Basic Information

Insect: Anopheles bellator
Gene Symbol: aop
Assembly: GCA_943735745.2
Location: OX030928.2:79120348-79125157[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.016 0.94 9.8 2.6 1 23 416 439 416 439 0.94

2 16 0.0014 0.08 13.1 0.3 2 20 452 470 451 471 0.95

3 16 0.46 27 5.2 0.6 1 23 482 504 482 504 0.97

4 16 0.092 5.3 7.4 2.9 1 13 684 696 684 705 0.82

5 16 3.1e-05 0.0018 18.3 0.6 2 23 761 783 760 783 0.95

6 16 0.00014 0.0079 16.3 0.1 3 20 798 815 796 817 0.93

7 16 2.8 1.6e+02 2.7 0.9 1 23 834 858 834 858 0.91

8 16 0.0071 0.41 10.9 3.8 1 23 882 906 882 906 0.93

9 16 0.017 0.96 9.8 0.2 3 20 931 948 930 950 0.94

10 16 0.62 36 4.8 0.6 2 23 957 978 956 978 0.95

11 16 0.00014 0.008 16.3 3.4 1 21 984 1004 984 1006 0.95

12 16 0.00045 0.026 14.7 0.2 2 23 1012 1034 1011 1034 0.94

13 16 1.8e-05 0.001 19.1 3.4 1 23 1039 1061 1039 1061 0.98

14 16 3.6 2.1e+02 2.4 0.5 1 23 1067 1092 1067 1092 0.95

15 16 3.3e-05 0.0019 18.3 1.5 1 23 1098 1120 1098 1120 0.98

16 16 0.01 0.58 10.4 0.0 1 22 1126 1147 1126 1147 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.016	0.94	9.8	2.6	1	23	416	439	416	439	0.94
2	16	0.0014	0.08	13.1	0.3	2	20	452	470	451	471	0.95
3	16	0.46	27	5.2	0.6	1	23	482	504	482	504	0.97
4	16	0.092	5.3	7.4	2.9	1	13	684	696	684	705	0.82
5	16	3.1e-05	0.0018	18.3	0.6	2	23	761	783	760	783	0.95
6	16	0.00014	0.0079	16.3	0.1	3	20	798	815	796	817	0.93
7	16	2.8	1.6e+02	2.7	0.9	1	23	834	858	834	858	0.91
8	16	0.0071	0.41	10.9	3.8	1	23	882	906	882	906	0.93
9	16	0.017	0.96	9.8	0.2	3	20	931	948	930	950	0.94
10	16	0.62	36	4.8	0.6	2	23	957	978	956	978	0.95
11	16	0.00014	0.008	16.3	3.4	1	21	984	1004	984	1006	0.95
12	16	0.00045	0.026	14.7	0.2	2	23	1012	1034	1011	1034	0.94
13	16	1.8e-05	0.001	19.1	3.4	1	23	1039	1061	1039	1061	0.98
14	16	3.6	2.1e+02	2.4	0.5	1	23	1067	1092	1067	1092	0.95
15	16	3.3e-05	0.0019	18.3	1.5	1	23	1098	1120	1098	1120	0.98
16	16	0.01	0.58	10.4	0.0	1	22	1126	1147	1126	1147	0.95

