Acru011555.1
Basic Information
- Insect
- Anopheles cruzii
- Gene Symbol
- -
- Assembly
- GCA_943734635.1
- Location
- OX030880.1:68424515-68427481[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.027 1.7 9.1 1.5 2 23 210 232 209 232 0.92 2 15 0.0011 0.069 13.5 0.2 2 20 245 263 245 264 0.95 3 15 0.0013 0.077 13.3 0.3 1 23 277 299 277 299 0.98 4 15 0.077 4.7 7.7 2.9 1 13 482 494 482 503 0.82 5 15 0.00035 0.022 15.0 0.4 2 23 559 581 558 581 0.95 6 15 8.9e-05 0.0054 16.9 0.1 3 20 599 616 597 618 0.93 7 15 0.0036 0.22 11.9 1.5 1 23 683 707 683 707 0.92 8 15 0.002 0.12 12.7 0.1 2 20 738 756 737 758 0.94 9 15 0.74 45 4.6 1.0 2 23 765 786 764 786 0.95 10 15 0.00017 0.01 16.0 3.9 1 21 792 812 792 814 0.95 11 15 4.9e-05 0.003 17.8 0.3 2 23 820 842 819 842 0.94 12 15 6.4e-06 0.00039 20.5 3.9 1 23 847 869 847 869 0.98 13 15 0.86 52 4.4 0.5 1 23 875 900 875 900 0.95 14 15 5.7e-05 0.0034 17.5 2.3 1 23 906 928 906 928 0.98 15 15 0.00036 0.022 15.0 0.1 1 21 934 954 934 955 0.96
Sequence Information
- Coding Sequence
- ATGGAAATGCAAGTTCTTGCTTCTGGTGGTAAAAACGATCAATTTTCAATCCTTTGGGGTGGTGGTGGTTTGGGTTTAGTGGATGGAAGCAATGTATTTAAGACTGTCCGCAAAGTCTGTCGGATATGCAACAATCCGGACGACGACGATCTCATCTCGGTGCAGCTCGTCCAGGAACAGATATCGATCGCCGAAAAGATCGAGGCGATCACAGGCATCCAGGTGACCAGTGATCGGCGATTGCCACAAAACATTTGCTTAGATTGCCTCGAGCGGCTACGGCTGGCGTTCGAGCTGCGCCAACAGTGCATTGAAACGGACGCCCGGTTACGCGCATCACTCGACGCAACACAAACGCCAACCGAAGAGTATTATGTGGAAACACTCGAAGAAGAAGCCGAAGAGCAAATGGGGTGCACCGAGCAGGAGCTCCCTTGGGAAGTGGAAGAGATTTTCGAGAAGCACAGTACGGAACTGGAGATCAACGAGGATCTTTCAAAGCGAGAGTCATGCAACGACCCACAGCCAACCGTTGCATTATCAGAAACTGCAGAATGCCCCACCACAAAGCAAAGCGCTCCATGGCGCGAAGACGTTCACTACGTCCAGGTGGATTCCGAGTTCATTCCATGCTGCGGCTGCACCATGACTTTCGAAAGCGAAGACGACCTACAGGTACATTCCATCCGTTGCCATCGGAGCCGGCAGCAGTGCTCGAAGTATCCGCCGGAGCAATGCACCGTCTGCTATCAGACGTTCACGAGCGCAAAAGCACTGGAACGCCACCGGGCGGACGCGGACGGGCAGCGAAAAGAAACCTCCCTGCAGTACCAGTGCCTCATTTGCAACAGTCTCTTCACTCAGCAAGCGGAGCTGTTCGATCATCTTGAGTCTCATGTAGCGGAGGTCTCGTCGATGGAGACGAATGACAAAGTGAGTGAAATCCGGATCGAGTTGCAGTCACCGCCGCCGGGGCAAACGATGGAAGACGATGGGGACCGGATAGATGAGGACAGTGTGGCCGAAACGTTAGGTGAAGTGTACTCAATCGAGTTCGCGCCGGACGACGAATCGTCCCAGACCGAAGAATACATCGAGGTGGACGCGAAGGAAGAAGATGACGAACACGACGATGGCGAGTACGGTGACGAGGAGGACACAGATCGCGACAAGACACGGGTGGCAAAACAGGGGCCAAATTGGCAGCAGTCCAAAACGCTGCTGCGGAAAGAAATGTATCAAATACCGGAAAAGTATCTGCGGATCGTATCGAAGAAGGATGGCTATATGATCGTAGAGTTAAAGCAGCACCGGTGCTGCTGCTGTGCCCAGTTTTTCGAAACTACTCACCAACTCGAGCAGCATCTCAAGAAGCGCAACAAACGCCAGCAGCAAACGACGCCCAAAGAGCCGAAAGAGGATTCGTCGTCCACTAGTCATCGATACACCTGCGAGTACTGCGGGAAACAGTTCAAGTTCCCGGTCGTTTACCATTGCCACTTGCGCATGCGGCGGCAACGGCAGTTCTACTTCTGCACGCTCTGCAAAACCGCGATGGAGAGCGAAAAGCGTATGCTGTCGCATATGGTGCACACGCAAAAGCACGCTGCGCACTTTAACCTACCGTATGAGAATATTGAAGATCGCTACTACTCCGTCAAAATGCCCGGTGTGCGGTGCTGCGGATGCGGGCAGCAGTTTACCGACGAGGAGGAGCTCACTGACCACGTCCGTGCGTCGCATCCACCTGAAGCGAGCGATCCCAAACGATCGAGGCGTACGCATCCCTTCGGATGCGATGTGTGTGGCCGTCGTTTCTCTCGCCAATCGCAGCTCGATAATCATACGGCCATGGGAATGGTAGACACACCGACGGGCGCTCGGACGCGCACTGTCTTGCAGTACTACTGCAAGTTGTGCTCGTTCGATACCGCATACCATCGGCGAATGGAGCTTCACCAGCGCAGTGCGATCCACAGCCAGGTCCTGTCGACGATGCGCCTTTGTCCGCTTCAAAACAGTGCCATAAAGTTCGACCGGCTGCGCTATTGTTGCTTCGAGCAGTGCAAGAAGTCCTTCACGGATCTCGTTGAGCTGTATGAACACGTTCGCGACATCCACTCGGAAGCGCTGGCCAAAAACAAACGCACCGTACCCGAGCAGGAAGAAGAGAACGCCGCCACAAAAGCCGGAAGCGGCGCGGGTATGGTCGAGTGTGATGTTTGCGGTTTGCGGCTGAAGCACCAGACGGCGCTCAAAAGGCACCAAGCGTTGCAGGGCCCGCAGGATTGCGTTTGCTCGGTCTGTGGCGTCAAGAAGCGATCCCGCACCGTGCTGCTGGCAcacgagcggacacacaccggggagcggccttactcgtgcgatgagtgcgacaaaacgttctcctcgttcacggcgctccgctcgcacCAAAAGTGTCACCAGCCGCGCAAGCTAGAGTGCGACGTGTGCCAGGAACGGTTTGCACGGCTGGAAAATCTGAAACGCCACGTACAGCTCAAGCACggcgaagcgacgcaccagtgccagtcgtgcccgaagaagtttaaaacgcgcgatacactcaacatccatttgcggacgcacacgggcgagaagccgtacaagtgccggacggagggctgcgacaagtggtacgtgaacgtgtcggaccgacggcggcacgagatgtcgagccacacgatggagcggccacacaaatgtagctactgcgagactgcgttcatccggaagcgccagttggcgattcacgagcggcgtcacacgggcgagcggccgtacgtatgttccgagtgtggcaaggccttTTTGGAATCGGGGCTCCTGCGAAAGCACATCCGAAATGTCTGCCCGAATGCCGCGAGCGATGGAACGGTTGCGCCAGGATAA
- Protein Sequence
- MEMQVLASGGKNDQFSILWGGGGLGLVDGSNVFKTVRKVCRICNNPDDDDLISVQLVQEQISIAEKIEAITGIQVTSDRRLPQNICLDCLERLRLAFELRQQCIETDARLRASLDATQTPTEEYYVETLEEEAEEQMGCTEQELPWEVEEIFEKHSTELEINEDLSKRESCNDPQPTVALSETAECPTTKQSAPWREDVHYVQVDSEFIPCCGCTMTFESEDDLQVHSIRCHRSRQQCSKYPPEQCTVCYQTFTSAKALERHRADADGQRKETSLQYQCLICNSLFTQQAELFDHLESHVAEVSSMETNDKVSEIRIELQSPPPGQTMEDDGDRIDEDSVAETLGEVYSIEFAPDDESSQTEEYIEVDAKEEDDEHDDGEYGDEEDTDRDKTRVAKQGPNWQQSKTLLRKEMYQIPEKYLRIVSKKDGYMIVELKQHRCCCCAQFFETTHQLEQHLKKRNKRQQQTTPKEPKEDSSSTSHRYTCEYCGKQFKFPVVYHCHLRMRRQRQFYFCTLCKTAMESEKRMLSHMVHTQKHAAHFNLPYENIEDRYYSVKMPGVRCCGCGQQFTDEEELTDHVRASHPPEASDPKRSRRTHPFGCDVCGRRFSRQSQLDNHTAMGMVDTPTGARTRTVLQYYCKLCSFDTAYHRRMELHQRSAIHSQVLSTMRLCPLQNSAIKFDRLRYCCFEQCKKSFTDLVELYEHVRDIHSEALAKNKRTVPEQEEENAATKAGSGAGMVECDVCGLRLKHQTALKRHQALQGPQDCVCSVCGVKKRSRTVLLAHERTHTGERPYSCDECDKTFSSFTALRSHQKCHQPRKLECDVCQERFARLENLKRHVQLKHGEATHQCQSCPKKFKTRDTLNIHLRTHTGEKPYKCRTEGCDKWYVNVSDRRRHEMSSHTMERPHKCSYCETAFIRKRQLAIHERRHTGERPYVCSECGKAFLESGLLRKHIRNVCPNAASDGTVAPG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00094669;
- 90% Identity
- -
- 80% Identity
- -