Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:92089999-92092953[+]

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.46 1.1e+03 -0.1 0.0 26 54 220 248 204 248 0.86

2 12 1.1 2.6e+03 -1.3 0.2 17 33 307 323 302 336 0.72

3 12 4.2 1e+04 -3.2 0.0 27 46 421 440 419 444 0.85

4 12 1.5 3.6e+03 -1.7 0.1 27 32 590 595 586 605 0.76

5 12 0.012 28 5.0 0.0 21 45 694 718 688 721 0.89

6 12 0.00059 1.4 9.2 0.0 21 44 722 745 718 749 0.91

7 12 0.011 25 5.2 0.1 21 45 750 774 746 779 0.89

8 12 0.28 6.6e+02 0.6 0.0 21 48 802 829 789 834 0.84

9 12 0.00042 1 9.6 0.1 21 52 831 862 821 863 0.82

10 12 0.1 2.5e+02 2.0 0.0 22 44 888 910 885 914 0.88

11 12 0.0037 8.9 6.6 0.1 21 48 915 942 910 946 0.86

12 12 0.00063 1.5 9.1 0.0 21 45 943 967 939 973 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.46	1.1e+03	-0.1	0.0	26	54	220	248	204	248	0.86
2	12	1.1	2.6e+03	-1.3	0.2	17	33	307	323	302	336	0.72
3	12	4.2	1e+04	-3.2	0.0	27	46	421	440	419	444	0.85
4	12	1.5	3.6e+03	-1.7	0.1	27	32	590	595	586	605	0.76
5	12	0.012	28	5.0	0.0	21	45	694	718	688	721	0.89
6	12	0.00059	1.4	9.2	0.0	21	44	722	745	718	749	0.91
7	12	0.011	25	5.2	0.1	21	45	750	774	746	779	0.89
8	12	0.28	6.6e+02	0.6	0.0	21	48	802	829	789	834	0.84
9	12	0.00042	1	9.6	0.1	21	52	831	862	821	863	0.82
10	12	0.1	2.5e+02	2.0	0.0	22	44	888	910	885	914	0.88
11	12	0.0037	8.9	6.6	0.1	21	48	915	942	910	946	0.86
12	12	0.00063	1.5	9.1	0.0	21	45	943	967	939	973	0.91

