Abel001952.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anopheles bellator
Gene Symbol
-
Assembly
GCA_943735745.2
Location
OX030927.2:10831713-10836345[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 8e-06 0.00046 20.2 2.1 1 23 200 222 200 222 0.99
2 15 0.054 3.1 8.1 0.5 1 23 228 251 228 251 0.98
3 15 0.00028 0.016 15.3 0.6 2 23 272 294 272 294 0.93
4 15 0.037 2.1 8.6 3.0 1 23 300 323 300 323 0.91
5 15 1.5e-05 0.00085 19.4 0.1 1 23 519 541 519 541 0.98
6 15 0.00015 0.0089 16.1 0.3 1 23 547 569 547 569 0.99
7 15 0.012 0.71 10.1 2.5 1 23 667 689 667 689 0.98
8 15 1.4e-06 7.9e-05 22.6 0.9 1 23 695 717 695 717 0.99
9 15 8.3e-06 0.00048 20.1 0.5 1 23 816 838 816 838 0.95
10 15 0.0012 0.067 13.4 3.3 1 22 844 865 844 868 0.90
11 15 6.2e-07 3.6e-05 23.7 0.8 1 23 1035 1057 1035 1057 0.99
12 15 7.8e-07 4.5e-05 23.4 1.8 1 23 1063 1085 1063 1085 0.99
13 15 0.00025 0.015 15.5 0.8 1 23 1342 1364 1342 1364 0.98
14 15 3.5e-06 0.0002 21.3 2.9 1 23 1370 1392 1370 1392 0.99
15 15 0.0069 0.4 10.9 0.6 2 23 1399 1421 1398 1421 0.95

Sequence Information

Coding Sequence
ATGGAGCTGAAGGCGGAACGGCGCGAAACCGGCGAGGCAGAAGCaaaggaggaggaggacgacgacggtcagcCTTCGTCGAGCGCcaacgatggtggtggcaccTCGGACCAGGAGATAGTGGTCGGTATCGACGAGGATCACATCAAGTTTCTCACCAGCATGCACGACGAGGAGCCATCCAACGGGCACCATAATCCCGCGATGGAGcgccgtttcggtggcccggtggctgTGAATGGTGGTGGGGCCGGGACTGCGGGCAAACTCGCCCACcgcaaacaacagcaacatcaccagcagctgcagcagcagcagcagcagcagcagcaacatcattcCCTTCGATTGAATGGCATCTTCAACGGGAGAAATGGTAAAGCACCGCCAATTGCGTTCGGAAACGGTAGCAGAGCATCGCATCTCGCGTTTAGCGAGGAAtcggatgacgatgatggtgatgcgagcgacgacgatgacgatgacgacaaagATGACtcgtttgatgatgatgatgatggggacGAGGACGTGATGGCGGCGGCTGAATCGATCCTCTCGAAAACTGCCCAGCGATCGTCGGATTACACTCGCCGGTACCGGTGCGACCTGTGTCCAAGGGCCTTCCACCGTCCGGACTTTCTGCAGTACCATATGCGGACGCACGAGAAGAGCAATTCGTTCGAGTGTAAGCTTTGCTTCAGCATCTTCGCGTCGGATCCGGCGTTCGCCCACCACATCCGCACCGAGCACGCTGGGATGGGGTTGGCCGACGCACTGCCGCCGGTACCTGAGTCCGAAGCTCACTTTGCCGTTTGCACGTACTGTGACAAAACGTTCGCCGATGGCGATCAGCTGGAGGATCAcctccatcagcagcatctTGGGGTGCGACCGTTCAAGTGCAACATGTGCCCGAAAGCCTTTATCCGGATGGATTTTCTGCAGTGCCATTACGCCAAGTATCACAACTTTCATCGGTTCGGTGCGATCGGCGGAGGAGGAAACGGGGGAATGGGTGGTGACGGAGGAGGACTGTACTCCGCCAcgttcgatccgatcgaaagTGTTGTGCAGCGCGCAGCGATGACGATGGGAGGCCACGCTGCTGGGGGCCTTGGTGGCGGTCACGGCGGAGTACACGGCGGTGACCGAGGGGGATCCATCCAGGCGGCCATCCAGGCGGCCATCCAGCCACGATTGTCAGTAAGAAAGATGGAAGATTTGCTCGGCGGGCACGGTGACATGGCCGAAGGGCGACGTTTGATGATAGCGATGCCCAGCGCTAATTATTCACGCCGAACGTCACACACGGGCACCACGCTCGGTAGCAGTTCGAGTGAGGAGcacgaggatgacgatgacgacgaattGATGGTGTTGGGCGATGATGTCCCAATGGGCGCGGTGGGTAACGatcaccggaaacggaaagccgGCACAACGCTAACCAATGGTGGCAAAGCGCGTccagcgaaaaagaaagcaacggTAGGACTGGCAGCCAAGGCTGGGGTGCCAGTAGCGGTCCTTCCCCAGGAGGAAGTGGGTCAGTTTCGGTGCCCAGTTTGTGAGCGACGCTTTGTCCGCGAGCCGGAACTCATGGCCCATGTGCGCATTCACCCGGATCTACCCACTTACAAGTGTCCGTTGTGTGAATTAACCTTTATTGGATCGGACTACCTGAAGGGTCACCTGAAGAAGCACGTCGTTGGTGACGGTGAAGATCCGGACGCGCCTGGTGCGATCGACATGAAAACATTTAACGAATCAACTGCTACAACGGACATTTCATCGCCTCCGTCTTCCGCACTCACCGTAAACCGTCCATCTTCTACCGTATCTACGTCAGGTGGTAAGCTGCCATCGAAACACCCATCGAAACCACCGTCCACTGGCATCTCTCTGTTGAAACCGATCGAAGAGCGGAAACCACCCGacaaccagcagcatcatcagcaaccaCACGAGTACTGCATCAAAACGGCCGACGGCAAGTTTATGTGCACTGTGTGCGAGCGGCTCTTTTCCCACCAACAAACGGTGCGCATCCACTTTCGCATTCACACCAACGAAAAGCCGTACAAGTGTACGTTCTGTGGCGAATCCTACATACGGTCGGACTATCTCGAGCGCCACTTGAAGGTACACTTTAAGGACGGCGCACTTCCGGCTGCAGCGATCGCCAGTATGGCAGCCGCCGCTGCTCGGGATGTTGCGGCGGCCGTCGCGAACGGACGAACGGCGCCacagccaacagcagcaaccccaCCGCCAGCGCTGGTTGCGCCGAAGGAAGAATTCATTCCTGAAAGCACGACGATCACCGGTAAGAAAACTCCCACCCCGAGCGCAGCTCCGACGACATCGACACCGAAGCCCCTGATTGGCAGGGCCGGCTTGGCGCCGGAAAACTATCACTTTGCCGAGTCGAACGATGGACAGTTTGTGTGCAAGATTTGCGACAAAGTATTCTCCCACGTGGCCTCACTGCGGAAGCATGCACTGGCCCATACGGAGGAGAAACCGTTTCACTGCGAAATTTGCGATCGTTCGTTCAATCGGGTCGACTATCTGAAGGAACACTTTAAATCGAAACGCCATTTGCAGCTGGTGGCGGAAACGGCCGGGGGCACCGTTGAGAGGAACGTTGAGGAAGAGGAGGATGATTCCACGATGGATGATAgtgggccaccgccggctATCGCTGTGAAGCGTCACAGCAACAAATCGGGTACAAATCGGGGGAAGCAGAAGATTGACAATAAGCTGAACACGCCCAATACCGATGATGCTTGTGTAGCGGAGGTATTTCCGCTAGCGGCCAGCAGCTGTGGAAACAGTcggagcagcaacagtagcagtagcagcagcagttccagcagtagcagtagcagtaacagcaatagcagcagcagcagtagtagcggCAGTGGTGACGCAACAGTACGACAAAGTCCGGGAACGAAATCCATTGCCAATACCTCTTCAGCTGGTgccggcgatggtgatgacgCTGGCCGCGAAAGTAATGGGGGTTCCGTCGGCTCGACGCCAAGTGAATTTCATCGTTCCGATTACGAGCGGACAAGCGACGGGCGCTACAAGTGCAACCAGTGTGATAAAACGTTCGTTACGGCGGTCACACTCAAGATGCACATCCGGCTGCACACGGGCGAGAAACCGTACAAATGTGACAAGTGCGACAAGGCGTTCATTAGATCGGACTATTTGAAAACGCACGAAAAAACACACCGACAGCAGTCGTTCCTTAGTCTGCTAGCCTTAACTTCGAAGGAACCGAGTACGGCATCGGAAGCTGGAGAGGATTCCGATGGTGAAGAAGACGGGCACGCTAATGATCGGAACGAAGTCAGTAGATCATCAACAGTGATGAGCAATGGACCACAGGAGGCTATGGGAAATATGTCCAGTATTTTGAAGGATTCGATGGTTGGGAAAGGTGTACCGAGTgtggaggacgacgacgaagcggaagaaaacgaGTCAGGCGAAGAAGAGGATGAATCGGAGGACAGTGAAGAAGAGGAACAGGAGGTTATCAAAGTAACGGTCAAGGATGCAAGTTGCTCGGAGAGTGAAGAAGATGACGACAATGATGataacgacgatgacgaaaatGATAATTTGGACGAGGAAGAGGGGGAAGATGAGGAAGAAGAACTTGATGGCGATGACCACGGGGAAGATCGGCGGCAGAATAATGGTGTCGACGGTGACAGCAGAAGTGCAAATCGTGGGAGTGGACTATCGTTGCTGCAGTCTAAGAAAGAAGGCACCAAGTTGGAGCAACAAAGTGATCATGGTTTCCATAGCAACCACAGTCACCTCAGCGGTGGGGAAAGTAGTAACAACGGATACGATGATCACGAGGACGATAGTATATCACAAGCGAGCGGTGGTACGACGGGAGGCGGCTCTTCGTACGGCCAGTACCATCATCCTGACGATCTTCTGGCGAATGGTGGCGGAGTTTTGGGGGATGGTGaccaaaaaggcaaacaccGTTGCCCGATGTGTGACAAACTGTTTGCGTGGCCAAAGTCGCTGAAAATTCATCTGCGAACGCATACGGGCGAGAAGCCGTATCGGTGCGACCTGTGTGGCAAGTGTTTCGGGCGGTCAGACAGCTTACGTGGCCACAAGCGAACGCATGCCGACGAGCGGCTCGTTCAGTGCCATTTGTGTGACGTGAGCTGTCCAAGTGCGACGGAATTGGTGCAACATCAGCTCCTGGTGCACAACATTCAGCCGTTGGAGTGTTAG
Protein Sequence
MELKAERRETGEAEAKEEEDDDGQPSSSANDGGGTSDQEIVVGIDEDHIKFLTSMHDEEPSNGHHNPAMERRFGGPVAVNGGGAGTAGKLAHRKQQQHHQQLQQQQQQQQQHHSLRLNGIFNGRNGKAPPIAFGNGSRASHLAFSEESDDDDGDASDDDDDDDKDDSFDDDDDGDEDVMAAAESILSKTAQRSSDYTRRYRCDLCPRAFHRPDFLQYHMRTHEKSNSFECKLCFSIFASDPAFAHHIRTEHAGMGLADALPPVPESEAHFAVCTYCDKTFADGDQLEDHLHQQHLGVRPFKCNMCPKAFIRMDFLQCHYAKYHNFHRFGAIGGGGNGGMGGDGGGLYSATFDPIESVVQRAAMTMGGHAAGGLGGGHGGVHGGDRGGSIQAAIQAAIQPRLSVRKMEDLLGGHGDMAEGRRLMIAMPSANYSRRTSHTGTTLGSSSSEEHEDDDDDELMVLGDDVPMGAVGNDHRKRKAGTTLTNGGKARPAKKKATVGLAAKAGVPVAVLPQEEVGQFRCPVCERRFVREPELMAHVRIHPDLPTYKCPLCELTFIGSDYLKGHLKKHVVGDGEDPDAPGAIDMKTFNESTATTDISSPPSSALTVNRPSSTVSTSGGKLPSKHPSKPPSTGISLLKPIEERKPPDNQQHHQQPHEYCIKTADGKFMCTVCERLFSHQQTVRIHFRIHTNEKPYKCTFCGESYIRSDYLERHLKVHFKDGALPAAAIASMAAAAARDVAAAVANGRTAPQPTAATPPPALVAPKEEFIPESTTITGKKTPTPSAAPTTSTPKPLIGRAGLAPENYHFAESNDGQFVCKICDKVFSHVASLRKHALAHTEEKPFHCEICDRSFNRVDYLKEHFKSKRHLQLVAETAGGTVERNVEEEEDDSTMDDSGPPPAIAVKRHSNKSGTNRGKQKIDNKLNTPNTDDACVAEVFPLAASSCGNSRSSNSSSSSSSSSSSSSSNSNSSSSSSSGSGDATVRQSPGTKSIANTSSAGAGDGDDAGRESNGGSVGSTPSEFHRSDYERTSDGRYKCNQCDKTFVTAVTLKMHIRLHTGEKPYKCDKCDKAFIRSDYLKTHEKTHRQQSFLSLLALTSKEPSTASEAGEDSDGEEDGHANDRNEVSRSSTVMSNGPQEAMGNMSSILKDSMVGKGVPSVEDDDEAEENESGEEEDESEDSEEEEQEVIKVTVKDASCSESEEDDDNDDNDDDENDNLDEEEGEDEEEELDGDDHGEDRRQNNGVDGDSRSANRGSGLSLLQSKKEGTKLEQQSDHGFHSNHSHLSGGESSNNGYDDHEDDSISQASGGTTGGGSSYGQYHHPDDLLANGGGVLGDGDQKGKHRCPMCDKLFAWPKSLKIHLRTHTGEKPYRCDLCGKCFGRSDSLRGHKRTHADERLVQCHLCDVSCPSATELVQHQLLVHNIQPLEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00097218;
90% Identity
-
80% Identity
-