Basic Information

Insect: Anopheles cruzii
Gene Symbol: -
Assembly: GCA_943734635.1
Location: OX030879.1:56236929-56243916[-]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 7.5e-05 0.19 11.6 0.1 21 43 82 104 75 113 0.86

2 11 0.0037 9.6 6.2 0.1 23 47 112 136 109 141 0.83

3 11 0.0053 14 5.7 0.1 23 52 140 169 136 170 0.86

4 11 0.029 76 3.4 0.0 23 49 168 194 165 199 0.85

5 11 0.75 1.9e+03 -1.2 0.0 23 48 196 221 192 226 0.82

6 11 0.77 2e+03 -1.2 0.0 23 48 224 249 215 254 0.82

7 11 0.14 3.7e+02 1.2 0.1 23 52 252 281 248 282 0.86

8 11 0.029 75 3.4 0.0 23 51 280 308 276 310 0.84

9 11 0.04 1e+02 2.9 0.0 21 46 306 330 303 337 0.86

10 11 0.00013 0.33 10.9 0.2 23 45 336 358 334 363 0.91

11 11 3.5 9e+03 -3.3 0.3 33 45 598 610 594 615 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	7.5e-05	0.19	11.6	0.1	21	43	82	104	75	113	0.86
2	11	0.0037	9.6	6.2	0.1	23	47	112	136	109	141	0.83
3	11	0.0053	14	5.7	0.1	23	52	140	169	136	170	0.86
4	11	0.029	76	3.4	0.0	23	49	168	194	165	199	0.85
5	11	0.75	1.9e+03	-1.2	0.0	23	48	196	221	192	226	0.82
6	11	0.77	2e+03	-1.2	0.0	23	48	224	249	215	254	0.82
7	11	0.14	3.7e+02	1.2	0.1	23	52	252	281	248	282	0.86
8	11	0.029	75	3.4	0.0	23	51	280	308	276	310	0.84
9	11	0.04	1e+02	2.9	0.0	21	46	306	330	303	337	0.86
10	11	0.00013	0.33	10.9	0.2	23	45	336	358	334	363	0.91
11	11	3.5	9e+03	-3.3	0.3	33	45	598	610	594	615	0.83