Sequence Information

Coding Sequence: ATGCTCGGTAAATATGCTGACGCGAGTTCCAGCTCGATGATAAACCTGGAAAATGGGCTCCGCAACCGTGTGCTGTACCATCAGAACATGATGGGTATGAATCTGATGGCCGAATTTTACCACAACCCTCTAATGAATTCCTCCGGAAGCAACGGTGCCGGTGGTAGCGACGCTGTTGGAGCCGGCTCAATGCTATCGCCATCGCAAAAGATGCTCAACATTCTGTCAGTTAGCGCTGGAAGCAATCTGCAACCGCATCACACCGGAAATAGTTCCGTAGTGTCAACAGTGCCGGTAGGTTCTGCATCGACGGCGTCAAGCGGTTCATCGCAGCAATCGTTGGTACAGTTGCAATGTCAACTTTGCCAAAAGTACTTTATTTCCGGGGCGGCGCTCGCGCAGCATATTAAAACACACGAAAATGATTACCTTGCGCGGGAAGAATCCGGTCCCAGCGGCGGTTACAGTCAACAGCAGTCGATAACGTCCGCTCCATCGCTTGTAACGACGGTGGCTTCGAGTAGCAAAACTAGTTCACCATTGCTTGCACAGCAAAGCATCAAGAGTGAGTATATTGTACGTAGTACGTCGTCTTCGTCTGTGCCCTTGCCAGGTGGGAACCAATTTCCTACAGCATACGGTATTACGAAACAGTTTGACTGTCACATCTGCCACAAATCGTTCATGACGATGATGAACCTTAACCTGCATATGAAAATCCACGAAGAGTTCAAACCGGCTGTGGTGTCTTCTCTTGCGAATCCGTCCGGTGGTAGCAGCGGAACCGTAACGTCACAGGCGCAAAAGCCGCTCAACATTATGTCGCACCATACCAGCGCGGGAAGTACTCCACAACTGCAGCACTCCGTAAATGGTTCGGTTGTGACGACAATAGCACTAGGCGCCGTGCCGTCGACATCGAGTGGTACATCGCAGCAAGCGTTGCAATGTCAAATTTGTCAAAAGTACTTCATTTCCGGCACTGCACTGGCGCAGCATATTAAAACACACGATAATGACTACCTGGCGCGGGAAGAATCCGGTCCCGGTGGCAGCTATAGTCAGCAGCAATCGTTAACGTCGGCACCCTCGCTAGCAACGGCAGTGGCATCGAGCAGTAAAACTAGTCCCCCACTGCTTGCACAGCAGAGCATAAAAAGTGAGTACATTGTACGAAGTGGTGCATCATCTTCTTCTACCGTGCCCGTGCCAGGTGGGAACCAATTCGCTCCCGCGTATGGTATTACGAAACAGTTTGACTGTCACATCTGCCACAAATCGTTTATGACGATGATGAACCTTAACCTGCATATGAAAATTCACGAAGAGTTGAAACAAACAGCTGCAACCCACGTCTACACCCATGCCCCGACCCTTGGCGCTACAAGTGCAGGGACATCGTCTAACGAttatcatcaccaccatcagcagcaccaCAACAATTATCACAACAACCCGCAGCAGCACATTTCGATGGTGGCAGCGACAACGATTGGGACGGATGGTGCGTGCCAGATTTGCCATAAAACATTCAGCACGGTCGAGCAATTTACGGCGCACATGAAGATTCACGAAAACGAGTTTAGGAATCGTGCGCTCTATCACTCCGGTAGCTCCAATACCATCGGTCCCGGTGTAGAAGGAAGTGTAGTTGTCCAGAGTACGCCAACGACGACAGATTCTTTCTATTCGTCCACTCAATCACAGCCGATCCTCGCACAACAACAAACGACTGCACCACAGTTTGATGCCATGAAAGGATATCGATGTCCCATTTGTCACAAAATGTCCAGCAACATCATCGAACACATCAAACAACACGAAGGGCAGCTAATGTTAGGTGAAGGGGCTGCAAGTAGTCGAAGTGGAACGACACCACCCACGCCGGATGTGACATCGCCTGCGCCGGAAGGGTTGTCGTACCATCCGATGAATGAAGATACGCAATCATCGCTCGAAGGAGACGACAGCGAAGGCCAGACGGGAGAAGGTGCCGATGTTCGAAAGCACGAGTGCCTACTCTGCCACAAAAAGTTCTCGAGCTCGGGAAATTTAGCCATTCACATACGGGTGCACTCGGGCGAGAAACCGTTCAAATGTAGCGTCTGCGGGAAGGGTTTCATCCAGTCGAACAACCTGGCGACGCATATGAAAACGCACACCGGCGAAAAGCCGTACGCGTGCACGATTtgcgggaaaaacttttcgcaATCGAACAACCTGAAAACGCACATCCGGACGCACACCGGCGAAAAGCCTTACGCGTGTACCATCTGCGGGAAGCGGTTCAACCAGAAGAACAATTTGACCACGCACATGCGCACGCACCAGCTGGTGTGCATGGTGTGCGGCGTGCAGTTCATGCATCCGTCCGACCTGGCCAATCACATGAAGTTTCACAATGACGAAAAGCCGTACATCTGCTCGGTTTGCAACAAGGTGTACCTCAACCTGGACGAGCTTACCGAGCACATGAAGAAGACCCACAACCAGGTTAAGCCGTACCGGTGCCACATCTGCGACAAAACGTTCACCCAATCGAATAACCTGAAGACGCACATCAAAACGCACATCTTTCAGGATCCGTTCAAATGTCAGATGTGTTCGCGCTCCTTCCAGAAGGAGGACGACTACTCGCAGCACATGCTGGTCCACACGGCCGACAAACCGTACGAGTGTACGTACTGCGGGAAGCGGTTCATTCAGTCCAACAACCTGAAGACGCACGTCCGGACGCATACGGGCGAAAAGCCGTACCGTTGTACAATCTGCGCAAAGCACTTCAACCAGAAAAACAATCTCAATACACACATGCGCATCCATACCGGCGAAAAGCCCTTCGAGTGCACCATCTGCGATAAGCGGTTTAACCAGTCGAACAATTTGAACAAGCACATCAAAACGCATGGTCAAGAAAAGGacacgcagcagcagcagccacagcACGCAAGTTGA
Protein Sequence: MLGKYADASSSSMINLENGLRNRVLYHQNMMGMNLMAEFYHNPLMNSSGSNGAGGSDAVGAGSMLSPSQKMLNILSVSAGSNLQPHHTGNSSVVSTVPVGSASTASSGSSQQSLVQLQCQLCQKYFISGAALAQHIKTHENDYLAREESGPSGGYSQQQSITSAPSLVTTVASSSKTSSPLLAQQSIKSEYIVRSTSSSSVPLPGGNQFPTAYGITKQFDCHICHKSFMTMMNLNLHMKIHEEFKPAVVSSLANPSGGSSGTVTSQAQKPLNIMSHHTSAGSTPQLQHSVNGSVVTTIALGAVPSTSSGTSQQALQCQICQKYFISGTALAQHIKTHDNDYLAREESGPGGSYSQQQSLTSAPSLATAVASSSKTSPPLLAQQSIKSEYIVRSGASSSSTVPVPGGNQFAPAYGITKQFDCHICHKSFMTMMNLNLHMKIHEELKQTAATHVYTHAPTLGATSAGTSSNDYHHHHQQHHNNYHNNPQQHISMVAATTIGTDGACQICHKTFSTVEQFTAHMKIHENEFRNRALYHSGSSNTIGPGVEGSVVVQSTPTTTDSFYSSTQSQPILAQQQTTAPQFDAMKGYRCPICHKMSSNIIEHIKQHEGQLMLGEGAASSRSGTTPPTPDVTSPAPEGLSYHPMNEDTQSSLEGDDSEGQTGEGADVRKHECLLCHKKFSSSGNLAIHIRVHSGEKPFKCSVCGKGFIQSNNLATHMKTHTGEKPYACTICGKNFSQSNNLKTHIRTHTGEKPYACTICGKRFNQKNNLTTHMRTHQLVCMVCGVQFMHPSDLANHMKFHNDEKPYICSVCNKVYLNLDELTEHMKKTHNQVKPYRCHICDKTFTQSNNLKTHIKTHIFQDPFKCQMCSRSFQKEDDYSQHMLVHTADKPYECTYCGKRFIQSNNLKTHVRTHTGEKPYRCTICAKHFNQKNNLNTHMRIHTGEKPFECTICDKRFNQSNNLNKHIKTHGQEKDTQQQQPQHAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00108044;
90% Identity: iTF_00108044;
80% Identity: iTF_00109283;