Basic Information

Insect: Anopheles coustani
Gene Symbol: Hr39
Assembly: GCA_943734705.2
Location: OX030900.2:3335450-3338704[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.19 9e+02 -0.9 1.4 98 176 182 262 108 279 0.68

2 5 0.72 3.5e+03 -2.8 1.0 63 131 363 380 331 422 0.42

3 5 0.028 1.3e+02 1.8 4.1 43 76 451 483 423 517 0.54

4 5 7.6e-08 0.00036 20.1 0.0 1 20 581 600 581 606 0.93

5 5 5.6e-77 2.7e-73 247.8 0.0 156 408 680 942 667 942 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.19	9e+02	-0.9	1.4	98	176	182	262	108	279	0.68
2	5	0.72	3.5e+03	-2.8	1.0	63	131	363	380	331	422	0.42
3	5	0.028	1.3e+02	1.8	4.1	43	76	451	483	423	517	0.54
4	5	7.6e-08	0.00036	20.1	0.0	1	20	581	600	581	606	0.93
5	5	5.6e-77	2.7e-73	247.8	0.0	156	408	680	942	667	942	0.91

Sequence Information

Coding Sequence: ATGAAAATAATGACATCCACGGAAGTAAACGGAGCcggaggtggtggaggaggtggcGGAGCGGCACCGGCTAGTCGTGGAGGGAACGTGTCGGTCACAACGATTAATCGCGACGATGGAGGAGCCGATGCGGCCATGGTTGCCAAACTAGCGACGTCCAGCGGGAGTGTGTCGGGAGtgaacaataacaacaacactcttagtaacaacaacaacaacaatgtgagcagtagcagcaacaacaataacaacgtAACTCCTGGCGCAAGTCCGGCGGGTACGACGGCACCGCCGTTCTTCGGAAACGTTGGTGGAGGGATCCGGATAACCGTGCCGAAGATGGAGGAATCGGACGAATCCGACACGGAGCTGTCGAACATCGAAAAGACAGTGTCCGCCGTTGCACTGACCAATGGGGTGAATATGCGGGAGGAACGAAGCGCCAGCAAGGGGGCACCCCGGCCCATGTCCTGGGAGGGTGAGCTGTCGGAACCGGAGGAACCGATGCTGGTGGACAACGAGAACAGCAGCTCGGGCTCGAGTGTGGGTAAGCTGGCACAGAACGCACCGTCGTCTTCCCCCGTGGCCATGATTGTGCCGAAGCAAGAAGAGGATCACGAACTGCCCACTAGTGGACCGGGCATTACGGAACCGCTGGCACTGACCGCATCCAGTAGTAGCAACAGCGGTTACGCCAGCGTTTCCCTGCACGGCCATAGCAGTAGTACCCACGCAGGGTTGAGACATTCGAGCAGCTCAAGCAACTCACCACTTCCGAACCGTATGCTGATCAAACCGGAAGCAGGGCTTCCACTGATCAACCCGGGCCTGGCGTACAACGTCGCTGGTCTGGGCCAGCATCCATCGTCCAACATTCCAACAGCAGCCGGAGGAGCGTCAGCCTTCAAGAAGGGTCTTCCGGATGTGATAAACTTGAAGTACGAGCTTCCCCCCGGTGGGGTGGGCGATCCGGGTGGTGGTAGTGCGCTGCCCCCGAACGCTATCCACTCTCCGCTGCTCGTCCGCTCCAAGACGACACTACTGCCGGCCAATCCGAGCCCCGACTCGGCGATCCACTCGGTGTACACGCACAGCTCGCCCAGCCAGTCTCCGCTCACGTCACGCCACGCTCCGTACACTCCTTCGCTCAGCCGGAACAACAGCGATGCGTCGCACAGTAGCTGCTACTCGTACAGTTCAGAGTTCAGTCCGACGCATTCGCCCATCCAGGGACGGCACAGCATATTCGCCGGCGGTGGAAACGGCGGAGGCGTCGCGTCCTTCAATGGGTCTCCCCTGCATCATTCAGTATTATTCAAACCGATGCTGGACAGCGAACAACATcatcttcagcagcagcaccaccagcagcagcagcagcagcaacatcagcagcaactccagcatcagcagcagcagcagcagcagcaacatcaacaacagcagcaagctCTCAAGCAGGAGGAATTACTCTACGATGGGGAGCATCTTCCATCACCCGGCATTTCCCGACAACAATTGATCAATAGTCCCTGTCCGATTTGTGGCGATAAAATCTCCGGTTTCCATTACGGCATCTTTTCGTGCGAGTCGTGCAAAGGTTTCTTCAAGCGCACGGTCCAGAACCGTAAGAACTACGTGTGCCTTAGGGGGGCGGCCTGTCCGGTGGCGATAGCGACGCGCAAGAAGTGTCCTGCCTGCCGGTTCGAGAAGTGCCTTCAGAAGGGGATGAAGTTGGAAGCTATTCGTGAGGATCGTACACGTGGTGGTCGCTCGACGTACCAGTGCTCGTACACTCTTCCTGGGCCGTTGGTGAATACGGCCGGCATGCAGGGTGGCGAGTCGCCCGGGGTCGGTGCATTCCAGTACGGAGGATCGGTCCGATCGCCGTACGCtgccggtggcggtggaggagtTGTTTCGAGCCAGCAGATGAAGGTGGAAACGAACGACGGCGCAGGTGGTATGATGATGCCCGGCGGGGGTAGCAACGGTGGACTGAACGGGATGAGCAATGGACCAAGCGCCGATGGAAACGGTGGATCCAGTGGAGGTGGAAATCATATGCAACCAGGCATTCCAGTTCTGTTACAGGAAATTATGGACGTTGAACCATTGTGGCAGTACAACGCAGCGGAGCTGGCTCGGCTGAATCAACCTCCGCCGGCGGGTAACTGTACGAACATTGCGAACAATCCGCTGCTCTGCAGTGCCGGCATCTCTTCCGAGAGCAGTCCCGATCTGATTGCAAACCTCTGCAACATAGCTGACCATCGCCTGTACAAGATCGTCAAGTGGTGCAAGAGTTTGCCGCTTTTTAAGAATATTTCGATCGACGACCAGATCTGCCTACTGATCAACTCCTGGTGTGAGCTGTTGCTGTTTTCATGTTGCTACCGTTCAATTTCAACACCGGGAGAGATCAAGATCTCCCTTGGGAAGTCGATCACACTGGAACAGGTTAAGAATAGTGGACTACAGACTTGCATCGAAAGAATGTTAAATCTAACCGATCATCTGCGACGATTGCGCGTCGACAAGTACGAGTACGTGGCGATGAAAGTGATTGTACTGCTGTCCTCGGACACTTCCGAGTTGAAAGAATCGGAAAAGGTTCGGGCGAGCCAGGAGAAAGCCCTCCAAGCGCTGCAAGCCTACACGTTGGCCTACTATCCGAAATCGCCGGCCAAGTTTGGGGAGCTTTTGCTGCGGATTCCAGAACTACAGCGAACATGTCAGGTCGGAAAGGAAATGCTCAACATCAAATCCAAGGACGACGAGGAACCCTCGTTCAACCTGCTGATGGAGCTGCTCCGCGGGGAGCACTGA
Protein Sequence: MKIMTSTEVNGAGGGGGGGGAAPASRGGNVSVTTINRDDGGADAAMVAKLATSSGSVSGVNNNNNTLSNNNNNNVSSSSNNNNNVTPGASPAGTTAPPFFGNVGGGIRITVPKMEESDESDTELSNIEKTVSAVALTNGVNMREERSASKGAPRPMSWEGELSEPEEPMLVDNENSSSGSSVGKLAQNAPSSSPVAMIVPKQEEDHELPTSGPGITEPLALTASSSSNSGYASVSLHGHSSSTHAGLRHSSSSSNSPLPNRMLIKPEAGLPLINPGLAYNVAGLGQHPSSNIPTAAGGASAFKKGLPDVINLKYELPPGGVGDPGGGSALPPNAIHSPLLVRSKTTLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSIFAGGGNGGGVASFNGSPLHHSVLFKPMLDSEQHHLQQQHHQQQQQQQHQQQLQHQQQQQQQQHQQQQQALKQEELLYDGEHLPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVAIATRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPGPLVNTAGMQGGESPGVGAFQYGGSVRSPYAAGGGGGVVSSQQMKVETNDGAGGMMMPGGGSNGGLNGMSNGPSADGNGGSSGGGNHMQPGIPVLLQEIMDVEPLWQYNAAELARLNQPPPAGNCTNIANNPLLCSAGISSESSPDLIANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSISTPGEIKISLGKSITLEQVKNSGLQTCIERMLNLTDHLRRLRVDKYEYVAMKVIVLLSSDTSELKESEKVRASQEKALQALQAYTLAYYPKSPAKFGELLLRIPELQRTCQVGKEMLNIKSKDDEEPSFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00107739;
90% Identity: iTF_00107739;
80% Identity: iTF_00109202; iTF_00096442; iTF_00109183;