKCRMCEKTFRTRSTLICHEKVHGENGVDNSFSCVECGKVFATAEKLQVHRRLHTGEKPYQCKVCLKHFNHQSNLIVHSRIHDKVKKALKCARCSKVLDNEERLAIHMRLHTGEKPYKCSYCEKRFNHKSTVSTHEKAAHIAANSFKCERCHKTFNQKCQLQYHEKLQEEHTIACAHCEKVFCYKASHKEHMFKVHFPRPKKEQKREETSGKTDGLGDEGGGVGPGSSSGNGNQGRNKFKCNVCDRRFYYKRALEVHMGVHDASLDVNVLYFSCNYCPETFTEEESLQKHEAKHVADGTVDFLQNMRALEQSENPANGQVDGGFRCPLCFKRFEDQQTLRDHHKTHLCSSPDCTKCGPARGDEFDLTRSTYDANDDMRKTVCNICHRQLPTFEQFQNHFHYHTSRVPFYCYHCREEFTDKRELYNHSRTHAPREPESYTCEVCAKVFSTKGNFKRHLKSHETVRAFACDRCSKQYDYKSALEVHLRRSHGIEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00105287;
90% Identity: -
80% Identity: -