Basic Information

Insect: Anopheles cruzii
Gene Symbol: Rfx2
Assembly: GCA_943734635.1
Location: OX030880.1:32281215-32288270[+]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 9.7e-37 7.5e-33 112.8 0.0 3 78 398 473 396 474 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	9.7e-37	7.5e-33	112.8	0.0	3	78	398	473	396	474	0.98

Sequence Information

Coding Sequence: ATGGCTACACGATTAGCGACACAACGAAACTTTATTACCGTAATCCCAGCAACTGGCATTAAAGGGGACGACGCGAACGCAGCCCAAGCATCTGCCGAACCACTGGATGCTACGATCACACCCAATGGCTCCGCCAATTCCGACACACCAGAAGCATCGGTCAACGTTACAAGTGCAACACCAGTGATGGCTTCGTGTACCACCGGTACGTCGCAGATACCGACGATTGCCGTCGCAGGAAGTCTTAAAAATGGCACCATAAAACCCGCCCTTTTGCCCACCGCCTTACTGAACAACTCGAACATCATGAGCCTACTGGGCAACACAACCAACGGCCTCTCTTTGCAACAGATGATACAACAGCAGAAAAAAATAGTGATTCATCCCAACGGAACCGTCATTAATATTCTGCATTCTGTCAGTGACGAGAGTGAAAGCGTAGATTTAAAGGCAGACAATGAAAAGCTCTTGGACAACCCTGCAAACGATAGTACCGAAAGTGGCAGTACTTCGGAAGCTACAGCCGACGACACAGCACAAGTTACGACCCAAGTGGCCGTAGTGCAGGCACAAAACTCAGCCGATGGCACACCGCAGTATATCACTGTTACTGTCTCATCGCCCGACAATGGCCCCAACCACCACACGTACGTGCAGTATGTCGACTCGGATATGTACAATGCCTCCAACCAGGGCCAGACACAAATGTCGTACCCCGTGTATACCGTCGGCGATTACGGTTCGAGCGGCCAGCAGCAACAGCAACAGCAGCAATATTATGCTACCGGAGGAAATTATAGTACGACCGGAACCGGTACCAACACCACACACTCGGACGCCGGTGGAACCGGAAACGGTTCGACCAACGGTGGTGCCAACGCGGCTCCGAATGGAACCGTTAATGGAACCGTTTCCACCGGTAACGGGAGTGCACCGAATGCTGGAACCGCTAATCAGCAGCAACAGCAGCAGTACATTGTACCGGTCGACGAATCGGTACTGCTCGGTTCGGCCACCGGTGTCAACGGGAGCAATGGGAGCGCACCCGGAACGCAACAGCAGCAGTCGGATTCGTCGCCCCAAAACATGACGGACGTAGTCTCGTATTTGCACGCACAGCAAGCGTCTGCAGCATCGGGCCAGGATCTCGATCACAGCCCCAATCTGGCCCATGCTGCTCGCGTTCTGCCCGCTACGGTCAATTGGTTGATGGAAAACTACGAGACGGCGGACGGTGTGAGCTTGCCACGGTCGACGCTCTACAATCACTACATGTGGCACTGCAACGAGAACAAGCTGGACGCGGTCAATGCGGCCAGCTTCGGCAAGCTGATCCGTTCGGTGTTCAGCGGGTTGAGGACGCGCCGGTTGGGGACGCGCGGTAACAGCAAGTACCACTACTACGGCATTCGCATCAAGCCAACGTCCCCGCTGGTCAACGCCATCGACTGCAAGCCGCAACACTCGGGTCAGCTGATGGGTGGCCACCATCAACAGCTGGGCAACGGGAACGGGTGCCTCGGTGGTGGCAACGGAAATGGTATGCACGTCCACGGCAACACCGGAGCAACGGGTGGCAACGGTGGGACCGGTATCCAAGCTAACGGGTCGATGGGAGCCGGCGGTGGCCACGGTGGTGTAACGCATCACCAAGGAGCGGGCGGAATGTCGCTGGGCCATGGGCGGGGTCCGAAGAAGAACAGTTTTAAGGCGGAAATGCCCGATTCGTGCGCACAGTATCTGGGTGATCCGAGTGGTGCCATACCGCAGTTTCCGATCATCGACATGATCCACCCGCTGCCGGACGAGATAACGCTGGAGGACGTGGACACGCTCCGCTCGATCTACCGCGAGCACTGCGAAGCGTTTCTGGATGCCATCCTGAACCTGGACTTCAACATGATCGAGTCGCTGTGGCGCGAGTTTTGGCGCGCGGAAAACAACAACAACAACGGGGACGAGTGCGAGGAAGAGAAGTATCTCAGCAAACAGAAGCTGTACCTGCTGACGCAGTTCGAACCGGTGCAGGAGTTTGTGAAGCACGTCGATTTAAAGTTCTACCAGAACATGGTCGACGTGCTGATCCCGGACGTGCTGCGCCCGATACCGACCGGCCTGACGCAGGCCATTCGCAATTTCGCGAAAAACCTCGAAAGTTGGCTCACGTCGGCGATGAGCGGGTGCCCGGAACCGATCACGGCCATCAAGCTGTCGGCGGTGTCGGCCTTTGGCCAGACACTCCGCCGCTACACGTCGCTCAATCACCTGGCCCAGGCGGCCCGGGCCGTGCTGCAGAACGGCACGCAGATCGCGCAAATGCTGAGCGACCTGAATCGGGTCGACTTCCGCAACGTGCAGGAGCAGGCATCGTGGATCTGCCAGTGCGATACGTCGATCGTGCAGCGGCTAGAGAACGACTTCAAGGCGGCCCTCCAGCAACAGAACACGCTGGAGCAGTGGGCCTGCTGGTTGCAGAACGTGGTGGACGACGCGCTGCAGGATTTCCGCGGCAAACCGAGCTTCGTCAATGCGGCGCGCCAGTTTCTGCTCAAGTGGAGCTTCTACAGCTCGATGGTGATCCGCGACCTGACACTCCGGTCGGCCGGCAGCTTCGGGAGCTTCCACCTGATCCGGCTGCTGTACGACGAGTACATGTTCTTCATCATCGAGCACAAGGTCGCGAAAGCGACCAACACCACCCCGATCGCGGTCATGGGAGAGAAAGTAGCTCCACGGCCGACCCACGACGATCTGGACAGTATGCTGTACAGCACCGAGTACGGTATGGTGAACGTGAAGCTCGAACCGAACGCCAAGCGGATGCGGAGTTAG
Protein Sequence: MATRLATQRNFITVIPATGIKGDDANAAQASAEPLDATITPNGSANSDTPEASVNVTSATPVMASCTTGTSQIPTIAVAGSLKNGTIKPALLPTALLNNSNIMSLLGNTTNGLSLQQMIQQQKKIVIHPNGTVINILHSVSDESESVDLKADNEKLLDNPANDSTESGSTSEATADDTAQVTTQVAVVQAQNSADGTPQYITVTVSSPDNGPNHHTYVQYVDSDMYNASNQGQTQMSYPVYTVGDYGSSGQQQQQQQQYYATGGNYSTTGTGTNTTHSDAGGTGNGSTNGGANAAPNGTVNGTVSTGNGSAPNAGTANQQQQQQYIVPVDESVLLGSATGVNGSNGSAPGTQQQQSDSSPQNMTDVVSYLHAQQASAASGQDLDHSPNLAHAARVLPATVNWLMENYETADGVSLPRSTLYNHYMWHCNENKLDAVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPTSPLVNAIDCKPQHSGQLMGGHHQQLGNGNGCLGGGNGNGMHVHGNTGATGGNGGTGIQANGSMGAGGGHGGVTHHQGAGGMSLGHGRGPKKNSFKAEMPDSCAQYLGDPSGAIPQFPIIDMIHPLPDEITLEDVDTLRSIYREHCEAFLDAILNLDFNMIESLWREFWRAENNNNNGDECEEEKYLSKQKLYLLTQFEPVQEFVKHVDLKFYQNMVDVLIPDVLRPIPTGLTQAIRNFAKNLESWLTSAMSGCPEPITAIKLSAVSAFGQTLRRYTSLNHLAQAARAVLQNGTQIAQMLSDLNRVDFRNVQEQASWICQCDTSIVQRLENDFKAALQQQNTLEQWACWLQNVVDDALQDFRGKPSFVNAARQFLLKWSFYSSMVIRDLTLRSAGSFGSFHLIRLLYDEYMFFIIEHKVAKATNTTPIAVMGEKVAPRPTHDDLDSMLYSTEYGMVNVKLEPNAKRMRS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00094231;
90% Identity: iTF_00094231;
80% Identity: -