Basic Information

Insect: Anopheles coustani
Gene Symbol: -
Assembly: GCA_943734705.2
Location: OX030900.2:23647947-23650070[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.68 53 4.6 2.2 2 23 245 267 244 267 0.90

2 14 0.00016 0.012 16.1 0.5 2 22 287 307 286 307 0.94

3 14 0.0016 0.13 12.9 2.6 1 20 312 331 312 334 0.93

4 14 0.36 29 5.5 0.8 1 23 340 363 340 363 0.91

5 14 0.0027 0.22 12.2 0.8 1 22 375 396 375 396 0.95

6 14 0.021 1.6 9.4 1.0 1 23 400 423 400 424 0.96

7 14 0.011 0.83 10.3 0.1 3 23 437 458 435 458 0.90

8 14 0.003 0.24 12.1 1.4 1 21 476 496 476 497 0.95

9 14 6.5e-06 0.00051 20.4 0.6 1 23 504 526 504 526 0.98

10 14 1.1e-05 0.00084 19.8 1.9 1 23 532 554 532 554 0.98

11 14 1.1e-06 8.3e-05 22.9 3.6 1 23 561 583 561 583 0.97

12 14 0.00023 0.018 15.6 4.7 1 23 589 611 589 611 0.97

13 14 9.9e-08 7.8e-06 26.2 0.5 1 23 617 639 617 639 0.98

14 14 9.6e-06 0.00076 19.9 1.8 1 23 648 671 648 671 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.68	53	4.6	2.2	2	23	245	267	244	267	0.90
2	14	0.00016	0.012	16.1	0.5	2	22	287	307	286	307	0.94
3	14	0.0016	0.13	12.9	2.6	1	20	312	331	312	334	0.93
4	14	0.36	29	5.5	0.8	1	23	340	363	340	363	0.91
5	14	0.0027	0.22	12.2	0.8	1	22	375	396	375	396	0.95
6	14	0.021	1.6	9.4	1.0	1	23	400	423	400	424	0.96
7	14	0.011	0.83	10.3	0.1	3	23	437	458	435	458	0.90
8	14	0.003	0.24	12.1	1.4	1	21	476	496	476	497	0.95
9	14	6.5e-06	0.00051	20.4	0.6	1	23	504	526	504	526	0.98
10	14	1.1e-05	0.00084	19.8	1.9	1	23	532	554	532	554	0.98
11	14	1.1e-06	8.3e-05	22.9	3.6	1	23	561	583	561	583	0.97
12	14	0.00023	0.018	15.6	4.7	1	23	589	611	589	611	0.97
13	14	9.9e-08	7.8e-06	26.2	0.5	1	23	617	639	617	639	0.98
14	14	9.6e-06	0.00076	19.9	1.8	1	23	648	671	648	671	0.98

Sequence Information

Coding Sequence: ATGGACATCCTAATCGAGCCAGATTGCTACAAGGTGTGTCGTATTTGCATGGAAAGCTGCGAGGATGATTTCGTATGCGTATACGACGAGTTCGAGGATGTGATACTCTGCGAGGTGATCCAGGAGTGTGCCCACGTGGAGATTCGCAAGAACGATGCACTCCCCCGGAACGTTTGTCGAAGCTGTGCACAGTATATGCTAATCGCTTACCACACCATTCAGAAGTGCCGTGAATCGGACGTGACTCTACGATCCATTTTCAAGCATGAGCTTAATCTACACTGCGGTACTAAGATGGGGACCGACGCTGGGCCGAGATGTCCCATGGTCCTGCAGCCGGAAGATATGGATCCGTCAGACTATGAATTTCTGCTGTCCGACGCGTACGACGACATGTTGCTTGAGAATGGTGCTAGAATATTGCTGGAAGAACACAATCGCTGCAATTTCACGCCACCGATCGATAAGAACAATCAGTGCTCGGAGGAAAACAACTTGCCCGGAGAACATCTGGCACCAGATCAACAGGAATATCAGCAGGGAACGGAGCAAGCATATAGGGAACCGGAAATGATACTAGAACAACAACCGCTGGAATCATTGCACATGACTTACGCGGCTCGTACACACGAAGAACCAAAGTTCGCGACAAATTTGTTGAGAGCCGAAAAAACGTACGAATCTAGTGAAACTAATGACGATGAACCCGCATGTGTGCCCCAAGAGCAAAAACAATGTTGCGGCTGTAAGAAGCTCTTCGACAACGAACAAAGGCTTCGTGAACATTCGCAGGCCGTGCACCTCCCGGCGGCGCCGCCCACCACCACTGATTGCCCCAAGACCGAAGGGGAACAGCTTCGGTGCGGAGTATGCTACCGAAAGTTCAGTACGCTGAGCTTGCTGAAGGAACACCAACGGTCGGTTAACCGGAAGTACACTTGTGCGCAGTGTGGCAAGCGCTTCATGACCCAGACCAATCTCGACATACACAGCAAGTGCCACAAGAACAAGGAAACGTACAAATGTTGCGGTTGCCGTATGGACTTCGAGCAGGAACTGGACCTTCTGCTCCACTCGCAAGAGGTCCACCGACCCGAGCGGACCGTTAACTCGGAAAAGGCGTTCGAATGCGAAACGTGCTACCGCCGGTATCCAACGCGAAAGTCCCTGGCAACGCACAAACGTATGATACGTCAGTTTCAGTGCcaactttgtggggcgatttttATGAAGCAGCTCTTTCTTACGCTTCACCTCGAGCGGGTACACCACGGGGAGGTGGTAATGGAGCAGCAAAGTCGCCGATGCTGTGGCGGTTGTCGCGAGGTGTTCGTCAATGCTGCTGCACTGCGGGAGCATGCGCTGCAGGTGCACAAACCGACGGACGGTTCCACCGGATCATCCGGCACGGACGATGGTAAACCGTTCGAGTGTGACGTCTGCCGGAAACGGTTCTCCTCGATGTTCTTTCTGCTGCAGCACCAACAAAAGGTGTTCCGGGAAAAGTGCTACCCGTGCTCGATTTGCGGCCGCACGTTCGGGCGGGCCCACGACCTCTCCAACCACGAGACGACCCATTCGAACGAGATGCCCTTCGAGTGTGGCGTTTGTGGGCGGCGGTTCAAGAACAAGCTGTATCTCAAAAATCACCGTAAACTGCACACGAACAGCACGAAGGACCACGTGTGCGACGAGTGTGGTAAGTGCTTCCGCACGAAAGAATTGCTCAAGACGCACCTGATCAGCCACTCGCAAGAGCGCAAACATTCCTGCACCGTCTGCACGGCTACCTTCAAGCGGTTGCAGTGCCTGAAGATTCATATGCGCATCCATACGCGCGAGAAAGCGTTCGAGTGTCCAATCTGCCGGAAGCGGTACGTGCAGTCGTCCGATCTGAAGCGCCACATGTTGATACATAATCCGGGCGACGAGGGGAAACCGTTCCAGTGCGAGTACTGCCTTCGGCGGTACCCGCGCAAGGACTACCTCAAAGTGCACATCCGCAAACAGCATCCGCACAAGCCGGAGACCTTGAACATCGTGGGGACGTTCGAGGCAGTCGCTGCCGGGCTCGACGGGATCGAACCGATGCCGATTGCGGTGGAAGACTTTATGGTTTGCTGA
Protein Sequence: MDILIEPDCYKVCRICMESCEDDFVCVYDEFEDVILCEVIQECAHVEIRKNDALPRNVCRSCAQYMLIAYHTIQKCRESDVTLRSIFKHELNLHCGTKMGTDAGPRCPMVLQPEDMDPSDYEFLLSDAYDDMLLENGARILLEEHNRCNFTPPIDKNNQCSEENNLPGEHLAPDQQEYQQGTEQAYREPEMILEQQPLESLHMTYAARTHEEPKFATNLLRAEKTYESSETNDDEPACVPQEQKQCCGCKKLFDNEQRLREHSQAVHLPAAPPTTTDCPKTEGEQLRCGVCYRKFSTLSLLKEHQRSVNRKYTCAQCGKRFMTQTNLDIHSKCHKNKETYKCCGCRMDFEQELDLLLHSQEVHRPERTVNSEKAFECETCYRRYPTRKSLATHKRMIRQFQCQLCGAIFMKQLFLTLHLERVHHGEVVMEQQSRRCCGGCREVFVNAAALREHALQVHKPTDGSTGSSGTDDGKPFECDVCRKRFSSMFFLLQHQQKVFREKCYPCSICGRTFGRAHDLSNHETTHSNEMPFECGVCGRRFKNKLYLKNHRKLHTNSTKDHVCDECGKCFRTKELLKTHLISHSQERKHSCTVCTATFKRLQCLKIHMRIHTREKAFECPICRKRYVQSSDLKRHMLIHNPGDEGKPFQCEYCLRRYPRKDYLKVHIRKQHPHKPETLNIVGTFEAVAAGLDGIEPMPIAVEDFMVC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00094081;
90% Identity: iTF_00107876;
80% Identity: iTF_00109293;