Acru002255.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles cruzii
Gene Symbol
-
Assembly
GCA_943734635.1
Location
OX030879.1:5412865-5417461[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 8.2e-06 0.0005 20.2 2.1 1 23 181 203 181 203 0.99
2 15 0.056 3.4 8.1 0.5 1 23 209 232 209 232 0.98
3 15 0.00042 0.025 14.8 0.5 3 23 254 275 253 275 0.94
4 15 0.038 2.3 8.6 3.0 1 23 281 304 281 304 0.91
5 15 1.4e-05 0.00086 19.4 0.1 1 23 502 524 502 524 0.98
6 15 0.00016 0.0096 16.1 0.3 1 23 530 552 530 552 0.99
7 15 0.013 0.77 10.1 2.5 1 23 658 680 658 680 0.98
8 15 1.4e-06 8.5e-05 22.6 0.9 1 23 686 708 686 708 0.99
9 15 2.1e-05 0.0013 18.9 0.3 1 23 817 839 817 839 0.95
10 15 0.0012 0.076 13.3 3.4 1 22 845 866 845 869 0.90
11 15 1.4e-06 8.5e-05 22.6 0.8 1 23 1039 1061 1039 1061 0.99
12 15 8e-07 4.9e-05 23.4 1.8 1 23 1067 1089 1067 1089 0.99
13 15 0.00026 0.016 15.5 0.8 1 23 1343 1365 1343 1365 0.98
14 15 3.6e-06 0.00022 21.3 2.9 1 23 1371 1393 1371 1393 0.99
15 15 0.0035 0.21 11.9 0.5 2 23 1400 1422 1399 1422 0.96

Sequence Information

Coding Sequence
ATGAACCAGACCGCGAACAGCATGGAACTGAAGGCGGAACGGCGCGAAACCGGGGAGCCAGAGGAGGACGACGACGGTCAGCCTTCGTCGAGCGCCAACGATGGTGGTGGCAATTCGGACCAGGAGATAGTGGTCGGCATCGACGAGGATCACATCAAGTTTCTCACCAGCATGCATTCGGGCGATGAGGAGCCCTCCAACGGGCACCCCGCACTGGCGGTAAATGGTGGTGGTGGTGGTGGGGCCGGAACTGCGGGCAAACTCGCCCACCGCAAACAACAGCAACATCAACAGCAGCTGCAGCATCATTCCGTTCGATTGAATGGCATTTTCAACGGAAGAAATGGTAAAGCACAGCCAACTGCGTTCGGAAACGGTAGCAGAGCATCGAACCTTGCGTTTAGCGAGGATTCGGATGACGATGACAGTGATGATGACGAGATGGCGGACTCATCATCAGATGACGATGAGGACGTGATGGCGACGGCGGCCTCGATCCTCTCGAAAACGGCTCAGCGATCGTCGGATTACACTCGCCGGTATCGGTGCGACCTGTGTCCAAGGGCCTTCCACCGGCCGGACTTTCTGCAGTACCATATGCGGACGCACGAGAAGAGCAATTCGTTCGAGTGTAAGCTTTGCTTCAGCATCTTCGCGTCGGATCCGGCGTTCGCCCATCACATCCGCACCGAGCACGCCGGGATGGGGTTGGCCGATGCGCTGCCGCCGGTACCGGAGTCCGAGGCCCGTTTTGCCGCGTGCACGTACTGTGACAAAACGTTCGCCGATGGCGATCAGCTGGAGGATCACCTCCACCAGCAGCATCTCGGGATGCGACCGTTCAAGTGCAACATGTGCCCGAAAGCCTTCATCCGGATGGATTTTCTGCAGTGCCATTACGCCAAGTATCACAACTTTCACCGGTTCGGTGTGATCGGTGCAGGAGCCAACGGAGGAATGGGTGGTGGCGGAGGAGGATTGTACTCCGGTACGTTTGATCCGATCGAAAGTGTTGTGCAGCGCGCAGCGATGACGATGGGAGGCCACGCTGGTGCTGCTGCTGGTGGTGGCCTTGGTGACGGTCACGGCGGAGGCGGTGACCAAGGTGCATCGTTCCAGGCGGCCGGCCAGCCACGGTTGTCGGTACGGAAAATGGAAGATTTGCTCGACGGACACGGTGGCATGGCCGGAGGGCGCCGTTTGATGCTGGCCGTGGCCGGCGCAGATTATTCGCGCCGAACGTCACACACGGGCACCACGCTCGGTAGCAGTTCGAGTGAGGAGGACGACGATGACGACGAGGAACTGATGGTGTTGGGCGACGATGACGTTGCAATGGGCGGTGCGGTGAGTCACGATAACCGGAAACGAAAAGCCGGCCCAACGCTAACAAACGGTGGCAAAGCGCGCCCAGCGACAAAGAAGAAGCCAACGGTCGGGCTGGTGGCCAAGGCTGGAGTGCCGGCGGTTGTTACGGTCCTGCCTCCGGAGGAAGTGGGTAAATTTCGGTGCCCAGTTTGCGAGCGACGCTTTGTCCGCGAGCCGGAACTCATGGCTCACGTGCGCGTTCACCCGGATCTGCCCACTTACAAGTGTCCGCTGTGTGAACTAACCTTTATTGGATCGGACTACCTGAAGGGTCACCTGAAGAAGCACGTCGTTGGTGATGGTGAAGATCCGGACGCGCCCGGTGCGATCGACATGAAAACATTGAACGAAGGAACTGCTGCTGCACCGGGCCTTTCATCGCCTCCGTCTTCCACACTCACCGCAAACCGTCCATCTTCTACCGTCTCCGCGTCGGGTGCCAGTAAGTTGCCATCGAAACACCCATCGAAACCACCGTCCACGGGCATCTCTCTGTTGAAACCGATCGAAGAGCGGAAAccacccgacagccaacagcagcagcagcagcagcatcatcatcagcaaccccacgagtactgcatcaaaacggccgatggcaagtttatgtgcaccgtgtgcgagcggctcttttcccaccaacaaacggtgcgcatccactttcgcatccacaccaacgaaaagccgtacaagtgtacgttctgtggcgaatcctacatacgatcggactatctcgagcgccacctgaaggtacactttaaggacggTGTTCTTCCGGCTGCCGCGATCGCCAGTATGGCAGCGGCCGCTGCTCGAGATGTGGCGGCGGCCGTCGCGAATGGACGAGCGGCACCGCAGCCAACAGCTTCTTCAACCCCTCCACCGCCAGCGCTGGTTGCGCCGAAGGAAGAATTCATCCACGAAAGCACGACGACGACGACGACGACGACGACGATCACCACCGGTACGAAAACTCCCACCCCGGGCGCAGGTCCGACGACATCCACACCGAAACCGCTGATTGGCAGGGCCGGCTTGGCACCGGAAAACTATCACTTTGCCGAGTCGAAcgatggacagtttgtgtgcaagatctgcgacaaagtgttcgcccacgtggcctcactgcggaagcatgcgctggcccacacggaggagaaaccgtttcactgcgacatttgcgatcgttcgttcaatcgggtcgactatctgaaggaacactttaaatcgAAACGCCACTTGCAGCTGGTGGCGGAAGCGGCCGGGGGAAGCGTTGAGAGGACCGTCGAGGAAGAGGAGGATGATTCGACGATGGATGATAGTGGGCCACCGATAACGCCGGTCATCTCGGTGAAGCgtcacagcagcaacaaagcaaagggtacaaatcgggggaaaccgaagattgacaataaactgaacgagatgcccaatagcgatgccgatggtgtggcggcggcggtacttccgatagcggccagcagttgtggaaacagtcggagcagcaacagtagcagtagtagcaacagttccagcagcagcagcagcagcagcaacagtaatagcagcagcagtagcagtagcggcagtggtgacgccacgccgggaacgaaatccattgccaacaactcttccgggggcggcggcgatggtgatgatgccggccgcgaaagtaacgggggttccgtcggctcgacgcttaatgaattccatCGGTCCGATTAcgagcggacgagcgacgggcgctaccagtgcaaccggtgtgataaaacgttcgttacggcggtcacactcaagatgcacatccggctgcacacgggcgaaaaaccgtacaaatgtgacaagtgcgacaaggcgttcatcagatcggactacttgaagacgcacgaaaagacgcaccgccagcagtcgttcCTTAGTCTGCTAGCCTTAACCTCGAAGGAACCGAGTACGGCATCGGAAGCTGGCGAGGATTCCGAAGACGGGCACGTTAACGGTCGGAACGAAGTGAGTAGATCATCGACGGTGATGAGCAACGGACCACCACAGGAGGCTATGGGAAATATGTCCGATATTTTGAAGGATTCGATGGTTGGGAGAAAAGGTGGACCGAGTGTGGAGGACGACGAGGAACCGGAAGAAGACGAGTCCGGCGAGGAAGAGGATGAATCGGAGGACAGTGAAGAAGAGGAACAGGAGGTTATCAAAGTAACGGTCAAGGATGCAAGTTGCTCGGAGAGTGAAGAAGAAGATGACGATGAAGACGAAAATGATAATTTGGGCGAGGAGGAGGAGGAAGCTGAGGAAGAAGAACTTGATGGCGATGACCACCATGGGGAGCGGCAGAAGTTCGGTGTCGACGGTAACAGCGGAAGTGCCAATCGTGGGACTGGACTATCGTTGCTGCAGTCGAAGAAAGGAGGCACCAAGTTGGAGCAACAAAGTGATCATGGTTTCCATAGCAACCACAGTCACCTCAGCGACATTGGTGAAAGTAGTAACAACGGATACGATGATCACGAGGACGATAGTATGTCACAGGCGAGCGGTGGTACGGCGGGAGGCGGCTCTTcgtacggccattaccaccatccggacgatatgcacctggcgaatggtggcggagtgttggggagtgatggtgatcagagaggcaaacaccgttgcccgatgtgcgacaaactgtttgcgtggccaaagtcgctgaaaatccatctgcgaacgcacacgggcgagaagccgtaccggtgcgacctgtgtggcaagtgtttcgggcggtccgacagtttacgcggccacaagcgaacgcatgccgacgaacggctcgttcagtgccatttgtgtgacgtgagctgcccaagtgcgacggaactggtgcaacatcagctcgtggtgcacaacattcagcCGTTGGAGTGTTAG
Protein Sequence
MNQTANSMELKAERRETGEPEEDDDGQPSSSANDGGGNSDQEIVVGIDEDHIKFLTSMHSGDEEPSNGHPALAVNGGGGGGAGTAGKLAHRKQQQHQQQLQHHSVRLNGIFNGRNGKAQPTAFGNGSRASNLAFSEDSDDDDSDDDEMADSSSDDDEDVMATAASILSKTAQRSSDYTRRYRCDLCPRAFHRPDFLQYHMRTHEKSNSFECKLCFSIFASDPAFAHHIRTEHAGMGLADALPPVPESEARFAACTYCDKTFADGDQLEDHLHQQHLGMRPFKCNMCPKAFIRMDFLQCHYAKYHNFHRFGVIGAGANGGMGGGGGGLYSGTFDPIESVVQRAAMTMGGHAGAAAGGGLGDGHGGGGDQGASFQAAGQPRLSVRKMEDLLDGHGGMAGGRRLMLAVAGADYSRRTSHTGTTLGSSSSEEDDDDDEELMVLGDDDVAMGGAVSHDNRKRKAGPTLTNGGKARPATKKKPTVGLVAKAGVPAVVTVLPPEEVGKFRCPVCERRFVREPELMAHVRVHPDLPTYKCPLCELTFIGSDYLKGHLKKHVVGDGEDPDAPGAIDMKTLNEGTAAAPGLSSPPSSTLTANRPSSTVSASGASKLPSKHPSKPPSTGISLLKPIEERKPPDSQQQQQQQHHHQQPHEYCIKTADGKFMCTVCERLFSHQQTVRIHFRIHTNEKPYKCTFCGESYIRSDYLERHLKVHFKDGVLPAAAIASMAAAAARDVAAAVANGRAAPQPTASSTPPPPALVAPKEEFIHESTTTTTTTTTITTGTKTPTPGAGPTTSTPKPLIGRAGLAPENYHFAESNDGQFVCKICDKVFAHVASLRKHALAHTEEKPFHCDICDRSFNRVDYLKEHFKSKRHLQLVAEAAGGSVERTVEEEEDDSTMDDSGPPITPVISVKRHSSNKAKGTNRGKPKIDNKLNEMPNSDADGVAAAVLPIAASSCGNSRSSNSSSSSNSSSSSSSSSNSNSSSSSSSGSGDATPGTKSIANNSSGGGGDGDDAGRESNGGSVGSTLNEFHRSDYERTSDGRYQCNRCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKTHRQQSFLSLLALTSKEPSTASEAGEDSEDGHVNGRNEVSRSSTVMSNGPPQEAMGNMSDILKDSMVGRKGGPSVEDDEEPEEDESGEEEDESEDSEEEEQEVIKVTVKDASCSESEEEDDDEDENDNLGEEEEEAEEEELDGDDHHGERQKFGVDGNSGSANRGTGLSLLQSKKGGTKLEQQSDHGFHSNHSHLSDIGESSNNGYDDHEDDSMSQASGGTAGGGSSYGHYHHPDDMHLANGGGVLGSDGDQRGKHRCPMCDKLFAWPKSLKIHLRTHTGEKPYRCDLCGKCFGRSDSLRGHKRTHADERLVQCHLCDVSCPSATELVQHQLVVHNIQPLEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00094618;
90% Identity
-
80% Identity
-