Sequence Information

Coding Sequence: ATGCTTAACCAAGAACAATTGGGTGACAATAAGCACACATTGGCTTTATCACTTACTCTGGGCAATACGCTTTTCAATCTCAACAAAATAAAATGCCCGCAATGCCGGAAGCGTTTCGATTCGGTGGAAGAAATGCAACAACATCAGACTAAGCACCTGACGGAGAACAAGTTTAAATGTGAAATATGTAGTAAAGAGTTCCCCAGCCATAGTTCCATGTGGAAACACACTAAGGCACACACCGGTGAACGACCCTTTGTATGTCCAATATGTAATAAAGGATTCACTCAACTAGCCAACCTTCAACGACATGATCTCGTTCATAATGGACTGAAACCGTTCAAGTGTCCCATTTGTGAAAAGTGTTTTACACAACAAGCAAACATGCTGAAACATCAACTACTTCATACGGGACTTAAACCATACAAATGTCCAGTGTGCCAGAAAGCGTTTTCGCAGCACGCAAACATGGTCAAACATCAAATGCTTCACACAGGTATTAAGCCGTACAAATGTCCAACTTGTGATAAGGCATTTGCACAGCACGCAAACATGATGAAACATCAGATGCTGCACACCGGGTTGAAGCCGTACAAATGTGGCACTTGCGATAAGGCGTTCGCACAACAAGCCAACATGGTCAAACATCAGATGCTGCACACCGGTTTAAAACCGTACAAATGCAATACCTGCGGCAAAGCATTCGCCCAGCAGGCCAACATGGTCAAACACGAGATGCTTCATACGGGAATTAAACCGTACAAGTGTTCGGTGTGCGAAAAAGCCTTCGCCCAGCACGCGAACATGGTCAAACATCAGATGCTTCACAGCGGGATCAAACCGTACAAATGTCCCACCTGCGACAAAGCGTTCGCCCAGCAGGCCAATATGGTTAAGCATCAGATGCTCCATACGGgagaaaaaccattcaaatgcaacagctgtgataaggctttctcgcaacgtgccaatctgaagaagcatgagatggtgcacctgggtatccggccgcacacgtgtccactctgcaccaagtcctactcgcagtattccaacctcaagaagcacctgctcgtgcaccAGAAGCAGGCACTGAAGCAGGAGCAGCAAAATGGTCAAGTGACGGTCGTCCTGTACAATTGCCAAACCTGTAAGATGCAGTTCGAGGACATCATCGAGTTTGTGCGCCACACGAAACAATGTGATATGAATAACACCGTTCAGCACAATGTGAAACTGGAGagcatcaagagcgaggtcgacatcgacggtagttccaattcgggcctccagcaacagcaacaacagcagcagcatattatcgccaacggtggtgttgtagcgctaaacgttagccagcaccagttactagccccttcgccagccccaccggcaccagTCACCAGTCAAATGCATCTTCCGTCGGCCATTCTAACGTCGGTCATTTCATCGTCGATCGGCTCGAACGTGACCGCACACTCGCTGGCGAACTCGGTACACGCAGCGCACGCCGCTAGTCACGTGACCGCCAACGGTGGTATCCTCATCGCGGGCGGATTACccaccgtccatccgcacgcccagcagcagcacactccgcccggtgtgctcacgcagcacacgcacgcacacgtgcaacaggcacatcaacaacagcagcagcaacagcaacagcagcaacagcaacagcagcaacagcaagttattacccatcagcaactttcgcccgtcggcagctctcaccagcagcaggccacacagcagcagcagcagcagcagcaacagcatttggtgctccagcaacagcacaacctgccgatccacctgcagcagcagctgtcgcaccatctgatcaccacccatctgccgcaccacccgggccaggagcatgccggggcgacggccgtcgatctgcaccaccaggtcaacttccaccaTCCGCACATCACACACCTGCCGAATCTGTCACACAAAATCCTGTCGCCGCTGTTCCACATTCCGACGTTCAACAACAACCACAGCACATAA
Protein Sequence: MLNQEQLGDNKHTLALSLTLGNTLFNLNKIKCPQCRKRFDSVEEMQQHQTKHLTENKFKCEICSKEFPSHSSMWKHTKAHTGERPFVCPICNKGFTQLANLQRHDLVHNGLKPFKCPICEKCFTQQANMLKHQLLHTGLKPYKCPVCQKAFSQHANMVKHQMLHTGIKPYKCPTCDKAFAQHANMMKHQMLHTGLKPYKCGTCDKAFAQQANMVKHQMLHTGLKPYKCNTCGKAFAQQANMVKHEMLHTGIKPYKCSVCEKAFAQHANMVKHQMLHSGIKPYKCPTCDKAFAQQANMVKHQMLHTGEKPFKCNSCDKAFSQRANLKKHEMVHLGIRPHTCPLCTKSYSQYSNLKKHLLVHQKQALKQEQQNGQVTVVLYNCQTCKMQFEDIIEFVRHTKQCDMNNTVQHNVKLESIKSEVDIDGSSNSGLQQQQQQQQHIIANGGVVALNVSQHQLLAPSPAPPAPVTSQMHLPSAILTSVISSSIGSNVTAHSLANSVHAAHAASHVTANGGILIAGGLPTVHPHAQQQHTPPGVLTQHTHAHVQQAHQQQQQQQQQQQQQQQQQQVITHQQLSPVGSSHQQQATQQQQQQQQQHLVLQQQHNLPIHLQQQLSHHLITTHLPHHPGQEHAGATAVDLHHQVNFHHPHITHLPNLSHKILSPLFHIPTFNNNHST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00097215;
90% Identity: iTF_00097215;
80% Identity: iTF_00097215;