Sequence Information

Coding Sequence: ATGAAGCTGCTACCGATCCCACTGTCGCCGCTGAatgcgccgccaccgctcggGCTGTGGAACTCGGAGCTCCTGTGGCGCTACCCGCCCGCTCCGCCGAGCCCGCTGGCCGACCTGAAGACgcagctgccgccgcagcTCAACACGGACCCGCGCATCTGGGGCCGGGACGAGGTGGTCGTGTTTCTGCGGTTCTGCGAGCGCGAGTTCGACCTGCCCAAGTTCGACCTGGACCTGTTCCAGATGAACGGCAAGGCGCTGTGCGTGCTGACCAAGAACGATCTCGCCGAGCGCAGCCCGGGCGCGGGCGACGTGCTCCACAACGTGCTGCAGATGCTGATCCGCGACGCGCAAACCCTGCACCGGCACCTCCCGAGCAGCCCGGTCACGCCGACCGGCCGCTACCCGCTGTCGCCCCACAGCCACCCGCCGACCCCGAACTGGAGTGCCCTGGCCCCGCCCGACAGCCCGTTCTTCCACAGCTCGCACCTGCAGCAGTTCATGGCCGCGTCCAACTCGGTCACCCTCAGCCCGGCCCCCTCGATCGACTCGCAGGCCGGAAGCCCCCCGTCGCAGGGCCACGGCGAGGCGACCGTCTTCCAGAagtcctcctcgtcgtccgtcTCGTCGACGGCCTCGTCaagcggcggtggcagtagcggcggcggcggcggcggaggtcctggaagcagcaacggcaacgGAAGCAATGTGTTTAAGACTGTCCGTAAAGTCTGTCGAATATGCAACAatccggacgacgacgatctcATCTCGGTGCAGCTGGTTCAGGAACAGGTATCGATCGCTGAAAAGATTGAGGCGATCACGGGCATCGAGGTGACCAGTGATCGCCGTTTGCCACAAAACATTTGCTTGGATTGCTTCGAGCGGCTACGGCTGGCGTTTGAGCTGCGCCAACAGTGCATTGAAACGGACGCCCGGTTACGCGCATTACTCGAAGCAACACGAACGCCAACCGAAGAGTATTATGTGGAAACACTCGAAGAGGAATGCGAAGAGCAAACGGGGTGTACCGAGCAGGAACTCGCCTGGGAAGTGGAAGAGATTTTCGAGAAGCACAAGACGGAACTGGTGGTCGACGACGATCTTGAAAAACAAGAGTCATGCAACGAACCCCAGGAAGCCGTTCCATTGCCAGAAACCGCACAATCCGAATCCACCTCAAAGCAAAGCGCTTCATGGCGCGAAGACGTTCACTACGTTCTGGTGGGTCTCGATTGCTTCCCCTGCTGCGGCTGCACCATGACTTTCGAAAGCGAGGACGACCTAAAGGTACATTCCATTCgttgccaccggaaacggcagcAGCGCTCGAAGTACCTTCCCGTGCAATGCAGCGTCTGCTATCAGTCGTTTACCAGCGCAAAGGCACTGGAACGCCACCACGCGGACgggcagcgaaaagaaacCTCCCCGCAGTACCAGTGCCTCAGTTGCACCAGTCTCTTCACTGAGCAAGCGAAGTTGTTCGATCATCTCGAGTCTCATGCAGCAGAGGTCCCGTCGATGGTGATGAATGACAAACTGAGTGAAATCCGGATCGAGTTgcagtcgccgccgccggggcaAGCAATGGAAGATGGTGGGGACAGGATAGACGAGGGCAGTGTGGCCGACGCGTTGGATGAAGTGTATTCCATCGTGTTCATGCCGGACGATGAATCGTCCGAACCTGAAGAATACGTCGAGGTAGACGGTAAGGAAGCAGATGACGAATACGAGGATCGCGAactcgacgacgaggaggaaacAAATAGCGTCGCTAATCGCAAGACTGTGCCAAAACAAGGGTCACACTGGGAGCATACCAAATCGCTGCTGCGCAAAGAAATGTACAAAATACAGGAAAAGTACCTGCGGATCGTAGCGAAGCAGGATGGCTATATGATCGTAGAGTTAAAGCAgcaccgttgctgctgctgtgcccaGTTTTTCGAAACTACCCACCAACTCGAGCAACATCTCAAGAACAAACGCCAGCGGAAAACGACGCGACAGCAGAAAAAGGATTCGTCGTCCACTCCGTACACCTGCGAGTACTGTGGGAAACAGTTCAAGTTCCCGGTGGTTTACCATTGCCACCTGCGCAtgcggcagcaacggcagttCTACTTCTGCACGCTCTGCAAAACCGTGATGGAGAGTGAAAAGCGCATGCTCTCGCATATGGTGCACACGCAGAAACACGCTGCGTACTTTAACCTACCGTATGAGGATATTGATGATCGCTACTACTCCGTCCAAATGCCCGGTGTGCGGTGCTGCGGTTGCGGGAAGCAGTTCAAGGACGAGGAAGAGCTCACTGACCACATCCGTGCGTCGCACCCGCCGGAAGCGAGCGATCGAAAACGCACGCATCCCTACGGATGCGATGTATGTGGCCGTCGTTTCATTCGCCAATCGCAGCTCGTTAATCATACGGCCATGGGAACGGTAGACACACCGACGGGCGCTAGGATGCGCCCTGTCTTGCAGCACTACTGCAAGTTGTGCTCGTTCGAAACCCCAAACGCGCGTCGAATGGAGCTTCACCAGCGCAGTGCGATCCACAGTCAGGTCCTCTCGTCGATGCGTCTCTGTCCGCTTGAAAACAGCGCCATAAAGCTCGACCCGGTGCGCTACTGTTGCTTCGAGCAGTGCAAGAAGTCCTTCACGGATCTCATCGAGCTGTGTGCGCACGTTCGCGGGTTCCACTCGGAGgcgttggccaaaaacaaacgcatcGCACGCGAGCAGGATGAAGAGAGCGGCGCGGGTACGGTCGCGTGTGATGTTTGCGGTCTGCGGCTGAAACATCTGACCGCGCTCAAAAGACACCAATCGTTGCGTGGCGCGCAGGTTTGTGTCTGCTCGGTCTGTGGCATCAAAAAGCGGTCCCGcgccgtgctgctggtgcacgAGCGGACACACACCGGGGAACGACCGTATTCCTGCGATGAATGCGACAAATCCTTCTCCTCGATCACGTCGCTGCGCTCACACCAAAAGTGTCACAAGCCACGCGAGCTGGAGTGCGACGTGTGCCTGGAACGGTTTGCGCGGCTGGAAAATCTGAAACGCCACGTACAGCTGAAGCACGGCGAAGCGACGCACCAGTGCCAGTCGTGCCCGAAGAAATTTAAAACGCGCGACACTCTCGCCATGCATCTGCGAACGCACACCGGCGAGAAGCCGTACAAATGCCGGACGGAGGGCTGCGAAAAGTGGTACGTCAACGTgtccgaccgacggcggcacgAGATGTCGAACCACACGATGGAGCGGCCGCACAAATGTAGCTACTGCGACGCTGCGTTCATCCGGAAGCGCCAGTTGGCCATTCACGAGCGGCGCCACACGGGAGAACGGCCGTTCGTATGTTCCGACTGTGGCAAGGGCTTTTTGGACGCGGTGATCCTGCGCAAGCACATCAGAACTGTCTGCCCGAACGCCGCGAGCGATGGAACTGTTGCGCCAGGATAA
Protein Sequence: MKLLPIPLSPLNAPPPLGLWNSELLWRYPPAPPSPLADLKTQLPPQLNTDPRIWGRDEVVVFLRFCEREFDLPKFDLDLFQMNGKALCVLTKNDLAERSPGAGDVLHNVLQMLIRDAQTLHRHLPSSPVTPTGRYPLSPHSHPPTPNWSALAPPDSPFFHSSHLQQFMAASNSVTLSPAPSIDSQAGSPPSQGHGEATVFQKSSSSSVSSTASSSGGGSSGGGGGGGPGSSNGNGSNVFKTVRKVCRICNNPDDDDLISVQLVQEQVSIAEKIEAITGIEVTSDRRLPQNICLDCFERLRLAFELRQQCIETDARLRALLEATRTPTEEYYVETLEEECEEQTGCTEQELAWEVEEIFEKHKTELVVDDDLEKQESCNEPQEAVPLPETAQSESTSKQSASWREDVHYVLVGLDCFPCCGCTMTFESEDDLKVHSIRCHRKRQQRSKYLPVQCSVCYQSFTSAKALERHHADGQRKETSPQYQCLSCTSLFTEQAKLFDHLESHAAEVPSMVMNDKLSEIRIELQSPPPGQAMEDGGDRIDEGSVADALDEVYSIVFMPDDESSEPEEYVEVDGKEADDEYEDRELDDEEETNSVANRKTVPKQGSHWEHTKSLLRKEMYKIQEKYLRIVAKQDGYMIVELKQHRCCCCAQFFETTHQLEQHLKNKRQRKTTRQQKKDSSSTPYTCEYCGKQFKFPVVYHCHLRMRQQRQFYFCTLCKTVMESEKRMLSHMVHTQKHAAYFNLPYEDIDDRYYSVQMPGVRCCGCGKQFKDEEELTDHIRASHPPEASDRKRTHPYGCDVCGRRFIRQSQLVNHTAMGTVDTPTGARMRPVLQHYCKLCSFETPNARRMELHQRSAIHSQVLSSMRLCPLENSAIKLDPVRYCCFEQCKKSFTDLIELCAHVRGFHSEALAKNKRIAREQDEESGAGTVACDVCGLRLKHLTALKRHQSLRGAQVCVCSVCGIKKRSRAVLLVHERTHTGERPYSCDECDKSFSSITSLRSHQKCHKPRELECDVCLERFARLENLKRHVQLKHGEATHQCQSCPKKFKTRDTLAMHLRTHTGEKPYKCRTEGCEKWYVNVSDRRRHEMSNHTMERPHKCSYCDAAFIRKRQLAIHERRHTGERPFVCSDCGKGFLDAVILRKHIRTVCPNAASDGTVAPG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00097242;
90% Identity: -
80% Identity: -